Bioinformatics Jobs

The Position The Position... Genentech is inviting applications for a Computational Biologist to join the Department of Human Genetics as a Senior Scientist. Genentech has access to vast, and growing, repositories of genetic, genomic and clinical data, gathered from internal studies (including many of our trials), as well as collaborative and public external data sets. The Senior Scientist appointed to this position will play a pivotal role in developing and implementing analytical strategies that allow us to better integrate and interpret these data, delivering biological insights into disease pathophysiology that propel our translational goals, most obviously through the identification of novel therapeutic targets and biomarkers involved in disease onset and/or disease progression. • We are keen to attract candidates with skills and experience that position them to tackle key challenges in multimodal data integration as it relates to human biology. What strategies should we adopt for the effective and insightful integration of multimodal data at scale to deliver causal inference regarding disease pathogenesis? How can we do a better job of connecting the genetic signals that come from GWAS to the genes, pathways and processes through which they exert their effects on disease biology and outcomes? How can we optimize our capacity to integrate a diversity of data types, relevant to efficacy, safety and druggability, to prioritize the most promising targets for a given disease? To be successful, the person we seek will need to have a broad range of skills and expertise that embraces association analysis in genotype and sequence data, strong competence in the analysis of sequence-based molecular assay data (eg RNA-Seq), familiarity with approaches for the integration of genetic and molecular data, and a profound understanding of causal inference. They are also likely to be proficient in the use of high performance computing resources, and to have experience of implementing a range of AI/ML approaches. As well as developing and implementing a transformational research program in these areas, working closely with colleagues and mentors in human genetics, the appointee will be responsible for: • Extensive collaboration with colleagues across “Translational Genomics” who are responsible for the generation and analysis of data arising from our capabilities in molecular profiling, spatial analysis and perturbation assays • Extensive collaboration with colleagues in Neuroscience (and other Therapeutic Areas) who will take the biological insights generated and turn them into actionable hypotheses and lead molecules • Design and execution of targeted analyses to uncover novel therapeutic targets and biomarkers of disease heterogeneity, progression, and treatment response • Maintaining an excellent publication record • Presentation and communication of findings in cross-functional teams • Initiation of and participation in strategic external collaborations in pursuit of these goals. Genentech is committed to the development and delivery of precision medicines, which take individual variation as well as diagnosis into account in the delivery of health care. Because genetic makeup is a major component of individual variation, the work of the Human Genetics Department is a central pillar for achieving our vision of modern medicine, and the scientists in the Department are key contributors to making this happen. Major disease areas of interest to Genentech include a range of chronic inflammatory and neuro-degenerative conditions, as well as diverse cancers, and a number of ophthalmic and metabolic diseases. Though the principal focus of this position will be in Neuroscience, we expect the research findings to have broad relevance across all disease areas. Genentech provides an exceptional research environment composed of internationally recognized scientific leaders, as well as state of the art core facilities with cutting edge technologies and computational resources to support your research activities. We provide a highly collaborative community, and as such, you will interact closely with clinical development teams and other scientists in the areas of biomarkers, bioinformatics, and research discovery departments including Immunology, Neuroscience, Infectious Diseases, Cancer Immunotherapy, and Molecular Oncology. Qualified candidates will typically have the following attributes: • PhD training with a strong focus on human genetics, Computational Biology or a related field; • Substantial (typically at least 3-5y) experience in academia or industry (as a postdoc or equivalent role) engaged in computational biology research or a related field • A thorough understanding of biostatistics & statistical genetic methods • Extremely strong computational skills, with demonstrable competence in the management and analysis of large scale data, proficiency in high-level programming languages and statistical computing • An excellent record of scientific publications in top tier journals • Strong communication and interpersonal skills with the ability to present and explain findings to a diverse audience • Motivation and ability to succeed in a fast-paced, highly collaborative environment • A keen interest in applying computation to solve biological problems and achieve translational goals • A scientific background in neuroscience would be a plus, but is not essential • Experience in the application of AI/ML methods would be a major plus Who We Are A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. Genentech has multiple therapies on the market for cancer & other serious illnesses. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page

We are looking for a part-time Bioinformatics Research Assistant to join our team. You will have the opportunity to work on a diverse set of initiatives led by the AllStripes research team, and will also contribute to cross-functional projects with our product, abstraction, and operations teams. You should love solving problems, working collaboratively, and working in research. What you’ll do... • Work with the research, product, and abstraction teams to develop and implement study protocols, track research study progress, assist with data quality control processes, and maintain our library of clinical data elements and surveys • Assist the research team with a variety of projects, including collaborative research programs, insights for the patient community, and new features on our two sided life sciences data platform • Support the development of relationships with key stakeholders in the rare disease space • Program all unstructured data studies and recommend improvements to increase efficiency and quality • Program all surveys and recommend improvements Who you are • A student enrolled in a graduate program in a biomedical science or clinical field (biomedical PhD or MS, MD, DO, genetic counseling, nurse practitioner or doctorate of nursing, PA, PharmD). • Past research experience (basic or clinical research) • Working knowledge of computer programming languages (R and/or SQL highly preferred) • Experience working collaboratively with others on long-term projects • Endlessly resourceful and self-motivated; you’re not afraid to dive into a complex problem • While hours will be flexible week to week, on average, be able to dedicate 10–20 hours per week to AllStripes (remotely). Most work can be completed on your own time. Contract will extend through June 2023, with the possibility of renewal. About the Hiring Manager: Caitlin Nichols - Research Director

SENIOR BIOINFORMATICS SCIENTIST BAY AREA OR REMOTE... $140,000-$155,000 THE COMPANY This global biotech leader is searching for a Sr Bioinformatics Scientist to join their team. The team focuses on single-cell NGS technology where they develop and manufacture healthcare products. Role & Responsibilities: Develop machine learning and statistics software to process data Develop and optimise signal processing algorithms Collab with scientists, engineers, bioinformaticians, and data scientists to identify analysis opportunities Skills: PhD in Computer Science, Computational Biology, or Bioinformatics Python Industry experience designing machine learning algorithms/pipelines from scratch Cloud experience Past signal processing is highly desirable Benefits: $140,000-$155,000 Bonus Equity Remote potential Please apply and send your CV

Career Category Clinical Job Description HOW MIGHT YOU DEFY IMAGINATION... You’ve earned your degree. How will you use that achievement to reach your goals? Do more with the knowledge you’ve worked hard to acquire and the passion you already have. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Become the professional you are meant to be in this meaningful role. Scientist - Proteomics, Bioinformatics, Computational Biology Live What you will do The Discovery Proteomics group at our South San Francisco campus is tasked with developing and implementing proteomic characterization technologies in support of Amgen’s early discovery pipeline Let’s do this. Let’s change the world. In this vital role you will you will conduct statistical analysis, data ingestion, and computational pipeline development for internal and external mass spectrometry-based and other type of proteomics data to support biomarker discovery, target validation, experimental design, and mechanism‐of‐action studies. You will work closely with other lab-based scientists in the Discovery Proteomics group, genomics, and software engineers in the Research Informatics team to support multi-omics data integration. Demonstrated expertise in modern data analysis and statistical Specific responsibilities include but are not limited to: • Enable Amgen’s preclinical pipeline through delivery of innovative technologies and technical expertise • Implementation of data analysis, management, and visualization • strategies for the complex proteomics and posttranslational data generated by mass spectrometry and other technologies. • Develop and establish computational solutions for differential protein expression analysis, protein turnover rate estimation, and protein-protein interaction identification. • Work across genomic and proteomic platforms, and potentially other ‘omic’ platforms, for data integration and mining, applying available external resources where appropriate. Win What we expect of you We are all different, yet we all use our unique contributions to serve patients. The highly motivated computational biologist/bioinformatics professional we seek is a scientist with expertise in mass spectrometry-based proteomics with these qualifications. Basic Qualifications: Doctorate degree Computational Biology, Bioinformatics, Statistics, Proteomics, Biology OR Master’s degree and 4 years of scientific experience OR Bachelor’s degree and 6 years of relevant experience Preferred Qualifications: Expertise in large-scale quantitative proteomics and other omics data analysis. • Laboratory experience in proteomic workflows, sample preparation or related techniques. • Proficiency in Python/R/SQL/Java and familiarity with analytic techniques/packages necessary for statistical analysis, data processing, data visualization, and machining learning. • Good practice in coding project management and reproducible data analysis. • Solid understanding in the Unix/Linux and cloud computing (AWS) environment. • Experiences in analyzing large scale protein interactions, protein turnover, and/or posttranslational modification studies. • Knowledge of proteomics data processing pipeline such as Proteome Discoverer, Spectronaunt, Skyline, MaxQuant, DIANN, MSstats, or OpenMS. • Strong background in biology or chemistry, especially as it pertains to human disease in the fields of Immunology, Oncology, Inflammation, and Cardiometabolic Disease. • Basic understanding in genomics and transcriptomics technologies and data properties. Thrive Some of the vast rewards of working here As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being. • Full support and career-development resources to expand your skills, enhance your expertise, and improve your potential along your career journey • A diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act • Generous Total Rewards Plan—comprising health, finance and wealth, work/life balance, and career benefits—with compensation and benefits rated above 4 stars (out of 5) on Glassdoor Apply now for a career that defies imagination Objects in your future are closer than they appear. Join us. careers.amgen.com Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen requires all staff in the United States and Puerto Rico to be vaccinated from COVID 19 as a condition of employment. In accordance with applicable law, Amgen will provide reasonable accommodations to staff members who qualify on the basis of a medical reason or a sincerely held religious belief, practice, or observance. Such accommodation may not pose an undue hardship to Amgen, its operations, or its staff. Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance

Mammoth BioSciences OPPORTUNITY Mammoth is seeking a Scientist I with protein modeling and bioinformatic/data science experience to contribute to protein engineering efforts in its growing Discovery team. The Discovery team is responsible for developing novel CRISPR-associated (Cas) nucleases for genome editing applications. The successful candidate will be responsible for generating molecular... protein-nucleic acid models and using bioinformatics and machine learning approaches to contribute to protein engineering efforts. The candidate will also be responsible for building analysis and visualization tools for large screening datasets. This is an excellent development opportunity for researchers who want to learn new skills and start their career working on cutting-edge CRISPR technologies. KEY RESPONSIBILITIES • Generate protein-nucleic acid structural models and use machine learning approaches to inform enzyme engineering efforts • Deploy data analysis and visualization tools for protein engineering campaigns • Design tools to support HTP molecular biology efforts for protein engineering campaigns • Analyze NGS datasets to interpret engineering outcomes and inform next steps • Provide regular updates at internal meetings • Other duties as assigned REQUIRED QUALIFICATIONS • Bachelor's degree in a relevant scientific discipline +5 years industry experience, M.S. +3 years, or PhD • Expertise using protein modeling and structural analysis software applications (Rosetta, RoseTTAFold, AlphaFold, etc.) • Python programming skills and experience using common bioinformatics software (BioPython, BLAST, MMSeqs, HMMer) PREFERRED QUALIFICATIONS • Expertise in analyzing large datasets and applying machine learning approaches for to protein design and engineering • Hands-on experience in the following areas: molecular biology (PCR, DNA/RNA purification and quantitation); biochemical and cell-based assays; CRISPR gene editing in mammalian cells BENEFITS • Company-paid health/vision/dental benefits • Unlimited vacation and generous sick time • Company-sponsored meals and snacks • Wellness, caregiver and ergonomics benefits • 401(k) with company matching COMPANY Mammoth Biosciences is harnessing the diversity of life to power the next generation of CRISPR products. Through the discovery and engineering of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. Mammoth aims to develop permanent genetic cures through best-in-class in vivo and ex vivo therapies and to democratize disease detection with on-demand diagnostics. Mammoth can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Based in the San Francisco Bay Area, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Redmile Group, Foresite Capital, Senator Investment Group, Sixth Street, Decheng, Mayfield, NFX, and 8VC, along with leading individual investors including Brook Byers, Tim Cook, and Jeff Huber. TEAM Our small-size proteins, such as Cas14 and CasPhi, are poised to transform disease treatment enabling novel editing approaches and delivery options that are difficult to achieve or not even possible with previously described CRISPR-Cas systems. Our teams are responsible for discovering and engineering novel CRISPR systems, establishing CRISPR-based diagnostics, and translating our unique CRISPR technology into therapeutic treatments with the ultimate goal of cures for indications with high medical need. It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law. This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation. Mammoth Biosciences requires that all employees be vaccinated against Covid-19 as a condition of at-will employment, with exceptions for medical or religious reasons in compliance with local, state, and federal law. PI

BIOINFORMATICS ENGINEER BAY AREA OR REMOTE... $95,000-$105,000 THE COMPANY This global biotech leader is searching for a Bioinformatics Engineer to join its team. This will be an entry-level role working closely with their computational team. They work on the development of kits, reagents, and instruments to develop tools to accelerate discovery efforts. Role & Responsibilities: • Building cloud infrastructure for bioinformatics scientists • Build internal web apps for scientists • Work closely with R&D, sales, and technical support teams Skills: • Bachelors or Masters with 1-2 years industry experience or PhD with no industry experience in Computer Science, Bioinformatics, or other quantitative related fields • Python or Java • Cloud experience with a preference for AWS • Docker or CI/CD experience • Web app development experience Benefits: $95,000-$105,000 Bonus Remote potential Please apply and send your CV

Invitae is a biotechnology company focused on providing tools and services for clinical research applications of genomics. Our mission is to unlock the power of precision medicine in improving patient care by providing a technology platform to advance genomics and facilitate collaborative research. Invitae is seeking Bioinformaticians to join our team. This role will be centered around... developing tools and pipelines that facilitate smooth business operations around multiple projects. The Bioinformatics Scientist will help develop systems for the efficient management of clinical and non-clinical data and be an interface to internal and external stakeholders. You will be responsible for scaling our pipelines as we work toward our goal of providing low-cost genetic answers to billions of people. The Bioinformatics Scientist must be skilled in programming and be able to solve common and complex bioinformatics problems. The ideal candidate should be able to perceive a problem clearly and dissect it into components which can be resolved programmatically. This role will be centered around creating tools, algorithms, and pipelines to complement new assay/product development. Having a fundamental grasp of genomics will be key to succeeding in this role. The candidate should be independent, well organized and collaborative with clear communication skills. In addition, the ability to frequently switch between tasks will be helpful. The Bioinformatics Scientist will report to the Head of Bioinformatics. Responsibilities: • Build scripts, tools, and algorithms to advance assay/new product development • Build Bioinformatic workflows/pipelines using Nextflow in a system agnostic manner • Participate in support activities when needed for operational excellence • Develop standard methodologies for analysis of NGS data including optimization of parameters, and consensus approaches across various tools • Work closely with the other staff to identify gaps in variant detection and annotation algorithms in current pipeline • Review, understand, and stay in compliance with Invitae HIPAA Security policies and procedures Qualifications: • MS/PhD in Bioinformatics or Computational Biology • 3+ years experience Proficient in R/Python, • nix, and SQL for data analysis • Working knowledge of standard bioinformatic tools used in NGS pipelines • Proficiency in Genomics and Molecular Biology • Solid understanding of Illumina sequencing technologies and metrics • Formal software development experience Bonus points for any experience with: • Formal statistics background • Understanding of Cloud Computing • Shared High-Performance Computing (HPC) environments e.g. S/UGE, LSF • Distributed Workflow managers, e.g. nextflow, luigi, COSMOS • Using and designing RESTful and RPC-style interfaces • Docker or other containerization/virtualization • CI/CD We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance

Responsibilities • Apply bioinformatics and structural biology tools to the design and optimization of RNA-programmable genetic medicines • Utilize public resources (data sets and tools) for target identification, structure prediction, and single-cell characterization... • Collaborate closely with other computational and bench scientists on the experimental design and analysis of results in a tightly integrated design/build/screen/analyze optimization cycle • Develop and apply workflows for analysis of multi-omic, sequence, and cell biology data from public sources and in-house experiments • Demonstrate validity of new methods through prototypes and benchmarking using appropriate controls • Apply biological understanding to selection of approaches and tools, and to computational analysis of candidates and targets • Communicate findings clearly to a broad audience with a range of technical, analytical, and biological expertise and present results on a regular basis at Research group meetings • Influence cross-functional teams to design studies that answer the most impactful questions facing a project • Provide and receive feedback that supports the growth and development of team members Qualifications • PhD in bioinformatics, computational biology, genetics, or related discipline with 5+ years of academic or industry experience, or MS with 7+ years of academic or industry experience • Strong scientific background including an understanding of molecular biology, genomics, and proteomics • Significant previous experience in bioinformatics and genome analysis tools/processes (e.g. working with NGS data, bioinformatics pipeline construction, interfacing with large-scale public datasets, etc) • Proficiency with methodologies in computational and structural biology, such as multi-sequence alignment and protein structure visualization (e.g. PyMOL) • Fluency in Python, R, and git • Familiarity with cloud-based services such as AWS and Google Cloud

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we... perform. In return, we’ll help you build a career that you can feel passionate about. Job Summary The individual in this position will be member of the senior scientific leadership staff of the group. The position requires outstanding competencies of bioinformatics within and outside the field of application. The individual has demonstrated deep understanding of scientific and technical principles, theories, concepts and techniques. Conceptualizes and develops new methods and procedures with help of scientific literature. Demonstrates strategic influence to expedite defined scientific area. Defines own scientific objectives aligned to project goals and suggests new ideas or initiatives. Essential Duties and Responsibilities • Develop, perform and troubleshoot bioinformatics data processing and analysis across phage antibody discovery campaigns using NGS and Sanger sequencing, • Design and QC phage antibody libraries for primary lead discovery, and optimization of existing leads. Interact with research clients regularly to explain hypothesis and analyses • As a member of the site leadership team contribute to all research plans. • Will manage a small team. • Function as the primary contact for the planning related to bioinformatics analysis and method development. • Recognizes and provides, using clear scientific rationale, solutions to a variety of technical problems of increasing scope and complexity within projects and client facing. • Prepare and present out of scope data analysis reports and communicate insights internally and externally. • Perform oversight of bioinformatics scientists and mentor junior staff in areas such as experimental design, workflows and processing procedures. • Perform troubleshooting on data processing and analysis tasks within and outside standard project scopes. • Continuously review scientific literature in the field and outside to scout new technologies and scientific advances. Conceptualize, design and implement with help of junior staff. • Attend and present at international scientific meetings. • Perform all other related duties as assigned Job Qualifications Qualifications •Education: Master’s degree (MS/M) in relevant field with adequate experience. PhD degree in bioinformatics or a scientific related discipline is preferred. •Experience: Minimum of 8 years of related experience in contract research, academic or pharmaceutical industry. Minimum of 6 years of field related bioinformatics experience. Vaccine Mandate Charles River is a U.S. Federal Contractor. As a result, we must follow the Presidential Executive Order to mandate vaccinations, and ensure our employees are fully vaccinated against COVID-19. Our main priority is the wellbeing, health, and safety of our people. We require proof of vaccination from all employees. Anyone with requests for disability-related and/or religious exemptions should contact Talent Acquisition (crrecruitment_US@crl.com) so that information can be provided about the accommodation process at Charles River. About Discovery Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market. About Charles River Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market. With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 86% of the drugs approved by the FDA in 2021. Equal Employment Opportunity Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status. If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications. For more information, please visit www.criver.com

Surrozen is a biotechnology company focused on discovering and developing novel regenerative medicines with a focus on unlocking the powerful self-renewal properties of the body through specific control of the Wnt signaling pathway. Our vision is to engage the body’s own biological tissue repair mechanisms with our targeted regenerative antibodies, overcoming research and development hurdles... that have been previously intractable, and have held back drug development efforts in the promising area of Wnt biology. Bioinformatics Research Associate Surrozen is recruiting a Research Associate to be involved in the design and analysis of experiments that apply high-throughput technologies such as single-cell and single-nuclear RNA-sequencing and spatially resolved transcriptomics to mechanism of action and biomarker discovery efforts. In this role you will also explore innovative approaches to combining data from multiple experimental modalities to inform discovery efforts and therapeutic development. This is an exciting opportunity to work with state-of-the-art techniques and analytical approaches on intriguing and challenging biological questions. The preferred candidate will bring enthusiasm, intellectual curiosity, critical thinking, scientific integrity, and a desire to understand biological principles of developing regenerative medicine therapeutics. Responsibilities • Analyze complex in-house scRNA-seq data with multiple experimental conditions in a range of tissues to contribute to mechanism of action and biomarker studies • Interrogate in-house and public bioinformatics data such as functional genomics (e.g., RNA-seq, scRNA-seq, spatially resolved transcriptomics, ATAC-seq, Chip-seq) and imaging data • Conduct rigorous, thorough analyses following best practices and using state-of-the-art approaches • Compose detailed analytical reports, concise and clear key summaries, and quality visualizations • Collaborate with scientists who work at the bench and interact closely with others doing bioinformatics analyses • Bachelor’s or Master’s in Bioinformatics, Biostatistics, Genomics, Computational Biology, or other relevant quantitative field required • Strong background in biology • At least one year of relevant experience (including graduate school) in biomedical data analysis • Demonstrated success analyzing bioinformatics data, especially RNA-seq and/or scRNA-seq is required • Experience working independently on analysis problems and also working collaboratively with biologists to understand critical questions and context • Fluent in relevant languages for data analysis (R required, Python) • Experience with Bioconductor packages and workflows We are an Equal Opportunity Employer offering a competitive salary and benefits