Bioinformatics Jobs

Current Employees: If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click here to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position using the Career worklet, please review this tip sheet. The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Bioinformatics Analyst (Cheminformatics) to work the UHealth Medical Campus in Miami, FL 33146. CORE JOB SUMMARY The Bioinformatics Analyst works with research staff to extend capabilities in bioinformatics and improve understanding of genetic variation in human health and disease. The Bioinformatics Analyst maintains and performs analysis with existing pipelines while assisting and benchmarking the development of novel methods. CORE JOB FUNCTIONS ● Runs and maintains existing next generation data analysis pipelines. ● Assists senior bioinformatics analysts in pipeline and algorithm development and validation. ● Extracts features of interest from data relating to specific biological questions. ● Contributes to the maintenance of genomic and clinical databases. ● Performs statistical and integrative data analysis on genomics and clinical data. ● Works along-side other team members and data analysts. ● Follows standard operating procedures, documentation, and scripts to generate reports. ● Adheres to University and unit-level policies and procedures and safeguards University assets. This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary. CORE QUALIFICATIONS Education: PhD degree in relevant field Experience: Minimum 1 year of relevant experience Knowledge, Skills and Attitudes: ● Skill in collecting, organizing, and analyzing data. ● Ability to recognize, analyze, and solve a variety of problems. ● Ability to exercise sound judgment in making critical decisions. ● Ability to process and handle confidential information with discretion. ● Proficiency in computer software. Department Specific Functions & Qualifications The Sylvester Comprehensive Cancer Center & the Department of Molecular and Cellular Pharmacology are actively seeking a full-time Bioinformatics / Cheminformatics Analyst to work on the UHealth campus in Downtown Miami. At Sylvester, we are at the cutting edge of healthcare innovation, leveraging artificial intelligence and machine learning to transform drug discovery and development. Our mission is to accelerate the delivery of therapeutic solutions to patients through state-of-the-art technology and groundbreaking research. The Analyst will leverage expertise in computational chemistry, bioinformatics, and AI to process and analyze large-scale biomedical, small molecule bioactivity, structural biology, image, and clinicogenomic datasets, integrating them with the Sylvester Data Portal. The successful candidate will work within an interdisciplinary team of research scientists, data engineers, and full-stack developers, using state-of-the-art software development practices to enhance the university’s research activities. Primary Responsibilities: ● Process and analyze large-scale multi-omics and drug discovery datasets (WES, WGS, bulk/single-cell RNA-Seq, ATAC-Seq, Drug Screening, CRISPR Screening). ● Develop and maintain production-grade pipelines for processing and analysis of diverse biomedical datasets. ● Develop visualization and bioinformatic analysis tools for exploring diverse biomedical data. ● Integrate developed tools and pipelines with Sylvester’s internal end-user data analytics platform. ● Apply state-of-the-art AI, bioinformatics, and biostatistics approaches to cancer precision medicine. ● Write standard operating procedures and other relevant documentation. ● Develop and apply AI/ML models for structure-based and ligand-based drug design. ● Utilize computational tools to predict and optimize pharmacokinetic (PK) and pharmacodynamic (PD) properties of drug candidates. ● Design and implement algorithms to identify novel drug candidates and elucidate their mechanisms of action. ● Integrate and analyze large-scale biological, chemical, and clinical datasets to extract insights and inform drug discovery decisions. ● Collaborate with cross-functional teams to advance drug discovery projects. ● Analyze and interpret PK/PD data using advanced statistical and modeling software. ● Stay updated with advancements in computational chemistry, AI, and bioinformatics. ● Contribute to the development of new computational tools and methodologies. ● Present findings to both technical and non-technical stakeholders. ● Participate in scientific discussions and strategy meetings, providing AI/ML expertise. ● Author scientific papers, reports, and patents related to AI/ML in drug discovery. Preferred Requirements ● PhD or MSc degree in computational chemistry, computational biology, medicinal chemistry, pharmaceutical sciences, computational sciences, or a related field. ● Fluency in R or Python and Unix (bash). ● Experience with analyzing and interpreting different omics and/or drug discovery datasets (WES, WGS, bulk/single-cell RNA-Seq, ATAC-Seq, Drug Screening, CRISPR Screening). ● Experience with using common open-source bioinformatics/NGS workflows (BWA, STAR, Picard, GATK, etc.). ● Familiarity with machine learning frameworks (e.g., Scikit-learn, TensorFlow, PyTorch), and developing and deploying machine learning models. ● Highly motivated, strong work ethic, and able to work independently and with a team. ● Excellent skills in communication, organization, and time management. Preferred Qualifications ● For Ph.D. holders: 0-3 years of relevant experience in computational chemistry, AI, and drug discovery. ● Deep expertise with chemical toolkits such as DeepChem, ChemAxon, OEChem, or RDKit. ● Familiarity with drug discovery databases (CTRP, GDSC, PRISM, CCLE, DepMap, LINCS) and publicly available clinicogenomic datasets (CPTAC, TCGA, AACR Project GENIE, etc.). ● Experience with Cloud Computing Environments (e.g., Azure). ● Familiarity with relational (e.g., PostgreSQL) and/or NoSQL databases (e.g., MongoDB). ● Familiarity with container technologies (e.g., Docker). ● Experience with Generative AI tools and techniques. ● Familiarity with High Performance Computing. ● Familiarity with version control (Git). #LI-YC1 The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more. UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for. The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information. Job Status: Full time Employee Type: Staff Pay Grade: A9

Job Advert: Lead Bioinformatics Scientist Job Title: Lead Bioinformatics Scientist Job Type: Permanent Salary: $180,000–$200,000 USD per year + bonus Role Location: San Francisco, CA (hybrid role) Visa Requirements: No sponsorship provided. The Company: Our client is an emerging leader within biotechnology, headquartered in the vibrant tech hub of San Francisco, California. Their mission is to empower scientists worldwide by accelerating biotech research through innovative DNA sequencing and analysis tools. Every day, thousands of innovators—including Nobel Prize winners, biotech startups, and research labs—rely on their solutions to drive world-changing discoveries in healthcare, sustainability, and beyond. In 2024, they saved researchers 2 million hours, transforming their productivity. Join their dynamic, collaborative team to shape the future of science. Role and Responsibilities: As the Lead Bioinformatics Scientist, you’ll lead the charge in building cutting-edge bioinformatics workflows that power faster, smarter science. Collaborating with a passionate team of scientists, bioinformaticians, and software engineers, you’ll drive innovation and mentor others in a creative, high-impact environment. Your key responsibilities include: • Designing and optimizing high-performance bioinformatics pipelines for processing thousands of daily samples, leveraging tools like Snakemake and cloud deployments. • Innovating sequence analysis workflows for bulk/single-cell RNAseq, differential gene expression, and large-scale genomics, ensuring robust and scalable solutions. • Troubleshooting complex sequencing data challenges, from biological artifacts to platform-specific issues, to ensure reliable outputs. • Developing intuitive web tools (e.g., Streamlit, R Shiny) and data visualizations to transform raw bioinformatics data into actionable insights. • Providing thought leadership and mentoring junior team members, fostering a culture of innovation and collaboration. • Staying ahead of industry trends, integrating emerging bioinformatics tools to enhance our offerings for biopharma and research clients. Job Requirements: • Education and Experience: PhD in Biological Sciences, Bioinformatics, Computational Biology, or related field, with 8+ years of experience developing production-level bioinformatics pipelines. • Required Qualifications: • Deep expertise in analyzing bulk/single-cell RNAseq data and performing differential gene expression using state-of-the-art tools. • Significant experience building production-level Snakemake (or Nextflow) pipelines, with local and cloud-based deployments. • Strong knowledge of sequence analysis (alignment, assembly) and molecular biology, with experience in Oxford Nanopore and Illumina sequencing. • Proficiency in Python (numpy, pandas, Jupyter, Biopython) and package management (e.g., Conda). • Hands-on experience with Docker, Apptainer, or Singularity for containerized workflows. • Expertise in Git/GitHub and Linux shell scripting for version control and automation. • Proficiency in developing intuitive web tools for bioinformatics reporting (e.g., R Shiny, Streamlit). • Familiarity with public genomic data repositories (e.g., NCBI, Ensembl) and large-scale genomic data processing. • Strong communication skills and ability to write clean, maintainable, production-ready code. • Preferred Qualifications: • Experience with compiled languages (C++, Rust) for performant software development. • 1+ year of molecular biology wet lab experience. • Demonstrated ability to develop novel bioinformatics algorithms. • Strong interest in creating intuitive data visualizations for scientific insights. Benefits: • Competitive Compensation: Highly competitive remuneration. • Generous Time Off: 4 weeks paid time off + 10 paid holidays. • Comprehensive Health Coverage: Health, dental, and vision insurance, plus life insurance and mental health coverage. • Retirement and Wellness: 401(k) with matching, Health Advocate services, and gym membership. • Impactful Work: Contribute directly to accelerating biotech research, supporting novel therapies and sustainability. • Innovative Environment: Work with cutting-edge tools (e.g., Snakemake, Streamlit, AWS) and collaborate with top-tier researchers. • Supportive Culture: Join a passionate, inclusive team that values creativity, mentorship, and professional growth. Accessibility Statement: Read and apply for this role in the way that works for you by using our Recite Me assistive technology tool. Click the circle at the bottom right side of the screen and select your preferences. We make an active choice to be inclusive towards everyone every day. Please let us know if you require any accessibility adjustments through the application or interview process. Our Commitment to Diversity, Equity, and Inclusion: Our mission is to empower every person, regardless of their background or circumstances, with an equitable chance to achieve the careers they deserve. Building a diverse future, one placement at a time. Check out our DE&I page here

Description Leidos Public Health Division has a 3-month paid fellowship program for a PhD student scientist specialized in Bioinformatics science and pipeline development. The graduate fellow will work with Leidos on bioinformatics projects of public health importance. The ideal candidate will have strong experience in Transcriptomics, NGS data analysis, including QC, assembly, annotation, alignment, variant detection, and preferably phylogenetic analysis of microbial genomes and metagenomes. Extensive hands-on experience with bioinformatics pipeline development using Nextflow is expected. This fellowship may be extended beyond 3 months and is open to telecommuting, location preferred Atlanta, GA. Responsibilities • Develop, test, and deploy bioinformatics data pipelines and workflows using Nextflow. • Develop and execute bioinformatics algorithms and workflows in HPC (high-performance computing) environments. • Write customs scripts and software to perform bioinformatics analysis using Python, Perl and/or R. • Perform bioinformatics analysis using open-source bioinformatics tools as well as licensed proprietary software such as CLC Genomics Workbench and Geneious. Support modeling and simulation of evolutionary and population bological process using Bayesian inference and/or genetic algorithms. • Use statistical analysis tools, interpret and communicate results. • Develop tools for visualizing complex biological datasets and able to interpret and communicate results as well as uncertainty to a diverse group of customers. • Develop and maintain highly curated genomic sequence databases, signature databases for virulence and AMR markers, strain type and pathogen type markers. • Work together with the DevOps team in adopting best software engineering practices for tool and workflow development. • Assist with developing standard operating procedures for bioinformatics analyses. • Supports public health researchers in creating and submitting publication and poster presentations. MINIMUM QUALIFICATIONS: • A PhD candidate in their advanced state (e.g. 4th or 5th year) of their study in bioinformatics, genomics, molecular biology, genetics or related field. • 2+ years of hands-on bioinformatics experience through academic or research work. • Experience in developing pipelines using Nextflow (primary), Snakemake, and/or Workflow Description Language (WDL). • Experience with processing of high-throughput data and possessing strong data management and analysis skills. • Experience working in Linux environments and broad experience with open source bioinformatics tools. • Proficient coding/scripting in Python, R, Perl • Experience working in a high-performance computing environment • Strong communication skills PREFERRED QUALIFICATIONS: • A PhD candidate in their advanced state (e.g. 4th or 5th year) of their study in bioinformatics, genomics, molecular biology, genetics or related field. • Hands on bioinformatics development experience in public health. • Experience in designing and conducting training workshops to the bioinformatics community on latest bioinformatics methods and concepts. • Previous internship or fellowship experience at the CDC or other public health agencies. ELIGIBILITY Applicants should demonstrate a strong interest in careers focused on bioinformatics development and public health. To be eligible, candidates must: • Be a U.S. citizen • A current Ph.D. candidate (expecting to graduate in 2025 or 2026) in bioinformatics, genomics, molecular biology, genetics, or a closely related field from an accredited institution • Be able to successfully pass a background check for CDC clearance • Successfully complete a bioinformatics development exercise Location: 100% remote with preference for metro Atlanta, GA Original Posting: July 14, 2025 For U.S. Positions: While subject to change based on business needs, Leidos reasonably anticipates that this job requisition will remain open for at least 3 days with an anticipated close date of no earlier than 3 days after the original posting date as listed above. Pay Range: Pay Range $55,250.00 - $99,875.00 The Leidos pay range for this job level is a general guideline only and not a guarantee of compensation or salary. Additional factors considered in extending an offer include (but are not limited to) responsibilities of the job, education, experience, knowledge, skills, and abilities, as well as internal equity, alignment with market data, applicable bargaining agreement (if any), or other law. #Remote

We're hiringBioinformatics Scientists with strong backgrounds in database development, management and analysis as they relate to human health and disease biomarkers, with the goal of improving disease prediction and prevention. With ICR, you'll get to: • Design, build, test and refine multiple large biomarker databases in collaboration with multiple ICR teams • Work with biological data analysts to access and improve large databases of health and disease biomarkers for use in predictive analytics and predictive modeling • Conduct complex bioinformatics analyses on large genomic, transcriptomic and epigenetic data from biofluids and cell lines as well as large protein, cfDNA, miRNA and epigenetic datasets • Design and build streamlined pipelines and algorithms for database querying and multiple other applications to support complex dataset analyses Please apply if you have: • An advanced degree in Bioinformatics or Computer Sciences with a focus on database architecture, access and querying • Extensive database architecture experience (e.g. SQL, MySQL, etc) • Extensive programming experience and intimate knowledge of programming languages for statistical analysis • Experience mining, analyzing and exploring genomic, epigenetic, transcriptomic (RNAseq), proteomic, metabolomic, and other -omic datasets Ideally, you'll also have: • Extensive working knowledge of various AI/machine-learning algorithms and their implementation in biological dataset analysis • A solid understanding of and appreciation for Bayesian statistics and methods • Personal interest in using statistics to evaluate disease models and aging biology And you'll need: • Ability to work in the United States without sponsorship • A can-do attitude and a friendly, easygoing personality Salary Starting base pay range: $155,000/yr - $230,000/yr Starting additional compensation range: $10,000/yr - $30,000/yr Starting position title and compensation are commensurate with experience.

SHIFT: Day (United States of America) Bioinformatics Engineer I – Children’s Hospital of Philadelphia (Philadelphia, PA): Support computational environments focused on the management, transfer, formatting, and processing of complex data types associated with genomics and proteomics. Support the bioinformatics analytical groups and assist in the implementation of basic systems for data manipulation and analysis pipelines, applications, and bioinformatics-specific hardware configurations. Collaborate with bioinformatics group members to develop functioning pipelines upstream of customized analysis workflow, maintain data pipelines, and execute development testing for commonly used applications. Partner with cross-functional teams to gather requirements, plan, and execute the development of platforms that support healthcare research. Develop infrastructure automation for efficient resource management across multiple environments using Terragrunt and Terraform. Deploy and maintain scalable Kubernetes-based applications, ensuring secure and high-performance applications in production, and facilitating large-scale data analysis and research. Assist with building and maintaining secure cloud environments for the Arcus research platforms, ensuring robust data privacy and compliance with healthcare regulations. Requires a Bachelor’s degree in Bioinformatics or a related field and 1 year of experience working with bioinformatics data, Cloud infrastructure, and containerization, including developing bioinformatics pipelines in a Cloud environment and building ETL pipelines to transfer NGS/bioinformatics data, using Infrastructure as Code (IaC) to manage IT infrastructure, and Docker for containerization, as well as LINUX, R and Python. Telecommuters considered. Travel (<5%) for quarterly meetings. Send resumes to: oivs@chop.edu. #LI-DNI At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.

Current Employees: If you are a current Staff, Faculty or Temporary employee at the University of Miami, please click here to log in to Workday to use the internal application process. To learn how to apply for a faculty or staff position using the Career worklet, please review this tip sheet. The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Bioinformatics Analyst (Cheminformatics) to work the UHealth Medical Campus in Miami, FL 33146. CORE JOB SUMMARY The Bioinformatics Analyst works with research staff to extend capabilities in bioinformatics and improve understanding of genetic variation in human health and disease. The Bioinformatics Analyst maintains and performs analysis with existing pipelines while assisting and benchmarking the development of novel methods. CORE JOB FUNCTIONS ● Runs and maintains existing next generation data analysis pipelines. ● Assists senior bioinformatics analysts in pipeline and algorithm development and validation. ● Extracts features of interest from data relating to specific biological questions. ● Contributes to the maintenance of genomic and clinical databases. ● Performs statistical and integrative data analysis on genomics and clinical data. ● Works along-side other team members and data analysts. ● Follows standard operating procedures, documentation, and scripts to generate reports. ● Adheres to University and unit-level policies and procedures and safeguards University assets. This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary. CORE QUALIFICATIONS Education: PhD degree in relevant field Experience: Minimum 1 year of relevant experience Knowledge, Skills and Attitudes: ● Skill in collecting, organizing, and analyzing data. ● Ability to recognize, analyze, and solve a variety of problems. ● Ability to exercise sound judgment in making critical decisions. ● Ability to process and handle confidential information with discretion. ● Proficiency in computer software. Department Specific Functions & Qualifications The Sylvester Comprehensive Cancer Center & the Department of Molecular and Cellular Pharmacology are actively seeking a full-time Bioinformatics / Cheminformatics Analyst to work on the UHealth campus in Downtown Miami. At Sylvester, we are at the cutting edge of healthcare innovation, leveraging artificial intelligence and machine learning to transform drug discovery and development. Our mission is to accelerate the delivery of therapeutic solutions to patients through state-of-the-art technology and groundbreaking research. The Analyst will leverage expertise in computational chemistry, bioinformatics, and AI to process and analyze large-scale biomedical, small molecule bioactivity, structural biology, image, and clinicogenomic datasets, integrating them with the Sylvester Data Portal. The successful candidate will work within an interdisciplinary team of research scientists, data engineers, and full-stack developers, using state-of-the-art software development practices to enhance the university’s research activities. Primary Responsibilities: ● Process and analyze large-scale multi-omics and drug discovery datasets (WES, WGS, bulk/single-cell RNA-Seq, ATAC-Seq, Drug Screening, CRISPR Screening). ● Develop and maintain production-grade pipelines for processing and analysis of diverse biomedical datasets. ● Develop visualization and bioinformatic analysis tools for exploring diverse biomedical data. ● Integrate developed tools and pipelines with Sylvester’s internal end-user data analytics platform. ● Apply state-of-the-art AI, bioinformatics, and biostatistics approaches to cancer precision medicine. ● Write standard operating procedures and other relevant documentation. ● Develop and apply AI/ML models for structure-based and ligand-based drug design. ● Utilize computational tools to predict and optimize pharmacokinetic (PK) and pharmacodynamic (PD) properties of drug candidates. ● Design and implement algorithms to identify novel drug candidates and elucidate their mechanisms of action. ● Integrate and analyze large-scale biological, chemical, and clinical datasets to extract insights and inform drug discovery decisions. ● Collaborate with cross-functional teams to advance drug discovery projects. ● Analyze and interpret PK/PD data using advanced statistical and modeling software. ● Stay updated with advancements in computational chemistry, AI, and bioinformatics. ● Contribute to the development of new computational tools and methodologies. ● Present findings to both technical and non-technical stakeholders. ● Participate in scientific discussions and strategy meetings, providing AI/ML expertise. ● Author scientific papers, reports, and patents related to AI/ML in drug discovery. Preferred Requirements ● PhD or MSc degree in computational chemistry, computational biology, medicinal chemistry, pharmaceutical sciences, computational sciences, or a related field. ● Fluency in R or Python and Unix (bash). ● Experience with analyzing and interpreting different omics and/or drug discovery datasets (WES, WGS, bulk/single-cell RNA-Seq, ATAC-Seq, Drug Screening, CRISPR Screening). ● Experience with using common open-source bioinformatics/NGS workflows (BWA, STAR, Picard, GATK, etc.). ● Familiarity with machine learning frameworks (e.g., Scikit-learn, TensorFlow, PyTorch), and developing and deploying machine learning models. ● Highly motivated, strong work ethic, and able to work independently and with a team. ● Excellent skills in communication, organization, and time management. Preferred Qualifications ● For Ph.D. holders: 0-3 years of relevant experience in computational chemistry, AI, and drug discovery. ● Deep expertise with chemical toolkits such as DeepChem, ChemAxon, OEChem, or RDKit. ● Familiarity with drug discovery databases (CTRP, GDSC, PRISM, CCLE, DepMap, LINCS) and publicly available clinicogenomic datasets (CPTAC, TCGA, AACR Project GENIE, etc.). ● Experience with Cloud Computing Environments (e.g., Azure). ● Familiarity with relational (e.g., PostgreSQL) and/or NoSQL databases (e.g., MongoDB). ● Familiarity with container technologies (e.g., Docker). ● Experience with Generative AI tools and techniques. ● Familiarity with High Performance Computing. ● Familiarity with version control (Git). #LI-YC1 The University of Miami offers competitive salaries and a comprehensive benefits package including medical, dental, tuition remission and more. UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for. The University of Miami is an Equal Opportunity Employer - Females/Minorities/Protected Veterans/Individuals with Disabilities are encouraged to apply. Applicants and employees are protected from discrimination based on certain categories protected by Federal law. Click here for additional information. Job Status: Full time Employee Type: Staff Pay Grade: A9 The mission of the University of Miami is to transform lives through education, research, innovation, and service. A vibrant and diverse academic and healthcare community, the University of Miami and the University of Miami Health System ("UHealth") have rapidly progressed to become one of the nation’s top research universities and academic medical centers in the nation. The University comprises 12 schools and colleges serving undergraduate and graduate students in more than 350 majors and programs. Visit welcome.miami.edu/about-um to learn more about our points of pride. The University ranks No. 55 on U.S. News & World Report’s 2022 Best Colleges list and ranked No. 49 in the 2022 Wall Street Journal/Times Higher Education College Rankings. Bascom Palmer Eye Institute is ranked the #1 eye hospital in the USA and offers some of the nation's premiere eye doctors to treat every eye condition for adults. Sylvester Comprehensive Cancer, part of the Miller School of Medicine, received the prestigious National Cancer Institute designation in 2019. The University of Miami and UHealth have also ranked among the Forbes Best Employers and Best Employers for Women on several occasions, most recently in 2022. Transforming lives With more than 17,000 faculty and staff, the University strives for excellence, and is driven by a powerful mission to transform and impact the lives of its students, patients, members of the community, and people across the globe. The University is committed to fostering a culture of belonging, where everyone feels valued and has the opportunity to add value. Through values of Diversity, Integrity, Responsibility, Excellence, Compassion, Creativity, and Teamwork (DIRECCT) the U community works together to create an environment driven by purpose, excellence, community, and service.

Be at the forefront of the gene editing revolution and contribute to developing next generation therapies for children. Top-tier compensation and benefits, supportive and collaborative team environment with unique opportunities and exciting potential for career advancement. As part of the Structural Biology Department at St. Jude Children's Research Hospital , the Kellogg lab seeks a talented computational biologist who is looking to make high-impact contributions on exciting challenges at the scientific frontier of genome-editing. The Kellogg lab uses cutting edge genetics, cryo-electron microscopy, machine-learning, and protein design to develop novel transposon-based genome-editing tools. Located on the 6th floor of the new Inspiration4 Advanced Research Center (opened in 2021), the Kellogg lab leads the forefront of research in understanding the biology of CRISPR-associated transposons ( Science, 2023 , Molecular Cell, 2023 , Science, 2023 , Nature, 2023 , PNAS, 2022 , Science, 2021 , and more ) and is well supported by the NIH, Pew Biomedical Foundation, and the Cystic Fibrosis Foundation to develop novel approaches to engineer programmable transposons for clinical gene replacement therapy. The Kellogg lab is a highly interdisciplinary scientific environment, routinely working with generously supported St. Jude research core facilities: Cryo-EM Center , the Protein Technology Center , the Single-Molecule Imaging Center , the Center for Advanced Genome Editing , and the Cell & Tissue Imaging Center . The Kellogg lab is a scientifically enriching environment with regular CRISPR supergroup discussions with Dr. Shengdar Tsai . In addition, the Kellogg lab is an active member of RosettaCommons and the Rosetta community. In this position, the candidate will be exposed to multiple, cutting edge techniques spanning cryo-electron microscopy, computational protein design, machine learning, and advanced genomics in a world class research environment aimed at advancing cures for genetic disorders. About you The successful candidate will be an independent learner with strong critical thinking skills and excellent communication skills. We are looking for someone with an outstanding independent track-record and stellar academic background. The ideal candidate is passionate about research and committed to developing tomorrow's cures for children with devastating genetic disorders. Our ideal candidate has extensive experience in one of the following (or more): bioinformatic analyses (metagenomic mining is a major plus), reconstructing evolutionary trajectories, mining transposable element databases, etc.. Scientists are expected to operate independently by leading new research directions in the Kellogg lab. The candidate will be mentored in manuscript preparation and be given opportunities for career advancement via conference attendance and oral presentation sponsorship. Responsibilities: • Develop new research directions under close mentorship of Dr. Kellogg. • Stay up to date with latest CRISPR and protein engineering literature, conduct regular literature reviews in collaboration with Dr. Kellogg and other Kellogg lab members. • Collaborate with other Kellogg lab members to design & clone large DNA libraries using state of the art machine learning methods • Map phylogenetic relationships of CRISPR-associated systems to map functional interactions. • Develop innovative sequence profile machine-learning based protein design pipelines in collaboration with Dr. Kellogg • Collaborate with Kellogg lab members to develop novel tools/assays to collectively advance lab research goals. • Mentor Kellogg lab members in executing internally developed computational analyses and pipelines. • Prepare manuscripts and present research at relevant conferences, including but not limited to: CRISPR, genome-engineering, or protein design conferences. Opportunities for Professional Growth • The candidate will be given opportunities to participate in interdisciplinary scientific research and be mentored in developing leadership skills. • The candidate will be given opportunities to develop new skills, including experimental biochemistry and/or structure determination in collaboration with Kellogg lab members. • The candidate will be given opportunities to attend diverse scientific conferences in the areas of computational protein design (including the Rosetta community), machine learning, genome-editing, and transposon biology. • The candidate will be given opportunities for oral presentations at local and national venues as well as opportunities to develop independent research directions. St Jude Children's Research Hospital is consistently named as one of Fortune magazine's "Best Companies to Work for" and top 10 "Best Places to Work in Academia" by the Scientist Magazine. St Jude is located in Memphis, Tennessee, the 28th most populous city in America. Memphis is a historic city with an affordable cost of living along with world class dining and strong cultural tradition in music and theater. Memphis enjoys a mild, sunny climate year-round and has some of the largest outdoor green spaces of any big city. St. Jude Employees receive: • Competitive compensation packages commensurate with experience. • Excellent healthcare plans with zero to low health premium costs. • Generous retirement benefits with contributions from St. Jude • Onsite health clinic, pharmacy, and exercise facilities. • Paid parental leave and adoption assistance. • Immigration Services • Tuition Reimbursement The Kellogg lab is committed to building a lab culture that is based on respect, diversity, and inclusion which contributes to a dynamic, innovative, and creative scientific environment that is fundamentally based on empathy and intellectual curiosity. The Kellogg lab is known for their rigor and fast pace, consistently aiming for ambitious goals that greatly expand the boundaries of human knowledge. The Kellogg lab is proud to be home to ambitious, curious, and fun-loving scientists of all nationalities and backgrounds. Senior Bioinformatic Research Scientist Minimum Education • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Minimum Experience: • Minimum Requirement: Bachelor's degree with 7+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 5+ years of relevant post-degree experience (OR) PhD with 2+ years of relevant post-degree experience. • Significant experience in at least one programming or scripting language. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Bioinformatics Research Scientist. Explore our exceptional benefits ! Bioinformatic Research Scientist Minimum Education: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Minimum Experience: • Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience. • Experience in at least one programming or scripting language. This Position May be Ideal For: • Ph.D.s with post-degree experience looking to establish an experimental line of inquiry before pursuing an independent research position. • Experienced Computational Biologists looking for a stimulating, collaborative, and interdisciplinary lab environment committed to creating tomorrow's genome-editing tools. To virtually meet Dr. Kellogg, check out The Plunge , a Cryo-EM Podcast she and two colleagues hosted. Dr. Kellogg was also recently featured on Cryo-Talk to talk about her life & work. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Senior Scientist - Computational Biology and Bioinformatics, Kellogg Lab. Explore our exceptional benefits ! St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Details Open Date 07/03/2025 Requisition Number PRN16010N Job Title Bioinformatics Data Analyst I Working Title Bioinformatics Data Analyst I Job Grade F FLSA Code Administrative Patient Sensitive Job Code? Yes Type Non Benefited Staff / Student Temporary? No Standard Hours per Week 19 Full Time or Part Time? Part Time Shift Day Work Schedule Summary Monday – Friday (flexible hours) Is this a work study job? No VP Area U of U Health - Academics Department 00255 - Radiation Oncology Som Location Campus City Salt Lake City, UT Type of Recruitment External Posting Pay Rate Range 22.88 - 28.02 Close Date 08/30/2025 Priority Review Date (Note - Posting may close at any time) Job Summary We are seeking a highly motivated Data Scientist/Biostatistician with strong analytical skills and an interest in cancer research. The successful candidate will support innovative research focused on understanding and improving cancer outcomes in rural and urban populations utilizing large national datasets such as NHANES , NHIS , BRFSS , HINT survey, along with data from institutional Electronic Medical Records ( EMR ). Our multidisciplinary research will focus on mental health and rural populations , but will also addresses crucial issues such as cognition, fatigue, obesity, relationships, finances, professional reintegration, behaviors affecting recurrence risk, and overall patient well-being. This role uniquely combines data science, biostatistics, and research coordination responsibilities, offering significant opportunities for professional growth, academic publication, and contribution to impactful patient-centered outcomes research. Responsibilities Essential Functions: • Data Management and Analysis (70%): • Extract, clean, and integrate datasets from institutional EMR (Epic), public datasets (eg. NHIS , BRFSS , etc), and cancer-specific resources ( NCDB ). • Conduct statistical analyses (logistic regression, survival analysis, mixed-effects models, propensity matching, etc). • Apply data science techniques including visualization methods. • Prepare clear, publication-quality reports, tables, and figures for manuscripts and presentations. • Interview patients to elicit their healthcare experiences and needs. • Research Coordination and Regulatory Support (30%): • Prepare and manage IRB documentation for research protocols • Coordinate timelines, schedule research meetings, and track project milestones. • Assist in manuscript preparation, including drafting methods/results sections and managing submission processes. • Support grant application preparation, particularly in assembling preliminary data and documents. This job description is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job. Work Environment and Level of Frequency typically required Nearly Continuously: Office environment. Physical Requirements and Level of Frequency that may be required Nearly Continuously: Sitting, hearing, listening, talking. Often: Repetitive hand motion (such as typing), walking. Seldom: Bending, reaching overhead. Minimum Qualifications Bachelor’s of Science degree with a focus on Bioinformatics, Biostatistics, Computer Science or Molecular Biology or equivalency (one year of education can be substituted for two years of related work experience). Two years of experience in genomic data analysis required. Demonstrated human relations and effective communication skills also required. Software development experience in object oriented programming using Java, Python, and or C++ and familiarity with molecular biology, genomics and some biostatistics helpful. Master of Science degree or PhD in Bioinformatics, Computer Science and/or Life Sciences preferred. Applicants must demonstrate the potential ability to perform the essential functions of the job as outlined in the position description. Preferences • Concurrent expertise in Data Science and Biostatistics is required. • Bachelor’s of Science degree with a focus of Bioinformatics, Biostatistics, Computer Science or Data Science. • Master of Science Degree or PhD in Biostatistics, Bioinformatics, Computer Science and/or Life Sciences strongly preferred. • Previous experience with advanced analytic methods, data extraction, and coding. • Natural language processing ( NLP ), and machine learning abilities are a plus, but not required. • Experience working in cancer research or other clinical research domains. • Willingness and ability to learn. • Driven, detail oriented, independent, and a problem solver. • Strong fluency in English is required. • Strong interpersonal skills is required. • Residency in Utah is required. Special Instructions Summary Additional Information The University is a participating employer with Utah Retirement Systems (“URS”). Eligible new hires with prior URS service, may elect to enroll in URS if they make the election before they become eligible for retirement (usually the first day of work). Contact Human Resources at (801) 581-7447 for information. Individuals who previously retired and are receiving monthly retirement benefits from URS are subject to URS’ post-retirement rules and restrictions. Please contact Utah Retirement Systems at (801) 366-7770 or (800) 695-4877 or University Human Resource Management at (801) 581-7447 if you have questions regarding the post-retirement rules. This position may require the successful completion of a criminal background check and/or drug screen. The University of Utah values candidates who have experience working in settings with students and patients from all backgrounds and possess a strong commitment to improving access to higher education and quality healthcare for historically underrepresented students and patients. All qualified individuals are strongly encouraged to apply. Veterans’ preference is extended to qualified applicants, upon request and consistent with University policy and Utah state law. Upon request, reasonable accommodations in the application process will be provided to individuals with disabilities. The University of Utah is an Affirmative Action/Equal Opportunity employer and does not discriminate based upon race, ethnicity, color, religion, national origin, age, disability, sex, sexual orientation, gender, gender identity, gender expression, pregnancy, pregnancy-related conditions, genetic information, or protected veteran’s status. The University does not discriminate on the basis of sex in the education program or activity that it operates, as required by Title IX and 34 CFR part 106. The requirement not to discriminate in education programs or activities extends to admission and employment. Inquiries about the application of Title IX and its regulations may be referred to the Title IX Coordinator, to the Department of Education, Office for Civil Rights, or both. To request a reasonable accommodation for a disability or if you or someone you know has experienced discrimination or sexual misconduct including sexual harassment, you may contact the Director/Title IX Coordinator in the Office of Equal Opportunity and Affirmative Action ( OEO /AA). More information, including the Director/Title IX Coordinator’s office address, electronic mail address, and telephone number can be located at: https://www.utah.edu/nondiscrimination/ Online reports may be submitted at oeo.utah.edu https://safety.utah.edu/safetyreport This report includes statistics about criminal offenses, hate crimes, arrests and referrals for disciplinary action, and Violence Against Women Act offenses. They also provide information about safety and security-related services offered by the University of Utah. A paper copy can be obtained by request at the Department of Public Safety located at 1658 East 500 South.

Compensation: $115,000 - $140,000 per year. You are eligible for a Short-Term Incentive Plan with the target at 7.5% of your annual earnings; terms and conditions apply. BI Scientist II – Remote , USA This position is focused on developing and improving computational pipelines for analyzing large-scale genomic data, particularly in the context of clinical diagnostics and research innovation. This role requires a mix of development experience, biological knowledge, and statistical proficiency. Essential Functions • Develop and maintain bioinformatics tools and pipelines for NGS data analysis • Collaborate with clinical, research, and engineering teams to implement solutions for genomic interpretation • Optimize existing pipelines for performance, accuracy, and scalability • Support assay validation and documentation requirements for clinical accreditation • Participate in algorithm development to identify genetic variants including SNVs, CNVs, and SVs • Evaluate new tools and technologies relevant to genomic analysis • Other duties as assigned  Qualifications • PhD degree in Bioinformatics, Data Science, Machine Learning, Computer Science, Statistics, Biophysics, Computational Biology or a related discipline, with at least 2 years of post-doctoral or industry experience • Alternatively, MS degree in a related field with 4+ years of industry experience • 2+ years of experience in bioinformatics pipeline development and data analysis. Proven track record of building and deploying machine learning models in real-world applications • Experience in analyzing large and complex structured/unstructured datasets under time constraints • Experience in working with clinical variant data and variant effect prediction • Strong background in next-generation sequencing (NGS) technologies, including analysis of genetic variants • Strong background in bioinformatics tools and techniques (e.g., Illumina sequencing data, NGS pipelines) • Proficiency with programming languages such as Python, R, or Perl • Experience working in Unix/Linux environments • Third-gen long-read sequencing background strongly beneficial (e.g. PacBio/ONT) • Familiarity with cloud-based services (AWS, GCP) • Excellent written and verbal communication skills with the ability to clearly present technical results to non-technical stakeholders • Ability to work both independently and collaboratively within multidisciplinary teams Preferred • Familiarity with bioinformatics concepts, molecular biology, and genomics is preferred, but not required • Familiarity with large-scale data platforms and cloud-based infrastructure (AWS, Azure, GCP) is a plus • Experience with language models (LLMs) is a strong bonus About Us: Ambry Genetics Corporation is a CAP-accredited and CLIA-licensed molecular genetics laboratory based in Aliso Viejo, California. We are a genetics-based healthcare company that is dedicated to open scientific exchange so we can work together to understand and treat all human disease faster. At Ambry, everyone is welcome. A career at Ambry Genetics is a chance to be part of a dynamic company that aims to improve health by understanding the relationships between genetics and human disease. We earned our reputation as industry leaders by responsibly introducing cutting-edge genetic testing solutions and continually sharing what we learn with the global scientific community. At Ambry you will be learning, challenging yourself, and having fun while collaborating with teammates through the open exchange of ideas. Our outstanding benefits program includes 401k, medical, dental, vision, FSA, paid sick leave and generous paid time off (PTO) program. Ambry Genetics is an Equal Opportunity Employer (EOE) and we maintain a drug-free work environment. The Company believes in second chance employment. Qualified applicants with arrest or conviction history will be considered regardless of their arrest or conviction history, consistent with local laws such as Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. You do not need to disclose your criminal history or participate in a background check until a conditional job offer is made to you. After making a conditional offer and running a background check, if the Company is concerned about conviction that is directly related to the job, you will be given the chance to explain the circumstances surrounding the conviction, provide mitigating evidence, or challenge the accuracy of the background report. For the purpose of the above job description, “Essential Functions” are “Material Job Duties”. Our salary ranges are determined by role, level, and location. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position across all US locations. Within the range, individual pay is determined by work location and additional factors, including job-related skills, experience, and relevant education or training. All qualified applicants will receive consideration for employment without regard to race (and traits historically associated with race, including, but not limited to hair texture and protective hairstyles such as braids, locks, and twists), color, creed, religion, sex, sexual orientation, gender identity, gender expression (including transgender status), national origin, ancestry, age, marital status or protected veteran status and will not be discriminated against on the basis of disability, protected medical condition as defined by applicable state or local law, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. If you have a disability or special need that requires accommodation, please contact us at careers@ambrygen.com Ambry does not accept unsolicited resumes from individual recruiters, third party recruiting agencies, outside recruiters or firms without an executed contract in place. We are not responsible for any fees related to resumes that are unsolicited or are received by Ambry. Such resumes will be deemed the sole property of Ambry and will be processed accordingly. PRIVACY NOTICES To review Ambry’s Privacy Notice, Click here: https://www.ambrygen.com/legal/privacy-policy To review the California privacy notice, click here: California Privacy Notice | Ambry Genetics To review the UKG privacy notice, click here: California Privacy Notice | UKG

Description Position Summary: We are seeking a highly-skilled Bioinformatics Data Analyst to join our team. The ideal candidate will be responsible for retrieving managing and visualizing large datasets while developing custom applications and the integration of laboratory equipment. Minimum Skills Basic understanding of molecular biology protein biochemistry genetics. Employ bioinformatics tools and software such as Snapgene Geneious Genedata Biologics Pipebio or Benchling for data analysis and management Proficient in MS Excel and programming skill in languages such as SQL Python or R Expert in data retrieving wrangling and management of large datasets from databases. Ability to create dynamic and interactive data visualizers prior experience with any of these PowerBI Tableau D3.js and Spotfire Preferred Skills Working experience with related libraries in creating custom applications Pandas NumPy SciKit-lern Matplotlib Seaborn and Streamlit Prior experience with programming and integrating laboratory equipment for data capture Knowledge of the antibody or genetic medicine drug discovery and development process Qualifications: - A degree in Bioinformatics Computational Biology Data Science Computer Science or a related field is preferred. - Proven experience in data analysis visualization and the development of bioinformatics applications. - Strong problem-solving skills attention to detail and the ability to work collaboratively in a fast-paced environment. Education B.S. in a science discipline or bioinformatics and 3 years of experience or M.S. in a scientific discipline or bioinformatics and 2 years of experience.