Bioinformatics Jobs

Twist is looking for a Bioinformatics Scientist to join our Production Bioinformatics Team. You will work alongside research scientists, software engineers and data scientists to further deliver on our mission to expand access to best-in-class synthetic biology and next-generation sequencing applications. You will be developing and engineering tools to better evaluate and build hardened... production quality pipelines, optimize data quality, and automate lab and bioinformatics processes. Our ideal candidate is an organized problem solver with a background in developing and building novel production-quality bioinformatics tools and packages. Equally excellent communication skills and a proven ability to work independently are required. Responsibilities • Collaborate with R&D and Field Application Scientists to develop, build, and validate bioinformatics tools starting from proof-of-concept to production-grade software. • Apply scientific and engineering best practices to update and transition bioinformatics algorithms and pipelines from Research to Production • Work closely with synthetic biology groups to develop and implement novel design algorithms and QC methods and tools • Maintain production bioinformatics tools and workflows through their lifecycle Required Skills And Experience • PhD or equivalent in Bioinformatics, Computer Science, Engineering, or another science with minimum of 2 years of industry experience • Proven ability to conceptualize, develop, and validate novel NGS design and QC methods based on established bioinformatics algorithms (eg. alignment, variant calling, de novo assembly, etc) and tools (eg. bwa, GATK, Picard, SPAdes etc) • Strong proficiency with Python, SQL, Bash, and Git with experience building packages with tests as well as strong written and verbal English communication skills • Experience with working in industry Production environment including validation and documentation • Able to effectively communicate and work remotely with teams using Slack, JIRA and Confluence • Ability to troubleshoot complex issues quickly and effectively Preferred • Excellent understanding of molecular biology, with an emphasis on DNA chemistry • Experience with synthetic biology design and/or QC • Experience working with Illumina sequencers, chemistry, and software • Experience with AWS, Docker, Airflow and Kubernetes • Experience with data science tools (Pandas, Spark) • Experience with Rust nice to have About Twist Bioscience Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA. At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers. Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law

Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry, by making genetic testing affordable and accessible for everyone to guide health decisions across all stages of life. Our development... team works on a variety of projects ranging from innovations in healthcare systems to taming the chaos of biology. We are constantly improving our tools and technologies to deliver the highest quality actionable information to doctors and patients. Behind every sample that comes in through the door we know there is an individual and a family looking for answers. What you’ll do: • Architect and implement high throughput genomics pipelines using modern technologies, optimizing for robustness, scale, and for being deployed at labs around the world • Maintain, improve, and create new pipelines to support our ever-expanding catalog of production bioinformatics pipelines • Implement and evangelize software engineering best practices • Collaborate closely with bioinformaticians, molecular biologists, dev ops and software engineers What you bring: • Experience in analysis pipeline development, with a preference for high throughput genomics workflows (especially Illumina and PacBio sequencing and arrays) • Experience in contributing to large, shared software repositories. Python knowledge required • Passion about writing clean, reusable, and composable pipelines • Experience with High-Performance Computing (HPC) environments (e.g. S/UGE, LSF, and/or Amazon AWS) • Experience with Distributed Workflow managers, e.g.NextFlow, airflow, luigi, • Capability to lead technical efforts and create clarity around ambiguous requirements • Excellent communication (written and verbal) and data presentation skills • Preferred: Experience using and designing RESTful and RPC-style interfaces • Preferred: Experience with Docker or other containerization/virtualization • Preferred: Experience with CI/CD At Invitae, you’ll work alongside some of the world’s experts in genetics and healthcare at the forefront of genetic medicine. Our teams thrive in our dynamic organization, which has been designed to empower them to make the biggest impact they can for our patients. We give our employees the ability to explore interests and capabilities broadly within the organization. We prize freedom with accountability and offer significant flexibility. We also provide excellent benefits and competitive compensation in a fast-growing organization. At Invitae, we’re changing healthcare to change lives. Join us. At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance. #LI-Remote #LI-JM1

The Position Bioinformatics Cloud Software Engineer... Genentech seeks a talented and highly motivated Software Engineer to develop a cloud based genomic analysis system in support of our Translational Genomics efforts. Our Translational Genomics efforts span the interface of human genetics, functional genomics, molecular biology, disease model engineering, tissue and cellular profiling, and advanced computational methodology. The primary focus of this position is to extend our existing orchestration system for large scale genomic analysis workflows into the cloud to enable Genentech researchers to scale the throughput of their genomic and genetic analyses as needed. Solutions will need to integrate cloud native concepts with microservice based components in an existing software ecosystem. A successful candidate will collaborate with interdisciplinary teams of Software Engineers, DevOps engineers and Computational Biology Scientists to design and implement cloud native software solutions with an emphasis on service-oriented architecture and containerized workflows. The work includes requirements gathering, design and architecture, as well as backend and frontend development. The candidate will use best practices of continuous integration and software delivery to accommodate the fast pace of innovation in Genentech Research. Successful candidates will meet many of the following requirements • You have a Masters degree or equivalent in Software Engineering, Computer Science, Bioinformatics, or similar and 6-10 years of relevant experience in an academic or commercial setting. • You have successfully planned and implemented multiple software projects throughout the whole development cycle (planning, implementation, testing, release, maintenance) following modern software development practices. • You are a full-stack software developer (backend+frontend) that if needed maintains its own dev-ops tool chain, but plays well with enterprise level solutions. • You are able to break down large problems into smaller microservice based components and can develop them independently or as part of a large team. • You have experience with cloud related concepts such as deployment via Kubernetes or AWS cloud formation, Monitoring and containerization. • Experiences and expertise with cloud related concepts such as building infrastructure using Terraform, AWS Cloud Formation, AWS Batch, Lambda and Code Pipeline is a must - an AWS certification on an associate level is a plus. • You have architected distributed systems with infrastructure automation, monitoring and alerting and you are familiar with troubleshooting distributed systems. • You have a focus on high-quality code, including automated testing and coding best practices and you are able to prepare and conduct code reviews. • You have experience with relational and non-relational DB technologies. Knowledge of other search, messaging and queuing technologies such as ElasticSearch, SOLR, RabbitMQ and Kafka are desirable. • You are a quick learner and your analytical skills help you to effectively translate technical and scientific process requirements into a software product. • You have strong experience in the use of a high-level, object oriented programming language such as Python, Go or Java and a strong understanding of Linux/Unix. • You are comfortable working both independently and collaboratively, and with handling several concurrent, fast-paced projects. • You are able to execute technical projects at global scale, across multiple teams and time zones. Strategic, analytical mindset and ability to innovate using technology to advance business goals. • Experience in managing data according to FAIR principles as well as tracking data lineage, ensuring data quality and improving data discovery is a plus. • You have strong communication skills and can untangle and discuss complex technical tasks. • Prior experience in a life science or drug development environment are beneficial. What to expect from us • A highly collaborative and dynamic research environment where we aim to advance the rate of scientific discovery using purposefully built solutions. • Access to large data sets, samples and compute resources. • Access to state-of-the-art technologies and pioneering research. • Participation in seminar series featuring academic and industry scientists. • Campus-like lifestyle with a healthy work-life balance. • Mentored opportunities to further develop professional skills. Who we are A member of the Roche Group, Genentech has been at the forefront of the biotechnology industry for more than 40 years, using human genetic information to develop novel medicines for serious and life-threatening diseases. We are a research-driven biotechnology company, whose medical innovations for cancer and other serious illnesses make a difference for patients across the globe. Please take this opportunity to learn about Genentech where we believe that our employees are our most important asset & are dedicated to remaining a great place to work. Genentech is an equal opportunity employer & prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital & veteran status. For more information about equal employment opportunity, visit our Genentech Careers page

About Ancestry: When you join Ancestry, you join a human-centered company where every person’s story is important. We believe that by discovering the struggles and triumphs of our past, we can foster deeper bonds and more meaningful connections among families and communities. Our talented team of scientists, engineers, genealogists, historians, and storytellers is dedicated to empowering... customers around the world from all backgrounds on their journeys of personal discovery. With more than 30+ billion digitized global historical records, 100+ million family trees, and 20+ million people in our growing AncestryDNA database, Ancestry helps customers discover their family story and gain a new level of understanding about their lives. Passionate about dedicating your work to enriching people’s lives? You belong at Ancestry. AncestryDNA is looking for an experienced bioinformatician who has deep AWS domain expertise and is an experienced infrastructure DevOps Engineer to lead our R&D Bioinformatics team and efforts. You will contribute as part of our DNA Science team, which includes data scientists, computational biologists, and population geneticists working at the forefront of combining our 20+ million sample genomics dataset with our vast collection of family history records and trees to empower the development of new methods and the creation of new insights into the histories of the human family. You will be reporting to the Director, Research and Bioinformatics. What You Will Do: • You will lead the DNA Science bioinformatics team with 2 direct reports • You will work independently and with other Engineering teams to develop tools on AWS for research • You will support the DNA Science research team by coordinating access to multiple datasets, ensuring the highest standards of privacy and security • You will be part of the team responsible for developing and operating the cloud environment that supports the research team. • You will collaborate across the organization to identify opportunities to change, improve the customer experience, and achieve departmental goals • You will be an organizational expert on AWS best practices and support learning and development of the DNA Science and DNA Engineering team Who You Are: • You will have a Masters in computer science, bioinformatics, or a related field. • Minimum 5 years of post-education experience working with cloud-based research infrastructure. • Knowledge of core Cloud Computing concepts and advanced-level experience with AWS is required. • Advanced knowledge of Linux (including system administration) and Python programming. • Experience managing teams. • Experience with CI/CD (e.g. Jenkins), IAC (e.g. Terraform), Workflow-based distributed scientific analysis pipelines (e.g. Snakemake), network file system (e.g. Gluster), and job managers (e.g. Slurm) • Knowledge of storage performance concepts (iops, throughput, and performance bottlenecks) • Experience working with distributed computing tools (Hadoop, Hive, Spark) Additional Information: Ancestry is an Equal Opportunity Employer that makes employment decisions without regard to race, color, religious creed, national origin, ancestry, sex, pregnancy, sexual orientation, gender, gender identity, gender expression, age, mental or physical disability, medical condition, military or veteran status, citizenship, marital status, genetic information, or any other characteristic protected by applicable law. In addition, Ancestry will provide reasonable accommodations for qualified individuals with disabilities. All job offers are contingent on a background check screen that complies with applicable law. For San Francisco office candidates, pursuant to the San Francisco Fair Chance Ordinance, Ancestry will consider for employment qualified applicants with arrest and conviction records. Ancestry is not accepting unsolicited assistance from search firms for this employment opportunity. All resumes submitted by search firms to any employee at Ancestry via-email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Ancestry. No fee will be paid in the event the candidate is hired by Ancestry as a result of the referral or through other means

The Position At Roche, 94,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity, and diversity. We believe every employee makes a difference. We are passionate about transforming patients’ lives. We are courageous in both decision and... action, we believe that good business means a better world. This position is part of the Individualized Medicines Team in Pharma Cell and Gene Therapy Group (PTC) responsible for the process development, manufacture and supply of personalized immunotherapies in collaboration with our global partners. We are seeking a highly motivated team member to contribute to the ongoing effort to evaluate and operationalize NGS and bioinformatics aspects of individualized medicine manufacturing. You will conduct bioinformatics analysis to support ongoing process development, refinement of the analysis pipelines and clinical manufacturing operations. The successful candidate is expected to effectively communicate and develop collaborative relationships with key stakeholders. Once a strategic framework for future manufacturing is in place, you will play a critical role in process development/implementation to enable commercial manufacturing of next generation therapeutics. Responsibilities • You will provide bioinformatics support to ongoing NGS process and assay development activities for individualized therapies. • You will collaborate with internal and external stakeholders to develop process understanding of existing pipelines and algorithms. • You will provide computational/bioinformatics support as needed across the broader PTC community. • You will author technical and validation reports for bioinformatics and assay development activities. • You will provide strategic and operational support needed for bioinformatics functions within Genentech’s individualized medicines program and broader PTC. • You will play a critical role in enabling a new manufacturing paradigm for Roche/Genentech that includes next-generation sequencing and advanced bioinformatics techniques to deliver individualized immunotherapeutics to patients. Qualifications The ideal candidate will meet the following qualifications: • Ph.D or MS in bioinformatics or a related discipline. 3+ years industry experience in bioinformatics analysis. • Expertise coding in Python, R or Matlab and using version control (git, svn) • Previous experience using and developing bioinformatics pipelines for NGS data analysis (WES, WGS, RNAseq, scRNASeq, amplicon seq etc), including profiling accuracy of tools/algorithms. • Experience authoring technical documentation, in collaboration with diverse stakeholders. • Previous experience building pipelines/algorithms supporting NGS assay development is a plus. • Experience working with third generation sequencing data (Nanopore, Pacbio) is a plus. • Prior experience in bioinformatics aspects of cancer immunology is a plus. • Must be detail-oriented with excellent collaborative and organizational skills in order to manage multiple projects and meet assigned deliverables. • Strong written and verbal communication skills and ability to effectively communicate with cross-functional teams. • Strategic agility and ability to adapt to the evolving personalized healthcare environment. • Comfortable working in a flexible, fast-paced team environment #ptcareers

About Mission Bio Mission Bio is a high-growth, well-funded Series C company based in South San Francisco, California. Our mission is to enable our customers to eradicate cancer. We do so with our innovative microfluidic system that is the leader in the high throughput single cell, multi-omics space that is used by major cancer centers and pharma / biopharma companies globally to better... characterize cancer as well as providing solutions to accelerate therapeutic development, such as the future standard of care in cell and gene therapy. We are a dynamic and diverse team. We live by the culture of “One Cell One Team One Vision”. We are collaborative, we are driven, and we are curious. Field Bioinformatics Specialist - US The Field Bioinformatics Specialist (FBS), preferably based in the larger San Francisco Bay Area will provide support by assisting scientists and researchers to analyze data sets. The job goes beyond typical database programming, as you must demonstrate experience and capability in chemistry, biology, or other life sciences. As a key member of the Team, you will also assist in the development and improvement of key commercial processes to ensure that Mission Bio provides customers with world class support. The position is a multifunctional leadership role that will help in driving Mission Bio’s efforts into research, biopharma, and clinical segments. The position will be responsible for the development, maintenance and provision of bioinformatics and applications support and training on Mission Bio’s product portfolio, thereby contributing to rapid platform/application adoption and customer satisfaction. The ideal candidate will have molecular biology experience and has worked as part of a multi-disciplinary team encompassing the whole experimental cycle from sample collection to analysis. Previous industry experience in the role is desired. Duties and Responsibilities: • Provide high quality, effective informatics support to customers and prospective customers in territories through knowledge of Mission Bio’s products (expertise around variant calling and single-cell research preferred) and effective communication of applications related to these products. • Communicate research results through conference presentations, scientific publications, or project reports. • Coding experience in Python • Familiar with Linux based operating systems • Consult with researchers to analyze problems, recommend technology-based solutions, or determine computational strategies. • Advise others on the development or use of new technologies. • Analyze large molecular datasets such as genomic sequence data, and proteomics data for clinical or basic research purposes. • Keep abreast of new biochemistries, instrumentation, or software by reading scientific literature and attending professional conferences. • Confer with departments such as marketing, business development, and operations to coordinate product development or improvement. • Collaborate with software developers in the development and modification of commercial bioinformatics software. • Participate in the organization and running of meetings, seminars, and training courses. • Actively participate in the development and support of strong relationships with customers collaborating with the Field Application Scientists. • Establish and maintain strong, positive, productive relationships with customer accounts. • Be a liaison in conjunction with Support Leadership and Sales to Marketing, R&D, and Bioinformatics departments pertaining to the current needs of the defined market segments identified through VOC experience. • Coach, mentor and develop incoming team members within the Support and Application departments including overseeing new employee onboarding. • Be a leader within the Support/Sales organization by proactively and independently addressing customer and product/applications concerns via active participation in routine cross-functional team communications. • Some travel may be required (up to 30%). Required Skills: • Previous experience giving oral presentations, teaching, or training other scientists. • Proven ability of effective written and verbal communication and listening skills. • Strong interpersonal skills and the ability to effectively communicate and project both during face to face and telephone interactions. • Strong proven commitment to customer service and satisfaction, the ability to effectively work on and manage many priorities at one time with excellent troubleshooting, writing, and editing skills. • Demonstrated success working in a fast-paced, dynamic environment. • Ability to work independently and as part of a team towards corporate goals. • Based in the United States, preferably in the larger San Francisco Bay Area. Education and Experience: • Bachelor’s in Molecular Biology with 3 years of related field or a related field required, MS or PhD strongly preferred. • You should have a minimum of three years of lab or relevant experience with proven knowledge and understanding of molecular biology (NGS), cancer biology/oncology, informatics, and related fields. • Bioinformatics experience with an NGS company or relevant industry is desired but not essential. Employee Perks: • Comprehensive Benefits: We offer medical, dental and vision insurance, pre-tax commuter options and a 401(k) plan for all US employees. • Flexible working hours: We offer unlimited vacation for you to take the time you need to recharge and be your most productive self at work. • Training and professional development: Your manager will work with you to define objectives for your professional development and help you progress in your field. Mission Bio is an equal opportunity employer. We welcome and encourage diversity in the workplace regardless of race, gender, sexual orientation, gender identity, disability or veteran status or any other characteristic protected by federal, state or local laws. Mission Bio is an equal opportunity employer. We welcome and encourage diversity in the workplace regardless of race, gender, sexual orientation, gender identity, disability or veteran status or any other characteristic protected by federal, state or local laws

Are you craving an environment to join a group of experienced entrepreneurs creating the next big thing? This fast-paced bio-tech start-up is developing state-of-the-art technology to transform oncology's early detection and treatment in the Bay Area. Should you have a strong background in statistics/applied math and be looking to make a more significant impact, reach out here! THE ROLE... As the Senior Bioinformatics Data Scientist, your responsibilities will include: • Developing methods/algorithms for the analysis of proprietary biological data sets • Building statistical packages and graphical applications for quality control and analysis purposes • Proposing new statistical modelling techniques to further the team's capabilities YOUR SKILLS AND EXPERIENCES: The successful Senior Bioinformatics Data Scientist will have the following skills and experience: • PhD.D. in Statistics, Bio-statistics, Applied Math, etc. • Substantial algorithm/method development experience • Expertise with R developing statistical packages (R Shiny a plus) • Prior work with sequencing or micro-array data sets • Cloud exposure is highly desirable THE BENEFITS: • Generous Salary: $140,000-$160,000 Base Salary • Target Bonus Structure • Equity in a fast-growing start-up • Comprehensive benefits package • Employer-Sponsored 401k • And much more! HOW TO APPLY: Please register your interest by sending your CV to Jocelyne Rojas via the Apply link on this page

An opportunity to work with a cutting edge platform that enables AI-driven, bio simulations that de-risk drug research and development decisions by predicating the clinical outcomes of new drugs before human trials. This Jobot Job is hosted by Avery Warwick... Are you a fit? Easy Apply now by clicking the "Apply" button and sending us your resume. Salary $120,000 - $150,000 per year A Bit About Us Based in San Francisco, CA our company provides pharmaceutical scientists a competitive advantage to accelerate research and development decisions to bring personalized drugs. help us build this future. Our mission to increase human life expectancy through intelligence driven biosystem simulations to truly personalize patient treatment. We are looking for a Sr. Machine Learning/AI Scientist to join our growing team! Why join us? • Competitive Salary! • Great Benefits Package! • The Opportunity to Join an Amazing Team! Job Details We are currently seeking a highly motivated and team-oriented candidate for the position of Bioinformatics Scientist, with expertise in multi-omics data signaling and biological network analysis and applications in the drug discovery and development field. The successful candidate will be working in translational sciences team covering the main aspects of, but not limited to, multi-omics analysis of biomarkers and pathways with AI/ML platform integration for drug PD and efficacy parameterization, descriptor development, and patient stratification facilitating identification and elaboration of different modalities in various therapeutic areas. Responsibilities Contribute to the development and testing of novel and traditional bioinformatics tools to analyze potential pathways and associated networks from drug-target engagement in the context of multi-omics outcomes Contribute to the development of multi-omics driven models for the collection, extraction, analysis, presentation, or tracking of data related to disease pathways, potential therapeutic targets, and drug pharmacodynamics. Use bioinformatics approaches for the development of the research strategy dedicated to the discovery and development of the new pharmaceutics for internal projects as well as in collaboration with private and federal organizations. Perform computational research data analysis and interpret results. Use scripting languages (R, Python, SQL, etc) to retrieve relevant data from various bioinformatics databases; write custom scripts to analyze public or proprietary data. Build computable phenotypes for disease, drug effects, and other conditions using combinations of EHR data and survey data Interpret and visualize results from data aggregation to statistical analysis. Communicate findings in a clear and logical manner to help the Translational Science team make scientific decisions based on the multi-omics outcomes. Considerable periods of time may be spent concentrating and or analyzing data. Education/Experience Ph.D. in Bioinformatics, Computer Science, Biostatistics, Computational Biology, Life Science, or related technical field. Postdoctoral experience in bioinformatics Experience in the Pharmaceutical or Biotech industry is a plus Experience in performing research work and analysis of the -omics data, in particular, transcriptomics datasets. Solid understanding of next-generation sequencing, genomics technologies, and applications, ability to broaden knowledge to adjacent products. Demonstrated ability to successfully use database language for queries (e.g., SQL). It would be a big plus to have Knowledge and experience with PCR assay oligo design. Experience implementing machine learning models. Knowledge, Skills, Abilities Knowledge of molecular biology fields, NGS, omics analysis. Excellent data analysis skills and working knowledge of statistical methods Expertise in scripting language – R and/or Python Ability to work well in a fast-paced startup environment, delivering high-quality results under tight timelines Ability to prioritize and drive results with a high emphasis on quality. Ability to synthesize high-level concepts, drive projects forward, while maintaining attention to detail Excellent critical thinking and skills with proven scientific expertise in biological pathways and bioinformatic techniques. Strong team player the ability to work together with your team as well as cross-functionally and even across institutions, to accomplish your goals. Interested in hearing more? Easy Apply now by clicking the "Apply" button

The Position The Position... Studying microorganisms in intricate, multicomponent communities was revolutionized by multiple ‘omics technologies. We aim to leverage next generation sequencing, metabolomics, and proteomic analyses to dissect how the microbiome, the complex microbial consortium that resides in and on humans, contributes to health and disease. The Departments of Infectious Diseases and Bioinformatics at Genentech seek a talented and highly-motivated Computational Researcher who will be responsible for projects aimed at determining the mechanisms driving host-microbe interactions within the human gastrointestinal tract in multiple therapeutic areas. This is an exciting opportunity for a computationally-minded investigator to utilize clinical trial and primary ‘omics data at the intersection of microbiology, immunology, and genetics to inform the discovery of novel treatments for patients. The responsibilities of this position include: • Analyzing and interpreting microbiome whole metagenomic sequencing and transcriptome data and integrating these insights with metabolomic and proteomic data sets in collaboration with the Infectious Diseases Department as well as other therapeutic areas at Genentech • Using computational approaches to interrogate host-microbe interactions in healthy versus diseased patients alongside disease area experts • Presenting analyses to the cross-functional project teams Qualifications • PhD or MS in Computational Biology or Bioinformatics; or in Microbiology, Immunology, or a related field with a demonstrated expertise in the use of computational approaches • Computational Biologist who explores complex biological questions, writes code (R and/or Python preferred), and analyzes data • Motivated to collaborate with scientists from multiple disciplines, and excited to work on a cross-functional team • Excellent written and verbal communication skills; can present to both computational and non-computational colleagues in large and small groups • Understands and can explain the basic statistical principles and best practices for large-scale, high-dimensional data analysis • Fluent in modern Linux, HPC, and cloud environments; R/RStudio or Python/pandas for data analysis, visualization, and statistics; and source control tools such as GitHub/Bitbucket What to expect from us • Highly dynamic, collaborative, cross-functional research teams that aim to discover new therapeutics to help patients • Leverage data and insight from multiple sources, ranging from basic biology experimentation through patient clinical samples • State-of-the-art technologies and cutting-edge experimental approaches to drive our best-in-class research programs • Interface with academic and industry leaders through seminar series and research collaborations • Work hard and play hard to achieve a healthy work-life balance • Focus on honing professional skills and career development

ROLE DESCRIPTION – Bioinformatics Scientist Scale Biosciences (ScaleBio) is an early-stage life sciences technology company developing the next generation of single cell sequencing and analysis solutions. We are developing our patented split-pool barcoding and... combinatorial indexing technology and methods to enable single cell analysis at unprecedented scale for a broad range of applications across basic, translational, and clinical research. As a Bioinformatics Scientist you will be a technical expert in single cell data analysis within a multi-disciplinary team. We are looking for someone excited to take a new technology all the way to a suite of products; from analysis of early internal prototypes to external software that can scale to unprecedented numbers of samples and cells. Responsibilities • Design and implement analysis software for ScaleBio single cell methods • Work in an interdisciplinary team on novel single-cell assays and advance product development • Develop algorithms, models, and visualizations for huge multi-model single-cell datasets • Engage with external collaborators on the validation of new products and novel applications for very high- throughput single-cell technologies • Identify creative solutions to problems and actively participate in improving methods from the lab, through analysis to the final application. • Present projects and results to the team, customers, and the wider scientific community Experience • Advanced degree in computational biology, computer science, or related discipline; or a minimum of 4 years professional experience with genomic technology • Experience analyzing complex sequencing datasets, including gene expression or epigenetics • A track record of designing and implementing novel algorithms and analysis workflows • Experience developing software, both in scripting and compiled languages • Background in statistical and machine-learning methods for large datasets • Demonstrated ability to become an expert in new fields and work with interdisciplinary teams. • Excellent verbal/written communication and interpersonal skills, with scientist and non-scientists. Preferred Skills and Experience • Experience with single-cell sequencing technology and analysis methods • Experience with professional software development methods • Experience working with cloud computing environments • Experience developing novel sequencing-based technologies in an interdisciplinary team