Bioinformatics Analyst Cancer Genetics and Functional Genomics

Memphis, Tennessee
Posted 1 month ago

Overview

We are seeking a highly motivated and creative bioinformatics research analyst to join the team of Dr. Kim Nichols in the Division of Cancer Predispositon at St. Jude Children’s Research Hospital. The bioinformatics analyst will develop and apply innovative analytical approaches in the area of cancer genetics and functional genomics and have the unique opportunity to help carry out research studies that focus on known hereditary forms of childhood cancer and discovery of new causes for familial cancers.

You will work closely with research team members to analyze data such as WES, WGS, bulk and single cell RNA seq, Cut&Run seq and ATAC seq data, to identify novel cancer predisposition genes and interrogate their biological function. You will develop, improve, modify, and operate data analysis pipelines, generate and provide analysis results and reports, and perform requested custom analyses.

The department provides a highly interactive environment with collaborative opportunities, access to high performance computing clusters, a cloud computing environment, innovative visualization tools, highly automated analytical pipelines and mentorship from scientists with interests experience in data analysis, data management and delivery of high-quality results. The Division of Cancer Predisposition supports strong teamwork as well as individual and personal growth.

Candidates with a strong background and interest in genetics, cancer biology, hematopoiesis, and experience with use of genetic approaches to understand disease pathogenesis are highly encouraged to apply for this position. Familiarity with statistical genetics/genomics software including MERLIN, PLINK, GATK, EdgeR, samtools is preferred. This position is a forecasted position located in Memphis, TN, and relocation assistance is available.

Responsibilities

  • Performs basic analysis of biomedical data produced from a variety of next generation sequencing platforms under close supervision
  • Basic statistical analysis, algorithm implementation, bioinformatics programming.
  • Implement in-house bioinformatic workflows to analyze functional genomics data including as RNAseq, ChIPseq, WGS/WES.
  • Improve existing analysis workflows by mining published research
  • Help the investigators prepare manuscripts and grant applications
  • Communicates to project managers on the design and implementation of an analytical process, and progress of project.
  • Maintains regular and predictable attendance.
  • Performs other related duties as assigned in order to meet the goals of the department and institution.

Minimum Education

  • Bachelor’s degree is required. Master’s degree or PHD is preferred

Minimum Experience

  • Two (2) years of relevant experience is required.
  • No experience may be acceptable with a Master’s degree in Computer Science or Bioinformatics, with a background in the biological sciences.
  • Experience in programming (Python, Java, C/C++, perl or other programming/scripting languages) under Linux/Unix environment is required.
  • Experience of data analyses under supervision is required.
  • End user support and training experience is preferred.
  • Experience with open source software development is preferred.
  • Experience in development of algorithms, statistical methods or scientific software is preferred.
  • Experience in next-generation sequence analysis is preferred.
  • Experience working on a team project is preferred.
  • Scripting experience using a statistics package such as R, S-Plus or SAS is preferred

What We Offer

Salary is highly competitive (comparable to industry) and employee benefits are outstanding. Relocation assistance is available. Working at St. Jude provides the opportunity to make a tangible difference to pediatric cancer patient care and survival and St. Jude has been consistently ranked in Fortune magazine’s “ 100 Best Places to Work ” list and is exceptionally positively reviewed on GlassDoor.

COVID-19 Vaccine

As of September 10, 2021, St. Jude Children’s Research Hospital has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment.

EEO Statement

St. Jude is an Equal Opportunity Employer

No Search Firms

St. Jude Children’s Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

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