Bioinformatics Jobs

About Us: The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe. Exciting Opportunity at MSK: Our Pathology and Laboratory Medicine Department is looking for a Bioinformatics Software Engineer to join a dynamic team supporting state‑of‑the‑art molecular diagnostics and cancer genomics programs. You will play a key role in developing software tools, web applications, and data workflows that empower our clinicians and researchers to interpret complex genomic information and advance precision oncology. Role Overview • Build web applications and APIs that enable genomic data visualization and clinical reporting • Collaborate closely with bioinformaticians, laboratory scientists, researchers, and clinicians to translate workflow needs into robust software solutions • Develop, optimize, and maintain computational workflows for NGS data processing • Improve performance, scalability, and reliability of existing pipelines and tools • Ensure data quality, reproducibility, and proper documentation across all projects Key Qualifications • BS in Bioinformatics, Computer Science, or related field + 5 years of experience OR MS in Bioinformatics, Computer Science, or related field + 2 years of experience • Strong programming skills in Python • Experience in web development (e.g., Flask, Django, React) • Experience with relational databases (PostgreSQL, MySQL) and/or NoSQL (MongoDB) • Hands-on experience with containerization (Docker, Kubernetes) • Familiarity with version control (Git/GitHub) and CI/CD workflows • Understanding of NGS data analysis workflows • Strong debugging, analytical, and problem-solving skills Preferred: • Experience with cloud computing (AWS, GCP, or Azure) • Knowledge of cancer genomics, variant calling, and annotation Core Skills • Ability to translate scientific and clinical needs into maintainable, well‑designed software • Strong communication skills and comfort collaborating with multidisciplinary teams • Ability to work in fast‑paced research and clinical environments • Commitment to reproducible, traceable, and well‑documented work Additional Information • Schedule: hybrid, at least 2 days a week in office, must reside in the NYC metro area • Location: Joy Building, 321 E 61st Street, NYC • Reporting to: Manager, Bioinformatics Pathology and Laboratory Medicine Helpful Links: • Compensation Philosophy • Benefits Pay Range: $121,400.00 - $200,400.00 FSLA Status: Exempt Closing: At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

Bring more to life. Are you ready to accelerate your potential and make a real difference within life sciences, diagnostics and biotechnology? At Integrated DNA Technologies (IDT), one of Danaher’s (https://danaher.com/our-businesses) 15+ operating companies, our work saves lives—and we’re all united by a shared commitment to innovate for tangible impact. You’ll thrive in a culture of belonging where you and your unique viewpoint matter. And by harnessing Danaher’s system of continuous improvement, you help turn ideas into impact – innovating at the speed of life. Our team at Integrated DNA Technologies (IDT), is united by a commitment to collaboration and scientific excellence, building on a strong foundation of innovation, expertise, and reliability. Guided by our vision to help researchers rapidly move from the lab to life-changing advances, we work closely with global partners to accelerate progress and genomics breakthroughs across fields like cancer, infectious disease, rare genetic disorders, and more. At IDT, you’ll be part of a culture rooted in continuous learning and improvement—where your growth fuels our mission to accelerate the pace of genomics and helps shape a healthier, brighter future for all. Learn about the Danaher Business System (https://www.danaher.com/how-we-work/danaher-business-system) which makes everything possible. The Bioinformatics Scientist – Field Applications is responsible for the bioinformatics support for IDT’s secondary analysis software Archer Analysis which is utilized by Next Generation Sequencing product lines FusionPlex, VariantPlex, LiquidPlex and Immunoverse. The focus of this position is to enable our customer’s success and satisfaction by providing dedicated onsite and remote assistance on the data analysis related inquiries. This position’s main territory will be North America, with primary responsibility within the United States. This position reports to the Manager, Bioinformatics Science – Field Applications AMR/APAC and is part of the Global Scientific Applications Support Organization working remotely to cover Western United States. In this role, you will have the opportunity to: • Coordinate and conduct software trainings and data reviews using Archer Analysis and associated data at customer sites and/or remotely. • Provide remote/onsite customer educations on software pipelines and features. • Investigate and resolve customer inquiries and troubleshooting cases via email and calls. • Discuss and resolve challenging cases collaboratively with other members of the Customer Success team. • Engage in pre-sales conversations when technical expertise is required. The essential requirements of the job include: • Postgraduate degree in Genomics or Bioinformatics (or a related discipline). An equivalent combination of training and experience (minimum 3-5 years) will also be considered  • Hands on involvement analyzing NGS data through academic or professional experience • Previous experience in field applications/customer support or another customer facing role with demonstrated internal and external relationship-management skills in the genomics industry Travel, Motor Vehicle Record & Physical/Environment Requirements: • Ability to travel at least 50% within defined territory and occasionally supporting other territories as needed • Must have a valid driver’s license with an acceptable driving record • Ability to lift, move or carry equipment up to 20lb, any other physical requirements It would be a plus if you also possess previous experience in: • Ideal candidate will have extensive experience with NGS clinical oncology solutions applications and/or experience within the Life Sciences industry • Experience working with CRM systems, Salesforce preferred IDT, a Danaher operating company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it’s a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at Danaher Benefits Info (https://leplb1040.upoint.alight.com/ah-angular-afirst-web/#/web/danaher/cp/preauth-home) . At IDT we believe in designing a better, more sustainable workforce. We recognize the benefits of flexible, remote working arrangements for eligible roles and are committed to providing enriching careers, no matter the work arrangement. This position is eligible for a remote work arrangement in which you can work remotely from your home. Additional information about this remote work arrangement will be provided by your interview team. Explore the flexibility and challenge that working for IDT can provide. The annual salary range for this role is $105,000-$120,000. This is the range that we in good faith believe is the range of possible compensation for this role at the time of this posting. This range may be modified in the future. This job is also eligible for bonus/incentive pay. We offer comprehensive package of benefits including paid time off, medical/dental/vision insurance and 401(k) to eligible employees. Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole discretion unless and until paid and may be modified at the Company’s sole discretion, consistent with the law. #LI-JP1 #Remote Join our winning team today. Together, we’ll accelerate the real-life impact of tomorrow’s science and technology. We partner with customers across the globe to help them solve their most complex challenges, architecting solutions that bring the power of science to life. For more information, visit www.danaher.com . Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. The U.S. EEO posters are available here (http://www.eeoc.gov/sites/default/files/2023-06/22-088_EEOC_KnowYourRights6.12ScreenRdr.pdf) . We comply with federal and state disability laws and make reasonable accommodations for applicants and employees with disabilities. If reasonable accommodation is needed to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please contact:1-202-419-7762 or applyassistance@danaher.com .

About the position We are seeking a highly motivated Bioinformatics Analyst to join the research group of Dr. Robert Burk at Albert Einstein College of Medicine. Our group conducts molecular epidemiology and microbiome research with an emphasis on the human microbiome (cervicovaginal, oral, and gut) and HPV-related neoplasia. This role is central to translating large-scale sequencing datasets into rigorous, publication-ready results with direct relevance to chronic disease, cancer prevention and infectious disease research. Our work has been published in high-impact journals such as Nature Communications and Cell. The ideal candidate is an independent problem solver who is comfortable taking ownership of analysis workstreams, building and maintaining reproducible pipelines, and driving projects forward from raw data to interpretable outputs. They should be collaborative, communicate clearly with wet lab and epidemiology teams, and proactively propose analytic approaches that strengthen the science and accelerate progress. Responsibilities • Pipeline development and leadership: Design, implement, document, and maintain end-to-end NGS pipelines for microbiome and HPV genomics applications (e.g., 16S/ITS1 amplicon sequencing, shotgun metagenomics, viral/HPV sequencing, bisulfite sequencing, and viral integration analyses). • Large-scale data processing: Perform robust QC, read processing, reference alignment, taxonomic and functional profiling, strain-level analyses where appropriate, and reproducible reporting for cohort-scale datasets. • Clinical and epidemiologic integration: Harmonize sequencing outputs with clinical and epidemiologic metadata (including complex longitudinal designs), perform data cleaning and validation, and generate analysis-ready tables. • Statistical and computational analysis: Conduct and interpret statistical analyses using R and/or Python, including microbiome-specific methods (alpha/beta diversity, ordination, PERMANOVA, differential abundance) and epidemiologic modeling (regression and related approaches), with publication-quality visualizations. • Project leadership and communication: Lead defined analysis workstreams, set realistic milestones, communicate risks and dependencies early, and present progress and results in lab meetings and to collaborators. • Troubleshooting and optimization: Diagnose and resolve complex issues (pipeline failures, batch effects, contamination artifacts, inconsistent metadata, compute bottlenecks). Improve robustness, scalability, and runtime efficiency on shared compute environments. • Reproducibility and best practices: Use version control (Git), structured documentation, and reproducible execution practices (workflow managers and/or containerization when appropriate). Maintain clear provenance from raw data to results. • Scientific contribution: Propose fresh analytic ideas, evaluate new tools and methods, and contribute to interpretation and narrative framing of findings. • Manuscripts and grants: Contribute figures, methods text, and analyses for manuscripts and grant applications. Requirements • Bachelor’s degree in bioinformatics, computational biology, biostatistics, epidemiology, computer science, or a related field; Master’s or PhD preferred. • Strong programming ability in R and/or Python, plus comfort working in a Unix/Linux environment (shell scripting, HPC-style workflows). • Demonstrated experience processing and analyzing NGS data, including building or extending pipelines rather than only running existing ones. • Solid understanding of basic statistical concepts and the ability to translate scientific questions into appropriate analyses. • Track record of independent problem solving, attention to detail, and producing reliable, well-documented outputs. • Strong communication skills and a collaborative mindset for working with interdisciplinary teams. • Practical Experience: The candidate is expected to have practical experience with bioinformatics work (handling NGS reads off the machine, etc.) and be willing and eager to adapt to new approaches. Nice-to-haves • Experience in microbiome bioinformatics (16S, ITS1, shotgun metagenomics) and/or viral genomics with familiarity with phylogenetics, or integration-related analyses. • Experience working with protected clinical or epidemiologic data and with best practices for data security and governance. • Experience analyzing large cohorts and handling confounding, batch effects, and complex study designs (longitudinal, nested case-control, matched studies). • Comfort translating analyses into clear figures, methods, and results text suitable for high-impact manuscripts

Bioinformatics Scientist We are seeking a talented and highly motivated Bioinformatics Scientist to support the development of Roche Diagnostics Molecular Assays that have a global impact on patient care. This role requires a broad understanding of assay development across diverse technologies, including NGS, Nanopore sequencing, and PCR. The successful candidate will collaborate closely with bioinformaticians, wet lab scientists, and external customers to design, implement, and maintain internal algorithms and tools for clinical diagnostic assay development. The Opportunity: Collaborate with multidisciplinary teams of molecular and computational biologists, as well as wet lab scientists, to design, optimize, and troubleshoot advanced high-throughput sequencing assays and workflows for clinical diagnostic applications. Contribute bioinformatics expertise throughout the assay development lifecycle, including initial sequencing, validation, and production implementation, by developing and maintaining analytical tools and pipelines for processing diagnostic data from tumor, germline, and cell-free DNA samples. Create, implement, and streamline bioinformatics tools and workflows in partnership with wet lab scientists to enhance assay development efficiency and data quality. Provide hands-on troubleshooting to ensure data quality, integrity, and accessibility across the diagnostic workflow, while addressing the needs of internal and external stakeholders through scientific and business analyses. Advocate for best practices in documenting, training, and scaling algorithms, tools, and workflows to ensure reproducibility and scalability. Clearly communicate project outcomes and team progress across various teams and organizational functions to promote alignment and collaboration. Who You Are: You have a PhD or Master's degree in Bioinformatics, Computational Biology, Statistics, or a related field. You have 6+ years of industry experience in clinical diagnostics or a related domain. You have expertise in DNA/RNA sequencing data analysis and interpretation. You are proficient in programming skills in R and/or Python, with experience working in a distributed Linux environment. You are proficient in creating clear, insightful visualizations of complex biological data, with strong presentation skills to effectively communicate results to both technical and non-technical audiences. You have a strong understanding of molecular biology principles and hands-on familiarity with next-generation sequencing laboratory processes. Able to work closely with bench scientists to troubleshoot experimental and workflow issues. You are skilled in writing and maintaining bioinformatics workflows using workflow management systems such as Snakemake or Nextflow. You have demonstrated the ability to independently develop informatics solutions and contribute to scientific informatics initiatives. You have a solid understanding of cancer biology and in vitro diagnostics (IVD). Preferred Qualifications: Proficiency in C++ or Java is a plus. Relocation benefits are not available for this posting. The expected salary range for this position based on the primary location of California is $139,400-$258,800. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants. Tagged as: Life Sciences

(ID: 2026-1586) Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH). Benefits We Offer: • 100% Medical, Dental & Vision Coverage for Employees • Paid Time Off and Paid Holidays • 401K match up to 5% • Educational Benefits for Career Growth • Employee Referral Bonus • Flexible Spending Accounts: • Healthcare (FSA) • Parking Reimbursement Account (PRK) • Dependent Care Assistant Program (DCAP) • Transportation Reimbursement Account (TRN) Axle is seeking a skilled Bioinformatics Engineer to join our team supporting major pharmaceutical clients. In this role, you will review, assess, optimize, integrate, and extend production-grade bioinformatics workflows for high-throughput sequencing analysis. The ideal candidate combines deep expertise in genomics analysis methods with strong software engineering practices and cloud computing experience. Key Responsibilities • Evaluate existing bioinformatics pipelines for performance, accuracy, and maintainability, identifying opportunities for optimization and enhancement • Develop, extend, and maintain Nextflow workflows for bulk RNA-seq, single-cell RNA-seq, DNA variant calling, methylation analysis, and emerging assay types • Architect scalable solutions capable of processing thousands of samples efficiently on Google Cloud Platform • Optimize data input/output operations across pipeline modules to minimize bottlenecks and reduce computational costs • Prepare and structure analysis outputs for visualization platforms and downstream statistical or machine learning applications • Implement best practices for workflow versioning, containerization, testing, and documentation • Collaborate with computational biologists, data scientists, and software engineers to integrate pipelines into broader analytical ecosystems • Stay current with advances in sequencing technologies and analytical methods, evaluating and incorporating new tools as appropriate Required Qualifications • Master's degree in bioinformatics, computational biology, computer science, or a related field (or equivalent experience) • 3+ years of hands-on experience developing and maintaining bioinformatics pipelines in a production environment • Proficiency with Nextflow (DSL2) and familiarity with workflow management concepts • Strong experience with RNA-seq analysis (both bulk and single-cell) and DNA sequencing workflows (variant calling, methylation) • Working knowledge of Google Cloud Platform services (Compute Engine, Cloud Storage, Batch, Life Sciences API, or similar) • Proficiency in Python and/or R for scripting, data manipulation, and tool development • Experience with containerization technologies (Docker, Singularity) • Familiarity with version control systems (Git) and CI/CD practices • Strong understanding of genomic file formats (FASTQ, BAM, VCF, BED) and common bioinformatics tools (STAR, Salmon, BWA, GATK, Bismark, Cell Ranger, Seurat, Scanpy) Preferred Qualifications • PhD in a relevant field • Experience with nf-core pipelines and community standards • Familiarity with workflow orchestration at scale (Cromwell, AWS Batch, or similar platforms) • Experience optimizing cloud costs and resource utilization for large-scale genomics workloads • Knowledge of data visualization tools and frameworks (e.g., R Shiny, Plotly, custom dashboards) • Experience in pharmaceutical, biotech, or regulated research environments • Familiarity with FAIR data principles and metadata standards What We Offer • Opportunity to work on cutting-edge genomics projects with industry-leading pharmaceutical partners • Collaborative environment with experts in bioinformatics, data science, and software engineering • Professional development and growth opportunities • Competitive salary and benefits package Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed. The diversity of Axle's employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital sta

Organization Overview The Laboratory of Chemical Immunology and Proteomics applies synthetic chemistry, chemical biology, and proteomics methods toward the goals of discovering and characterizing (a) novel selective chemical probes that perturb the functions of key proteins regulating immunological and neuroimmunological processes; (b) new mechanisms for small molecule-induced protein degradation; and, more broadly, (c) the pharmacological landscape and signal transduction pathways in immune and neuroimmunological disorders. By developing and applying innovative chemical proteomic profiling technologies, we aim to enrich our understanding of the molecular differences between pathologic and physiologic states in immune cells and cells of the nervous system and to leverage them from a pharmacological perspective for the development of new therapies that not only target specific immune cell subtypes, but also the defined activation states of these cells. Please see www.vinogradovalab.com for more information. Overview We seek a highly motivated Bioinformatics Assistant to join the Laboratory of Chemical Immunology and Proteomics. Responsibilities Responsibilities include: • Facilitating proteomics and genomics workflows for data processing and analysis • The development and application of data analysis and visualization tools Qualifications REQUIRED QUALIFICATIONS: • Bachelor’s degree in Computational Biology, Computer Science, Bioinformatics, Biostatistics, Mathematics, or related field • At least one year of work experience in large scale biological data analysis (Proteomics and NGS - preferred) PREFERRED QUALIFICATIONS: • Proficiency in Python, and other relevant computer languages, with working knowledge of statistical methods and data analysis methods • Must be able to work independently as well as part of a team in a fast-paced, highly collaborative environment • Strong organizational, record-keeping, and interpersonal skills • Excellent critical thinking, and analytical skills The Rockefeller University is an equal opportunity employer – veterans/individuals with disabilities. Qualified applicants will receive consideration for employment without regard to characteristics protected by applicable local, state or federal law, including but not limited to disability and protected veteran status. The salary of the finalist selected for this role will be set based on various factors, including but not limited to organizational budgets, qualifications, experience, education, licenses, specialty, and training. The hiring range provided represents The Rockefeller University's good faith and reasonable estimate of the range of possible compensation at the time of posting. Compensation Range: Min USD $50,000.00/Yr. Compensation Range: Max USD $55,000.00/Yr.

About the position Join a mission-driven team transforming cancer care through technology! We are a passionate group of software engineers, bioinformaticians, and clinical collaborators developing next-generation informatics solutions that directly impact patient outcomes. Our work spans petabyte-scale biological datasets, high-performance computing, and cutting-edge AI/ML tools to support clinical decision-making. We are seeking a Bioinformatic Software Engineer who thrives in fast-paced environments, is eager to learn, and is excited to build secure, scalable systems that help visualize and report genomic results guiding treatment and clinical trial enrollment. Responsibilities • Work and collaborate with a top-notch team of software engineers, bioinformatics researchers, AI/ML teams, data scientists, system engineers, and physicians to support clinical-grade informatics infrastructure. • Create and maintain technical documentation including user guides, operational run books, and standard operating procedures. • Develop DevOps framework and implement standards, processes, and controls for release and deployment activities. • Develop API services, data dashboards, visualizations, and cutting-edge web portals. • Design and build AI/ML solutions - including large language models (LLMs), retrieval-augmented generation (RAG), deep learning, and classical ML - integrated into secure, scalable full-stack clinical applications. Requirements • Bachelor’s degree in computer science, or related discipline with 4 years of hands-on software engineering experience, preferably developing scientific software such as bioinformatics or biomedical informatics systems, Master's with 2+ yrs. preferred. • 3+ years of firsthand experience with programming languages like Python, Java, or JavaScript frameworks such as ReactJS • Experience working with relational (MySQL, Postgres, etc.), and no-SQL (MongoDB) database technologies. • Experience building high-throughput and scalable RESTful APIs using Python frameworks (such as Flask, FastAPI, etc.) • Experience working with high-performance computing platforms either on-premises (LSF, Slurm, etc.) or on the cloud (especially AWS) • Experience with agile software development practices, and experience using tools such as JIRA, or Rally • Experience with deep learning frameworks (PyTorch, TensorFlow) – and libraries such as scikit-learn, numpy and transformers for model training and inference. • End-to-end production AI/ML experience (LLMs, RAG), including prompt engineering, fine-tuning, vector search, model evaluation and monitoring, and MLOps within regulated clinical or PHI environments. • Strong team collaboration and communication skills. • Passion for learning new technologies and methodologies. • Customer-centric mindset with a desire to understand clinical workflows. • Resilience and creativity in problem-solving. • Ability to thrive in a dynamic, fast-paced environment.

Job Title: Bioinformatics Software Engineer – NGS Sequencing Systems Location: South San Franisco, CA 94080 (2-3 days onsite) Duration: 04/14/2026 to 12/18/2026 Interview Process: 1. phone (15-20mins) 2. In-person (1 hr) SKILLS • Bachelor’s or Master’s degree in Computer Science, Bioinformatics, Computational Biology, Software Engineering, or related field w/ MIN 3 years exp • Experience working in NGS sequencing or genomics environments • Experience working with data processing pipelines or scientific data systems • Strong experience with Oracle databases. • Proficiency in SQL and PL/SQL • Strong programming skills in Python. • Experience with Bash scripting. • Experience developing or supporting workflow pipelines using WDL • Experience with Java and Java EE web application development • Experience supporting LIMS systems or laboratory data platforms

Department: Informatics & Information Technology Location: New York, NY Salary: 124,000.00 - 204,700.00 USD Annual Job details About Us: The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursue our mission at MSK and around the globe. Exciting Opportunity at MSK: Join a mission-driven team transforming cancer care through technology! We are a passionate group of software engineers, bioinformaticians, and clinical collaborators developing next-generation informatics solutions that directly impact patient outcomes. Our work spans petabyte-scale biological datasets, high-performance computing, and cutting-edge AI/ML tools to support clinical decision-making. We are seeking a Bioinformatic Software Engineer who thrives in fast-paced environments, is eager to learn, and is excited to build secure, scalable systems that help visualize and report genomic results guiding treatment and clinical trial enrollment. Role Overview: • Work and collaborate with a top-notch team of software engineers, bioinformatics researchers, AI/ML teams, data scientists, system engineers, and physicians to support clinical-grade informatics infrastructure. • Create and maintain technical documentation including user guides, operational run books, and standard operating procedures. • Develop DevOps framework and implement standards, processes, and controls for release and deployment activities. • Develop API services, data dashboards, visualizations, and cutting-edge web portals. • Design and build AI/ML solutions - including large language models (LLMs), retrieval-augmented generation (RAG), deep learning, and classical ML - integrated into secure, scalable full-stack clinical applications. Key Qualifications: • Bachelor’s degree in computer science, or related discipline with 4 years of hands-on software engineering experience, preferably developing scientific software such as bioinformatics or biomedical informatics systems, Master's with 2+ yrs. preferred. • 3+ years of firsthand experience with programming languages like Python, Java, or JavaScript frameworks such as ReactJS • Experience working with relational (MySQL, Postgres, etc.), and no-SQL (MongoDB) database technologies. • Experience building high-throughput and scalable RESTful APIs using Python frameworks (such as Flask, FastAPI, etc.) • Experience working with high-performance computing platforms either on-premises (LSF, Slurm, etc.) or on the cloud (especially AWS) • Experience with agile software development practices, and experience using tools such as JIRA, or Rally • Experience with deep learning frameworks (PyTorch, TensorFlow) – and libraries such as scikit-learn, numpy and transformers for model training and inference. • End-to-end production AI/ML experience (LLMs, RAG), including prompt engineering, fine-tuning, vector search, model evaluation and monitoring, and MLOps within regulated clinical or PHI environments. Core Skills: • Strong team collaboration and communication skills. • Passion for learning new technologies and methodologies. • Customer-centric mindset with a desire to understand clinical workflows. • Resilience and creativity in problem-solving. • Ability to thrive in a dynamic, fast-paced environment. Additional Information: • Schedule: Monday - Friday, 37.5 hours, hybrid (in office quarterly, therefore, must reside in NYC Metro Area • Location: 1275 York Ave, NYC • Reporting to: Bioinformatics Software Engineer V Helpful Links: • Compensation Philosophy • Benefits #LI-HYBRID Pay Range: $121,400.00 - $200,400.00 FSLA Status: Exempt Closing: At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. Application Process • 01 Step 1: Complete an Online Application • 02 Step 2: Interview Process • 03 Step 3: Provide References • 04 Step 4: Extension of Job Offer • 05 Step 5: Onboarding • 06 Step 6: New Employee Orientation

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position Sequencing Bioinformatics Specialist The Opportunity: As a Sequencing Bioinformatics Specialist, you will play a pivotal role in supporting the Sequencing & Life Sciences franchise at Roche. This position focuses on bioinformatics as it relates to the Sequencing instruments and associated products within the Roche Sequencing portfolio. You will contribute to the growth and success of accounts ranging from Commercial Sequencing Providers to Academic Medical Centers, Large Reference Labs, Molecular Pathology Labs, Biotech, Pharma, and Universities. These institutions leverage genomic methods, including next-generation sequencing (NGS), in both research and clinical applications. Key Responsibilities: Sales Engagement & Expertise: • Drive achievement of sales quotas by actively engaging in sales activities. • Provide technical expertise throughout the sales process. • Offer effective consultations on applications, assay design, data analysis, and interpretation. Strategic Sales Planning & Implementation: • Develop and execute strategic sales plans to meet revenue targets and grow market share. Technical Presentations & Consultations: • Deliver product presentations, demonstrations, and in-depth consultative discussions. • Key technical areas include: • Sample preparation for sequencing. • NGS data analysis, management, sharing, and storage. • Analysis, annotation, interpretation, and reporting of NGS testing for clinical and research settings. • Integration of Laboratory Information Management Systems (LIMS) across workflows. • Cloud-based pipeline optimization and automation. • Bioinformatics approaches tailored to specific genomic applications. Cross-Functional & Team Collaboration: Align with Sequencing Sales Specialists, Genomic Solutions Specialists, and Regional Business Managers to implement strategic territory plans. • Train local sales teams and support colleagues to enhance sales of sequencing platforms and informatics solutions. • Work closely with marketing, product management, and service/support teams to align sales efforts with organizational goals and customer needs. Customer Engagement & Representation: • Serve as a trusted advisor to customers, offering guidance to overcome informatics challenges and achieve their scientific goals. • Represent Roche at conferences, trade shows, and networking events to enhance brand awareness and thought leadership. Market Insight & Adaptation: • Stay ahead of industry trends, market dynamics, and competitive landscapes to refine sales strategies and seize new business opportunities. This is a National field-based role. Candidate can be based anywhere in the U.S. Relocation assistance is not provided for this role. Travel Requirements: • Estimate travel 25-50% of the time. Who You Are: You are a driven individual who thrives on making an impact and charting your professional growth. You seek opportunities to work across functions and geographies, preferring a role that serves as a launchpad for development rather than a static title. • You hold a Bachelor's Degree degree in Bioinformatics, Molecular Biology, Genetics, or Biochemistry or equivalent experience. • You hold 5 years relevant sales experience, Bioinformatics experience or equivalent experience. Technical Expertise: • Deep knowledge of next-generation sequencing (NGS) technologies, platforms, methodologies, and applications. • Proficiency in sequencing data analysis and interpretation, including primary, secondary, and tertiary analysis workflows. • Expertise in clinical informatics, bioinformatics, or adjacent fields. • Familiarity with sequencing applications (current and emerging), data formats, file types, data footprints, and analysis methods. • Solid understanding of life sciences markets, coupled with the ability to identify customer needs and articulate value propositions. • Exceptional communication, presentation, and interpersonal skills, with an ability to convey complex scientific concepts to varied audiences. • Self-motivated, proactive, and results-oriented, with a proven track record of exceeding sales targets. • Ability to manage multiple priorities in a dynamic, fast-changing environment. Preferred Qualifications: • Master's or Ph.D. • Previous roles in direct sales or customer-facing positions are advantageous. ​The expected salary range for this position based on the primary location of Indiana is $132,800 - $246,600. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position is eligible to earn incentive compensation that is calculated and paid in accordance with the applicable Incentive Compensation Plan for the role. This position also qualifies for the benefits detailed at the link provided below. Benefits #LI-JW2 Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Indianapolis. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.