Bioinformatics Jobs

Overview Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington... With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality. At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion. The Fong lab is seeking a highly qualified and motivated Bioinformatics Analyst to work in a collaborative environment leading research on the mechanisms of cancer immunotherapy response and resistance. The focus of our lab is to unravel the dynamic interactions governing the generation of anti-tumor immunity and apply this knowledge toward developing novel approaches for the study and treatment of cancer. We are searching for an analyst with an interest in developing pipelines for quality control and end-to-end analysis including data visualization of a variety of datasets. This role will have the opportunity to work partially at our campus and remotely. Responsibilities The Bioinformatics Analyst I/II will perform specialized data analysis and build custom data pipelines for quality control and end-to-end analysis of large datasets including: • Implement, apply, and evaluate tools to process, integrate, batch-correct and visualize genomics datasets (single-cell RNA-seq, Bulk RNA-seq, CITE-seq), multiparametric flow cytometry datasets, multiplexed cytokine/protein datasets. • Interpret the data and explain the results in research discussions with experimental collaborators. • Perform quality control and end-to-end analysis of large sequence datasets from diverse workflows. • Identify best-practice bioinformatics tools and strategies to meet the needs of proposed projects. • Provide figures and written sections describing methods and results for manuscripts, presentations, and grant applications. • Ensure integrity and consistency of primary data, track experimental methods and metadata, define standardized analysis pipelines. • Ability to learn new tools and content quickly and independently (although training will be given for specific types of analysis performed in the lab). • Other duties as assigned. Qualifications MINIMUM QUALIFICATIONS: Bioinformatics Analyst I • Bachelor's degree in biology, bioinformatics, biotechnology, bioengineering or related fields (or equivalent experience). • Demonstrated fluency in R and Python 3. • Proficiency with Linux/Unix shell scripting (e.g., bash). • Familiarity with cloud servers or high-performance computing resources. • Experience with bulk and single cell RNA-seq datasets. • Ability to generate and customize visualizations. • Strong organizational skills, including the ability to manage and prioritize multiple competing tasks. • Good communication skills and an interest in learning. • Ability to work independently and in a team. • Scientific curiosity. Bioinformatics Analyst II In addition to the experience and qualifications outlined above: • Master’s degree in bioinformatics, computational biology, genetics, or related field with at least three years' direct experience in computational analysis of large sequence-based molecular data sets. Please include a cover letter with your application detailing your interest in this position. A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists. Bioinformatics Analyst I: The annual base salary range for this position is from $67,716 to $99,236, and pay offered will be based on experience and qualifications. Bioinformatics Analyst II: The annual base salary range for this position is from $76,606 to $114,878, and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance. This position may be eligible for sign on bonus. Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). Our Commitment to Diversity We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to Human Resources at hrops@fredhutch.org or by calling 206-667-4700

We have an exciting opportunity for a candidate who is interested in working at the forefront of the gene editing (CRISPR knock-out, base editing) and gene modulation (CRISPRa, CRISPRi, RNAi) fields. As a Bioinformatics Scientist 1, you will have the opportunity to apply your bioinformatics background, programming skills, and data analytical knowledge to make key contributions in support of a... wide variety of Revvity products and services including screening services, base editing research, whole genome CRISPR/RNAi reagents, and diagnostics reference standards. In this role, you will work closely with scientists, software engineers, product managers, and other bioinformaticians to support and drive cutting edge research products and services. If you are a strong team player, can learn quickly, and love working on challenging problems, then this is the right role for you! Key Responsibilities • Work as part of an Agile development team with the support of fellow bioinformatics scientists to develop, test, document, and support bioinformatics tools (primarily Python with some C# and R) • Support the Agile development process by adding information to work items and providing feedback on new code through pull requests • Curate, analyze, and interpret complex data sets • Collaborate with scientists, product managers, and software engineers to understand and address the complex emerging needs of our scientists and customers • Prepare and occasionally present high quality client facing data packages and reports to internal/external clients Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities of this job at any time. Basic Qualifications: • Bachelor's degree in bioinformatics, computational biology, statistics, physics, computer science or a life/natural sciences discipline • 2 years of experience in bioinformatics using standard tools and common data sources • 1+ year of Python development experience including creating and querying databases (e.g. PostgreSQL) OR • Master's degree in bioinformatics, computational biology, statistics, physics, computer science or a life/natural sciences discipline • 1+ year of Python development experience including creating and querying databases (e.g. PostgreSQL) Preferred Qualifications: • Bioinformatics experience • Experience analyzing and interpreting complex scientific data • Knowledge of version control (e.g. Git) • Fluent in Python and experience in other languages (e.g. R, C#) • Team player - enjoys collaborating with others to achieve shared goals and objectives • Excellent interpersonal and communication skills, both written and verbal • Problem-focused and able to drive tasks to completion • Experience working as part of an Agile development team • Experience with unit testing • Familiarity with cloud development and resources (Azure, AWS); Linux & HPC experience a plus • Some experience handling or processing Next Generation Sequencing (NGS) data Compensation Range: The base salary for this full-time position is $91,500-95,000. The base pay actually offered to the successful candidate will take into account internal equity, work location, and additional factors, including job-related skills, experience, and relevant education or training. Your recruiter can share more about the specific salary range for your preferred location during the hiring process. Please note that base pay is only one part of our total compensation package and is determined within a range. This range allows for the successful candidate to have an opportunity to progress within the position and develop at our company. This base pay range does not take into account bonuses, equity, or other benefits which may be applicable and are dependent on the level and position offered. What do we offer? We provide competitive and comprehensive benefits to our employees. Below are some highlights of our benefits: · Medical, Dental, and Vision Insurance Options · Life and Disability Insurance · Paid Time-Off · Parental Benefits · 401k with Company Match · Employee Stock Purchase Plan Learn more about Revvity’s benefits by visiting our Why Revvity page. #LI-CH1

The Lead Bioinformatics Research Scientist (Clinical Genomics) performs NGS data analysis for pediatric somatic and germline clinical tests, and provides guidance to less experienced team members. Case findings are presented bi-weekly in a group setting before clinical reports are issued by the on-duty molecular pathologist. Clinical genomics testing relies on a strong partnership between the... Departments of Molecular Pathology and Computational Biology; as a primary user of the clinical pipeline, the Lead Bioinformatic Research Scientist works at the intersection of pipeline development and reporting, providing feedback and facilitating improvement requests/user testing in support of ongoing improvement efforts. Job Responsibilities: • Perform validity review and interpretation of genetic sequence variation identified through diagnostic clinical genetic testing; prepare and present findings • Establish/maintain/improve protocols and best practices of clinical tasks • Support activities of the molecular pathology lab relevant to new test and technology development and updates • Lead and participate in the department's developmental projects and interdepartmental team projects; acts as a project manager when required • Mentor junior variant scientists regarding variant calling/interpretation • Recognize and report system performance problems • Follow written standard operating procedures (SOPs), and maintain proficiency and competency standards required for lab accreditation • Perform other duties as assigned to meet the goals and objectives of the department and institution Minimum Education and/or Training: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Minimum Experience: • Minimum Requirement: Bachelor's degree with 10+ years of relevant post-degree work in bioinformatics, biological sciences, chemistry, bioinformatics, or statistics/computer science (with a background in biological sciences) • Experience Exception: Master's degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience • For lead bioinformatics scientists, substantial experience in at least one programming or scripting language and at least one statistical package is preferred. Alternative titles (for example, Clinical Variant Scientist) may otherwise be deemed appropriate. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $125,840 - $238,160 per year for the role of Lead-Bioinformatics Research Scientist. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude

Research Computing at Boston Children’s supports basic, translational, and clinical research by providing researchers with access to digital tools and technologies. Our computing environment consists of high-performance computing clusters, virtual machines, PetaByte-scale high-performance storage and cloud platforms. We work with BCH scientists to develop solutions in support of cutting-edge... research ranging from genomics to epigenetics and transcriptomics, proteomics and metabolomics. The Senior Bioinformatics Data Scientist will work with PhD-level bioinformatics scientists and researchers who have single-cell RNA-seq, single-cell ATAC-seq, spatial transcriptomics, bulk RNA-seq and ChIP-seq data to investigate mouse and human diseases as well as with other pediatric scientists at BCH. The primary responsibilities will be building pipelines for the analysis, integration and sharing of these data. You will analyze, integrate different types of next-generation sequencing data and interpret the results and will have the opportunity to publish high-profile papers with prominent authorship depending on the intellectual contribution. The ideal candidate should have enthusiasm for developing collaborative relationships and a desire to foster the use of bioinformatics data in research studies. Responsibilities include: • Providing computational support services to Boston Children's Hospital scientists and clinicians by applying a wide range of bioinformatics tools, methods and technologies. • With minimal supervision and direction, completing highly complex assignments in the required timeframe; consistently adhering to and Promoting standard operating procedures and best practices; maintaining and upgrading a wide range of Research Computing tools, methods, and technologies, migrating data, documenting changes, and adjusting internal processes; resolving highly complex problems associated with assignments and seeking supervisor assistance when needed. • Routinely leading, co-leading, or participating in complex bioinformatics projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectives; • Training staff and researchers; effectively tailoring presentations; developing, implementing and maintaining knowledge management systems. To qualify you must have: • Minimum of 4-year Bachelor's degree in STEM. A minimum of one year of position-specific experience, which might potentially include experience acquired through MSc or Ph.D. studies. Preference for candidates with a Ph.D. in Bioinformatics, Computational Biology or related. • Extensive knowledge of the use of bioinformatics computations in high-performance computing environments, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation, etc. • Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters. • Ability to resolve a wide range of complex Research Computing assignments in support of biomedical research. Ability to routinely lead complex projects and coordinate project teams; readiness to seek advice and guidance when needed and to operate effectively in collaboration with scientists and clinicians; ability to follow, improve and create technical documentation and standard operating procedures. • Strong publication record. Ability to effectively convey messages through written communication that are tailored to target audience; meeting discussions and one-on-one verbal communications are clear and effective; ability to conduct effective meetings, to present in departmental and hospital forums, and to develop training instructions and manuals. #LI-Remote

Labcorp’s Companion Diagnostic (CDx) development lab in Morrisville, NC is seeking a Bioinformatics Scientist II to support the development of NGS assays for clinical trials and subsequent diagnostic use. The ideal candidate should have experience designing and implementing new analysis pipelines for NGS assays in a regulated environment, possess strong analytical skills, and be a self-motivated... team player. We are looking for a confident, proactive individual capable of taking the initiative and driving to results! This position is Hybrid. Your success will be measured by meeting project goals on-time and within budget, meeting client expectations, and contributing to scientific growth of the CDx team. At Labcorp you will… • Assume responsibility for designing, validating, and implementing new NGS analysis pipelines including software lifecycle (SLC) activities when applicable. • Provide statistical expertise for development projects. • Work in a fast-paced, high throughput environment to meet client driven timelines. • Interact directly with pharma clients and regulatory authorities, including the FDA. • Be responsible for revenue generation by bioinformatic client deliverables. • Participate in business development activities and presentations to win new business. • Support the Quality Management System with good documentation practices and audit internal activities as applicable. • Write SOPs, validation, and analysis reports. Education PhD in Bioinformatics, Computational Biology, Biostatistics, Biology, Biochemistry, or related field. Experience • 5+ years of post-degree bioinformatics experience working on NGS assays is required, including but not limited to RNA-Seq, WGS, WES, or targeted panels. • Full comfort working in a *nix-based, command line environment. Bash or other scripting skills is essential. • 5+ years of scientific programming using Python and R. • Proficiency in statistical analysis methodologies is required. • Demonstrated ability to design, code, and validate analysis pipelines is required. • Experience with WDL, CWL, or other workflow development languages. • Experience with implementing workflows in a cloud environment. • Experience with Jira, Git and Oracle Agile PML strongly preferred. • Experience in IVD product development, including design control, strongly preferred. Competencies • Able to function in a fast-paced, high throughput environment. • Solid organizational skills and independent drive to sustain productivity and meet deadlines. • Strong interpersonal and teamwork skills are essential. • Ability to prioritize workload to effectively handle several projects at any given time. • Quickly and competently train on and perform new and updated analysis methods. • Understand and perform specific tasks that need to be completed on a daily basis. • Identify and offer suggestions for process improvements. • Ability to complete written reports as part of client deliverables. • Attention to detail and ability to work under pressure to generate high quality data analysis. Labcorp is proud to be an Equal Opportunity Employer: As an EOE/AA employer, Labcorp strives for diversity and inclusion in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications of the individual and do not discriminate based upon race, religion, color, national origin, gender (including pregnancy or other medical conditions/needs), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. We encourage all to apply. For more information about how we collect and store your personal data, please see our Privacy Statement

This Direct-Hire position is in the Food and Drug Administration and is located in the Center for Food Safety and Applied Nutrition, Molecular Methods and Subtyping Branch, Office of Regulatory Sciences which develops new methodology or refining existing methods for the rapid detection and discrimination of foodborne pathogens.

The department of Computational Biology is seeking an experienced lead or principal-level bioinformatics research scientist to provide direction and lead the development of pipelines for use in our clinical genomics program. The clinical genomics program at St. Jude Children’s Research Hospital started in 2013 as a pioneer in the use of whole genome sequencing for clinical testing. This position... in the department of Computational Biology will play a key role in continuing our innovation in this space. The ideal candidate brings knowledge of cancer biology and stays abreast of current methods and trends in published literature. By leveraging this knowledge, working in productive collaboration with stakeholders, this role can proactively identify viable opportunities and effective solutions, thereby serving as a catalyst to innovation within the clinical genomics program. This role involves directing the efforts of the multidisciplinary team that performs end-to-end development of bioinformatics pipelines, including evaluation of existing methods, development of annotation and filtering strategies, and validation in accordance with CAP/CLIA requirements. This requires bioinformatics rigor applied in a clinical context where turnaround time limits, workflow considerations, and unique analytical performance criteria apply. Candidates must possess strong communication and interpersonal skills, as the position will engage regularly with pathologists, analysts, bioinformaticians, and engineers within the departments of Pathology and Computational Biology, as well as clinicians and scientists from various departments in the institution. Job Responsibilities: • Design and lead advanced analyses and deliver high-quality results in a timely manner by identifying new technologies and methodologies and recommend for adoption when appropriate. • Coordinate development of novel software tools and infrastructure as scientific and technical advisor, by contributing code and providing scientific guidance to developers. • Conceptualize, initiate, and lead manuscript preparation and submission of benchmarking results, new pipelines, databases, and scientific discoveries where appropriate. • Establish best practices and new protocols for analysis matching skills and expertise, and share protocols with St. Jude investigators through open documentation and hands-on training. • Assist in acquiring funding to support methods evaluation, development, and infrastructure. • Lead and coordinate the development of curriculum to educate the St. Jude community. • Is an independent project leader for large-scale projects and mentors junior staff. • Perform other duties as assigned to meet the goals and objectives of the department and institution. • Maintains regular and predictable attendance. Minimum Education and/or Training: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Minimum Experience: • Minimum Requirement: Bachelor's degree with 13+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 11+ years of relevant post-degree experience (OR) PhD with 8+ years of relevant post-degree experience. • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Lead/Principal Bioinformatics Research Scientist, Clinical Genomics. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude

Company Description Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve... problems, and work collaboratively with a sense of urgency and compassion. Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career. Recognitions Named Science's Top Employer in 2021, 2022, and 2023 Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That's why we were named the No. 1 company to work for in the biopharma industry in Science's Top Employers Survey for two years in a row. A Certified Great Place to Work We believe our company is truly special, and our employees agree. In July 2023, we became Great Place to Work-certified in the U.S. for the third year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma, Best Workplaces in New York, and Best Workplaces for Millennials lists. OverviewThe candidate will be a core member of a computational team developing and applying cutting-edge AI-driven protein engineering methods to design next-generation biotherapeutics, and will work closely with a dynamic and multidisciplinary team conducting associated protein engineering and preclinical analysis experiments. In particular, the role focuses on analysis and modeling of multiple types of data, including next-generation sequencing and peptidomics, collected as part of our diverse biotherapeutic development campaigns. The candidate will have the opportunity to build and use bioinformatics tools and pipelines to extract information from these rich datasets and thereby help guide design and engineering of life-altering innovative biotherapeutic agents. This position can be remote or hybrid in our Research Development Lab in NJ or NH.Responsibilities • Key responsibilities center on deploying, applying, evaluating, and improving bioinformatics tools and pipelines to manage, analyze, and interpret data regarding our biotherapeutic development campaigns, initially focusing on data from next-generation sequencing and peptidomics. Additional responsibilities will include curation and targeted analysis of background 'omics data relevant to our biotherapeutics. • Practical experience with bioinformatics tools and pipelines for analysis of large-scale biological data in general is required. Experience with next-generation sequencing data, particularly pipelining, quality control, alignment, sequence statistics/analyses, and visualizations, is preferred. Pipeline execution and management within cloud-based platforms (e.g., using tools such as docker and nextflow) is beneficial. • Proficiency in Python and relevant scientific and bioinformatics packages is required. Additional helpful proficiencies include use of visualization packages, creation of end-user available tools and web portals, and use of REST APIs to access public datasets. • An MS, or a BS with 1-2 years of experience, in Bioinformatics, Quantitative Biomedical Sciences, Computer Science, Statistics, Mathematics, or a related quantitative discipline Salary RangeInsmed takes into consideration a combination of candidate's education, training, and experience as well as the position's scope and complexity, the discretion and latitude required in the role, and external market and internal value when determining a salary level for potential new employees. The base salary range for this job is from $89,000.00 to $119,267.00 per yearCompensation & Benefits We're committed to investing in every team member's total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including: • Flexible approach to where and how we work, regionally based • Competitive compensation package including bonus • Stock options and RSU awards • Employee Stock Purchase Plan (ESPP) • Flexible Vacation Policy • Generous paid holiday schedule and winter break ADDITIONAL U.S. BENEFITS: • 401(k) plan with company match • Medical, dental, and vision plans • Company-provided Life and Accidental Death & Dismemberment (AD&D) insurance • Company-provided short and long-term disability benefits • Unique offerings of pet, legal, and supplemental life insurance • Flexible spending accounts for medical and dependent care • Accident and Hospital Indemnity insurance • Employee Assistance Program (EAP) • Mental Health on-line digital resource • Well-being reimbursement • Paid leave benefits for new parents • Paid time off to volunteer • On-site, no-cost fitness center at our U.S. headquarters Additional Information Insmed Incorporated is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement. Applications are accepted for 5 calendar days from the date posted or until the position is filled. #LI-JK1 Employment Type: OTHER

We have an exciting opportunity for a candidate who is interested in working at the forefront of the gene editing (CRISPR knock-out, base editing) and gene modulation (CRISPRa, CRISPRi, RNAi) fields. As a Bioinformatics Scientist 1, you will have the opportunity to apply your bioinformatics background, programming skills, and data analytical knowledge to make key contributions in support of a... wide variety of Revvity products and services including screening services, base editing research, whole genome CRISPR/RNAi reagents, and diagnostics reference standards. In this role, you will work closely with scientists, software engineers, product managers, and other bioinformaticians to support and drive cutting edge research products and services. If you are a strong team player, can learn quickly, and love working on challenging problems, then this is the right role for you! Key Responsibilities • Work as part of an Agile development team with the support of fellow bioinformatics scientists to develop, test, document, and support bioinformatics tools (primarily Python with some C# and R) • Support the Agile development process by adding information to work items and providing feedback on new code through pull requests • Curate, analyze, and interpret complex data sets • Collaborate with scientists, product managers, and software engineers to understand and address the complex emerging needs of our scientists and customers • Prepare and occasionally present high quality client facing data packages and reports to internal/external clients Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities of this job at any time. Basic Qualifications: • Bachelor's degree in bioinformatics, computational biology, statistics, physics, computer science or a life/natural sciences discipline • 2 years of experience in bioinformatics using standard tools and common data sources • 1+ year of Python development experience including creating and querying databases (e.g. PostgreSQL) OR • Master's degree in bioinformatics, computational biology, statistics, physics, computer science or a life/natural sciences discipline • 1+ year of Python development experience including creating and querying databases (e.g. PostgreSQL) Preferred Qualifications: • Bioinformatics experience • Experience analyzing and interpreting complex scientific data • Knowledge of version control (e.g. Git) • Fluent in Python and experience in other languages (e.g. R, C#) • Team player - enjoys collaborating with others to achieve shared goals and objectives • Excellent interpersonal and communication skills, both written and verbal • Problem-focused and able to drive tasks to completion • Experience working as part of an Agile development team • Experience with unit testing • Familiarity with cloud development and resources (Azure, AWS); Linux & HPC experience a plus • Some experience handling or processing Next Generation Sequencing (NGS) data Compensation Range: The base salary for this full-time position is $91,500-95,000. The base pay actually offered to the successful candidate will take into account internal equity, work location, and additional factors, including job-related skills, experience, and relevant education or training. Your recruiter can share more about the specific salary range for your preferred location during the hiring process. Please note that base pay is only one part of our total compensation package and is determined within a range. This range allows for the successful candidate to have an opportunity to progress within the position and develop at our company. This base pay range does not take into account bonuses, equity, or other benefits which may be applicable and are dependent on the level and position offered. What do we offer? We provide competitive and comprehensive benefits to our employees. Below are some highlights of our benefits: · Medical, Dental, and Vision Insurance Options · Life and Disability Insurance · Paid Time-Off · Parental Benefits · 401k with Company Match · Employee Stock Purchase Plan Learn more about Revvity’s benefits by visiting our Why Revvity page. #LI-CH1

This Position is Fully Grant Funded School of Medicine... Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations. Bioinformatician II Summary We are looking for a talented and motivated individual to work with teams of Researchers and Scientists providing bioinformatics expertise, consulting, application development, and support as part of the Duke Predictive Modeling Center (PMC), an NHGRI-funded center with the Impact of Genomic Variation on Function (IGVF) Consortium. Work performed • Contribute to the design, development, adaptation, implementation, and testing of neural networks that are used for predictive modeling of genomic data. Work involved with require increased independence of identifying and implementing solutions with some leadership and supervisory activities. (30%) • Train predictive models using machine learning approaches and technologies. This might include not only writing new code but repackaging and documenting existing scripts to make them reusable and easy to maintain. Work will include training increasingly complex models and will require navigating dynamic computing environments. (25%) • Collaborate and consult with researchers individually or in small groups to analyze problems, recommend technology-based solutions, and design computational strategies for a wide range of biological research. Initiate interdisciplinary collaborations with other centers or departments within the Duke PMC and in collaboration with other research teams with the IGVF consortium. (20%) • Recommend new methods, strategies, and improvements to incorporate into existing models. Try latest tools and analysis methods for new non-conventional genomic data (e.g. CRISPR screens), evaluating their fit and gradually incorporating them into existing analysis pipelines. (15%) • Provide training on bioinformatics-related concepts, applications, and tools to researchers across the PMC and relevant teams within the IGVF. Design and participate in hands-on workshops to teach scientists how to use predictive models and associated neural networks so that these resources are accessible to other groups. (10%) Skills • Experience working with high throughput sequencing datasets (e.g. RNA-seq, ChIP-seq, ATAC-seq, etc.). • Strong and demonstrable programming skills in Python, Tensorflow, and/or R. • Experience with independently identifying solutions and ability to investigate and learn new approaches necessary to adapt existing or new models. • Experience with collaborative development environments, including management of shared repositories (github). • Good communication skills; run and deliver results in a clear and precise way. • Familiarity with High Performance Computing clusters (e.g. SLURM, PBS), including computing environments constructed with CPUs and GPUs. • Familiarity with workflow languages (e.g. CWL, WDL). Education Work requires a M.S. in Bioinformatics or the biological sciences with demonstrable computational skills or a M.S. in computer science with a strong interest in biology/genomics. PhD preferred. Experience Strong expertise with programming required. Minimum Qualifications Education Work requires a M.S. in Bioinformatics or the biological sciences with demonstrable computational skills or a M.S. in computer science with a strong interest in biology/genomics. PhD preferred. Experience Work requires at least 2 years of experience in bioinformatics. OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE Experience with web-based bioinformatics tools, public domain biological databases and software tools for sequence, domain and structural analysis. Extensive familiarity with and development of computational tools in biology that use genomic data to generate biological hypotheses. Experience with a procedural language, proficient in Java, Perl, 'C', web design, DNA genome informatics, proteomics informatics, statistics, and computer science. Experience with relational databases and SQL helpful. 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