Bioinformatics Jobs

Why Mayo Clinic Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and... advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic. You’ll thrive in an environment that supports innovation, is committed to ending racism and supporting diversity, equity and inclusion, and provides the resources you need to succeed. Responsibilities Under general supervision and guidance: - The analyst/programmer is responsible for the support of moderately complex software-based systems in the supported areas. - Contributes to the design, development, implementation, and maintenance of custom software, or the installation and maintenance of purchased software systems. - Produces documentation such as systems requirements, designs, and plans as requested by the work unit leadership. - Work will be reviewed for quality, timeliness, and adequacy at predetermined milestones. Qualifications Working towards a PhD in Computer Science or related Informatics field with a GPA of 3.0 or greater.Experience with Java, SQL, and XML. Exemption Status Nonexempt Compensation Detail This position has a predetermined rate of $27.76 per hour. Benefits Eligible No Schedule Full Time Hours/Pay Period 80 Schedule Details Monday - Friday Weekend Schedule N/A International Assignment No Site Description Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. Affirmative Action and Equal Opportunity Employer As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available. Recruiter Stephanie Baird

Research Computing at Boston Children’s supports basic, translational, and clinical research by providing researchers with access to digital tools and technologies. Our computing environment consists of high-performance computing clusters, virtual machines, PetaByte-scale high-performance storage and cloud platforms. We work with BCH scientists to develop solutions in support of cutting-edge... research ranging from genomics to epigenetics and transcriptomics, proteomics and metabolomics. The Senior Bioinformatics Data Scientist will work with PhD-level bioinformatics scientists and researchers who have single-cell RNA-seq, single-cell ATAC-seq, spatial transcriptomics, bulk RNA-seq and ChIP-seq data to investigate mouse and human diseases as well as with other pediatric scientists at BCH. The primary responsibilities will be building pipelines for the analysis, integration and sharing of these data. You will analyze, integrate different types of next-generation sequencing data and interpret the results and will have the opportunity to publish high-profile papers with prominent authorship depending on the intellectual contribution. The ideal candidate should have enthusiasm for developing collaborative relationships and a desire to foster the use of bioinformatics data in research studies. Responsibilities include: • Providing computational support services to Boston Children's Hospital scientists and clinicians by applying a wide range of bioinformatics tools, methods and technologies. • With minimal supervision and direction, completing highly complex assignments in the required timeframe; consistently adhering to and Promoting standard operating procedures and best practices; maintaining and upgrading a wide range of Research Computing tools, methods, and technologies, migrating data, documenting changes, and adjusting internal processes; resolving highly complex problems associated with assignments and seeking supervisor assistance when needed. • Routinely leading, co-leading, or participating in complex bioinformatics projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectives; • Training staff and researchers; effectively tailoring presentations; developing, implementing and maintaining knowledge management systems. To qualify you must have: • Minimum of 4-year Bachelor's degree in STEM. A minimum of one year of position-specific experience, which might potentially include experience acquired through MSc or Ph.D. studies. Preference for candidates with a Ph.D. in Bioinformatics, Computational Biology or related. • Extensive knowledge of the use of bioinformatics computations in high-performance computing environments, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation, etc. • Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters. • Ability to resolve a wide range of complex Research Computing assignments in support of biomedical research. Ability to routinely lead complex projects and coordinate project teams; readiness to seek advice and guidance when needed and to operate effectively in collaboration with scientists and clinicians; ability to follow, improve and create technical documentation and standard operating procedures. • Strong publication record. Ability to effectively convey messages through written communication that are tailored to target audience; meeting discussions and one-on-one verbal communications are clear and effective; ability to conduct effective meetings, to present in departmental and hospital forums, and to develop training instructions and manuals. #LI-Remote

SHIFT: Day (United States of America ... Seeking Breakthrough Makers Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation. At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career. CHOP’s Commitment to Diversity, Equity, and Inclusion CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children. We strongly encourage all candidates of diverse backgrounds and lived experiences to apply. A Brief Overview The Bioinformatics Scientist III position is an intermediate level position for a PhD level professional and a final stage position for those with high experience without a PhD. The focus of the position is collaboration-level application of bioinformatics tools and methods to bench and clinical research problems in various biomedical domains. The position allows for a wide variety of activities described within the job responsibilities and encompasses positions within both research and clinical environments. Activities occur with a low degree of supervision with expectation for highly independent judgment, development of bioinformatics workflows and processes, and presentation of results. The Bioinformatics Scientist III will apply best practices in collaborative science as a bioinformatics domain scientific collaborator. Academic output is a focus of this position and is expected with a low degree of supervision. The Bioinformatics Scientist III is primarily focused on taking a lead, proactive scientific role in teams and projects as a bioinformatics domain expert. The Bioinformatics Scientist III must be able to perform all responsibilities listed in the Bioinformatics Scientist II job description. All responsibilities listed in this description are additional. What you will do • Pre-Analysis (10%): Actively participate in the development of application portfolio by developing knowledge of internally developed systems, open-source programs, and commercial applications. Provide efficient data management support. • Lead development of additional pipeline functionality and changes by providing knowledge of both collaboration-specific requirements and bioinformatics discipline advances • Coding (10%): Code and generally support code and applications on behalf of collaborative project and/or team. • Master best practices for project-based code development, QC, and execution consist with the expectations of specific collaborations • Lead peer-to-peer code reviews by participating in informal and formal critical code reviews • Data Analysis (30%): Analyze data of high complexity by applying sound statistical and commonly accepted bioinformatics methods to -omics data primarily under the direction of the collaborative project team • Lead regular peer-to-peer review of analysis plans in both informal and formal settings • Develop multiple specialty analytical areas that serve one or more collaborative teams • Lead adoption of best practices in specialty analytical or biomedical areas by the bioinformatics group and peers • Collaboration (30%): Lead bioinformatics portion of scientific collaborations as the primary bioinformatics resource • As bioinformatics point, assume management role for projects of low-to-moderate complexity, including all aspects of timelines, risk identification and mitigation strategies, and communication mechanisms • Directly manage all elements of project satisfaction and performance relative to scientific project aims • Promote continual objective, hard discussions about overall health of project and relationship • Develop new collaborations with moderate degree of supervision • Academic Output (20%): Lead project-based presentations, grant sections, and manuscript sections with subsequent review by peers and mentors • Regularly coordinate and write bioinformatics-focused manuscripts and publications • Regularly coordinate and lead podium presentations and posters • Proactively contribute to entire bioinformatics and other sections of grant and award proposals Education Qualifications • Master's Degree Required • Doctorate biological or computational discipline Preferred Experience Qualifications • At least five (5) years experience in applied bioinformatics, genomics, and computational work. This experience can be inclusive of a relevant PhD dissertation. Required Skills and Abilities • Ability to, under supervision, conceive of, plan, implement, validate, and disseminate entire research projects is required. • Ability to assume principal investigator or similar role in academic research is preferred. • Strong UNIX/LINUX expertise required. • Proficiency in R or similar commonly used bioinformatics language required • Experience with Python, Perl, or other languages required. • Experience with pipeline or workflow development frameworks preferred. • Experience with management and analysis of complex data types required. • Proficiency in various open source and commercial bioinformatics resources and software required. • Experience with genomic/proteomic data analysis methods required. • Experience or knowledge of technologies commonly used in biological labs, such as PCR, cloning, electrophoresis gels, and cell culture required. • Knowledge of the working mechanism of microarray, NGS, mass spectrometry, or other high-throughput technologies and awareness of their strengths and weaknesses, as well as applicability to a specific biological problem is required. • Familiarity with resources of genomic data sets and analysis tools, such as UCSC Genome Browser, Bioconductor, ENCODE, and NCBI databases is required. • Ability to correctly select and perform statistical tests for most types of genomic data, and to properly interpret their results in the scenario of a specific study is required. • Ability to leverage unique knowledge of bioinformatics, applied biostatistics, molecular biology, and measurement platforms for effective scientific discussion with biologists and clinicians is required. • Ability to determine most favorable academic output as a primary research outcome is preferred. • Ability to objectively critique results and present as valid or questionable, taking into account all aspects of study design, technical issues, and limitations of workflows is required. • Accountability and attention to timelines. • Excellent organization and communication skills with an emphasis on strong presentation skills • Ability to independently plan and execute analyses of moderate complexity required • Ability to provide objective validation of results required • Ability to work in a team environment. To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine. Learn more. Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed. EEO / VEVRAA Federal Contractor | Tobacco Statement

Overview We are looking for a candidate to lead a team of bioinformatics scientists and developers that supports the Institute for Genomic Medicine’s (IGM) efforts to become leader in pediatric genomics and precision medicine. This individual will manage technical resources, directing day-to-day operations of the Bioinformatics Research and Development team, overseeing multiple projects and... reporting to leadership on progress. This is a diverse, fast-paced and team-oriented environment integrating pediatric genetics and genomics, laboratory science, bioinformatics, and clinical process data. It is expected that the individual in this position will possess strong leadership and software development abilities, enjoys solving complex problems, and has a desire to make an impact in medical research and patient care. Why Nationwide Children's Hospital? The moment you walk through our doors, you feel it. When you meet our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it. Welcome to Nationwide Children’s Hospital, Where Passion Meets Purpose. Here, Diversity, Equity and Inclusion are integrated into our core values and practices. We are passionate about building, sustaining and evolving an inclusive and equitable environment. We are seeking individuals who live these values and want to share their experiences and efforts in support of our collective mission. We’re 14,000 strong. And it takes every one of us to improve the lives of the kids we care for, and the kids around the world we’ll never meet. Kids who live healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children’s Hospital. A Place to Be Proud. Responsibilities • Manage the day-to-day operations of the Bioinformatics Research and Development team, delivering quality work on-time, within budget and scope • Support the analytical, collaborative, and development needs of research and clinical faculty and staff. • Develop and deploy robust, novel computational approaches to data analysis for a variety of NGS protocols and related methods. • Implement and maintain best practices in coding, including code review and change/release management processes. • Develop methods to automate processing and analysis of large data sets. • Lead the utilization of advanced statistical, data mining, and machine learning approaches to identify and visualize new genomic discoveries. • Participate in the experimental design, requirement gathering, and analysis for a variety of research projects and collaborations. • Author journal publications, present at professional meetings, and help prepare grant applications. Qualifications Education and Experience • Master’s degree or higher in Bioinformatics, Computer Science, Biological Sciences or related discipline. • 7+ years of computational experience, with 3+ years leading team members, products, and/or projects. Knowledge, Skills, and Abilities • Experience managing, supervising, or mentoring bioinformatics and/or computational staff. • Proven success in the design, development, and deployment of data analysis pipelines, including demonstrated expertise in software life cycle and development methodologies. • Exceptionally deep computational understanding, strong programming skills, and experience with a range of statistical tests and experimental design techniques. • Experience with Unix/Linux systems, cloud computing, containers, and automation. • Proficiency with modern NGS tools and analysis of NGS data. • Strong people and management skills to interact and collaborate with staff, colleagues, and third parties. • Ability to communicate technical details in clear and understandable business language. • Capable of managing multiple projects in a fast-paced environment. • Demonstrated ability to learn new technology quickly. Minimum Physical Requirements: Must be able to remain in stationary position for extended periods of time. Must be able to repeatedly operate a computer and other office productivity machinery, such as a calculator, copy machine, and computer printer. Must be able to occasionally move about inside the workspace to access objects necessary for the job (file cabinets, printers, etc.). Must be able to accurately communicate information and ideas in person and through telecommunications. EOE M/F/Disability/Vet

Company Description Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve... problems, and work collaboratively with a sense of urgency and compassion. Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career. Recognitions Named Science’s Top Employer in 2021, 2022, and 2023 Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That’s why we were named the No. 1 company to work for in the biopharma industry in Science’s Top Employers Survey for two years in a row. A Certified Great Place to Work We believe our company is truly special, and our employees agree. In July 2023, we became Great Place to Work-certified in the U.S. for the third year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma™, Best Workplaces in New York™, and Best Workplaces for Millennials™ lists. Overview The candidate will be a core member of a computational team developing and applying cutting-edge AI-driven protein engineering methods to design next-generation biotherapeutics, and will work closely with a dynamic and multidisciplinary team conducting associated protein engineering and preclinical analysis experiments. In particular, the role focuses on analysis and modeling of multiple types of data, including next-generation sequencing and peptidomics, collected as part of our diverse biotherapeutic development campaigns. The candidate will have the opportunity to build and use bioinformatics tools and pipelines to extract information from these rich datasets and thereby help guide design and engineering of life-altering innovative biotherapeutic agents. This position can be remote or hybrid in our Research Development Lab in NJ or NH. Responsibilities • Key responsibilities center on deploying, applying, evaluating, and improving bioinformatics tools and pipelines to manage, analyze, and interpret data regarding our biotherapeutic development campaigns, initially focusing on data from next-generation sequencing and peptidomics. Additional responsibilities will include curation and targeted analysis of background ‘omics data relevant to our biotherapeutics. • Practical experience with bioinformatics tools and pipelines for analysis of large-scale biological data in general is required. Experience with next-generation sequencing data, particularly pipelining, quality control, alignment, sequence statistics/analyses, and visualizations, is preferred. Pipeline execution and management within cloud-based platforms (e.g., using tools such as docker and nextflow) is beneficial. • Proficiency in Python and relevant scientific and bioinformatics packages is required. Additional helpful proficiencies include use of visualization packages, creation of end-user available tools and web portals, and use of REST APIs to access public datasets. • An MS, or a BS with 1-2 years of experience, in Bioinformatics, Quantitative Biomedical Sciences, Computer Science, Statistics, Mathematics, or a related quantitative discipline Salary Range Insmed takes into consideration a combination of candidate’s education, training, and experience as well as the position’s scope and complexity, the discretion and latitude required in the role, and external market and internal value when determining a salary level for potential new employees. The base salary range for this job is from $89,000.00 to $119,267.00 per year Compensation & Benefits We’re committed to investing in every team member’s total well-being, now and in the future. We offer a competitive total-rewards package to all employees around the world, including: • Flexible approach to where and how we work, regionally based • Competitive compensation package including bonus • Stock options and RSU awards • Employee Stock Purchase Plan (ESPP) • Flexible Vacation Policy • Generous paid holiday schedule and winter break ADDITIONAL U.S. BENEFITS: • 401(k) plan with company match • Medical, dental, and vision plans • Company-provided Life and Accidental Death & Dismemberment (AD&D) insurance • Company-provided short and long-term disability benefits • Unique offerings of pet, legal, and supplemental life insurance • Flexible spending accounts for medical and dependent care • Accident and Hospital Indemnity insurance • Employee Assistance Program (EAP) • Mental Health on-line digital resource • Well-being reimbursement • Paid leave benefits for new parents • Paid time off to volunteer • On-site, no-cost fitness center at our U.S. headquarters Additional Information Insmed Incorporated is an Equal Opportunity/Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement. Applications are accepted for 5 calendar days from the date posted or until the position is filled. #LI-JK1

Bioinformatics/Biostatistics Entry Professional - 33915 University Staff Description... University of Colorado Anschutz Medical Campus School of Medicine | Department of Medicine | Division of Rheumatology Job Title: Bioinformatics/Biostatistics Entry Professional Position: # 00824005 – Requisition: # 33915 Job Summary: Entry Information Science Professionals utilize applied or computational mathematical analyses for a wide array of different applications and to solve complex problems. Experiments may include text interpretation, coding, ground theory methodology for the analysis of certain data, and quantum state analyses. Entry Information Science Professionals may also perform duties in labs that use primarily electronic equipment. This Information Sciences Professional will join a growing multi-disciplinary team working at the intersection of epidemiology, biostatistics, multi-omic data analysis, and rheumatology. Half of this position will be devoted to the NIH-funded research program of Jill Norris, using integrative analyses of high-dimensional multi-omics to provide insight into the development and progression of rheumatoid arthritis. The other half of this position will consist of providing bioinformatic and biostatistical support to researchers within the Division of Rheumatology who perform translational research on autoimmune and inflammatory diseases. Key Responsibilities: • Collaborate with and support Principal Investigators (PI) and other stakeholders in the area of bioinformatics and data analysis. • Perform scientifically rigorous data management and bioinformatic analyses. • Develop and implement complex analyses pipelines, programming, and data visualization techniques for multi-layered -omics datasets (transcriptome, epigenome, proteome, microbiome, etc.). • Creatively and effectively integrate data from multiple sources to accelerate discoveries. • Assist with the design and development of major bioinformatics-related programming projects. • Write custom scripts to access databases and analyze data. • Perform biostatistical/data science tasks for data management, data analysis and manuscript preparation to assist all levels of biomedical investigators and clinicians on new research activities across a wide range of disciplines. • Provide basic biostatistical and data science advice to PIs and other stakeholders. • Assist in the design and conduct of new studies. • Perform data cleaning and association testing. • Process, map, and perform QC on newly collected raw sequencing data files (e.g. single-cell RNA-seq, microbial shotgun metagenomic sequencing, ATAC-seq). • Assist in development of new analytical pipelines and maintain existing workflows. • Assist in disseminating findings through preparation of abstracts, oral and poster presentations, and scientific manuscripts. Work Location: Hybrid – this role is eligible for a hybrid schedule of 3 days per week on campus and as needed for in-person meetings. Why Join Us: The Division of Rheumatology is a national leader in innovative research, medical education, and excellent patient care. This position is a critical and valued team member that assists the division in advancing their work. This Information Sciences Professional will join a growing multi-disciplinary team working at the intersection of epidemiology, biostatistics, multi-omic data analysis, and rheumatology. The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off – vacation, sick, holidays and more. To see what benefits are available, please visit: https://apptrkr.com/get_redirect.php?id=5331235&targetURL=00824005 – Requisition: # 33915 Job Summary: Entry Information Science Professionals utilize applied or computational mathematical analyses for a wide array of different applications and to solve complex problems. Experiments may include text interpretation, coding, ground theory methodology for the analysis of certain data, and quantum state analyses. Entry Information Science Professionals may also perform duties in labs that use primarily electronic equipment. This Information Sciences Professional will join a growing multi-disciplinary team working at the intersection of epidemiology, biostatistics, multi-omic data analysis, and rheumatology. Half of this position will be devoted to the NIH-funded research program of Jill Norris, using integrative analyses of high-dimensional multi-omics to provide insight into the development and progression of rheumatoid arthritis. The other half of this position will consist of providing bioinformatic and biostatistical support to researchers within the Division of Rheumatology who perform translational research on autoimmune and inflammatory diseases. Key Responsibilities: • Collaborate with and support Principal Investigators (PI) and other stakeholders in the area of bioinformatics and data analysis. • Perform scientifically rigorous data management and bioinformatic analyses. • Develop and implement complex analyses pipelines, programming, and data visualization techniques for multi-layered -omics datasets (transcriptome, epigenome, proteome, microbiome, etc.). • Creatively and effectively integrate data from multiple sources to accelerate discoveries. • Assist with the design and development of major bioinformatics-related programming projects. • Write custom scripts to access databases and analyze data. • Perform biostatistical/data science tasks for data management, data analysis and manuscript preparation to assist all levels of biomedical investigators and clinicians on new research activities across a wide range of disciplines. • Provide basic biostatistical and data science advice to PIs and other stakeholders. • Assist in the design and conduct of new studies. • Perform data cleaning and association testing. • Process, map, and perform QC on newly collected raw sequencing data files (e.g. single-cell RNA-seq, microbial shotgun metagenomic sequencing, ATAC-seq). • Assist in development of new analytical pipelines and maintain existing workflows. • Assist in disseminating findings through preparation of abstracts, oral and poster presentations, and scientific manuscripts. Work Location: Hybrid – this role is eligible for a hybrid schedule of 3 days per week on campus and as needed for in-person meetings. Why Join Us: The Division of Rheumatology is a national leader in innovative research, medical education, and excellent patient care. This position is a critical and valued team member that assists the division in advancing their work. This Information Sciences Professional will join a growing multi-disciplinary team working at the intersection of epidemiology, biostatistics, multi-omic data analysis, and rheumatology. The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off – vacation, sick, holidays and more. To see what benefits are available, please visit: https://apptrkr.com/get_redirect.php?id=5331235&targetURL=33915 Job Summary: Entry Information Science Professionals utilize applied or computational mathematical analyses for a wide array of different applications and to solve complex problems. Experiments may include text interpretation, coding, ground theory methodology for the analysis of certain data, and quantum state analyses. Entry Information Science Professionals may also perform duties in labs that use primarily electronic equipment. This Information Sciences Professional will join a growing multi-disciplinary team working at the intersection of epidemiology, biostatistics, multi-omic data analysis, and rheumatology. Half of this position will be devoted to the NIH-funded research program of Jill Norris, using integrative analyses of high-dimensional multi-omics to provide insight into the development and progression of rheumatoid arthritis. The other half of this position will consist of providing bioinformatic and biostatistical support to researchers within the Division of Rheumatology who perform translational research on autoimmune and inflammatory diseases. Key Responsibilities: • Collaborate with and support Principal Investigators (PI) and other stakeholders in the area of bioinformatics and data analysis. • Perform scientifically rigorous data management and bioinformatic analyses. • Develop and implement complex analyses pipelines, programming, and data visualization techniques for multi-layered -omics datasets (transcriptome, epigenome, proteome, microbiome, etc.). • Creatively and effectively integrate data from multiple sources to accelerate discoveries. • Assist with the design and development of major bioinformatics-related programming projects. • Write custom scripts to access databases and analyze data. • Perform biostatistical/data science tasks for data management, data analysis and manuscript preparation to assist all levels of biomedical investigators and clinicians on new research activities across a wide range of disciplines. • Provide basic biostatistical and data science advice to PIs and other stakeholders. • Assist in the design and conduct of new studies. • Perform data cleaning and association testing. • Process, map, and perform QC on newly collected raw sequencing data files (e.g. single-cell RNA-seq, microbial shotgun metagenomic sequencing, ATAC-seq). • Assist in development of new analytical pipelines and maintain existing workflows. • Assist in disseminating findings through preparation of abstracts, oral and poster presentations, and scientific manuscripts. Work Location: Hybrid – this role is eligible for a hybrid schedule of 3 days per week on campus and as needed for in-person meetings. Why Join Us: The Division of Rheumatology is a national leader in innovative research, medical education, and excellent patient care. This position is a critical and valued team member that assists the division in advancing their work. This Information Sciences Professional will join a growing multi-disciplinary team working at the intersection of epidemiology, biostatistics, multi-omic data analysis, and rheumatology. The University of Colorado offers a comprehensive benefits package that includes health insurance, life insurance, retirement plans, tuition benefits, ECO pass, paid time off – vacation, sick, holidays and more. To see what benefits are available, please visit: https://www.cu.edu/employee-services/benefits-wellness. Diversity and Equity: The University of Colorado Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty, and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities, persons within the LGBTQ+ community and all veterans. The University of Colorado is committed to diversity and equality in education and employment. Qualifications: Minimum Qualifications: • Bachelor's degree in Bioinformatics, Biostatistics, Computational Biology, Data Science, Computer Science or related field. • A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis. Applicants must meet minimum qualifications at the time of hire. Preferred Qualifications: • Master's degree in Bioinformatics, Biostatistics, Computational Biology, Data Science, Computer Science or related field. • Experiences analyzing data using high-performance or cloud-based computing. Knowledge, Skills, and Abilities: • Strong knowledge of basic statistical principles relevant in medical research. • Ability to analyze and solve complex problems and apply quantitative analytical approaches. • Demonstrated fluency in one or more programming languages (e.g., R, Python, Perl, Java, C++) and willingness to learn new programming languages as necessary. • Familiarity with statistical analytical concepts and methods. • Ability to communicate effectively, both in writing and orally. • Ability to establish and maintain effective working relationships with employees at all levels throughout the institution. • Outstanding customer service skills. • Demonstrated commitment and leadership ability to advance diversity and inclusion. How to Apply: For full consideration, please submit the following document(s): 1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position. 2. Curriculum vitae / Resume 3. Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address. Questions should be directed to: Helena Jonsson, annahelena.jonsson@cuanschutz.edu Screening of Applications Begins: Immediately and continues until June 18th, 2024. Anticipated Pay Range: The starting salary range (or hiring range) for this position has been established as $50,864 – $64,699. The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level. Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line. Total Compensation Calculator: http://www.cu.edu/node/153125 ADA Statement: The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu​. Background Check Statement: The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students, and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees. Vaccination Statement: CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program. Qualifications Application Materials Required: Cover Letter, Resume/CV, List of References Job Category: Research Services Primary Location: Hybrid Department: U0001 -- Anschutz Med Campus or Denver - 20229 - SOM-MED-RHEUM GENRL OPERATIONS Schedule: Full-time Posting Date: Jun 13, 2024 Unposting Date: Jun 19, 2024, 5:59:00 AM Posting Contact Name: Helena Jonsson Posting Contact Email: annahelena.jonsson@cuanschutz.edu Position Number: 00824005 jeid-c111ee4352f17947bad7184c4eea5fb1

The Bioinformatics Research Scientist is responsible for designing, developing, improving, modifying, and operating data analysis pipelines. Manages projects and coordinates other efforts related to analysis and infrastructure as directed. Job Responsibilities... • Independently perform basic and advanced level statistical analysis, algorithm implementation, programming from a variety of biotechnology platforms, and oversee quality check. • Design and prepare materials and courses for training on various bioinformatics software and databases, computing, data mining, and analysis. • Act as a liaison between end-users, software developers, system designers, and different departments. • Establish protocols or best practices for common research tasks and SOP, evaluate products and solutions to make recommendations, and integrate solutions. • Lead the development, implementation, installation, and maintenance of databases; coordinate data collection, database implementation, and usage and any hardware and software related to database collection. • Develop programs to assist in the analysis of data within the databases. • Assist in planning, coordinating, and organizing projects across departments and delegate tasks based on priority, expertise, and capacity. • Perform other duties as assigned to meet the goals and objectives of the department and institution. • Maintains regular and predictable attendance. Minimum Education and/or Training: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Minimum Experience: • Minimum Requirement: Bachelor's degree with 6+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 4+ years of relevant post-degree experience (OR) PhD with no experience. • Experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86,320 - $154,960 per year for the role of Bioinformatics Research Scientist. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude

Job Description Make a difference every single day... At Cedars-Sinai, we're motivated by a collective spirit of innovation and the challenge to continuously improve. Above all, we share a real passion for helping others. Day after day, from department to department, our people give their all to create a community unlike any other. This is just one of the many reasons U.S. News & World Report has named us one of America’s Best Hospitals—and now we invite you to join us and make a difference every single day in service of this outstanding work – excellence and innovation in patient care, research, and community service. From working with a team of dedicated professionals to using state-of-the-art facilities, you’ll have great resources to do something incredible—for yourself, and for others. What will you be doing in this role? The Clinical Bioinformatician works under the strategic guidance of the Division Director. Develops and maintains bioinformatics tools and pipelines, contributing to the enhancement of genomic data analysis and interpretation. The Clinical Bioinformatician aids in the division's quality management program and strives for operational excellence. Working alongside faculty and the operations team, contributes to aligning bioinformatics efforts with the division's goals, meeting both immediate needs and long-term objectives. The Clinical Bioinformatician is committed to patient care, applying bioinformatics practices with an understanding of the patient population's needs to positively impact clinical outcomes. #Jobs-Indeed Primary Duties and Responsibilities: • Performs data analyses for clinical genomics testing, including quality control functions consistent with the Division's Quality Management Plan. • Designs, develops, implements, and maintains bioinformatics analysis pipelines for clinical genomics service, including NGS. Designs, develops, implements, and maintains tools for data mining and quality control of clinical genomic testing in accordance with the Division's Quality Management Plan. • Collaborates effectively with faculty, variant scientists, and laboratory operations teams to support the efficient delivery of clinical services. • In collaboration with faculty and operational leadership, effectively adjusts priorities according to the workload and to meet the needs of the Division. • Aligns to business and/or operations plans, contributes to process improvement, and participates in design and implementation of new testing. • Keeps abreast of the latest developments in bioinformatics, computational biology, and clinical genomics to assist in identifying, evaluating, and incorporating relevant algorithms and software. Qualifications Requirements: • Bachelor's Degree in Bioinformatics, computational biology, or related field. • Doctorate Degree in Cancer genetics, human genetics or applicable biological science is preferred. • One (1) year of experience in developing, implementing, and maintaining NGS pipelines. Familiarity with common amplicon-based and/or hybrid capture sequencing bioinformatics. • Three (3) years of experience in developing, implementing, and maintaining NGS pipelines in a clinical setting is preferred. Req ID : 2857 Working Title : Clinical Bioinformatician, Molecular Pathology Department : Molecular Pathology Business Entity : Cedars-Sinai Medical Center Job Category : Clinical Operations Job Specialty : Clinical Operations Overtime Status : EXEMPT Primary Shift : Day Shift Duration : 8 hour Base Pay : $89,086.40 - $142,542.40

Overview Join the HJF Team... HJF is seeking a Bioinformatics Scientist to support research at the Bioinformatics High Computing Software Applications Institute (BHSAI) in Frederick, MD. The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a nonprofit organization dedicated to advancing military medicine. We serve military, medical, academic and government clients by administering, managing and saupporting preeminent scientific programs that benefit members of the armed forces and civilians alike. Since its founding in 1983, HJF has served as a vital link between the military medical community and its federal and private partners. HJF's support and administrative capabilities allow military medical researchers and clinicians to maintain their scientific focus and accomplish their research goals. Responsibilities • Conduct research using bioinformatics theory and methods in areas such as pharmaceuticals, medical technology, biotechnology, computational biology, proteomics, computer information science, biology and medical informatics. • May design databases and develop algorithms for processing and analyzing genomic information, or other biological information. • May perform other duties and responsibilities as assigned or directed by the supervisor. This may include attendance of and participation in required training for role. Qualifications Education and Experience • Master's Degree in Computer Engineering, Computer Science, Information Technology, or related fields is required. • At least 1 year of experience in occupations of Bioinformatics Data Architect, Software Developer, Computer Systems Analyst, Programmer Analyst, Bioinformaticist, Research Associate, Research Scientist, Scientific Database Curator, Bioinformatics Technician, Biostatistician, Data Scientist, or related. Required Knowledge, Skills and Abilities • Work experience with RDKit, MarvinJS, Chemaxon Postgres Cartridge, Visual Studio, Knime Workflow Editor, Python and Docker. Work Environment • This position will take place primarily in an office setting. We offer competitive salaries and benefits. Travel may be required. Please apply online at hjf.org/careers Job No: 2024-4466 or email resumes to careers@hjf.org referencing the job number in the subject line. Some HJF employees are required to be fully vaccinated against COVID-19. Proof of vaccination or an approved religious or medical accommodation will be required. Employment with HJF is contingent upon successful completion of a background check, which may include, but is not limited to, contacting your professional references, verification of previous employment, education and credentials, a criminal background check, and a department of motor vehicle (DMV) check if applicable. Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Chief Human Resources Officer. Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information. 41 CFR 60-1.35(c) Any qualifications to be considered as equivalents, in lieu of stated minimums, require the prior approval of the Chief Human Resources Officer

Full-time experimental postdoctoral fellow positions are available in Professor Yiwen Chen's lab. Dr. Chen's lab focuses on deciphering the cell signaling, epigenetic/epitranscriptomic and RNA-based regulation mechanism of cancer immunology in solid tumors, neural stem cells and cancer stem cells of brain tumor. The Chen lab has great expertise in combining computational with high-throughput... approaches such as single-cell multi-omics profiling (e.g., scRNA-seq and Perturb-seq), CRISPR/Cas9, mass spectrometry, ChIP-seq, RNA immunoprecipitation (RIP)-seq, eCLIP-seq (enhanced CrossLinking and Immunoprecipitation followed by high-throughput sequencing) and Ribosome Profiling (Ribo-seq), to decipher cryptic translation of the non-canonical open reading frames (ORFs) and/or noncoding RNA (ncRNA)/RNA-binding protein (RBP)-mediated regulatory circuitries. The experimental postdocs will leverage the high-throughput assays developed/established in the lab to study the cell signaling, epigenetic/epitranscriptomic and RNA-based regulation that is important for tumor immunity in solid tumors, neural stem cells and cancer stem cells of brain tumors, as well as develop T cell-based and/or combinatorial cancer immune therapies. The former postdoctoral trainees from the Chen lab have excelled in both academia and industry, including 4 past/current postdoctoral trainees from Chen lab who are/will become a faculty in U.S. or China. Chen lab representative publications include: Nature Structural & Molecular Biology (2023, PMC10716047), Science (2023, PMID: 37676964), Science Advances (2023, PMC10403220), The Journal of Clinical Investigation (2023, PMC9974104), Journal of Experimental Medicine (2021, PMC7543092), Genome Biology (2021, PMC8381491), The Journal for ImmunoTherapy of Cancer (2021, PMC7887353), Nature Methods (2018, PMC5967874), Nature Genetics (2017, PMID: 27841882), Nature Communications (2017, PMC5701008), and Trends in Genetics (2016, PMC4805481). LEARNING OBJECTIVES The postdoctoral trainee will learn how to conduct highly interdisciplinary research at the interface of computational/functional genomics, RNA biology, cancer biology, cancer immunology and neural stem biology. He/she will also learn how to perform translational research in collaboration with basic scientists and physicians. ELIGIBILITY REQUIREMENTS Applicants should have a Ph.D. degree (or equivalent) in biomedical sciences. Strong background in one or more of the following areas: molecular biology; protein/RNA biochemistry; transcriptional/epigenetic regulation; cell signaling; virology; immunology; T-cell biology; cancer biology. Mouse model experience and bioinformatics/genomics/proteomics expertise are not required, but highly desirable. All applicants should have good spoken and written communication skills. ADDITIONAL APPLICATION INFORMATION Interested applicants should send i) a cover letter briefly describing your previous experience and your future research interest/plan, ii) a curriculum vitae, and iii) contact information of at least three references to Dr. Yiwen Chen (ychen26@mdanderson.org). POSITION INFORMATION MD Anderson follows the NIH stipend levels as outlined by the Kirchstein - NRSA. This full-time trainee position will provide a salary between $56,484 to $68,604, dependent upon the years of postgraduate experience. MD Anderson offers compensated trainees: - Paid medical benefits (zero premium) starting on first day for trainees who work 30 or more hours per week - Group Dental, Vision, Life, AD&D and Disability coverage - Paid Education Vacation and Sick Leave - Paid institutional holidays, wellness leave, childcare leave and other paid leave programs - Teachers Retirement System defined-benefit pension plan and two voluntary retirement plans - Employer paid life, AD&D and an illness-related reduced salary pay program - Health Savings Account and Dependent Care Reimbursement flexible spending accounts - Fertility benefits - State of Texas longevity pay - Extensive wellness, fitness, employee health programs and employee resource groups