Publications From Our Bioinformaticians
Our bioinformaticians understand the challenges faced by bench biologists and enjoy using their expertise to help others. Some of their published scientific contributions are listed below.
Core liver homeostatic co-expression networks are preserved but respond to perturbations in an organism- and disease-specific manner.
Saeed Esmaili, Peter Langfelder, T. Grant Belgard, Daniele Vitale, Mahmoud Karimi Azardaryany, Ghazal Alipour Talesh, Mehdi Ramezani-Moghadam, Vikki Ho, Daniel Dvorkin, Suat Dervish, Brian S. Gloss, Henning Grønbæk, Christopher Liddle, Jacob George
Francisco Pestana, Gabriela Edwards-Faret, T Grant Belgard, Araks Martirosyan, Matthew G Holt et al. Brain Sciences (2020).
Genome-wide changes in lncRNA, alternative splicing, and regional gene expression patterns in autism
Neelroop N Parikshak*, Vivek Swarup*, T Grant Belgard*, Manuel Irimia, et al. Nature (2016).
CSN and CAVA: variant annotation tools for rapid, robust next-generation sequencing analysis in the clinical setting
FUS pathology in ALS is linked to alterations in multiple ALS-associated proteins and rescued by drugs stimulating autophagy
Lara Marrone, Hannes C A Drexler, Jie Wang, Priyanka Tripathi, Tania Distler, Patrick Heisterkamp, Eric Nathaniel Anderson, Sukhleen Kour, Anastasia Moraiti, Shovamayee Maharana, Rajat Bhatnagar, T Grant Belgard, et al. Acta Neuropathologica (2019).
Adult pallium transcriptomes surprise in not reflecting predicted homologies across diverse chicken and mouse pallial sectors
T Grant Belgard*, Juan F Montiel, Wei Zhi Wang, Fernando Garcia-Moreno, Elliott H Margulies, Chris P Ponting*, Zoltán Molnár*. Proceedings of the National Academy of Sciences of the United States of America (2013). (free PDF)
Thomas M Keane, Leo Goodstadt, Petr Danecek, Michael A White, Kim Wong, Binnaz Yalcin, Andreas Heger, Avigail Agam, Guy Slater, Martin Goodson, Nicholas A Furlotte, Eleazar Eskin, Christoffer Nellåker, Helen Whitley, James Cleak, Deborah Janowitz, Polinka Hernandez-Pliego, Andrew Edwards, T Grant Belgard, et al. Nature (2011).
Analysis of B cell repertoire dynamics following hepatitis B vaccination in humans, and enrichment of vaccine- specific antibody sequences
Significant transcriptional changes in 15q duplication but not Angelman syndrome deletion stem cell-derived neurons
Nora Urraca, Kevin Hope, A Kaitlyn Victor, T Grant Belgard, Rawaha Memon, Sarita Goorha, Colleen Valdez, Quynh T Tran, Silvia Sanchez, Juanma Ramirez, Martin Donaldson, Dave Bridges, Lawrence T Reiter. Molecular Autism (2018).
An Immunoaffinity-Based Method for Isolating Ultrapure Adult Astrocytes Based on ATP1B2 Targetting by the ACSA-2 Antibody
Mykhailo Y. Batiuk, Filip de Vin, Sandra I. Duqué, Chen Li, Takashi Saito, Takaomi Saido, Mark Fiers, T. Grant Belgard, Matthew G. Holt. The Journal of Biological Chemistry (2017).
In-depth assessment of within-individual and inter-individual variation in the B cell receptor repertoire
The Quality Sequencing Minimum (QSM): providing comprehensive, consistent, transparent next generation sequencing data quality assurance
Elevated gene expression of most microglial markers, and reduced expression of most pyramidal neuron and interneuron markers, in postmortem autism cortex
Rebeca Borges-Monroy, Chris Ponting*, T Grant Belgard*. bioRxiv preprint (2015).
Wenjie Sun, Jeremie Poschmann, Ricardo Cruz-Herrera del Rosario, Neelroop N Parikshak, Hajira Shreen Hajan, Vibhor Kumar, Ramalakshmi Ramaswamy, T Grant Belgard, et al. Cell (2016).
Plasma cell antibody repertoire analysis following administration of meningococcal polysaccharide and protein-polysaccharide conjugate vaccines: evidence of distinct patterns of B cell activation
Endothelium-derived extracellular vesicles promote splenic monocyte mobilisation in myocardial infarction
Naveed Akbar, Janet Digby, Thomas J Cahill, Abhijeet N Tavare, Alastair L Corbin, Sushant Saluja, Sam Dawkins, Laurienne Edgar, Nadiia Rawlings, Klemen Ziberna, Eileen McNeill, Oxford Acute Myocardial Infarction (OxAMI) Study, Errin Johnson, Alaa A Aljabali, Rebecca A Dragovic, Mala Rohling, T Grant Belgard, et al. JCI Insight (2017).
Expression profiling of mouse subplate reveals a dynamic gene network and disease association with autism and schizophrenia
Anna Hoerder-Suabedissen, Franziska M Oeschger, Michelle L Krishnan, T Grant Belgard, et al. Proceedings of the National Academy of Sciences of the United States of America (2013).