Bioinformatics Jobs

Principal Investigator, Simon Knott, PhD is looking for a Postdoctoral Scientist to join the team! The Cedars-Sinai Center for Bioinformatics and Functional Genomics (CBFG) is an integrated, interdisciplinary research group with the common goal of developing end-to-end research workflows for genomic and high-throughput functional analysis of patient samples. The primary goals of the CBFG are to... establish a research nexus that integrates leading-edge developments in computational sciences, next-generation genomics and epigenomics, and to use functional biology to improve our understanding of disease etiology applied to personalized health. The Knott laboratory at Cedars-Sinai Medical Center is searching for a Postdoctoral Scientist with a strong background in tumor biology and the immune microenvironment to lead single cell-based omics studies of immunotherapy clinical trials being carried out at the medical center. The scientist will manage a team of laboratory technicians through the processing of clinical trial biopsies for profiling with single cell RNA and ATAC sequencing as well as other emerging technologies. Additionally, our laboratory analyzes the clinical samples with spatial profiling methods such as Co-Detection by Indexing, which allows us to directly study interactions between neighboring cells within the tumor that may govern the response to therapy. We are currently analyzing trials to study the effects of combination immunotherapies in patients with triple negative and estrogen receptor positive breast cancers. We are also beginning trials in patients with early as well as late stage Her2 positive disease. We expect all analyses of these cutting-edge clinical trials will result in high-profile publications in top-tier scientific journals. To learn more, please visit: Knott Research Lab | Cedars-Sinai. Are you ready to be a part of breakthrough research? Working independently but in close cooperation and in consultation with Dr. Knott and other Research Scientists, the Postdoc will perform routine and complex laboratory procedures throughout training period. May develop, adapt, and implement new research techniques and protocols, analyze and interpret data. #Jobs Primary Job Duties and Responsibilities: • May assist in preparation of grant proposals, but is not responsible for generating grant funds. • May participate in publications and presentations as author or co-author. • Designs and performs experiments. Will keep appropriate experimental records and documentation and analyze the results with the Principal Investigator. • Analyzes, interprets, summarizes and compiles data. • Operates and maintains equipment and instruments. Education: • Doctorate Degree in Cancer Biology, Immunology or a related field, required. Experience and Skillset: • Acquires thorough technical and theoretical knowledge of research project and objectives during one to five (1-5) year post-doctoral appointment. • Experience analyzing murine or human tumor microenvironments with single cell resolution methods. • Molecular biology skills are also required, as this scientist will be responsible for guiding laboratory technicians through specific analytical techniques mentioned. • Ability to interpret high-dimensional data and a willingness to work in a collaborative setting with clinicians, immunologists and computational scientists is essential. • Works independently on research projects designed by a mentor (typically the PI) within area of specialization. • Demonstrated aptitude to perform experimental protocols and procedures, including detailed data collection, and analysis, and operation and maintenance of specialized equipment. • Knowledge of safety standards and maintenance of specialized equipment. Working Title:Postdoctoral Scientist - Knott Lab - Bioinformatics & Functional Genomics Department:BMS - Bioinfo & Func Genomics Business Entity:Academic / Research Job Category:,Academic/Research,Academic/Research Job Specialty:Postdoctoral Position Type:Full-time Shift Length:8 hour shift Shift Type:Day

Job Summary The Bioinformatics Core at Purdue supports biological research efforts across the University through data analyses combining research in biology with information technology in order to collect, analyze and interpret data. In this role, you will use computational tools to gather and analyze data, compile vast amounts of information from activities such as gene expression profiling and... epigenomics, etc., especially in non-model organisms and consult with other scientists and researchers to analyze data sets, collaborate with other 'omics' centers. Additional duties will include: • Assist the Director in managing the core, develop new services, market current services, developing and conducting workshops and developing pipelines for data analysis • Perform analysis of sequencing data from various sequencing platforms using different software packages and in-house scripts • Analyzing large scale genomic and transcriptomic data, developing project specific workflows • Validating various software packages • Help the director to plan and implement analysis methods and manage the projects • Document the analysis process, workflows, interpret results, and help other staff to maintain these standards • Attend conferences, trainings, seminars, and professional group meetings Required: • Ph.D. degree in Bioinformatics, Computational Biology, Molecular Biology or related field • 3 years of experience working in a core facility or similar settings • An equivalent combination of education and experience may also be considered • Strong biological science background, preferably non-model organisms; experience in genomics, and experience in handling large data sets from various NGS platforms • Experience in handling large and complex data sets with particular emphasis on Next Generation Sequencing and associated bioinformatics analyses • Experience in the use and application of bioinformatics software and tools to address biological research needs • Experience in training and supervising graduate students and staff working in bioinformatics analyses • Experience in SNP identification and detection, CNV analysis, RNA-Seq, ChIP-Seq, Metagenomics/Metatranscriptomics analyses • Experience in using UNIX/LINUX OS and PERL/Python scripting • Experience in using 'R' • Knowledge of genomics concepts, including sequence assembly, gene prediction and annotation, alignment etc. • Must be able to communicate effectively with users of the Bioinformatics Core • Highly motivated and detail oriented • Strong visual, verbal, and written communication skills • Excellent time organizational skills Additional Information: • All new hires will be expected to follow Protect Purdue guidelines • To learn more about Purdue’s benefits summary • A background check will be required for employment. • FLSA: Exempt (Not Eligible for Overtime) • Retirement Eligibility: Defined Contribution Immediately • Purdue University is an EOE/AA employer. All individuals, including minorities, women, individuals with disabilities, and veterans are encouraged to apply

Bioinformatics Trainer / Analyst OverviewCompetitive salaries and full benefits including, medical, dental, and vision insurance, retirement program, vacation and sick leave, onsite cafe and much more!The Oklahoma Medical Research Foundation (OMRF) is an independent, not-for-profit, biomedical research institute adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC... located in Oklahoma City. OMRF investigators have internationally recognized expertise in Autoimmunity, Immunology, Genetics, Aging, Cardiovascular Disease, and Cancer. Investigators at OMRF enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs. Additional information about OMRF can be found at the Oklahoma Medical Research Foundation web site: www.omrf.org.OMRF’s excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic. ResponsibilitiesThe Center for Biomedical Data Science is seeking a bioinformatician/data analyst to support biomedical research projects and training across the institute. The hire will implement and optimize pipelines for genomic data analysis and facilitate training of individuals in the use of a variety of software, including R and Python packages, for the analysis of datasets from a variety of genomic methods, including RNAseq, ChIPseq, and scRNA-seq. The hire will also work with senior scientists and staff to organize and implement access to training materials and software. QualificationsBachelor’s degree in Bioinformatics, Mathematics, Statistics, Biostatistics, Computer Science, MIS, or a relevant field and 3 years relevant experience/training in a biomedical research setting or combination of experience/education.Candidates must have prior hands-on experience in genomic data analysis using R and/or Python packages. Preference will be given to candidates who have demonstrated strong skills in project management, contribution to multiple projects, customer service, verbal and written communication, time management, organization, and experience with education/training.To apply, visit https://careers-omrf.icims.com/jobs/1474/bioinformatics-analyst/job?in_iframe=1OMRF’s excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic.jeid-c1ec480f5f06de488bb8e9b64865e241

Bioinformatics Analyst - Genomics (Open to remote) This established company is offering you the unique opportunity to hone your Bioinformatics skills in a high-support environment. Your Bioinformatics data analysis experience in combination with your go-getter attitude and quick-learning spirit will help you shine in this role. Join a close-knit team and make a name for yourself at an industry... leading company - apply below. What you'll do: Working knowledge of Python, Perl, and R is ideal not required. Knowledge in basic biological processes and genomics. Familiarity with genomics databases such as gnomAD, dbSNP, ClinGen and ClinVar. Work with NGS data sets. Working knowledge of laboratory protocols relevant to sequence analysis. Excellent verbal and written communication skills. Ability to multi-task and work in a fast-paced environment. Who you are: Education and Experience Requirements M.S. in statistics, bioinformatics, genomics or computational biology or equivalent experience Experience in biotech preferred Why work here: Supportive leadership: you'll be directly reporting to a competent, devoted and kind manager with a reputation for building successful leaders Impact: Have a positive influence both as part of a lean team where your voice can be heard, as well as on the company as a whole Job Type: Full-time Pay: $90,000.00 - $135,000.00 per year Benefits: Dental insurance Health insurance Vision insurance Schedule: 8 hour shift Monday to Friday Ability to commute/relocate: San Diego, CA 92121: Reliably commute or planning to relocate before starting work (Required) Experience: Bioinformatics : 1 year (Required) NGS: 1 year (Preferred) Work Location: One location

Description Purpose... The scientist works independently using a robust math toolbox to discover solutions for a diverse portfolio of interesting and challenging problems. The scientist develops, implements, and monitors advanced analytic, medical informatics, and predictive modeling tools for health care programs at the UPMC. The scientist normally works Monday through Friday day-light business hours or as needed. Responsibilities: • Maintain SOP documentation related to bioinformatics processes such as NGS data analysis pipelines. • Development and maintenance of robust systems for managing and reporting NGS results. • Development and maintenance of Next-Generation Sequencing (NGS) data analysis pipelines. • Assist with technical interpretation of NGS results in areas such as variant calling, copy number variation, or fusion detection. • Assist in the establishment of cutoffs and guidelines for interpretation of NGS results using statistical analysis. • Work with other lab members to publish new methods and results in scientific journals and conferences. Qualifications • Ph.D. degree in Bioinformatics, Computer Sciences or Biology with with 1 years experience in a computational role OR M.S. degree M.S. degree with 2 or more years experience in a scientific role • Requirements: Linux/Unix.Python.Next-Generation Sequencing data analysis experience. • Strong analytical skills. • Experience with Django, SQL, R, HTML/CSS, Javascript preferred. • Familiarity with commonly used databases and bioinformatics tools (e.g. samtools, bedtools, IGV, ANNOVAR, GATK) and file formats (e.g. BED, VCF, FASTQ, BAM) preferred. • Excellent written and oral communication skills. • Person must demonstrate a high degree of professionalism, enthusiasm and initiative on a daily basis. • Ability to work in a fast-paced environment a must. • Attention to detail is critical to the success of this position Licensure, Certifications, and Clearances: • Act 34 • UPMC is an Equal Opportunity Employer/Disability/Veteran

Payroll Title: BIOINFORMATICS PROGR 2 Department: PSYCHIATRY Salary Range... Commensurate with Experience Worksite: Campus Appointment Type: Career Appointment Percent: 100% Union: Uncovered Total Openings: 3 Work Schedule: Days, 8 hrs/day, Monday-Friday As a federally-funded institution, UC San Diego Health maintains a marijuana and drug free campus. New employees are subject to drug screening. #114801 Bioinformatics Programmer Extended Review Date: Mon 6/27/2022 Apply Now For the safety and well-being of the entire university community, the University of California requires, with few exceptions, that all students, faculty and staff be vaccinated against the COVID-19 virus and influenza before they will be allowed on campus or in a facility or office. For more information visit: Flu Vaccine Mandate / COVID Vaccine Policy This position will remain open until a successful candidate has been identified. UCSD Layoff from Career Appointment: Apply by 03/02/2022 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor. Special Selection Applicants: Apply by 03/11/2022. Eligible Special Selection clients should contact their Disability Counselor for assistance. This position will be hired at the Bioinformatics Programmer 2 or Bioinformatics Programmer 3 level depending on the experience of the selected candidate. DESCRIPTION UCSD Department of Psychiatry is one of the most innovative and productive academic departments in the country, offering challenging career opportunities in the diverse areas of advanced educational programs, cutting-edge research, and state-of-the-art clinical services. The department is committed to offering a dynamic learning environment and growing opportunities to its talented and dedicated employees. Under general supervision, the incumbent will work as a Bioinformatics Programmer researching the development of a comprehensive understanding of the gene regulatory network and how aberrant gene regulatory circuits contribute to human disease within the Department of Psychiatry. Utilizing single cell transcriptomics and single cell epigenetics to understand dysregulated gene regulatory circuitry in Alzheimer’s disease and substance use disorder. Responsibilities include analyzes and interprets experimental results using bioinformatic methods in a self-directed manner. Produces quality/quantity reproducible scientific data and analyses, generating figures for publication and writing manuscript. The incumbent also will make contributions to scientific literature, conferences or otherwise plays a key role in the advancement of the research project(s) and/or Institute goals. MINIMUM QUALIFICATIONS • Six (6) years of related experience, education/training, OR a Bachelor’s degree in biological science, computational/programming, or related area plus two (2) years of related experience/training. • Working knowledge of bioinformatics methods and data structures. • Working knowledge of modern biology and applicable field of research. Knowledge as it relates to DNA sequences, sequencing technologies and genomics. • Ability to communicate technical information in a clear and concise manner. Cooperative and service-oriented attitude; must be able to work under pressure and maintain a professional demeanor. • Working knowledge of applications programming and web development. • Working knowledge of databases. • Working knowledge of application and data security concepts. • Possesses highly specific or sophisticated skills and exhibits expert knowledge essential to the work of the laboratory, project or department. • Ability to effectively supervise scientific, research and/or technical staff. • Demonstrated contribution to a project(s) and/or paper(s). • Proven ability to conduct investigations in relevant scientific areas, formulate experimental hypotheses, and analyze and interpret scientific data. • Strong interpersonal skills; ability to effectively interact with all levels of staff and external contacts; ability to work as an effective team member. • Demonstrated experience with data analysis and interpretation of single cell functional genomic datasets. • Knowledge of and experience in working with junior and senior bioinformatics programmers, and in utilizing software to conduct data analysis and interpretation of single cell functional genomic datasets. SPECIAL CONDITIONS • Employment is subject to a criminal background check. • Must be able to work overtime or in the evenings. Apply Now Job offer is contingent on successful engagement in the UC COVID-19 Vaccination program (fully vaccinated with documented proof or approved exception/deferral). If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable. UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team! Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached. To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community. UC San Diego Health is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age, protected veteran status, gender identity or sexual orientation. For the complete University of California nondiscrimination and affirmative action policy see: http://www-hr.ucsd.edu/saa/nondiscr.html UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information

The Department of Laboratory Medicine and Pathology (LMP) at the University of Minnesota Medical School is seeking to hire an academic track or tenure track faculty member interested in the interface of bioinformatics, machine learning, and the medical sciences. As the acquisition of biomedical data has become increasingly scalable, the challenge is shifting from obtaining data to identifying... relevant data and analyzing and interpreting it relative to the existing knowledge of research. Often data is collected across multiple modalities including various imaging and ‘omics platforms, each with its own associated databases. In addition, digital pathology and spatial ‘omics platforms are extending the computational needs beyond the realm of traditional ‘omics analysis into complex image analysis. Our goal is to develop tools that leverage the multilayered nature of the data to establish relationships between modalities and direct experiments using advanced computational methodologies. The candidate will work closely with the Advanced Research and Diagnostics Laboratory (ARDL) within LMP, which is the central laboratory and biorepository for over 60 NIH funded multi-center observational studies and clinical trials and both generates and has access to large scale ‘omics data on several thousand samples. The applicant will also work closely with the Divisions of Computational Pathology and Anatomic Pathology to advance digital pathology applications within LMP.Candidates must hold a PhD in Biophysics/Physics, Applied Mathematics, Computer Science, Statistics, Quantitative/Computational Biology or a related field. Strong background in statistics, experience implementing machine-learning algorithms, building analysis pipelines for ‘omics data and demonstrated ability to extract datasets from publicly available sources. Academic rank and appointment type will be commensurate with years of experience and accomplishments. Candidates are expected to demonstrate a strong record of research productivity. Successful candidates must have the ability to: Obtain external funding to support innovative research. Represent the Department and the University at professional meetings in local communities, nationally and across the world. Assist in the recruitment of the best and brightest doctoral students, postdoctoral fellows and molecular pathology fellows and mentor them throughout their years of study. Obtain external funding for their support while working on research projects under the faculty member’s supervision. Publish seminal research findings in refereed, high impact journals, book chapters and books. Collaborate with other faculty to obtain research funding for trans-disciplinary research. The Department of Lab Medicine and Pathology recognizes and values the importance of diversity and inclusion in supporting the academic mission. Applications from individuals with a diversity of backgrounds and experiences, including those from underrepresented groups, are highly encouraged.The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu.To apply for this position go to https://www.umn.edu/ohr/employment/index.html and go to search postings and enter the requisition 351447. Please upload a cover letter, CV, a brief statement of research interests, and the names and contact information for at least three references. The University of Minnesota is an equal opportunity educator and employer

The Bioinformatics group at Codiak is looking for a talented and motivated candidate to deliver on our mission of advancing bioinformatics tools and genomics technologies to maximize the impact of the exosome therapeutic pipelines. The ideal candidate should have solid training in bioinformatics or related disciplines. The candidate is expected to develop and implement state-of-the-art... bioinformatics solutions and maintain internal bioinformatics pipelines, to provide bioinformatics supports to clinical and R&D by analyzing and interpreting high-throughput genomics and proteomics data, and to collaborate with bench scientists to develop exosome biology insights and ideas. The candidate will work in an exciting and interdisciplinary environment, teaming with several other internal groups in different stages of the discovery, preclinical pipelines, and ongoing clinical trials. The candidate should have strong domain knowledge in genetics and genomics, excellent programming skills, and deep experience with next-generation sequencing (NGS) and data analysis. Key Responsibilities • Design and implement analytical pipelines for analyzing and processing next-generation sequencing and biomarker data from clinical studies.; • Apply and improve existing bioinformatics pipelines and computational infrastructure to optimize analytical capabilities and robustness; • Integrate internal and public ’omics databases, data sets, and pathways to support target identification, target validation, and clinical biomarker discovery; • Maintain and optimize existing genomics data visualization framework; • Proactively engage with research, preclinical, and clinical teams in a matrix environment; • Present complex results, both verbally and in writing, to management, bioinformatics, and non-bioinformatics audiences. Requirements • PhD in bioinformatics, computational biology, statistics, computer science, or related discipline, or MS degree with 3+ years of experience; • Experience with analysis of NGS data from DNA, RNA, single-cell RNA sequencing studies; • Proficiency in using bioinformatics databases (TCGA, cBioPortal, RefSeq, dbSNP, ClinVar, etc); • Proficiency with programming languages (Python, Perl, R/Rshiny, C/C++, Java, etc) in Linux/Unix environment; • Experience with high performance cloud computing (AWS, GCP, Azure, etc); • Experience with Version Control software; • Experience with deployment containers (Docker, Singularity, Kubernetes, etc.); • Experience with data visualization tools and packages preferred; • Experience with machine learning techniques is a plus. • Ability to present and communicate technical data to broad audiences; • Excellent interpersonal and team skills; • Demonstrated ability to collaborate with cross-functional project teams; • Excellent oral and written communication skills in English. https://www.codiakbio.com/ Codiak BioSciences is an Equal Opportunity Employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status

Job Description Our IT team operates as a business partner proposing ideas and innovative solutions that enable new organizational capabilities. We collaborate internationally to deliver the services and solutions that help everyone to be more productive and enable innovation. Our Engineering team builds core components used by our Company's Research Labs’ data analytics, visualization, and management workflows. The analysis tools and pipelines built for data processing by our team in partnership with our scientists aim to accelerate research and the discovery of new therapies for our patients. We collect, annotate, analyze petabytes of scientific data (multi-omics, chemistry, imaging, safety) used in biomarker research, drug safety/efficacy, drug target discovery, and compendium diagnostic development. We help our scientists to process, analyze scientific data at scale by developing highly parallelized analytical workflows ran on HPC infrastructure (on-prem & cloud); to manage... explore and visualize various scientific data modalities by developing bespoke data models, bioinformatics ETL processes, data retrieval and visualization services using distributed micro-service architecture, FAIR data principles, SPA type dashboards, industry specific regulatory compliant data integrity, auditing, and security access controls. We are a creative and disciplined software engineering team, using agile practices and established technology stacks to design and develop large-scale data analytics, visualization, and management software solutions for local and on-cloud hosted HPC datacenters, as well as to integrate 3rd party analytical platforms with internal data workflows to address pressing engineering and data science challenges of life-science. We are looking for a bioinformatics engineer or a bioinformatics scientist with strong engineering acumen and interest, to join our team of software engineers, with an interest in developing novel computational approaches and analytical/storage solutions (automation/analysis pipelines, technical/scientific databases, and data models) as required by therapeutic research priorities; bioinformatics engineers, who can break down and solve complex problems, with a strong motivation and a pragmatic mindset to get things done, who are equally comfortable in troubleshooting software modules of molecular data analysis/visualization tools and workflows or in driving the design and implementation of statistical data analysis and ETL processing, data curation pipelines for large molecular datasets (such as raw microarray data, genomic sequence data, multi-omics data). Our engineers and scientists own their products end to end and influence the way how our products and pipelines are deployed to facilitate many aspects of drug discovery impacting hundreds of thousands of patients around the world. We are hoping that you are passionate about collaborating across the interface between hard-core software engineering, the development of bioinformatics applications for scientific and technical use, the development of scientific data curation and ETL processing pipelines on one hand and the research and discovery data analysis performed by molecular biologists, biostatisticians, biochemists, experimental biologists, clinical geneticists, and microbiologists on the other hand. Primary Responsibilities: • Drive product discovery and requirements clarification for ambiguous and undefined problems framed with uncertainty. Ability to creatively handle complex dependencies and ambiguous requirements, competing business priorities, while producing fit-for-purpose, optimal solutions. • Help design and implement engineering solutions and novel bioinformatics techniques and pipelines that facilitate research processes and scientific discovery in multiple areas of drug discovery, with a particular focus on tools and applications that help interpret, correlate, and extract biological meaning from data • Help manage technical and business dependencies and bottlenecks, balance technical constraints with business requirements, and deliver maximum business impact with solid customer experience • Be an effective collaborator in a cross-functional teams, i.e., work closely with scientists, peers and technical leads, business leaders and executives in different geographical locations to define and deliver complex engineering features. • Strong collaboration, organization skills are required, and the ability to effectively communicate with technical and non-technical audiences. Education Minimum Requirements: • Bachelor of Science (or Masters) in Computer Science and B.S. (or M.S.) in BioInformatics; or an equivalent cross-disciplinary qualification Required Experience and Skills: • Solid experience (3+ years) • of processing genomics datasets • of combined R, Python, R/Shiny development experience, with focus • on developing genomics data processing/analysis/quality control workflows • with storage of data built using AWS services, • with data published for consumption using R/Shiny and REST APIs • Proven ability (2+ years hands-on experience) • of development and running of data processing pipelines and scripted workflows • to work intuitively with modern data science visualization libraries (ggplot2, seaborne, plotly) • to summarize and render broad/deep biological data for human consumption • to work with core molecular biology technologies (i.e., differential expression, single cell genomics, functional genomics, sorted/bulk RNA-Seq) • to work with file formats (create, consume, convert, ingest them) used for molecular biology data (such as AnnData, HDF5, RDS) • to design, query relational data stores (SQL) • Hands-on experience with • with cloud services (AWS S3, EFS, EC2, Batch, RDS) • with one or more version control tools (Git, Mercurial) • Strong collaborator, communicator, and experienced with making technical partnerships with research and business teams • Strong problem-solving skills Preferred Experience and Skills: • hands-on experience with HTML, CSS, and JavaScript • experience developing and deploying containerized applications (i.e., Docker, Singularity) Our Support Functions deliver services and make recommendations about ways to enhance our workplace and the culture of our organization. Our Support Functions include HR, Finance, Information Technology, Legal, Procurement, Administration, Facilities and Security. Who we are … We are known as Merck & Co., Inc., Rahway, New Jersey, USA in the United States and Canada and MSD everywhere else. For more than a century, we have been inventing for life, bringing forward medicines and vaccines for many of the world's most challenging diseases. Today, our company continues to be at the forefront of research to deliver innovative health solutions and advance the prevention and treatment of diseases that threaten people and animals around the world. What we look for … Imagine getting up in the morning for a job as important as helping to save and improve lives around the world. Here, you have that opportunity. You can put your empathy, creativity, digital mastery, or scientific genius to work in collaboration with a diverse group of colleagues who pursue and bring hope to countless people who are battling some of the most challenging diseases of our time. Our team is constantly evolving, so if you are among the intellectually curious, join us—and start making your impact today. NOTICE FOR INTERNAL APPLICANTS In accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions. If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package. To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor. Residents of Colorado Click here to request this role’s pay range. MRLITPM New hires in office-based roles in the US & Puerto Rico will be required, subject to applicable law, to demonstrate that they have been fully vaccinated for COVID-19 or qualify for a medical or religious exemption to this vaccination requirement that can be accommodated without an undue burden to the operation. However, subject to applicable law, employees working in roles that the Company determines require routine collaboration with external stakeholders, such as employees in health services, customer facing commercial, or research based roles, will be required to be fully vaccinated as a condition of employment. Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. For more information about personal rights under Equal Employment Opportunity, visit: EEOC Poster EEOC GINA Supplement​ OFCCP EEO Supplement Pay Transparency Nondiscrimination We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace. Residents of Colorado: Click here to request this role’s pay range. Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: Regular Relocation: Domestic/International VISA Sponsorship: Yes Travel Requirements: 10% Flexible Work Arrangements: Remote Work Shift: Valid Driving License: Hazardous Material(s): Number of Openings: 1 Requisition ID:R196507

Computational postdoctoral positions in bioinformatics and epigenomics (computational/experimental) are available at Dr.Yaping Liu’s lab in the Division of Human Genetics at Cincinnati Children’s Hospital Medical Center (CCHMC) and the Department of Pediatrics at the University of Cincinnati College of Medicine (https://www.cincinnatichildrens.org/research/divisions/h/genetics/labs/liu ). One of... the research directions in Dr. Liu’s group is to study single-cell multi-omics data to understand the gene regulatory mechanism behind non-coding genetic variants. We have already developed several single-molecule (e.g. NOMe-seq, Kelly & Liu et al. 2012 Genome Research) and single-cell multi-omic technologies (e.g. single-cell Methyl-HiC, Li & Liu et al. 2019 Nature Methods). We are continuing to develop several novel multi-omic technologies ourselves (e.g. https://doi.org/10.1101/2022.03.29.486102), which have been supported by multiple internal and long-term NIH grants now. The new postdoctoral position is going to work on our own single-molecule and single-cell multi-omic technologies, integrate multi-omic signals from the same single cell, and finally understand the regulatory roles of non-coding genetics variants in the heterogenous cellular system.What We’re Looking For:○ Highly motivated in scientific research○ Ph.D. (recent/expected) in computational biology, bioinformatics, genomics or quantitative research fields.○ Proficiency with at least one high-level scripting language (R or Python) and Linux operating system (Bash).○ Excellent quantitative background in statistics and machine learning, and/or computational genomics background. Familiarity with large-scale next-generation sequencing (NGS) data analysis (WGS, WGBS, RNA-seq, ATAC-seq and/or related) and/or single-cell multi-omics.○ At least one decent first or co-first author SCI paper published or accepted.○ Fluent in English (spoken and written)CCHMC is located at Cincinnati, Ohio state (OH). It is the 2nd best children’s hospitals in the 2018-22 U.S. News & World Report and 3rd highest recipient of grants from the National Institutes of Health (NIH) for pediatric research. It is also ranked as 3rd best Department of Pediatrics at a US medical school, in U.S. News & World Report survey of best graduate schools. There are plenty of excellent research core facility support in CCHMC (details in https://www.cincinnatichildrens.org/research/cores ). Cincinnati is the 28th largest metropolis area in US and largest one in Ohio. Many companies’ headquarter are in Cincinnati, such as P&G, Kroger. Cincinnati Children’s is proud to be an Equal Opportunity Employer that values and treasures Diversity, Equity, and Inclusion. We are committed to creating an environment of dignity and respect for all our employees, patients, and families (EEO/AA). The anticipated start date is ASAP. Generous stipends will be paid according to NIH postdoctoral stipend levels with additional CCHMC benefit (e.g. healthy insurance, retirement plan and generous relocation package will be provided, details in https://www.cincinnatichildrens.org/education/research/postdoctoral ). If you are interested in applying Ph.D. position in Liu lab. Please also feel free to contact Dr. Liu and apply it this fall through BMI or MDB graduate program in CCHMC. Potential candidates are encouraged to send your CV and names and contact information of 3 referees to: Yaping Liu, Division of Human Genetics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA. Email: Yaping.Liu AT cchmc.org