Bioinformatics Jobs

POSITION SUMMARY The Simons Foundation is seeking a Bioinformatics/Senior Bioinformatics Engineer (dependant upon experience) to develop and support whole exome and genome sequence data analysis pipelines in both research and operational modalities. This position will report to the Director of Data and Analytics in the informatics group and will work with other engineers and analysts in the... informatics group, as well as with clinical and basic research teams at the foundation. This position will be based in Simons Foundation’s offices in New York City.ESSENTIAL FUNCTIONS/RESPONSIBILITIES Design, develop and operate computational pipelines for next-generation sequencing data Work on both large-scale projects and small custom tasks that span a wide variety of analysis problems Develop new and/or improve upon existing algorithms for variant detection (SNPs and indels) and structural variant detection (CNVs, inversions and translocations) for clinical research purposes Develop and maintain a knowledge base of variants and annotations discovered in processing of samples MINIMUM QUALIFICATIONSEducation Master’s degree or higher in bioinformatics, computational sciences or related field. Required Attributes At least 3+ years’ work experience in research-and-development setting in bioinformatics Experience with next-generation sequencing data Experience in Linux/Unix cluster environment Advanced programming skills in Python Strong background in algorithm development, statistical methods, machine learning and distributed computing. Extensive knowledge of computational genomics and experience with high-throughput data analysis Outstanding personal initiative and the ability to work effectively as part of a team Excellent verbal and written communication skills Desirable Experience Familiarity with C++, Perl, Matlab and R is desirable. Familiarity with databases – relational and noSQL – cloud computing and web services is desirable. The Simons Foundation’s Diversity CommitmentMany of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds and experiences, and we are committed to cultivating an inclusive work environment.The Simons Foundation actively seeks a diverse applicant pool and encourages candidates of all backgrounds to apply.We provide equal opportunities to all employees and applicants for employment without regard to race, religion, color, age, sex, national origin, sexual orientation, gender identity, genetic disposition, neurodiversity, disability, veteran status, or any other protected category under federal, state and local law. PI183190300

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for... patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world- changing projects, you will do more and become more than you ever thought possible. The Sr. Bioinformatics Support Scientist position is responsible for all aspects of customer success. This role is a field-based service and support role tasked with assisting customers on ultilizting Illumina technology and software products, with a focus on Data Sciences and applications. The successful applicant will be part of an award-winning customer support team that leads the industry in customer satisfaction. The Sr. Bioinformatics Support Scientist partners with customers, front line field personnel, and internal resources to provide pre-sales support, technical training, troubleshooting, and complaint resolution with respect to Illumina data, instruments, and bioinformatic solutions as well as experimental and workflow design. This position serves as a scientific and technical expert consultant during pre- and post-sales activities, and an consultant to development. This position will collaborate with broader commercial and product teams to maximize customer satisfaction and to improve software product adoption. This role requires expert-level troubleshooting, communication, time management, situational awareness, poise under pressure, and collaboration. You will be expected to build and maintain strong relationships with internal and external stakeholders across the region including Sales, Service and Support teams, and customers as well as Marketing and Product teams. Responsibilities • Consult on complex pre-sales engagements in partnership with Illumina sales personnel, including evaluation support, discussions on bioinformatics and data analysis, and helping customers design analytic workflows. • Engage with customers in post-sales contexts to ensure successful adoption and implementation of Illumina bioinformatics products, platforms, and workflows. • Troubleshoot complex customer complaints related to Illumina's bioinformatics portfolio and other analytical challenges involving genomics data. • Provide customer facing trainings on Illumina’s bioinformatics portfolio and general bioinformatics approaches to analytical challenges. Train and develop AMR support team skillsets in bioinformatics and Illumina software portfolio. • Provide voice of customer feedback to internal groups including marketing and development to improve current and upcoming products. • When needed, travel to customer sites to provide training, troubleshooting, or consultation support for sales or support teams. Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs. Requirements • Typically has a minimum of 5+ years of experience in a similar position including general experience in Life Sciences or Genomics industries.. • Advanced degree in Life Sciences or Computational fields (e.g. Bioinformatics, Computer Sciences, Molecular Biology). Experience in Next Generation Sequencing preferred. • Strong knowledge of genomics, sequencing applications, and methods that apply to Bioinformatics and Illumina technology. Broad interest and knowledge in science and technology in Genomics. • Prior field experience supporting customers in a highly technical field preferred. • Demonstrated expertise and experience with commonly-used data analysis software applications and bioinformatics tools and programs, including those used for Next Generation Sequencing required. Experience with Illumina's bioinformatics portfolio preferred. • Excellent skills in data analysis. Demonstrated experience using bioinformatics or analytics to solve complex scientific or technical challenges. • Fluency in at least one scripting/programming language (e.g. Python, Perl, R, etc.) commonly used in bioinformatics pipelines required. • Linux fluency required, and experience with cloud environments preferred. • Proven ability to resolve complex issues while maintaining positive customer relations and communication. • Exceptional written and verbal communication and excellent presentation and training skills. • Must be willing to travel up to 30% All listed requirements are deemed as essential functions to this position; however, business conditions may require reasonable accommodations for additional task and responsibilities. Concerns regarding COVID-19 continue as positive cases are experienced in the communities in which we operate. Please be aware that, as a condition of employment, Illumina may require proof of COVID vaccination in accordance with local statutory requirements (subject to limited exceptions) beginning November 1, 2021. At Illumina, we strive to foster a diverse and inclusive workplace by cultivating an environment in which everyone contributes to our mission. Built on a strong foundation, Illumina has always been rooted in openness, collaboration, and seeking alternative views and perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and demonstrate our collective commitment to diversity and inclusion in the communities we live and work. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf

Why UT Southwestern? With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued patients and employees. With over 20,000 employees, we are committed to continuing our growth with... the best professionals in the healthcare industry. We invite you to be a part of the UT Southwestern team where you’ll discover teamwork, professionalism, and consistent opportunities for growth. Job Summary The Bioinformatics department is looking to add a Computer Programmer III to the team. This will be a hybrid work model position with time spent working both remotely and on campus. Job Duties • Determines best means of solving complex problems, performing original design analysis for methods of solution. • Utilizes knowledge of systems to assist in defining problems, run requirements, and time and form charts. • Develops general and detailed flow-charts, tables, and diagrams required for programming projects. • Writes programs in appropriate (interpretive, compiler, or assembly) language and documents procedures used throughout each program. • Develops controls and initiates tests to verify system integrity. • Optimizes and improves performance of programs and subsystems. • Coordinates program development with users, advising them and programmers of lower grade relative to use of special programs and techniques. • Provides working supervision to computer programmers and computer programming assistants of lower grade. • Performs other duties as assigned. Experience and Education High school graduation or GED plus successful completion of vocational training in computer programming and five (5) years experience in computer operation and/or programming, including at least one (1) year as Computer Programmer II or equivalent. To learn more about the benefits UT Southwestern offers visit https://www.utsouthwestern.edu/employees/hr-resources/ For COVID-19 vaccine information, applicants should visit https://www.utsouthwestern.edu/covid-19/work-on-campus/ This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. In accordance with federal and state law, the University prohibits unlawful discrimination, including harassment, on the basis of: race; color; religion; national origin; sex; including sexual harassment; age; disability; genetic information; citizenship status; and protected veteran status. In addition, it is UT Southwestern policy to prohibit discrimination on the basis of sexual orientation, gender identity, or gender expression

Description The Salomonis lab within Biomedical Informatics develops new integrative solutions for single-cell and bulk genomics assays with an emphasis on understanding cellular heterogeneity in healthy tissue systems and disease. This includes various computational approaches for single-cell transcriptomics and multimodal analysis. The Bioinformatics Analyst works in close collaboration with... our experimental collaborators on multiple inter-connected projects to identify novel transitional cell-states in stem and progenitor populations, develop computational strategies to isolate cell populations CITE-Seq (single-cell transcriptomes with surface-linked antigen expression), track cells during differentiation, dissect underlying gene regulatory networks using multi-omics and multimodal single-cell approaches, evaluating and improving existing computational approaches and working with a team of analysts and biology domain experts to create new molecular models of development and disease, with an emphasis on immunobiology and cancer. The ideal candidate will have significantly contributed to prior publications, demonstrated "out-of-the-box" thinking, excellent communication skills, demonstrated research independence, and excellent programming experience. REPRESENTATIVE RESPONSIBILITIES • Perform data analysis for research projects: Work collaboratively with research groups for the analysis of single-cell and bulk transcriptome datasets. Perform quality control, sequence alignment, gene and splicing statistical analyses and functional regulatory from next generation sequencing experiments. Integrate datasets across from different patients, disease states and across species. Evaluate the contribution of complex biological or technological covariates from large-scale genomic results (e.g., batch effects, sex). Evaluate results at the gene, pathway and systems-level, integrating detailed biological knowledge at different steps in the analysis. Apply statistical analysis or machine learning analysis methods. Customize data visualization results using existing software toolkits (e.g., R, python). Prepares manuscript materials for publications and reports about research projects for presentation at scientific meetings. • Informatics operation: Applies existing software to support sequence alignment, inter-sample comparison, algorithm evaluation, data management, data retrieval, and web access. Document standard operating procedures based on best practice. Experience working with complex metadata and data/results documentation (provenance). Assists in developing tools to support unsupervised sample and gene heterogeneity analyses. Incorporates institutional resources and 3rd party software into specialized analysis workflows for the team and clients. Helps to maintain computational infrastructure and control the flow of samples and information for studies. Works closely with Biomedical Informatics department to leverage system, software and knowledge efficiencies. • Teamwork: Guides and advises less-experienced staff. Trains and supports staff, residents, fellows, and technologists. Communicate results outside of CCHMC. For specific questions, please contract Dr. Nathan Salomonis at nathan.salomonis@cchmc.org or visit his website: (https://www.cincinnatichildrens.org/research/divisions/b/bmi/labs/salomonis) Qualifications EDUCATION/EXPERIENCE Required: •Master's degree in a related field • 2 - 5 years of work experience in a related job discipline • Experience with diverse genomics data type (RNA-Seq, genome-sequencing, ATAC-Seq) • Experience programming in Python and cluster-compute environments • Background in statistics and/or software development and/or Machine learning/API

Why UT Southwestern? With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care and resources for the community. With a career at UT Southwestern, you will be a key part of our research within the Department of... Bioinformatics with opportunities to be part of the cutting-edge research projects. We invite you to be a part of the UT Southwestern team where you’ll discover a culture of teamwork, professionalism, and a rewarding career! Job Summary The Jeon Lee laboratory at the University of Texas Southwestern Medical Center is welcoming applications for a computational biologist position in multi-omics data analysis. The research focuses on analyzing metabolomics, proteomics, and transcriptomics data, and integrating those analysis results to better understand critical biological processes and to discover biomarkers in order to answer important scientific questions, especially in cancer biology and brain science. Successful applicants will be capable of analyzing mass-spec data, bulk RNA-seq data, and single-cell RNA-seq data, having deep understandings in related statistics and computation algorithms. Job Duties • Manage research laboratory computer hardware and software programming and maintenance. • Ensure existing systems meet the continuing needs of the lab and/or recommend and test new systems as necessary. • Perform complex data analysis related to specialized research methodologies and results as assigned by the PI. • Develop and/or modify software to support new and ongoing research projects. • Resolve hardware, software, and network issues in support of the lab. • Develop and maintain complex databases to support new and ongoing research projects. • Train laboratory staff in the use of pertinent research systems. • May specialize in bioinformatics, software development, network administration, or hardware/software maintenance. • Perform other duties as assigned. Experience and Education • Master’s degree in Computer Science or a related field of biological science. • Bachelor’s degree in Computer Science or a related field of biological science, and two (2) years related research experience in bioinformatics and computational biology. To learn more about the benefits UT Southwestern offers visit https://www.utsouthwestern.edu/employees/hr-resources/ For COVID-19 vaccine information, applicants should visit https://www.utsouthwestern.edu/covid-19/work-on-campus/ This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. In accordance with federal and state law, the University prohibits unlawful discrimination, including harassment, on the basis of: race; color; religion; national origin; sex; including sexual harassment; age; disability; genetic information; citizenship status; and protected veteran status. In addition, it is UT Southwestern policy to prohibit discrimination on the basis of sexual orientation, gender identity, or gender expression

At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and... make a difference. We seek a talented, collaborative inter-disciplinary computational scientist to work on the analysis, statistical modeling and generation of hypotheses from high-dimensional molecular profiling data. This individual will play a key scientific role leveraging innovative computational analysis strategies and rich patient data to empower data-driven decisions alongside BMS colleagues in our Informatics & Predictive Sciences department and in collaboration with internal partners in the translational medicine research team. Analysis scenarios will involve applying cutting-edge bioinformatics, statistics, and data analysis methods; working with clinical and large-scale omics data and biomarker data sets that could include WES, RNA-Seq, scRNAseq, IHC, flow cytometry, ChIP-seq, and ATAC-seq from BMS’s industrial-leading late stage oncology clinical studies; influencing development strategies and advancing BMS late stage oncology pipeline. This position offers the exciting opportunity to make major contributions to scientific knowledge of cancer disease biology, and to directly impact treatment of cancer patients. The position would suit an individual with strong biological and computational capabilities and excellent communication and collaboration skills. Applications are encouraged from those involved in innovative translational research for oncology indications in clinical or industrial research environments. The role offers the opportunity to impact directly the delivery of truly transformational and life-changing therapies in key diseases of unmet medical need. Responsibilities • Perform analysis of epigenomic datasets (e.g., ChIP-seq, ATAC-seq) to inform new target and early pipeline strategies. • Perform analysis of clinical and biomarker datasets (e.g., large-scale -omics datasets including RNASeq, and Whole Exome/Genome Sequencing) and derive clinically meaningful interpretations. • Identify potential biomarkers for patient enrichment strategies and gain mechanistic insights of responses and resistances to treatments of interest. • Summarize analysis results and report conclusions to BMS decision-making bodies; help communicate conclusions to regulatory agencies and the broad scientific communities. • Evaluate and adapt latest scientific findings and methods into bioinformatics analysis plans. Qualifications: • Ph.D. with 2+ years of experience in computational biology, bioinformatics, statistics or related fields. • Experience in biotech or pharmaceutical industries is a plus. • Strong experience in the use of a high-level programming language such as R, MATLAB, Python or Perl for complex data analysis and reproducible research practices. • Experience with epigenomic datasets including ChIP-seq and ATAC-seq. • Experience working with a variety of Next Generation Sequencing datasets, including Whole-Genome, Whole-Exome Sequencing. • Deep understanding of disease biology in oncology. • Familiarity with contemporary cloud and high-performance computing environments. • Expertise in application of contemporary machine-learning/AI approaches. • Ability to work both independently and collaboratively, and to handle several concurrent, fast-paced projects while conforming with rigorous requirements of clinical studies. • Strong problem-solving and collaboration skills, rigorous and creative thinking. • Excellent communication, data presentation, and visualization skills. • Fluent written and verbal English language communication. Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture. To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S. Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations

The Knowledge Systems Group (KSG) at Dana-Farber Cancer Institute is seeking an experienced Bioinformatics Data Manager to spearhead multiple bioinformatics “big data” projects. The role is primarily focused on making standardized genomic and clinical data sets available to the scientific community via open-access, open-source platforms. The Knowledge Systems Group (KSG) is an applied... bioinformatics group focused on developing open-source platforms for cancer genomics research and precision cancer medicine. We are computational biologists, software engineers, and project managers, all united in using our skills to make a difference in cancer patients' lives. We support several projects, including the NCI Human Tumor Atlas Network (HTAN), the Cancer Immunologic Data Commons (CIDC), and the cBioPortal for Cancer Genomics. We also support DFCI’s institutional clinical sequencing and precision cancer medicine initiatives. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. As the Bioinformatics Data Manager, you will be responsible for: • Consulting with external stakeholders to understand and define consortium requirements regarding data access, data analysis, and data sharing. • Understanding new genomic assays and defining new data standards. • Understanding and defining clinical data standards, and creating clinical data mappings for harmonized clinical data sets. • Translating consortium requirements into well-defined project specifications for handoff to software engineering team. • Integrating and harmonizing data sets in preparation for cross-trial and cross-cancer analysis. • Working with data producers and ensuring the transfer of new, standardized data sets into cloud-based data sharing platforms. • Strong background and interest in cancer genomics. • Strong background and interest in open access science. • MS or PhD in bioinformatics or computational biology. • Experience developing genomic and clinical data standards and ontologies. • Experience managing genomic assay data, including single cell RNASeq and multiplex imaging. • Experience managing complex bioinformatics projects, including stakeholder management, and ability to multitask multiple project deadlines. • Working experience with data sharing platforms, including dbGAP or NCI Cloud Resources. Due to COVID-19, KSG is currently in hybrid mode, with most members working remotely, but some members working on site 2-3 days / week. For this position, we are open to remote/hybrid workers in Massachusetts, New Hampshire or Rhode Island. At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply

Company This is a great opportunity for a Senior Bioinformatics Scientist to join a pioneering scale-up biotech company, that has developed their own unique Cloud Data platform which organizes and parses the deluge of new biology data, enabling to triangulate insights across genomics, epigenomics, transcriptomics, proteomics, and beyond... Role • Lead the development of new bioinformatics workflows, including, but not limited to: whole genome/exome sequencing, RNAseq (single-cell, bulk, spatial), ChIP-Seq, ATAC-seq (single-cell and bulk), proteomics, and metabolomics. • Collaborate with our full-stack engineering team on making these workflows efficient and performant. • Engage directly with customers (both biologists and Bioinformatician) on their deployment of the company's platform, ensure the technical success of client engagements, and communicate customer feedback and feature requests to the broader team. Requirements: • PhD in Bioinformatics, Computational Biology, Statistics Biology, or other relevant scientific field. • Experience analyzing gene editing sequencing data (GUIDE-seq, Circle-Seq, any kind of CRISPR/TALEN/ZNF off-target seq etc) • Ability to analyze integration pattern and rare events • Expertise in NGS (RNAseq/WGS/WES) • Experience with both Illumina and long (PacBio/Nanopore) reads a.ofosu@x4lifesciences.com Equal Opportunity Employer/Disability/Veterans

Overview Senior Bioinformatics Scientist... This position is eligible for a $3,500 Sign On Bonus for external candidates. Our team at The Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital is driven to create a future where no child with genetic disease goes undiagnosed and every child with cancer receives optimal treatment based upon their personal genome sequence. Recognizing that the root cause of many childhood diseases can be traced directly to the genome, our research program focuses on the development of novel technologies to analyze the billions of data points with a patient’s genome. We are looking for a Senior Bioinformatics Scientist to join the IGM Computational Genomics Group who shares our passion to advance the understanding of disease through the development of computational tools and the application of big data technologies. You will have the opportunity to work collaboratively within a dynamic team of bioinformaticians, data scientists, and software engineers developing novel computational and statistical approaches for the analysis and interpretation of genomic data. Why Nationwide Children's Hospital? The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children’s Hospital, where Passion Meets Purpose. Here, Everyone Matters. We’re 14,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we’ll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Cultureto deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children’s badge what they do for a living. They’ll tell you it’s More Than a Job. It’s a calling. It’s a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children’s Hospital. A Place to Be Proud Responsibilities PRINCIPAL DUTIES AND RESPONSIBILITIES Our ideal candidate will have experience in computational approaches for genomic data analysis, including bioinformatics, data analytics and machine learning. You will primarily focus on the application of your skills to our research programs that study pediatric cancer, congenital heart defects and cardiovascular diseases, birth defects, and rare genetic diseases in collaboration with our research and clinical faculty. As a Senior Bioinformatics Scientist, you will have the opportunity to develop and drive independent computational genomics research projects, driven by your interests and skills. As we scale genome sequencing to thousands of patients, we are particularly interested in the application of artificial intelligence to the discovery and interpretation of genetic variation relevant to disease. This position is part of a distributed team that on occasion will need to come to the NCH main campus for meetings. The option for remote, hybrid or full-time on-site is available. Qualifications Education • PhD. in Bioinformatics or a related field with a focus on 'Omics'-based bioinformatics preferred • Minimum two years of postdoctoral experience or five years professional experience in computational biology or bioinformatics Responsibilities • Conduct research, development and evaluation of computational approaches to advance our understanding of pediatric disease • Perform next generation sequencing data analysis, interpretation and visualization • Based upon your experience and identifying an area you are passionate about, take a lead role in our translational research protocols or computational genomics research areas • Communicate findings to clinicians and researchers, author journal publications and present at professional meetings • Assist in supervision and training of junior bioinformatics scientists, analysts and trainees at the graduate and postdoctoral level Skills & Attributes • Fluency in programming and scripting languages is required (e.g., R, Python, etc.) and their use in LINUX and cloud computing environments • Expert knowledge of integrative -omics analysis, genomic data analysis (i.e. DNA-Seq, RNA-Seq, ChIP-Seq, etc), data mining, complex data analysis and statistics • Excellent interpersonal and communication skills and the ability to manage multiple projects while maintaining a high level of attention to detail Experience • Confident with the use of bioinformatics tools and databases, approaches to statistical analysis and data visualization methods • Strong understanding of molecular biology and genomics • Experience in algorithm development or machine learning approaches • Proven record of applying or developing computational biology approaches to generate and test new hypotheses • Must be a team player with a history of conducting collaborative and self-directed research within broader goals set by the group MINIMUM PHYSICAL REQUIREMENTS • Sitting – Frequently Talking on phone/in person – Frequently Typing on a keyboard – Constantly Standing/walking – Frequently Physically Active – Occasionally • The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. EOE M/F/Disability/Vet

Overview Senior Bioinformatics Scientist... This position is eligible for a $3,500 Sign On Bonus for external candidates. Our team at The Institute for Genomic Medicine (IGM) at Nationwide Children's Hospital is driven to create a future where no child with genetic disease goes undiagnosed and every child with cancer receives optimal treatment based upon their personal genome sequence. Recognizing that the root cause of many childhood diseases can be traced directly to the genome, our research program focuses on the development of novel technologies to analyze the billions of data points with a patient's genome. We are looking for a Senior Bioinformatics Scientist to join the IGM Computational Genomics Group who shares our passion to advance the understanding of disease through the development of computational tools and the application of big data technologies. You will have the opportunity to work collaboratively within a dynamic team of bioinformaticians, data scientists, and software engineers developing novel computational and statistical approaches for the analysis and interpretation of genomic data. Why Nationwide Children's Hospital? The moment you walk through our doors, you can feel it. When you meet one of our patient families, you believe it. And when you talk with anyone who works here, you want to be part of it, too. Welcome to Nationwide Children's Hospital, where Passion Meets Purpose. Here, Everyone Matters. We're 14,000 strong. And it takes every single one of us to improve the lives of the kids we care for, and the kids from around the world we'll never even meet. Kids who are living healthier, fuller lives because of the knowledge we share. We know it takes a Collaborative Culture to deliver on our promise to provide the very best, innovative care and to foster new discoveries, made possible by the most groundbreaking research. Anywhere. Ask anyone with a Nationwide Children's badge what they do for a living. They'll tell you it's More Than a Job. It's a calling. It's a chance to use and grow your talent to make an impact that truly matters. Because here, we exist simply to help children everywhere. Nationwide Children's Hospital. A Place to Be Proud Responsibilities PRINCIPAL DUTIES AND RESPONSIBILITIES Our ideal candidate will have experience in computational approaches for genomic data analysis, including bioinformatics, data analytics and machine learning. You will primarily focus on the application of your skills to our research programs that study pediatric cancer, congenital heart defects and cardiovascular diseases, birth defects, and rare genetic diseases in collaboration with our research and clinical faculty. As a Senior Bioinformatics Scientist, you will have the opportunity to develop and drive independent computational genomics research projects, driven by your interests and skills. As we scale genome sequencing to thousands of patients, we are particularly interested in the application of artificial intelligence to the discovery and interpretation of genetic variation relevant to disease. This position is part of a distributed team that on occasion will need to come to the NCH main campus for meetings. The option for remote, hybrid or full-time on-site is available. Qualifications Education • PhD. in Bioinformatics or a related field with a focus on 'Omics'-based bioinformatics preferred • Minimum two years of postdoctoral experience or five years professional experience in computational biology or bioinformatics Responsibilities • Conduct research, development and evaluation of computational approaches to advance our understanding of pediatric disease • Perform next generation sequencing data analysis, interpretation and visualization • Based upon your experience and identifying an area you are passionate about, take a lead role in our translational research protocols or computational genomics research areas • Communicate findings to clinicians and researchers, author journal publications and present at professional meetings • Assist in supervision and training of junior bioinformatics scientists, analysts and trainees at the graduate and postdoctoral level Skills & Attributes • Fluency in programming and scripting languages is required (e.g., R, Python, etc.) and their use in LINUX and cloud computing environments • Expert knowledge of integrative -omics analysis, genomic data analysis (i.e. DNA-Seq, RNA-Seq, ChIP-Seq, etc), data mining, complex data analysis and statistics • Excellent interpersonal and communication skills and the ability to manage multiple projects while maintaining a high level of attention to detail Experience • Confident with the use of bioinformatics tools and databases, approaches to statistical analysis and data visualization methods • Strong understanding of molecular biology and genomics • Experience in algorithm development or machine learning approaches • Proven record of applying or developing computational biology approaches to generate and test new hypotheses • Must be a team player with a history of conducting collaborative and self-directed research within broader goals set by the group MINIMUM PHYSICAL REQUIREMENTS • Sitting - Frequently Talking on phone/in person - Frequently Typing on a keyboard - Constantly Standing/walking - Frequently Physically Active - Occasionally • The above list of duties is intended to describe the general nature and level of work performed by individuals assigned to this classification. EOE M/F/Disability/Vet Employment Type: OTHER