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More Bioinformatics Jobs

Research Assistant Member - biostatistics/bioinformatics

Oklahoma City, OK
2022/06/11.

Research Assistant Member – biostatistics/bioinformatics OverviewOMRF is an independent, not-for-profit biomedical research institute adjacent to the University of Oklahoma Health Sciences Center (OUHSC) campus in Oklahoma City. Oklahoma City offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy. OMRF’s excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic. ResponsibilitiesThe Arthritis and Clinical Immunology Research Program is hiring a Research Assistant Member with biostatistics or... bioinformatics training who is ready to start a transitional faculty position in data analytics. This mentored position would progressively develop novel research design and analytic approaches to optimize rigor and outcomes of clinical research, clinical trials and/or trans-omic analyses of complex human autoimmune disease data. Performs a wide variety of analyses, including but not limited to parametric and non-parametric statistics. Evaluates the statistical methods and procedures used to obtain data and to ensure validity, applicability, efficiency, accuracy, reliability and usability of data. Develops statistical analysis plans and eports results of statistical analyses, including information in the form of graphs, charts, and tables. Conveys results for presentations to non-statistical audiences. Analyzes and interprets statistical data and prepares conclusions. Assists with data visualization. Identifies relationships and trends in data, as well as any factors that could affect the results of research. Writes and publishes peer-reviewed manuscripts, presents findings at national/international meetings, and is mentored to write successful grant applications.This is a transitional position for scientists who have completed an exemplary postdoctoral experience or exceptional new graduates who show promise to develop independent projects and attract extramural grant support. Incumbents are characterized by considerable experience, highly distinctive competence, and a demonstrated ability to perform independently. Benchmark Accountabilities: Conducts advanced scientific research with a high degree of independence and innovation that provides significant contributions to the lab and respective program Manages research projects including budget oversight, as well as providing research mentoring for students, trainees, and colleagues while receiving faculty level mentoring appropriate for emerging principal investigators Personally communicates findings orally and prepares at least the first draft of publications and applications Prepares and submits proposals for individual and/or research program project grant support Engages in laboratory wide teamwork and seeks new opportunities for exploration and collaboration Knowledge, Skills and AbilitiesSound knowledge of the principles and practices of scientific theory, research and investigative methods; to possess innate curiosity about data analytics as applied to biologic problems; demonstrates skill in formulating and testing hypotheses; ability to personally design and conduct data analyses; to analyze and summarize data and results; communicates effectively both orally and in writing in order to competently prepare scientific papers and grant proposals; mentors students, trainees, less experienced scientists and other team members in a manner that will guide/direct their work, yet also inspires, encourages and helps develop them with progressive competency with leadership skills QualificationsPh.D. in Biostatistics, Statistics, Bioinformatics, Applied Mathematics, Epidemiology or other relevant area, and/or M.D., or equivalent and typically two years of exemplary postdoctoral experience. Must have the ability to perform data analyses using appropriate coding languages (such as R) or statistical software programs. Must be a team-player with good organizational and communication skills. Must be able to work independently, as well as highly attentive to detail, and dependable. OMRF has mandated the COVID-19 vaccine for all employees, excluding those with an approved medical or religious accommodation, as a condition of employment. Applicants must have received, or be willing to receive, a COVID-19 vaccine by their start date to be considered for employment.To apply, visit https://careers-omrf.icims.com/jobs/1389/research-assistant-member/job?in_iframe=1OMRF’s excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic.jeid-ed09aa3aaaa3f547988980894f19ba8d

Bioinformatics Scientist Fellowship

Silver Spring, MD
2022/06/11.

Description A research opportunity is available with the High-Performance Integrated Virtual Environment (HIVE) Team within the Office of Biostatistics and Epidemiology (OBE), Center for Biologics Evaluation and Research (CBER), at the Food and Drug Administration (FDA) in Silver Spring, MD... The HIVE Team is seeking a bioinformatics and data analyst for fellowships in Masters and/or Ph.D. training programs. The participant will train under a team of multi-disciplinary scientists and perform bioinformatics data analysis in the rapidly changing environment of next-generation sequencing and other omics technologies. As a result of this training the participant will acquire new skills in NGS quality assessment analysis, genome and transcriptome analysis and improve their software development and communication skills. Under the guidance of a mentor, responsibilities will include: • Assisting researchers' access, analyze, store and transmit NGS data and information, and collaborating effectively • Identify, import and evaluate genomic datasets and pipelines • Develop novel bioinformatic pipelines, scientific algorithms and adopt existing tools • Communication of results and interpretation to a diverse audience, including senior FDA scientists, collaborators, and internal stakeholders This program, administered by ORAU through its contract with the U.S. Department of Energy to manage the Oak Ridge Institute for Science and Education, was established through an interagency agreement between DOE and FDA. The initial appointment is for one year, but may be renewed upon recommendation of FDA contingent on the availability of funds. The participant will receive a monthly stipend commensurate with educational level and experience. Proof of health insurance is required for participation in this program. The appointment is Full time at FDA in the Silver Spring, Maryland, area. Participants do not become employees of FDA, DOE or the program administrator, and there are no employment-related benefits. Completion of a successful background investigation by the Office of Personnel Management is required for an applicant to be on-boarded at FDA. OPM can complete a background investigation only for individuals, including non-US Citizens, who have resided in the US for a total of three of the past five years. FDA requires ORISE participants to read and sign their FDA Education and Training Agreement within 30 days of his/her start date, setting forth the conditions and expectations for his/her educational appointment at the agency. This agreement covers such topics as the following: • Non-employee nature of the ORISE appointment; • Prohibition on ORISE Fellows performing inherently governmental functions; • Obligation of ORISE Fellows to convey all necessary rights to the FDA regarding intellectual property conceived or first reduced to practice during their fellowship; • The fact that research materials and laboratory notebooks are the property of the FDA; • ORISE fellow's obligation to protect and not to further disclose or use non-public information. Qualifications The qualified candidate should have received a masters or doctoral degree in one of the relevant fields (eg Bioinformatics, Computational Biology). Degree must have been received within the past five years. Preferred Skills: • Scientific background in Bioinformatics, Molecular Biology, Computational Biology or a related field • Experience in either R or Python (or other Scripting languages such as BASH) • Familiarity with diverse NGS analysis tools (eg samtools, bedtools, GATK, BWA, Bowtie, IGV), secondary analysis tools (eg muTect VarScan, VarDict) and statistical or machine learning algorithms (DeSEQ2, clustering, t-SNE) • Familiarity with publicly available data sources (eg TCGA, ENCODE, COSMIC) and annotations methods • Excellent collaborative, verbal and written communication skills

Bioinformatics Scientist

Anywhere
2022/06/11.

The Bioinformatics Scientist will take lab-generated data and create computational models that allow further manipulation and experimentation, perform incremental analysis required to process large amounts of data generated in a high-throughput Next Generation Sequencing (NGS) laboratory devoted to analysis of genomics data with a focus on long- and short-read sequencing technologies, including... bulk and single-cell analysis. The NGS data analysis will require both strong programming skills and quantitative/statistical analysis. The successful candidate will thrive in a dynamic, fast-paced working environment and contribute directly to our company culture and success. Candidates must have a graduate degree In Bioinformatics, Computational Biology, or related discipline with a minimum of five (5) years' experience in NGS (Illumina) data analysis. Excellent programming skills, including Python and R, along with demonstrated experience with SQL databases, Unix and REST API; additional preference will be given to candidates knowledgeable in HPC, non-SQL databases, cloud computing, long reads and single-cell NGS. Excellent verbal and written communication skills are required. You must be able to work in a team environment that values open and honest communication, embraces challenge, innovation and continuous improvement, works hard and loves to have fun, is fast-paced and displays a can-do attitude. If this is you and you can prove it, you could be a great fit for our team

Senior/Staff Bioinformatics Scientist - Remote

New York, NY
2022/06/11.

At Cepheid, we are passionate about improving health care through fast, accurate diagnostic testing. Our mission drives us, every moment of every day, as we develop scalable, groundbreaking solutions to solve the world's most complex health challenges. Our associates are involved in every stage of molecular diagnostics, from ideation to development and delivery of testing advancements that... improve patient outcomes across a range of settings. As a member of our team, you can make an immediate, measurable impact on a global scale, within an environment that fosters career growth and development. Cepheid is proud to work alongside a community of six fellow Danaher Diagnostics companies. Together, we're working at the pace of change on diagnostic tools that address the world's biggest health challenges, driven by knowing that behind every test there is a patient waiting. Learn about the Danaher Business System which makes everything possible. The Staff Bioinformatics Scientist will help drive bioinformatics projects related to the design of highly multiplexed molecular diagnostics through all stages of planning, design, computational verification and empirical validation in collaboration with experimental scientists and other team members. Primary responsibilities include identification of unique nucleic acid sequences and signatures in various organisms and creation of novel, automated methods for design of primers and probes in complex assays. This role involves extensive collaboration with Bioinformatics Engineers, Bioinformaticians, Molecular Biologists, and others at all stages of assay development from planning to commercialization. This position can be based Remotely or relocation assistance will be provided if you'd like to relocate to Sunnyvale, CA. In this role, you will have the opportunity to: • Rapidly prototype novel, innovative algorithms for the design of multiplexed PCR primers and probes compatible with Cepheid's instrumentation and experimental methods in response to both long-term and emerging company needs. • Assist Bioinformatics Engineers in the development of a robust computational pipeline for automated and semi-automated assay design. • Assist in the development of rigorous methodologies for analyzing PCR primer performance data, perform analyses, and communicate results to experimental scientists and others in the company. • Think creatively in a collaborative environment about novel, innovative solutions for difficult assay design problems. • Analyze data and debug results in order to identify avenues for future development and improvement. The essential requirements of the job include: • Master's degree in bioinformatics or a related field with 3+ years of related work experience OR a Doctoral degree with 1+ years of related work experience. • Proficient and hands-on in Python in a Linux environment, preferably including experience implementing and maintaining bioinformatics pipelines. • Proactive self-starter with strong analytical and troubleshooting skills. Able to conduct and plan independent projects with minimal supervision. • Fundamental understanding of PCR, or ability to learn. It would be a plus if you also possess previous experience in: • PCR primer and probe design. • Design and/or analysis of molecular diagnostics assays. Cepheid, a Danaher company, offers a broad array of comprehensive, competitive benefit programs that add value to our lives. Whether it's a health care program or paid time off, our programs contribute to life beyond the job. Check out our benefits at danaherbenefitsinfo.com. When you join us, you'll also be joining Danaher's global organization, where 80,000 people wake up every day determined to help our customers win. As an associate, you'll try new things, work hard, and advance your skills with guidance from dedicated leaders, all with the support of powerful Danaher Business System tools and the stability of a tested organization. Danaher Corporation and all Danaher Companies are committed to equal opportunity regardless of race, color, national origin, religion, sex, age, marital status, disability, veteran status, sexual orientation, gender identity, or other characteristics protected by law. We value diversity and the existence of similarities and differences, both visible and not, found in our workforce, workplace and throughout the markets we serve. Our associates, customers and shareholders contribute unique and different perspectives as a result of these diverse attributes. The EEO posters are available here. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us at applyassistance@danaher.com to request accommodation. If you've ever wondered what's within you, there's no better time to find out

Senior Director, Bioinformatics

Richmond, CA
2022/06/11.

Manager: VP of Genome Engineering Department: Genome Engineering Location: Richmond, California, with options for remote (US West Coast preferred... Sangamo Therapeutics is a genomic medicine company building value with cutting-edge work across four distinct but complementary technology platforms - gene therapy, cell therapy, in vivo genome editing, and in vivo genome regulation. Using its deep scientific expertise and proprietary zinc finger genome engineering technology, Sangamo is working to create genomic cures for patients suffering from severe genetic diseases for which today's medicines can only treat symptoms. At Sangamo, we are passionate about transforming lives by building a robust, sustainable, differentiated, innovative, and high value genomic medicine pipeline that addresses patients with life-limiting conditions. Sangamo takes pride in being the first to edit endogenous human genes, first to treat patients with gene edited T cells, and first to treat patients with in vivo genome editing. Our top priority is to meet the needs of patients with commitment and compassion. Along with our commitment to science and to our patients, we also endeavor to create an inclusive environment that promotes and values diversity. Sangamo is a company where individuals can flourish, grow and develop their expertise. We are seeking top talent to join our mission. Let's build a better future together. JOB SUMMARY: Sangamo Therapeutics is seeking an experienced and innovative Senior Director to lead our Bioinformatics team. The successful candidate will lead a group of 6+ bioinformatics experts to support pre-clinical and clinical teams in the application of genome engineering technologies for the treatment of human diseases. We are looking for a bold problem solver who can help us achieve significant leaps in capabilities for both computational biology and required IT infrastructure. The position requires adaptability, creativity, and a capacity for constant innovation in pursuit of company goals. The environment is exciting and fast-paced and offers the opportunity to work and publish at the cutting edge of genome engineering research. ESSENTIAL FUNCTIONS: • Supervision of a core bioinformatics team (6+ and growing) that exists within a corporate research environment. • Collaboration with IT partners and NGS Core staff to support company-wide bioinformatics needs. • Support and lead bioinformatics staff who design, build, and operate data pipelines to perform scientific analyses. • Maintaining a group culture that implements best practices for code annotation and review. • Working with IT partners to support R&D staff with evolving needs for data storage and security. EDUCATION, EXPERIENCE AND SKILLS REQUIREMENTS: • Ph.D. in bioinformatics, computational biology, or affiliated field, preferably with 10+ years of industrial experience. • Strong track record of mentoring bioinformatics / scientific staff and proactively supporting their career development. • Proficiency in Python and familiarity with R required. • Knowledge of established and emerging technologies for next generation DNA sequencing (Illumina, PacBio, etc.) • Experience deploying cloud computing and establishing / negotiating cost structures with providers that are sustainable for organizational needs. • Knowledge and experience with best practices for traceability and reproducibility of computational analyses. • Hands on lab experience with molecular biology a plus. • An ability to work in a team-oriented, multidisciplinary environment. OTHER QUALIFICATIONS: • Experience with molecular design for genome engineering (zinc fingers, TALs, CRISPR, miRNA, shRNA,etc.) • Experience applying machine learning to biological datasets. Sangamo is an equal opportunity employer Sangamo is committed to fostering belonging for all employees and embraces diversity, equity, and inclusion in recruiting and hiring. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual's race, color, sex, gender identity, gender expression, religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws Commitment to Safety Sangamo requires all U.S. workers to be fully vaccinated against COVID-19 as of their start date. This requirement is a condition of employment at Sangamo, and it applies regardless of location or classification of role. If you are unable to receive the vaccine & booster, you will have an opportunity to request a reasonable accommodation consistent with applicable laws. Note to External Recruiters: We do not accept unsolicited resumes from any source other than from the candidates themselves

Bioinformatics Systems Engineer

Menlo Park, CA
2022/06/11.

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science... to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit www.grail.com. Detect cancer, when it can be cured at GRAIL! One of the foremost challenges facing Grail is getting our technology into the hands of clinicians and patients to assist in decision making over the spectrum of cancer detection and treatment stages. To meet this need, GRAIL is seeking a Bioinformatics Systems Engineer to supervise the development of regulated diagnostic products and project manage efforts to transition research into product-ready software. You will be an embedded member of the teams that plan product development activities, perform early research, produce bioinformatics pipelines, and support operations activities for on-market products. This work will require a high level vision of the target product needs as well as in depth understanding of the research objectives and approaches. You will need a clear understanding of software and machine learning development practices. Although location in the San Francisco Bay Area is helpful, this position can be remote. GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation

Director, Computational Medical & Bioinformatics

Sioux Falls, SD
2022/06/11.

*Create Your Career With Us!*.Sanford Health is one of the largest and fastest-growing not-for-profit health systems in the United States. We're proud to offer many development and advancement opportunities to our nearly 50,000 members of the Sanford Family who are dedicated to the work of health and healing across our broad footprint... • Facility:* Imagenetics Building. Location:* Sioux Falls, SD. Address:* 1321 W 22nd St, Sioux Falls, SD 57105, USA. Shift:* Day.Job Schedule:* Full time.Weekly Hours:* 40.00.Department Details* Flexibility with remote work; if working remote full time, travel to Sioux Falls will be required Job Summary* Manage and apply resources to general bioinformatics and medical informatics operations, guided by experience, organizational goals and operational strategies. Also responsible for the management of cyclical projects. Work on complex computational bioinformatics matters where analysis of issues, data and process require advanced specialist knowledge and in-depth industry and technical knowledge. Contribute to the development of genomic clinical assays and their required validation (ie polygenic risk scores) Oversee the computational bioinformatics and medical informatics team within the Imagenetics program across the enterprise. Collaborate with medical genetics lab leadership, the technology solutions team and many others. Train, supervise and mentor members of the bioinformatics and medical informatics team. Oversee bioinformatics pipelines for genetic data including planning, quality control, and project specific analyses. Address the technical performance of the various experiments, especially for the array data, by comparing raw, quantile, cubic spline and rank invariant for each experiments. For RNA Sequence data, assist with splice variant analysis and single nucleotide polymorphisms (SNP)/copy number variation (CNV) analysis. Familiarity with security and privacy requirements applicable for working with patient data in a medical environment and in the development of appropriate ethically and legally compliant policies.Qualifications* Bachelor's degree in bioinformatics, computer science or related field. Advanced degree in bioinformatics, medical informatics or related field preferred. Minimum five years of related experience in bioinformatics, medical informatics or a closely related field required. Two years in a managerial or leadership position and a demonstrated record of mentoring preferred. Experience in the analysis of high-throughput DNA and RNA sequencing data, including alignment, quality measurements, variant calling, variant annotation, variant prioritization, incidental findings reporting, and transcript quantification is required. Computational experience is to include demonstrated database management, process management, next generation sequence analysis, and presentation of data to clinicians. Preference will be given to individuals with expertise in database vitalization, genetic/epigenetic analyses and medical and/or research informatics experience Benefits* Sanford Health offers an attractive benefits package for qualifying Full time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, sick leave and paid time off. To review your benefit eligibility, visit https://sanfordcareers.com/benefits . Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1-877-673-0854 or send an email to (see below) . Sanford Health has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment Req Number:* R-0090677.Job Function:* Research.Featured:* No

Scientist I, Bioinformatics

Brisbane, CA
2022/06/11.

OPPORTUNITY Mammoth is seeking a Scientist I with expertise in bioinformatics to join its Diagnostics team. This role will focus on designing new diagnostic assays using our DETECTR™ technology ... The successful candidate will contribute towards Mammoth’s efforts to develop innovative diagnostic products that enable consumers to access their health information in a timely manner. The Scientist I, Bioinformatics will work closely with both the research and development teams on a variety of projects including primer and gRNA design. COMPANY Mammoth Biosciences is harnessing the diversity of life to power the next generation of CRISPR products. Through the discovery and engineering of novel CRISPR systems, the company is enabling the full potential of its platform to read and write the code of life. Mammoth aims to develop permanent genetic cures through best-in-class in vivo and ex vivo therapies and to democratize disease detection with on-demand diagnostics. Mammoth can provide enhanced diagnostics and genome editing for life science research, healthcare, agriculture, biodefense and more. Based in the San Francisco Bay Area, Mammoth Biosciences is co-founded by CRISPR pioneer and Nobel Laureate Jennifer Doudna and Trevor Martin, Janice Chen, and Lucas Harrington. The firm is backed by top institutional investors including Redmile Group, Foresite Capital, Senator Investment Group, Sixth Street, Decheng, Mayfield, NFX, and 8VC, along with leading individual investors including Brook Byers, Tim Cook, and Jeff Huber. TEAM The Diagnostics team is advancing our CRISPR-based DETECTR® platform to address unmet needs across the continuum of testing. From laboratories to the home, our mission is to democratize diagnostics with CRISPR. It is our policy and intent to provide equal opportunity to all persons without regard to race, color, religion, political affiliation, sex/gender (including gender expression/identity, pregnancy, childbirth and related medical conditions), marital status, registered domestic partner status, sexual orientation, age, ancestry, national origin, veteran status, disability, medical condition, genetic characteristics, and/or any other basis protected by law. This policy covers all facets of employment including, but not limited to: recruitment, selection, placement, promotions, transfers, demotions, terminations, training, and compensation

Bioinformatics Engineer

Frederick, MD
2022/06/11.

The Military & Veteran's Health Operation of Leidos is currently looking for a Bioinformatics Engineer to support biological research at the Biological Defense Research Directorate (BDRD) at the Naval Medical Research Center (NMRC) in Frederick, MD. The BDRD within NMRC facilitates biological defense research including not only rapid detection of infectious diseases of global importance and the... enhancement of global disease surveillance for early pathogen detection and response, but also new approaches in medical countermeasures, such as advancing phage therapy to treat multidrug resistant bacterial infections. The Bioinformatics Engineer plays an important role in the quality control, assembly, annotation, and dissemination of microbial (bacterial and viral) genomes, metagenomes, transcriptomes and metatranscriptomes in a military medical research setting. The Bioinformatics Engineer collaborates with a team of bioinformatics analysts, computational biologists, and infectious disease experts to manipulate and query high-throughput genetic data to answer complex biological questions in a fast-paced environment. This involves installation and testing of open source bioinformatic software as well as working with a team to create new pipelines, workflows, and standards for customized solutions. Primary Responsibilities The ideal candidate shall: Manipulate and process raw sequencing data from in-house Next Generation Sequencing (NGS) platforms (MiSeq, NextSeq500, NovaSeq6000, PacBio, MinION), microarrays, publicly accessible databases, and/or external collaborators. Assist in microbial genome assemblies and downstream analyses to a complete (polished genome) standard, they will also contribute to other tasks such as analysis of RNAseq data and bioinformatic pipeline development and testing. Perform quality control of sequencing data, genome assembly, gene annotation, etc. Perform well in a fast-paced, fluid environment. Integrate high-throughput data from multiple sequencing platforms. Use a variety of bioinformatic tools and potentially develop new software applications to solve salient problems in the field of genomics. Download, install, and benchmark open-source software packages from a variety of sources (GitHub, SourceForge, etc.). Assist staff scientists in summarizing research data, preparing posters, and/or presenting results via conference presentations, scientific publications, or project reports. Attend internal meetings and teleconferences as well as external meetings with collaborators and stakeholders when deemed appropriate. Contribute to technical reports, presentations and manuscripts for publication. Assist with appropriate training of other personnel. Work is to be performed on a government installation. The normal work week is Monday - Friday 0900 to 1730; regular telework one or more days a week may be possible after an initial acclimation period, dependent on the mission space and supervisor approval. Candidates may need to work evenings and weekends on very rare occasions. 10% travel, including OCONUS, may be required. Basic Qualifications The candidate will be required to acquire, at a minimum, a SECRET classification access level. Preference will be given to a candidate who already has this clearance level. Due to Federal contract requirements, US citizenship is required. Strong background in genomics, bioinformatics computer science, bacterial or viral genetics, and/or computational biology. Candidates must have completed a Master's degree from an accredited US university, or international university of equivalent standard, in Bioinformatics, Computer Science (combined with experience or education in biology or bioinformatics), Computational Biology, Mathematics or a closely related area. Candidates must have at least 2-4 years of hands-on experience in Bioinformatics. Possess programming skills in languages such as JAVA, PERL, PYTHON, and statistical software such as R or R Studio. Maintain a familiarity with next generation sequencing and current standards in bioinformatics. Have excellent verbal and writing communications skills. Be able to think independently and must have excellent problem-solving skills. Be able to perform under deadlines and in austere environments. Must be able to sit extensive hours and lift 25 lbs. without assistance. Experience in phage genetics and/or pathogen discovery is a plus. Preferred Qualifications Experience in a military medical research laboratory is a plus. Ability to work well independently with little to no supervision. Naval Health East - NHE Pay Range: Pay Range $60,450.00 - $93,000.00 - $125,550.00

Bioinformatics Scientist I - D3b

Philadelphia, PA
2022/06/11.

Location: LOC_ROBERTS-Roberts Ctr Pediatric Research Req ID: 162076... Shift: Days Employment Status: Regular - Full Time About Us We’re seeking breakthrough makers! Children’s Hospital of Philadelphia was built on the belief that we can change lives. Today, in every role throughout our hospital, research institute and care network, the 22,000 members of our workforce are finding new ways – big and small – to make a difference for the patients and families we serve. If you are ready to challenge yourself, be inspired and grow – no matter what your role – you just may be the kind of breakthrough maker who will thrive at CHOP. Job Summary The Bioinformatics Scientist I position is an entry level position for a non-PhD level professional. The focus of the position is development, maintenance, and evolution of the tools that support management and analysis of genomic, proteomic, and other complex molecular data types. This includes the support of internal bioinformatics software, implementation and modifications of existing algorithms, and execution of routine tasks of limited complexity within the general area of bioinformatics analysis. The position allows for a wide variety of activities described within the job responsibilities and encompasses positions within both research and clinical environments. All activities occur with a moderate to high degree of supervision and the individual will rely on a high degree of peer-to-peer mentorship. The Bioinformatics Scientist I is primarily focused on the support of higher level bioinformatics personnel but may have minor direct interaction with collaborators and designees to resolve primarily technical issues and solutions. Job Responsibilities Pre-Analysis (35%): Contributes to the maintenance and development of bioinformatics tool portfolio by developing knowledge of internally developed systems, open-source programs, and commercial applications. Provides efficient data management support. • Works with bioinformatics group members to develop functioning pipelines upstream of customized analysis workflows. • Maintains pipelines by staying current with evolving algorithms and standards and incorporating into pipeline. • Executes robust development testing for commonly used applications such as data processing pipelines. • Optimizes performance of applications by working with scientific computing and information systems groups to optimize hardware/software parameters. • Defines and prioritizes requirements for pipeline development over time to incorporate new technologies and platforms via functional communication with bioinformatics group members and bioinformatics end users. • Identifies appropriate open-source and commercial products that serve needs of pipeline and/or customized analyses of end users. • Implements and maintains commercial and open-source software for common bioinformatics and genomics data analysis. • Implements, updates and maintains locally stored data resources required for various analysis tasks. • Provides ad hoc support and one-on-one and group-based training on key bioinformatics software, features, and workflows. • Provides efficient data management support including file transfers, data formatting and manipulation, and basic integration of data from a variety of experimental and reference resources. • Develops and maintains working relationship with data providers such as sequencing cores within CHOP and infrastructure groups such as information systems. • Continually keeps abreast of evolving data generation platform fundamentals, file-specific information representation, and strategic application of code base to optimize value of data. • Maintains working knowledge of available commercial and openly accessible knowledge bases as they apply to bioinformatics analysis. Job Responsibilities (Continued) Coding (35%): Codes and generally supports both ad hoc, single task applications and larger pipeline applications that may combine multiple 3rd party and internally developed applications for genomics/proteomics/other complex data types and projects. • Implements, maintains, and regularly contributes to formal and bioinformatics group-centralized code management system. • Adopts appropriate forking and other strategies for robust code development. Apply to general bioinformatics group code base. • Adopts best practices for code development consistent with larger bioinformatics group. This includes choice of language based on the type of solution being developed, the likely life cycle and downstream usage of the resulting application, and integration with other systems. • Ensures that all routinely used tools (e.g. those included in shared analysis pipelines) are versioned and managed through a source control system. • Ensures that configuration files that provide parameters to algorithms and analysis software are versioned and managed through a source control system. • Develops and implements automated data-driven testing processes that test reproducibility of results between versions of pipeline software. • Develops and implements automated deployment processes that build and configure systems from source control repositories, eliminating the need to manually modify configuration files. • Regularly documents code, troubleshoot, and provide training when necessary. Data Analysis (10%): Analyzes data of high complexity by applying sound statistical and commonly accepted bioinformatics methods to -omics data under supervision from mentors and peers. • Develops robust analysis plans under supervision. • Incorporates QA/QC in analysis workflows. • Delivers analytical endpoints such as feature identification, annotation, characterization, prioritization, etc. • Reports results using, primarily, spreadsheets and, secondarily, abstracted materials such as slides and visuals. Collaboration (10%): Works with both bioinformatics group members and end users/clients to understand specific needs in bioinformatics and end user-specific domains. • Attends group and team meetings and contributes primarily factual information regarding processes and approach. • Defers to mentors and peers in establishing relationships, but works within boundaries to accomplish analytical goals. Academic Output (10%): Contributes to presentations, grants, and manuscripts under supervision by mentors and peers. Required Education and Experience Required Education: Bachelor’s Degree in biological or computational discipline. Preferred Education, Experience & Cert/Lic Preferred Education: Master’s Degree in biological or computational discipline. Preferred Experience: More than 3 years in applied bioinformatics, computational, and genomics/proteomics areas. Additional Technical Requirements • Strong UNIX/LINUX expertise required. • Experience with Python, Perl, Scala, Ruby or other programming languages required. • Experience with Apache Spark strongly preferred. • Experience working under Zeppelin, Jupyter or other notebook environments strongly preferred. • Experience with R strongly preferred. • Experience with genomic data analysis strong preferred. • Experience with pipeline or workflow development frameworks preferred. • Experience with data management preferred. • Familiarity with open source and commercial bioinformatics resources and software preferred. • Experience or knowledge of technologies commonly used in biological labs, such as PCR, cloning, electrophoresis gels, and cell culture preferred. • Knowledge of the working mechanism of microarray, NGS, mass spectrometry, or other high-throughput technologies and awareness of their strengths and weaknesses, as well as applicability to a specific biological problem is preferred. • Familiarity with resources of genomic data sets and analysis tools, such as UCSC Genome Browser, Bioconductor, ENCODE, and NCBI databases is preferred. • Accountability and attention to timelines. • Excellent organization and communication skills with an emphasis on strong presentation skills. • Ability to work in a team environment. • Eager to learn new things and contribute to scientific discoveries. To carry out its mission, it is of critical importance for the Children’s Hospital of Philadelphia (CHOP) to keep our patients, families and workforce safe and healthy and to support the health of our global community. In keeping with this, CHOP has mandated all workforce members on site at any CHOP location for any portion of their time be vaccinated for COVID-19. This mandate also applies to workforce members performing work for CHOP at non-CHOP locations. The CHOP COVID-19 vaccine mandate is in alignment with applicable local, state and federal mandates. CHOP also requires all workforce members who work in patient care buildings or who provide patient care to receive an annual influenza vaccine. Employees may request exemption consideration for CHOP vaccine requirements for valid religious and medical reasons. Please note start dates may be delayed until candidates are fully immunized or valid exemption requests are reviewed. In addition, candidates other than those in positions with regularly scheduled hours in New Jersey, must attest to not using tobacco products. EEO / VEVRAA Federal Contractor

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