Bioinformatics Jobs

POSITION SUMMARY The Simons Foundation is seeking a Bioinformatics/Senior Bioinformatics Engineer (dependant upon experience) to develop and support whole exome and genome sequence data analysis pipelines in both research and operational modalities. This position will report to the Director of Data and Analytics in the informatics group and will work with other engineers and analysts in the... informatics group, as well as with clinical and basic research teams at the foundation. This position will be based in Simons Foundation’s offices in New York City. ESSENTIAL FUNCTIONS/RESPONSIBILITIES • Design, develop and operate computational pipelines for next-generation sequencing data • Work on both large-scale projects and small custom tasks that span a wide variety of analysis problems • Develop new and/or improve upon existing algorithms for variant detection (SNPs and indels) and structural variant detection (CNVs, inversions and translocations) for clinical research purposes • Develop and maintain a knowledge base of variants and annotations discovered in processing of samples MINIMUM QUALIFICATIONS Education • Master’s degree or higher in bioinformatics, computational sciences or related field. Required Attributes • At least 3+ years’ work experience in research-and-development setting in bioinformatics • Experience with next-generation sequencing data • Experience in Linux/Unix cluster environment • Advanced programming skills in Python • Strong background in algorithm development, statistical methods, machine learning and distributed computing. • Extensive knowledge of computational genomics and experience with high-throughput data analysis • Outstanding personal initiative and the ability to work effectively as part of a team • Excellent verbal and written communication skills Desirable Experience • Familiarity with C++, Perl, Matlab and R is desirable. • Familiarity with databases — relational and noSQL — cloud computing and web services is desirable. The Simons Foundation’s Diversity Commitment Many of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds and experiences, and we are committed to cultivating an inclusive work environment. The Simons Foundation actively seeks a diverse applicant pool and encourages candidates of all backgrounds to apply. We provide equal opportunities to all employees and applicants for employment without regard to race, religion, color, age, sex, national origin, sexual orientation, gender identity, genetic disposition, neurodiversity, disability, veteran status, or any other protected category under federal, state and local law

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Title: Senior Bioinformatics Scientist Location: South Plainfield, NJ Admera Health provides genomic and bioinformatic services for researchers working on projects ranging from exploratory to clinical. Operating in a CLIA/CLEP-certified and CAP-accredited environment, all projects are handled with exceptional care. Maximizing efficiency in laboratory services and practices allows Admera to offer substantial competitive pricing to our customers. Our team of experts can help through ongoing consultations for projects requiring fully customizable solutions. Proprietary extraction techniques have been developed that deliver robust results even with difficult low input samples, including blood and FFPE. Responsibilities: • Work collaboratively with bench scientists, comprehend project objectives, and evaluate and provide informatics solutions • Develop and implement bioinformatics analyses, applications, and workflows to expand our genomics and bioinformatics capabilities • Integrate statistical analysis to project design and data interpretations • Maintain and improve back-end of cloud-based genomic interpretation system • Manipulate publicly accessible, commercial, or proprietary genomic, clinical-related databases • Improve user interfaces to bioinformatics software and databases • Work closely with IT specialists to build robust infrastructure • Perform duties in accordance with SOPs and CLIA/CAP regulations • Maintain accurate documentation and records • Implement bioinformatics analysis for high complexity laboratory tests in accordance with SOPs and CLIA/CAP regulations • Enters, updates and maintains databases containing patient specimens • Responsible for clinical test analysis, reporting and maintaining records of patient test results Qualifications: • Ph.D. in Life Science, Bioinformatics, or Computation Biology with 2-3+ years of experience required • High programming proficiency in R, Python, Java, or Perl • Essential knowledge of key biological processes and NGS technology desired • Clinical experience within a CLIA or CAP regulated environment preferred • Concrete bioinformatics skills in analysis of data from various omic platforms • Experience in NGS data analysis • Experience in relational databases (MySQL/PostgreSQL) • Experience in web interface (web frontend) development. Familiarity with bootstrap and python web frameworks like Django/Web2py is a plus • Familiarity/Experience with AWS EC2/ELB/S3 is a big plus • Familiarity in applying statistical approaches to NGS data interpretation • Strong background in software development on Linux system • Strong communication skills, both written and verbal Admera Health employees have a winning attitude and champion innovation, teamwork and accountability through a results-oriented, customer-centric, and fun culture. We offer various health and financial benefits, learning opportunities, competitive compensation, rewarding bonus programs, and a wide range of work/life benefits designed to make your life easier. For more information, please visit www.admerahealth.com. To review and apply to our open positions, please visit www.admerahealth.com/careers. 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About The Knowles Lab The Knowles lab (https://daklab.github.io/) at the New York Genome Center and Columbia University Departments of Computer Science and Systems Biology aims to understand the role of transcriptomic dysregulation across the spectrum from rare to common genetic disease. This involves better characterization of the genetic and environmental factors contributing to RNA expression... and splicing variation. Beyond these specific projects there are opportunities for close collaboration with diverse research groups at NYGC collecting large-scale genomics datasets in the context of neurological disease and developing novel genomic technologies including single cell methods, forward genetic screens and long-read transcriptomics. Position Description The Knowles lab is seeking a Bioinformatics Associate to work on an National Institute of Health (NIH) funded project to maintain and further develop our RNA splicing analysis software tools. This multidisciplinary project is a collaboration with Dr. Towfique Raj’s group in the Departments of Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai. This project will involve applying software engineering best practices to existing tools to make them more efficient, modular and cloud-ready. This position is grant funded for a duration of one-year through an NIH grant, and employment beyond the expiration date of the grant is subject to the availability of additional funding. Key Responsibilities • Refactoring code to be modular, using standard libraries and workflow languages (nextflow or WDL); • Improving statistical model fitting efficiency using GPU-aware machine learning libraries (e.g. tensorflow or Pytorch); • Building standardized Python and conda packages; • Containerization (e.g. Dockerization) of software; • Addressing and debugging github issues. This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time with or without notice. Required Skills Required Experience Position Requirements • BS in computer science, bioinformatics, or a related quantitative field required, MS preferred. • Strong interest in genetics and genomics required. • 1+ years programming experience in Python required (some knowledge of R preferred). • Understanding of Unix systems/command line/bash required. • Experience with cloud-computing preferred. • Some experience with NGS data analysis, functional genomics and/or human genetics preferred. • An understanding of (required) and practical experience (preferred) applying standard software engineering practices (e.g. version control with git, code review, unit testing, standard workflow languages). Competencies • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments. • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so. • Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity. Work Flexibility NYGC has established a flexible work policy to give employees and other staff more ability to balance their work, personal commitments, and commuting challenges. The incumbent in this position is eligible for a flexible work schedule or hybrid remote work arrangement (working onsite on Tuesdays and Thursdays at minimum) with supervisory approval. About The New York Genome Center NYGC is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar). neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity NYGC is committed to creating a workplace where our employees reflect the rich diversity of the New York community— in race, gender, age, cultures and beliefs — and we work to support this diversity through our employment practices. We want our employees to thrive both personally and professionally. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities. FLSA Status - Exempt This position is eligible for relocation assistance. This position is not eligible for visa sponsorship

NYU Grossman School of Medicine is one of the nation's top-ranked medical schools. For 175 years, NYU Grossman School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Health, the Grossman School of Medicine at its core is committed to improving the human... condition through medical education, scientific research, and direct patient care. For more information, go to med.nyu.edu, and interact with us on LinkedIn, Glassdoor, Indeed, Facebook, Twitter and Instagram. Position Summary: We have an exciting opportunity to join our team as a Bioinformatics Analyst. The lab of Prof. Stefan Feske (http://labs.pathology.med.nyu.edu/feske-lab/) at the NYU Grossman School of Medicine and NYU Langone Health is seeking a highly motivated, enthusiastic individual to become part of a team of scientists investigating ion channels in immune cell function. The successful candidate will have the opportunity to interface with a wet-bench scientists and lead analyses on large datasets generated from state-of-the art next-generation sequencing technologies including single-cell approaches. The successful candidate will also be a member of a vibrant group of experienced bioinformaticians in the Applied Bioinformatics Laboratories (http://nyulmc.org/abl). ABL, headed by Prof. Aristotelis Tsirigos, provides computational support and expertise to promote innovative cutting-edge research conducted by principal investigators at NYU Langone Health. This is a great opportunity to acquire high-in-demand bioinformatics skills, develop and publish new analysis tools/pipelines, analyze challenging datasets, and be a co-author on multiple high-impact manuscripts. Job Responsibilities: • Work closely with bench scientists to understand, analyze and help interpret their genomic data • Analyze various types of sequencing data analysis (e.g. RNA-seq, ChIP-seq, ATAC-seq, Hi-C-seq, bisulfite sequencing, whole-genome sequencing) • Mine databases for hypothesis generation or validating information • Perform robust data quality control and validation • Manage data sets on genome browsers • Adapt genomic data analysis pipelines in a rapidly evolving research environment • Develop novel methods for multi-omics data analysis and integration • Other duties as assigned Minimum Qualifications: To qualify you must have a B.S. in Bioinformatics, Systems Biology, Computer Science or related field Knowledge of biology and understanding of key and complex biological concepts (genes, pathways, cancer/immunity and/or stem cells) Ability to work independently while collaborating and assisting the team in its common research goals Attention to detail and ability to work on multiple projects is necessary Excellent communication skills with proficiency in written and oral English Preferred Qualifications: Experience in Unix/Linux systems including HPC environments Scripting languages: Python (preferred) or Perl Statistical packages: R (preferred) or Matlab. 1+ years of experience with sequencing data (two of DNA-seq, RNA-seq and ChIP-seq) 1+ years of experience creating customized sequencing analysis pipelines Qualified candidates must be able to effectively communicate with all levels of the organization. NYU Grossman School of Medicine provides its staff with far more than just a place to work. Rather, we are an institution you can be proud of, an institution where you'll feel good about devoting your time and your talents. NYU Grossman School of Medicine is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sex, sexual orientation, transgender status, gender dysphoria, national origin, age, religion, disability, military and veteran status, marital or parental status, citizenship status, genetic information or any other factor which cannot lawfully be used as a basis for an employment decision. We require applications to be completed online. If you wish to view NYU Grossman School of Medicine's EEO policies, please click here. Please click here to view the Federal "EEO is the law" poster or visit https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm for more information. To view the Pay Transparency Notice, please click here

The New York Stem Cell Foundation (NYSCF) Research Institute is a growing and successful nonprofit whose mission is to accelerate cures through stem cell research. NYSCF is seeking a Staff Scientist, Transcriptomics/Bioinformatics is responsible for building custom pipelines to analyze and interpret biological data generated by teams within the NYSCF Research Institute. You are a skilled... bioinformatician who has knowledge and experience in working with a wide range of human transcriptomic based datasets, including single-cell platforms, bulk RNA-seq, as well as CRISPR screens. You will have demonstrated a solid understanding of biology and genomics, programming skills, and experience with high-throughput molecular sequencing technologies. We offer all full-time employees a comprehensive benefits package that goes into effect on the first of the month following your start date. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and complete the required employment eligibility verification upon hire. The position is located onsite on a full-time basis at our location in Manhattan. NYSCF is an equal opportunity employer, and we value diversity in our company. It ensures equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, veteran status, or any other characteristic protected by law. Our Research Institute facility is a fully COVID-19 vaccinated workplace

The lab of Prof. Stefan Feske (http://labs.pathology.med.nyu.edu/feske-lab/) at the NYU Grossman School of Medicine and NYU Langone Health is seeking a highly motivated, enthusiastic individual to become part of a team of scientists investigating ion channels in immune cell function. The successful candidate will have the opportunity to interface with a wet-bench scientists and lead analyses on... large datasets generated from state-of-the art next-generation sequencing technologies including single-cell approaches. The successful candidate will also work and interact with a vibrant group of bioinformaticians in the Applied Bioinformatics Laboratories (http://nyulmc.org/abl). ABL provides computational support and expertise to promote innovative cutting-edge research conducted by principal investigators at NYU Langone Health. This is a great opportunity to acquire high-in-demand bioinformatics skills, develop and publish new analysis tools/pipelines, analyze challenging datasets, and be a co-author on multiple high-impact manuscripts. Responsibilities · Work closely with bench scientists to analyze and interpret genomic datasets · Analyze various types of sequencing data analysis (e.g. bulk RNA-Seq, single cell RNA-Seq, and less frequently, ChIP-seq, ATAC-seq, whole-genome sequencing) · Mine databases for hypothesis generation or validating information · Perform robust data quality control and validation · Manage data sets on genome browsers. · Adapt genomic data analysis pipelines in a rapidly evolving research environment · Develop novel methods for multi-omics data analysis and integration Required skills · M.Sc. in Bioinformatics, Systems Biology, Computer Science or related field · Knowledge of biology and understanding of key and complex biological concepts (genes, pathways, cancer/immunity and/or stem cells) · Ability to work independently while collaborating and assisting the team in its common research goals · Attention to detail and ability to work on multiple projects is necessary · Experience in Unix/Linux systems including HPC environments · Scripting languages: Python (preferred) or Perl · Statistical packages: R (preferred) or Matlab. · 1+ years of experience with sequencing data (two of DNA-seq, RNA-seq and ChIP-seq) · 1+ years of experience creating customized sequencing analysis pipelines · Excellent communication skills with proficiency in written and oral English We are pleased to offer one of the most competitive compensation packages not only among New York's hospitals and healthcare institutions, but within the corporate sector as well. Add to that a very attractive tuition program, and you'll see just some of the ways that NYU Langone Health demonstrates our commitment to our employees. NYU Langone Health is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. If interested, contact: Stefan.Feske@nyulangone.org with a (i) resume, (ii) brief statement of relevant work experience and interest in this position, (iii) contact information of 2-3 references

Invitae is a healthcare technology company that uses genetic information to empower doctors and patients to make informed medical decisions. Our development team is taming the chaos of biology with cutting-edge methods and high throughput workflows capable of processing thousands of samples each week. We are constantly improving our tools and technologies to deliver the highest quality actionable... information to patients. Behind every sample that comes in through the door we know there is an individual and a family looking for answers. As part of our Bioinformatics Rapid Response team you will help improve our products, workflows and tools in a production setting. You will apply your knowledge of software engineering, computer science and statistics to optimize our assays in various ways such as cost, turnaround time and operational stability. In the team, you will drive execution and own a solution through conception, implementation, validation and production release. You will work and learn among an extraordinary set of peers: bioinformaticians, molecular biologists, and software engineers. Your work will improve the quality of our products and directly impact each of our patients. What you will do: • Evaluate and improve production algorithms and statistical models for NGS and non-NGS assays technologies, to reduce costs, improve turnaround time, increase automation • Critically analyze large production datasets using in-house tools and build custom tools when needed • Write production-level code to implement data-driven improvements • Lead development in a cross-disciplinary setting to define issues, assemble datasets, devise analyses and document conclusions for internal review and regulatory purposes What you will bring: • Advanced graduate degree in bioinformatics, statistics, computer science or a related discipline, or 5+ years of experience working in a bioinformatics role • Deep knowledge and experience analyzing genetics data (including Illumina SBS, PacBio, microarrays, capillary electrophoresis) • Understanding of the statistical and algorithmic foundations of modern variant calling packages such as GATK and techniques for CNV/large events calling • Experience reading and writing source code for large software projects, with strong preference for Python • Excellent written and verbal communication and data presentation skills At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance. #LI-Remote #LI-JM1

The New York Genome Center (NYGC) is looking for a highly motivated individual to join our computational biology group. As a Bioinformatics Scientist, you will be responsible for the analyses and interpretation of cancer genome samples sequenced at NYGC. This includes the maintenance, benchmarking, and continuous improvement of our analysis pipelines, as well as participation in downstream... analyses by applying existing tools and algorithms to analyze cancer sequencing data, collaborating with NYGC staff to develop new tools and with external investigators on the integration of genomics results within their scientific projects. This position will report to the Director of Computational Biology. Job duties will include, but are not limited to: • Contribute to setup, management and maintenance of genomic data analysis pipelines. • Analyze sequencing data using the established pipeline(s) either already in place at NYGC or state-of-the-art workflows developed by others. • Develop and implement innovative computational approaches for the analysis of large sequence datasets from NGS technologies. • Assist, collaborate and consult with external and internal researchers on the analyses and interpretation of cancer NGS data. • Interpret and present the results of the computational and statistical analyses to collaborators and coworkers. • Collaborate with the software engineering team to ensure pipeline upgrades and new pipelines are properly implemented in our production workflow manager. • Mentor Bioinformatics Analysts and Programmers. • Help identify relevant funding opportunities interests and participate in grant writing. • Publish developed methods and scientific findings in scientific journals and give presentations at conferences. • Participate in community outreach. • Stay current on innovations in DNA sequencing technologies and analyses. Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities, and activities may change at any time. Required Experience • PhD. in bioinformatics, computational biology, genetics, computer science or similar required, or master’s degree plus 5 year’s work experience. • Experience in cancer genomics required. • Experience managing and working with next generation sequencing data required. • Extensive knowledge and experience in the use of existing bioinformatics tools and biological databases. • Excellent written and verbal communication skills required. • Experience with cloud computing environments (optional). • Programming skills required; proficiency in python and R required, as well as willingness to learn new programming languages as necessary. • Experience working in Linux and running tasks in a cluster environment (e.g., SGE) required. • Experience working in teams centered around a biological question and with external collaborators required. Competencies • Technical and Professional Skills: Consistently demonstrates skills and knowledge relevant for current role; strives to expand the depth and breadth of technical and professional skills; works with a high level of integrity; exhibits focus and discipline; appropriately prioritizes, manages expectations and delivers on commitments. • Collaborative & Communicative: Models collaboration and teamwork; brings out the best in others; effectively works with all levels, internally and externally; respects and embraces diversity of perspective; communicates clearly and listens carefully; uses good judgment as to what to communicate and when to do so. • Adaptable & Innovative: Adaptable and embraces change; develops new insights and pursues improvements and efficiency; fosters exchange of new ideas and willing to challenge the status quo; takes initiative and is solution-oriented; engages in work with passion and curiosity. About the New York Genome Center The New York Genome Center (NYGC) is an independent, nonprofit, academic research organization dedicated to advancing genomic research. NYGC scientists and staff are furthering new approaches to diagnosing and treating neurological diseases and cancer through their unique capabilities in whole genome sequencing, RNA sequencing, state-of-the art analytics, and the development of genomic tools. NYGC concentrates specifically on disease-based research in the following areas: neuropsychiatric disease (autism, schizophrenia, bipolar); neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, Huntington’s), and cancer. Located in Lower Manhattan, the New York Genome Center was founded by and remains closely affiliated with twelve leading academic medical centers and research universities in the New York region and beyond, engaging in research projects with and for these institutions. Essential to our collaborative work is an outstanding faculty, whose members typically hold a joint appointment at NYGC and a partner university. They support our scientific mission by conducting independent research in areas of mutual interest to us and the wider scientific community. Equal Opportunity Diversity, equity, and inclusion are central to the core mission at the NYGC. We strive to create a workplace environment that is welcoming and fair to all regardless of race, ethnicity, gender, sexual orientation, physical ability, or religion. We believe that when people of various backgrounds, life experiences, and perspectives work together in an inclusive and equitable environment we gain new and valuable perspectives that otherwise would have been missed. Valuing and supporting all NYGC employees as individuals while helping them realize their full potential is critical to promoting greater collaboration, innovation, and discovery – fostering a sense of belonging for our greatest strength, our people. We recognize that there is still work to be done that will require sustained commitment from the entire organization. The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, creed, color, gender, religion, national origin, sexual orientation, age, disability, genetic predisposition or carrier status, protected veteran or military status, domestic violence victim status, partnership status, caregiver status, alienage or citizenship status, marital status, or any other characteristic protected by applicable law. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities. FLSA Status – Exempt This position is eligible for visa sponsorship and relocation assistance

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and... volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Prevail Therapeutics is a wholly owned subsidiary of Eli Lilly and Company and is based in New York City. We are leaders in developing gene therapies for Parkinson’s disease, dementias and other genetically defined neurodegenerative diseases. Organization Overview: We are seeking a Research Engineer (Bioinformatics) to help design and engineer our next generation of gene therapy products. You will use provide broad bioinformatics and analytical support for our Research and Manufacturing teams. You will work on innovative computational genomics projects that address challenges in gene therapy, genome editing and neurodegeneration. We seek an entrepreneurial and self-motivated individual who can function with a high degree of independence and work collaboratively within a multidisciplinary team that is dedicated to the development of new therapies for neurodegenerative diseases. Responsibilities: The successful candidate will work across all Prevail functional teams to: • Implement NGS sequencing data analyses to support R&D and AAV manufacturing. • Perform comparative DNA sequence analyses and implement computational tools for designing siRNAs, CRISPR gRNAs and CDS optimization. • Support statistical analyses, maintain databases/portals for Prevail studies and develop R/Shiny tools for interactive visualization • Leverage and integrate large public databases to support pipelines and programs Basic Requirements: • BS in scientific discipline with 2+ years of experience in bioinformatics or MS in Bioinformatics/related field Additional Preferences: • Proficiency in at least one major scripting language (Python, Perl or similar). • Strong understanding of human genetics, and NGS data analysis is required. • Excellent organizational skills and attention to detail; strong interpersonal, planning, and communication skills. Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response. Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at workplace_adjustment@lilly.com

Job Code and Payroll Title 009401 BIOINFORMATICS PROGR 3 Job Summary... The Bioinformatics Programmer position involves establishing pipelines using existing computer algorithms for the analysis of RNA, DNA and TCR sequencing as well as Cytof data. The position will also involve developing new algorithms and pipelines as needed, commencing with but not limited to single cell RNA and TCR sequencing of immune cells from immunotherapy-treated and untreated cancer patients. The candidate will be expected to make independent and innovative contributions to a variety of experimental analyses that may lead to contributions to scientific publications. Eventually, the candidate will implement end-user needs for everyone in the laboratory to be able to use the algorithms in the pipeline for large scale studies. Organization Campus Req Number 62932BR Job Title Bioinformatics Programmer Employee Class Career Percentage 100% Shift Length 8 Hours Shift Days Additional Shift Details Monday - Friday, 40 hours per week Bargaining Unit 99 - Policy-Covered (No Bargaining Unit) Job Category Clinical Systems / IT Professionals Required Qualifications • Bachelor's degree in biological science, computational / programming, or related area • Minimum 3+ years of related experience and/or training. • Thorough knowledge of bioinformatics methods, applications programming, web development and data structures. • Thorough knowledge of bioinformatics programming design, modification and implementation. • Thorough skills associated with statistical analysis and systems programming • Experienced with Unix • Knowledge of relevant biology • Ability to produce high-quality reports and documentation Preferred Qualifications • Master's degree in biological science, computational/programming • Advanced degree in Information Technology or related discipline • Understanding of relational databases, web interfaces, and operating systems. • Strong project management skills. • Thorough knowledge of modern biology and applicable field of research. • Communication skills to work with both technical and non-technical personnel in multiple fields of expertise and at various levels in the organization. • Ability to communicate technical information in a clear and concise manner. • Ability to interface with management on a regular basis. • Self-motivated, work independently or as part of a team, able to learn quickly, meet deadlines and demonstrate problem solving skills. • Thorough knowledge of web, application and data security concepts and methods. • Experienced with open-source development (e.g., maintenance, contributions) • Experienced with compute clusters and job schedulers • Experienced with version control (e.g., Git) and corresponding repositories (e.g., GitHub) • Experience with cloud computing • Skills to communicate complex information in a clear and concise manner both verbally and in writing. • Skilled in Tableau or other data visualization tools, SQL tables, queries and stored procedures, Python or other programming language(s), Familiarity with ETL processes, VBA in MS Excel or MS Access, charting/visualizations using MS Excel. • Demonstrated ability to communicate technical information to technical and non-technical personnel at various levels in the organization • Demonstrated ability to work with others from diverse backgrounds. Demonstrated effective communication and interpersonal skills. Demonstrated service orientation skills • Demonstrated strong problem-solving skills. Able to learn effectively and meet deadlines • Critical thinking skills and attention to detail Position Type Full Time Department Name Helen Diller Family Comprehensive Cancer Center Equal Employment Opportunity The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information. Department Description The UCSF Cancer Immunotherapy Program (CIP) at the UCSF Helen Diller Family Comprehensive Cancer Center (HDFCCC) comprising of the Cancer Immunotherapy Clinic and the Cancer Immunotherapy Lab on the Parnassus Campus, brings together expert UCSF physicians from across all cancer sub-specialties, to work closely with scientists from UCSF and beyond to develop the cancer treatments of the future. About UCSF The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world’s leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells. Pride Values UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence – also known as our PRIDE values. In addition to our PRIDE values, UCSF is committed to equity – both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at diversity.ucsf.edu Join us to find a rewarding career contributing to improving healthcare worldwide. Location Mission Bay (SF