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More Bioinformatics Jobs

Bioinformatic Scientist

Hazelwood, MO
2024/04/13.

Description Come and join a family-owned global company with a long-term vision, and a human-centered culture.We are searching for a bioinformatics scientist to join the Sequencing team in the R&D Microbiology department. This opportunity offers the chance to work in a fast-paced environment with a dedicated and collaborative team. The Bioinformatics Scientist is responsible for designing... improving, modifying, and operating data analysis pipelines. Provide bioinformatics support to R&D. Description Responsibilities Develops and implements tools and reference databases for genomic analysis of eukaryotic pathogens Analyzenext-generationsequencing (NGS)datasuch asWGS and targeted sequencingand othermicrobiome data Construct NGS libraries for the assigned pipeline, which may be whole genomeor amplicon andoperation of related sequencing platform Generate high-quality reports forsequencing requestsdocumentation, communicate with team members effectively, and good time management. Interface with data scientists from across the company to leverage and develop new state of the art machine learning tools, data analysis capabilities, and informatic systems. Trainingotherstaff on the use of relevant bioinformatics software and tools. Collaborative attitude for department and inter-departmental activities both within the US and internationally Qualifications/ Requirements Bachelors Degree in Bioinformatics, Computer Science, Statistics, orarelated field with at least 5 yearsofwork experience in sequencing data analysis. Masters Degree in Bioinformatics, Computer Science, Statistics, orarelated field with at least 2 yearsofwork experience in sequencing data analysis. Knowledge of prokaryotic and eukaryotic molecular biology and microbiology. Solid computational skills and a deep understanding of NGS data and its analysisarerequired. Experience with bioinformatics tools (Blast,Resfinder, CLC workbench, Galaxy)arerequired. Codingskillsin at least one language (Perl, Python, R, etc.). Proficiency in Unix/Linux environment, including proficiency inshell scripting. Contribute tojournal publications and presentationsat professional meetings. Critical and Analytical thinking Skill to manage multiple projects simultaneously. Excellent communication and interpersonal skills

Senior Bioinformatics Scientist

Boston, MA
2024/04/13.

Research Computing at Boston Children’s supports basic, translational, and clinical research by providing researchers with access to digital tools and technologies. Our computing environment consists of high-performance computing clusters, virtual machines, PetaByte-scale high-performance storage and cloud platforms. We work with BCH scientists to develop solutions in support of cutting-edge... research ranging from genomics to epigenetics and transcriptomics, proteomics and metabolomics. The Senior Bioinformatics Data Scientist will work with PhD-level bioinformatics scientists and researchers who have single-cell RNA-seq, single-cell ATAC-seq, spatial transcriptomics, bulk RNA-seq and ChIP-seq data to investigate mouse and human diseases as well as with other pediatric scientists at BCH. The primary responsibilities will be building pipelines for the analysis, integration and sharing of these data. You will analyze, integrate different types of next-generation sequencing data and interpret the results and will have the opportunity to publish high-profile papers with prominent authorship depending on the intellectual contribution. The ideal candidate should have enthusiasm for developing collaborative relationships and a desire to foster the use of bioinformatics data in research studies. Responsibilities include: • Providing computational support services to Boston Children's Hospital scientists and clinicians by applying a wide range of bioinformatics tools, methods and technologies. • With minimal supervision and direction, completing highly complex assignments in the required timeframe; consistently adhering to and Promoting standard operating procedures and best practices; maintaining and upgrading a wide range of Research Computing tools, methods, and technologies, migrating data, documenting changes, and adjusting internal processes; resolving highly complex problems associated with assignments and seeking supervisor assistance when needed. • Routinely leading, co-leading, or participating in complex bioinformatics projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectives; • Training staff and researchers; effectively tailoring presentations; developing, implementing and maintaining knowledge management systems. To qualify you must have: • Minimum of 4-year Bachelor's degree in STEM. A minimum of one year of position-specific experience, which might potentially include experience acquired through MSc or Ph.D. studies. Preference for candidates with a Ph.D. in Bioinformatics, Computational Biology or related. • Extensive knowledge of the use of bioinformatics computations in high-performance computing environments, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation, etc. • Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters. • Ability to resolve a wide range of complex Research Computing assignments in support of biomedical research. Ability to routinely lead complex projects and coordinate project teams; readiness to seek advice and guidance when needed and to operate effectively in collaboration with scientists and clinicians; ability to follow, improve and create technical documentation and standard operating procedures. • Strong publication record. Ability to effectively convey messages through written communication that are tailored to target audience; meeting discussions and one-on-one verbal communications are clear and effective; ability to conduct effective meetings, to present in departmental and hospital forums, and to develop training instructions and manuals

Principal/Lead Bioinformatics Research Scientist

Memphis, TN
2024/04/13.

The Principal/Lead Bioinformatics Research Scientist functions independently to coordinate large-scale bioinformatics projects, providing project oversight, scientific and technical advice, programming support, and other input as required to achieve established objectives. Coordinates the specialized expertise of bioinformatics colleagues to achieve scientific objectives. Establishes best... practice recommendations, creates educational materials, and participates in educational initiatives at the laboratory, departmental, and/or institutional level. The new Department of Host-Microbe Interactions is seeking a talented and highly motivated Principal Bioinformatics Research Scientist or Lead Bioinformatics Research Scientist with extensive experience in large-scale microbial genomic data analysis to create and direct the new Microbial Computational Genomics and Bioinformatics Laboratory at St. Jude Children’s Research Hospital. The Microbial Computational Genomics and Bioinformatics Laboratory's mission is to support initiatives on microbial genomic, phylogenomic, and computational needs of researchers in the Department of Host-Microbe Interactions and the Center for Infectious Disease Research. The laboratory is a major initiative backed by substantial support as a part of our institutional strategic plan and will be fully integrated with research in microbial evolution, microbial pathogenesis, virology, the microbiome, computational biology, and data sciences at St. Jude Children’s Research Hospital. The focus of this position is on bacterial and viral genomics, using specimens and data obtained from our healthcare system to address key questions such as the acquisition of antimicrobial resistance, genome heterogeneity, outbreaks, transmission, and the identification of potential targets for the generation of novel therapies. This will be achieved using a combination of approaches, including: short-and long-read whole genome sequencing; phylogenomic, transcriptomic, and bioinformatics approaches involving electronic health data; and experimental data generated by collaborating partners. Data analysis will focus on answering clinical questions, generating insights to prevent infections, and building predictive models of disease susceptibility. The successful candidate will assemble a team of Ph.D.- and MS-level bioinformaticians and data scientists to analyze and interpret newly generated as well as existing large collections of microbial whole-genome sequences and metagenomes, using cutting-edge bioinformatics approaches to address project aims. The director will present research findings at project meetings, scientific conferences, and outreach/training events. There will be opportunities to initiate new projects and collaborate with other groups at St. Jude, including clinicians, basic scientists, and data scientists. The ideal candidate should have: • A PhD and extensive postdoctoral experience in microbial genomics, phylogenomics, bioinformatics, computational biology, and data science. • A strong CV that includes high-profile publications in the field of computational biology and microbial genomics. • Extensive expertise in analyzing, interpreting, and visualizing microbial genomics and microbiome datasets generated by high throughput sequencing technologies including short- (Illumina) and long-read- (e.g. PacBio and Oxford Nanopore) whole genome sequencing. • Extensive experience performing statistical analyses of large microbial genomic datasets and validation of genomic pipelines. • Expert-level proficiency in relevant programming languages such as R and Python, preferably in a High-Performance Computing (HPC) environment. • Preferably, proficiency in tools for ensuring reproducibility of pipelines, such as workflow management systems (e.g., nextflow or snakemake), and version control (e.g., git). • Preferably, experience with database management systems such as MySQL. • Extensive expertise in data integration and harmonization. • Possess a deep understanding of essential bioinformatics concepts and algorithms, e.g., alignment, SNP nucleotide calling, classification of nucleotide and protein sequence, phylogenetics, and genomic assembly. • Previous experience working in the field of infectious diseases is preferred. • Proven problem-solving skills and collaborative nature in fast-paced environment. • Excellent communication and presentation skills. Responsibilities: • Develop and apply state-of-the-art computational approaches to characterize and assemble microbial genomes and metagenomes. • Attract, recruit, and supervise staff to create a strong team for the operation of the Microbial Computational Genomics and Bioinformatics Laboratory. • Collaborate with the St. Jude Children’s Research Hospital data science initiative to develop computational pipelines for handling large, complex genomic datasets requiring custom approaches to accommodate project-specific analytical requirements. • Interface and collaborate with the IT department to develop and maintain capabilities for analysis, interpretation, and storage of the genomic data. • Maintain a high level of professional expertise through familiarity with scientific literature and scientific networking. • Create and implement educational and outreach programs to enhance microbial genomics capabilities and usage within the St. Jude Children’s Research Hospital community. • Train MS and PhD level graduate students in microbial computational genomics. • Collaborate and enable external funding applications. Minimum Education: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Principal Bioinformatic Research Scientist Minimum Experience: • Minimum Requirement: Bachelor's degree with 13+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 11+ years of relevant post-degree experience (OR) PhD with 8+ years of relevant post-degree experience. • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Lead Bioinformatic Research Scientist Minimum Experience: • Minimum Requirement: Bachelor's degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience. • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Principal/Lead Bioinformatics Research Scientist. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude

Bioinformatics Scientist I

Philadelphia, PA
2024/04/13.

SHIFT: Day (United States of America ... Seeking Breakthrough Makers Children’s Hospital of Philadelphia (CHOP) offers countless ways to change lives. Our diverse community of more than 20,000 Breakthrough Makers will inspire you to pursue passions, develop expertise, and drive innovation. At CHOP, your experience is valued; your voice is heard; and your contributions make a difference for patients and families. Join us as we build on our promise to advance pediatric care—and your career. CHOP’s Commitment to Diversity, Equity, and Inclusion CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children. We strongly encourage all candidates of diverse backgrounds and lived experiences to apply. A Brief Overview The bioinformatics group in the Department of Biomedical and Health Informatics (DBHI) at Children’s Hospital of Philadelphia (CHOP) is seeking a Bioinformatics Scientist to join our team to support ongoing basic and translational research within the Center for Childhood Cancer Research (CCCR) and the Department of Anesthesiology and Critical Care Medicine. The candidate will be embedded in the laboratories of Dr. Caroline Diorio and Dr. Robert B. Lindell and will support scientific projects focused on immune dysregulation disorders related to infection, or due to cancers or cancer therapies. Major areas of focus will be CAR-T and cytokine release syndrome/immune effector cell associated neurotoxicity syndrome, and the immunologic phenotypes of sepsis. The candidate will attend lab meetings and interact daily with principal investigators and individual lab members. Additionally, the candidate will work with a principal investigator overseeing the bioinformatics group in the CCCR and our extended bioinformatics group in DBHI to stay current on emerging technologies and algorithms. The successful candidate will preferably have a MS degree in Bioinformatics, Computational Biology, or a related field, and must have demonstrable skills in coding in R and/or Python, though both are preferred. The successful candidate will have had biology training, experience with high-performance and/or cloud-based computing environments and will be expected to analyze data generated from proximity extension assays (i.e. Olink), bulk RNA sequencing, and multiparameter flow cytometry. Additionally, the successful candidate is expected to have experience with single cell RNA sequencing somatic single nucleotide variants (SNVs), indels, structural variations (SVs), fusion transcripts, or copy number analyses as well as experience in other types of bioinformatics analyses, particularly those involving next-generation sequencing. The successful candidate will have experience with established algorithms/pipelines processing genomics data, and the ability to learn and apply new methods. They will also be able to conceive and develop innovative solutions for a variety of computational challenges of these data and develop creative data visualizations. Strong communication, time-management, and presentation skills are essential. Knowledge of cancer biology and/or genomics is preferred. The Bioinformatics Scientist I position is an entry level position for a non-PhD level professional. The focus of the position is development, maintenance, and evolution of the tools that support management and analysis of genomic, proteomic, and other complex molecular data types. This includes the support of internal bioinformatics software, implementation and modifications of existing algorithms, and execution of routine tasks of limited complexity within the general area of bioinformatics analysis. The position allows for a wide variety of activities described within the job responsibilities and encompasses positions within both research and clinical environments. All activities occur with a moderate to high degree of supervision and the individual will rely on a high degree of peer-to-peer mentorship. The Bioinformatics Scientist I is primarily focused on the support of higher level bioinformatics personnel but may have minor direct interaction with collaborators and designees to resolve primarily technical issues and solutions. What you will do • Pre-Analysis (40%): Contributes to the maintenance and development of bioinformatics tool portfolio by developing knowledge of internally developed systems, open-source programs, and commercial applications. Provides efficient data management support. • Works with bioinformatics group members to develop functioning pipelines upstream of customized analysis workflows. • Maintains pipelines by staying current with evolving algorithms and standards and incorporating into pipeline. • Executes robust development testing for commonly used applications such as data processing pipelines. • Optimizes performance of applications by working with scientific computing and information systems groups to optimize hardware/software parameters. • Defines and prioritizes requirements for pipeline development over time to incorporate new technologies and platforms via functional communication with bioinformatics group members and bioinformatics end users. • Identifies appropriate open-source and commercial products that serve needs of pipeline and/or customized analyses of end users. • Implements and maintains commercial and open-source software for common bioinformatics and genomics data analysis. • Implements, updates and maintains locally stored data resources required for various analysis tasks. • Provides ad hoc support and one-on-one and group-based training on key bioinformatics software, features, and workflows. • Provides efficient data management support including file transfers, data formatting and manipulation, and basic integration of data from a variety of experimental and reference resources. • Develops and maintains working relationship with data providers such as sequencing cores within CHOP and infrastructure groups such as information systems. • Continually keeps abreast of evolving data generation platform fundamentals, file-specific information representation, and strategic application of code base to optimize value of data. • Maintains working knowledge of available commercial and openly accessible knowledge bases as they apply to bioinformatics analysis. • Coding (30%): Codes and generally supports both ad hoc, single task applications and larger pipeline applications that may combine multiple 3rd party and internally developed applications for genomics/proteomics/other complex data types and projects. • Implements, maintains, and regularly contributes to formal and bioinformatics group-centralized code management system. • Adopts appropriate forking and other strategies for robust code development. Apply to general bioinformatics group code base. • Adopts best practices for code development consistent with larger bioinformatics group. This includes choice of language based on the type of solution being developed, the likely life cycle and downstream usage of the resulting application, and integration with other systems. • Ensures that all routinely used tools (e.g. those included in shared analysis pipelines) are versioned and managed through a source control system. • Ensures that configuration files that provide parameters to algorithms and analysis software are versioned and managed through a source control system. • Develops and implements automated data-driven testing processes that test reproducibility of results between versions of pipeline software. • Develops and implements automated deployment processes that build and configure systems from source control repositories, eliminating the need to manually modify configuration files. • Regularly documents code, troubleshoot, and provide training when necessary. • Data Analysis (10%): Analyzes data of high complexity by applying sound statistical and commonly accepted bioinformatics methods to -omics data under supervision from mentors and peers. • Develops robust analysis plans under supervision. • Incorporates QA/QC in analysis workflows. • Delivers analytical endpoints such as feature identification, annotation, characterization, prioritization, etc. • Reports results using, primarily, spreadsheets and, secondarily, abstracted materials such as slides and visuals. • Collaboration (10%): Works with both bioinformatics group members and end users/clients to understand specific needs in bioinformatics and end user-specific domains. • Attends group and team meetings and contributes primarily factual information regarding processes and approach. • Defers to mentors and peers in establishing relationships, but works within boundaries to accomplish analytical goals. • Academic Output (10%): Contributes to presentations, grants, and manuscripts under supervision by mentors and peers. Education Qualifications • Bachelor's Degree Required • Master's Degree biological or computational discipline Preferred Experience Qualifications • At least one (1) year in applied bioinformatics, computational, and genomics/proteomics experience. Preferred Experience • Four (4) or more years of experience in applied bioinformatics, genomics, and computational work. • Knowledge of cancer biology and/or genomics. Skills and Abilities • Strong UNIX/LINUX expertise required. • Experience with R strongly preferred. • Experience with Python, Perl, or other languages preferred. • Experience with pipeline or workflow development frameworks preferred. • Experience with data management preferred. • Familiarity with open source and commercial bioinformatics resources and software preferred. • Experience with genomic data analysis preferred. • Experience or knowledge of technologies commonly used in biological labs, such as PCR, cloning, electrophoresis gels, and cell culture preferred. • Knowledge of the working mechanism of microarray, NGS, mass spectrometry, or other high-throughput technologies and awareness of their strengths and weaknesses, as well as applicability to a specific biological problem is preferred. • Familiarity with resources of genomic data sets and analysis tools, such as UCSC Genome Browser, Bioconductor, ENCODE, and NCBI databases is preferred. • Accountability and attention to timelines. • Excellent organization and communication skills with an emphasis on strong presentation skills. • Ability to work in a team environment. To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must be fully vaccinated against COVID-19 and receive an annual influenza vaccine. Learn more. Employees may request exemptions for valid religious and medical reasons. Start dates may be delayed until candidates are immunized or exemption requests are reviewed. EEO / VEVRAA Federal Contractor | Tobacco Statement

Bioinformatics Analyst

Charlottesville, VA
2024/04/13.

The Bioinformatics Analyst will work closely with the Spatial Biology Core (SBC) director (https://med.virginia.edu/spatial-biology-core/) to assist in the experimental design and analysis of research projects and provide expert consultation and technical/scientific support to UVA investigators. The SBC is seeking an Analyst to develop and establish computational methodologies and design... integrative data science approaches to study Spatial Multi-Omics analysis. The successful candidate will have a demonstrated ability to translate biological questions into technical design, and to identify, prioritize, and execute bioinformatics tasks to meet project goals and deadlines. The analyst will participate in meetings and consultations with clients to discuss design and interpretation and will assist in manuscript and grant preparation. The candidate should have a passion for bioinformatics and enjoy collaborating and supporting academic researchers and attending seminars and meetings. The successful candidate will be responsible for: • Organizing and managing Spatial data sets. • Manipulating and formatting data with R-package, Python, and Seurat tools. • Develop a pipeline to analyze Spatial context related to transcriptomics and proteomics data. • Using established open-source software and tools to assess quality and analyze data. • Running analyses on a high-performance computing cluster. • Using software or genome browsers for visualization. • Consulting with UVA investigators on experimental design, result interpretation, and grant and manuscript preparation. • May be asked to perform other duties as assigned. MINIMUM REQUIREMENTS Education: Master's or terminal degree Experience: Five years of specialized experience. Preferred Qualifications: • Ph.D. in Bioinformatics, Genomics, Biostatistics, Computer science or a related field. • M.S. + experience in bioinformatics or data science. • Advanced proficiency with R/Bioconductor or Python or C/C++. • Knowledge of database development and AI. • Experience with open-source software, tools, and databases for analyzing Spatial data analysis (GeoMx, CosMx, 10x Visium, Multiplex Analysis, etc.). PHYSICAL DEMANDS This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs. This is a restricted position and is dependent upon project need, availability of funding and performance. For more information on the benefits at UVA, visit https://hr.virginia.edu/benefits. This position will remain open until filled. The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment. TO APPLY Please apply through Careers at UVA, and search for R0055457. Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs'. Complete an application online with the following documents: • CV or Resume • Cover letter Applications that do not contain all required documents will not receive full consideration. References will be completed via UVA’s standardized process Skill Survey during the final phase of the interview process. For questions about the application process, please contact Jeremy Brofft, Senior Recruiting Specialist at xmf9ad@virginia.edu. For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/. The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician’s Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information

Applied Bioinformatics Research Scientist

United States (+1 other)
2024/04/13.

We are hiring an Applied Bioinformatics Research Scientist to identify metabolic vulnerabilities in lung cancer for therapeutic targeting. Lung Cancer is the most common cause of cancer deaths worldwide. Tyrosine kinase inhibitors and immunotherapy have been shown to be effective in a subset of patients; however, the overall survival rate for this disease remains low, especially for metastatic... disease. Moreover, small cell lung cancer (SCLC) patients have a poor prognosis, and there especially exists a gap in knowledge in understanding SCLC and identifying effective therapeutic strategies. The goal of our research team is to understand the underlying biology of key drivers in lung cancer by identifying metabolic vulnerabilities that can ultimately be used as single agents or combined with immunotherapy to target lung cancer therapeutically. Join our team of researchers who are funded through a P01 Program Project Grant! To learn more, click on the following link - https://www.moffitt.org/research-science/research-teams/lung-cancer-metabolism-working-group/faculty/ Position Highlights: • Work on unique, multi-omics datasets to support translational lung cancer metabolism research. • Develop cutting-edge methods for processing, analyzing, and interpreting multi-omics data. • Enjoy a close working relationship with bioinformaticians, statisticians, bench scientists, and translational researchers to establish a well-rounded multidisciplinary team. • Join an institute that highly values computational research. The Ideal Candidate: • Experience working with at least one “omics” type (e.g., DNA-seq, RNA-seq, metabolomics, proteomics). • Preference will be given to candidates with experience in integration of multi-omics data. • Programming experience in statistical program R and/or scripting languages such as Python/Perl on Unix/Linux systems. • Highly motivated and independent researcher with a background in cancer biology. • Excellent communication and writing skills. Responsibilities: • Supports the full life cycle of omics data: experimental design, data quality control, differential expression analysis, biological interpretation of results, and delivery. • Ensures timely and proper analysis of omics data generated by the team. • Maintains or develops new functionality for bioinformatics pipelines to analyze and visualize multi-omics data. • Collaborates on a variety of cancer and bioinformatics research projects. Credentials and Qualifications: • PhD in Bioinformatics, Data Science, Computational Biology, Machine Learning, Statistics/Biostatistics, or related fields. Moffitt Cancer Center is the only NCI Designated Comprehensive Cancer Center in Tampa, Florida. Tampa is an ideal choice for those seeking opportunities in a rapidly growing metropolitan city, which has become a hub for ground-breaking research. With its vibrant economy and diverse culture, Tampa Bay offers a unique blend of urban sophistication and natural beauty. Join the many who have already discovered what makes Tampa one of the fastest-growing metropolitan cities in the US. If you have the vision, passion, and dedication to contribute to our mission, then we have a place for you. How to Apply: Interested applicants should send a single PDF file that includes a cover letter summarizing their research training and accomplishments, a personal statement of scientific interests and goals, a current CV with recent publications, and contact information for three references to Drs. Xiaoqing Yu (xiaoqing.yu@moffitt.org) and Paul Stewart (paul.stewart@moffitt.org). Equal Employment Opportunity Moffitt is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, or protected veteran or disabled status. Moffitt seeks candidates whose skills, and personal and professional experience, have prepared them to contribute to our commitment to diversity and excellence

Bioinformatics Engineer

Indianapolis, IN
2024/04/13.

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We... give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company, focuses on the discovery of biologic, small molecule and genetic therapeutics for the treatment of diabetes, obesity and associated complications. The successful candidate will be responsible for supporting the data, tools and infrastructure that are critical for enabling clinical research objectives that will inform and accelerate the discovery and development of our next generation obesity therapeutics. Specifically, we are seeking a key multi-dimensional individual to integrate and analyze genomic, proteomic, metabolomic and phenotypic data from clinical trials on cloud based clinical multi-omics platforms. Are you interested in working on groundbreaking science? Apply today to join the Lilly Team! You will operate as part of a team of DOCTA early discovery scientists and clinicians, translational scientists, bioinformaticians and geneticists to: • Steward a secure and scalable cloud platform that enables clinical omics collaboration and is tailored to internal and external project needs • Develop, orchestrate, and maintain primary, secondary, and tertiary NGS analytical pipelines • Ingest and integrate large scale omics (genomics, proteomics, etc.) and phenotypic data and surface the data to scientists within DOCTA • Engage and collaborate with other scientists to develop and maintain workflows needed to process and analyze multi-modal data • Function independently within dynamic team-oriented environments and within cross-functional project teams as part of a multi-dimensional role Minimum qualifications: • Bachelors Degree in bioinformatics, computational biology, data science, data engineering, or other applied science with 5+ years of relevant work experience • Masters Degree in bioinformatics, computational biology, data science, data engineering, or other applied science with 3+ years of relevant work experience Additional Skills/Preferences • Experience implementing and deploying bioinformatics pipelines using software and data architectural standard processes in a distributed/cloud environment • Proven experience with AI/ML model development and/or bioinformatic applications through publication in a peer reviewed journal • Expertise in systems biology, bioinformatics, and genomics • Demonstrated communication (oral and written) skills and ability to work collaboratively in a team-oriented environment • Extensive experience in solving scientific problems using programming languages relevant to data analysis such as Python, R, Bash (shell scripting), etc. • Strong problem-solving skills and proven ability to troubleshoot issues Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly_Recruiting_Compliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response. Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups. #WeAreLilly

Bioinformatics Analyst

Lexington, KY
2024/04/13.

Requisition Number: RE44097 Working Title... Bioinformatics Analyst Department Name: 7H030:SANDERS-BROWN CTR ON AGING Work Location: Lexington, KY Grade Level: 46 Salary Range: $51,491-84,950/year Type of Position: Staff Required Education: MS Click here for more information about equivalencies https://hr.uky.edu/employment/working-uk/equivalencies Required Related Experience: No experience required. Required License/Registration/Certification None Physical Requirements May require long periods of sitting or standing and using a computer Shift Monday through Friday, 8:30am - 5:00pm. Job Summary We are currently seeking a skilled bioinformatics specialist to work full-time in a collaborative lab environment at the University of Kentucky. This position will collaborate with the Investigator, Co-Investigator, postdoctoral fellows, and students to develop, implement, and execute a variety of computational methods and tools across several contemporary multiplex technologies. This role will focus developing analysis pipelines to assess the neurobiological basis of aging and degenerative diseases in the CNS. Preference will be given for candidates with documented experience with computational biology, probabilistic models, statistics, machine learning, and discrete mathematics; ability to analyze and interpret complex datasets, such as multi-sample single cell RNAseq, CITE-seq, ATAC-seq, and bulk RNAseq studies. Expertise in standard bioinformatic tools using a variety of programming/scripting languages (e.g., R, Python, Perl, Java) in both Windows and UNIX environment is needed. Skills / Knowledge / Abilities Analytical, reasoning, and problem-solving skills; good understanding of computational biology, probabilistic models, statistics, machine learning, and discrete mathematics Does this position have supervisory responsibilities?: No Preferred Education/Experience Master's degree or Ph.D. in computer science or related field. University Community of Inclusion The University of Kentucky is committed to a diverse and inclusive workforce by ensuring all our students, faculty, and staff work in an environment of openness and acceptance. We strive to foster a community where people of all backgrounds, identities, and perspectives can feel secure and welcome. We also value the well-being of each of our employees and are dedicated to creating a healthy place to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors the University of Kentucky is a Tobacco & Drug Free campus. As an Equal Opportunity Employer, we strongly encourage veterans, individuals with disabilities, women, and all minorities to consider our employment opportunities. Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen

Associate Data Scientist Bioinformatics

Houston, TX
2024/04/13.

The primary purpose of the Associate Data Scientist is to leverage the capabilities of next-generation sequencing data to drive forward the discovery and development of novel therapeutics for cancer patients. This crucial role is centered on analyzing and interpreting intricate genetic information at the single-cell level to identify unique biomarkers and understand tumor heterogeneity. By... crafting advanced computational tools and algorithms, the Associate Data Scientist will play a crucial part in accelerating scientific discoveries and contributing to the development of new therapies and diagnostics that can transform patient care and health outcomes. Led by Prof. Bissan Al-Lazikani, Director of Therapeutics Data Science, the intelligent and ever-learning A3D3a platform is part of the new initiative in Therapeutics Data Science and part of our ambitious Institute for Data Science in Oncology at MD Anderson. A3D3a will accelerate the discovery and impact of novel therapies for cancer by enabling novel opportunities for optimized therapies for patients with a focus on rare and hard-to-treat cancers through the development of novel machine learning and AI technologies. JOB SPECIFIC COMPETENCIES • Carry out preparation, clean-up, and quality control of biological data, including scRNA-Seq, scATAC-Seq, Spatial transcriptomics and/or other multi-dimensional omic data modalities, • Develop and maintain pipelines for bioinformatics and statistical analyses of aforementioned data types; activities to include handling raw data, evaluating outputs, optimizing parameters and summarizing findings. • Collaborate with interdisciplinary teams to design experiments and analyze data from various single cell platforms. • Maintain knowledge of latest bioinformatic approaches and variety sequencing technologies, especially in single-cell context. • Present results at multidisciplinary project meetings. • Produce output for scientific publications and co-author said publications. • Prepare written reports, manuscripts, and grant applications with investigators. • Work closely with the team and collaborators to discover novel therapeutic opportunities for cancer patients. Expected Skills • Deep knowledge of bioinformatics tools and their implementation as part of pipelines, particularly for scRNA-Seq, scATAC-Seq, Spatial transcriptomics and/or other multi-dimensional omic data modalities. • Demonstrated experience and understanding of genomic technologies and analysis of data generated. • Analyzing and interpreting outputs to identify insights and hypotheses from data. • Understanding of essential statistical methodologies required for bioinformatics analyses. • Addressing challenges in bioinformatics as well as mitigation strategies such as bias, batch correction, etc. • Utilizing High Performance Computing to run large-scale analyses. • Unix, R, Python or other scripting/programming languages. • Other duties as assigned. COMPETENCIES • With Inclusion, you understand that your ideas and contributions are valued. You promote the same for others. You address your own biases while promoting diversity and equity. (Competencies: Cultural Humility, Cultural Awareness, Cultural Intelligence) • With Drive, you see that you can serve as a leader whether you have a formal leadership role or not. You tackle problems, move past setbacks and hardships, and don't lose sight of your goals. (Competencies: Self-Confidence, Analytical Thinking, Innovative Thinking, Technical Expertise) • You demonstrate Professionalism by setting the example for others and consistently modeling MD Anderson's values and service standards. You communicate effectively in a variety of ways. (Competencies: Inspire Trust, Oral Communication, Written Communication) • Through Emotional Intelligence, you maintain awareness of your own emotions and the emotions of those around you. Use nonverbal cues and feelings to engage others in an inclusive and responsive way. (Competencies: Active Listening, Teaming, Self-Reflection) • Having Coachability means you are engaged in relentless learning. You constantly ask questions and stay curious. You understand that the organization constantly evolves, and you should as well. (Competencies: Develop Oneself, Adaptability) Working Conditions Laboratory environment This position requires: Working in Office Environment ____No __X_ Yes Working in Patient Care Unit (e.g., Nursing unit; outpatient clinic) _X_ No ____ Yes Exposure to human/animal blood, body fluids, or tissues __X__No __ Yes Exposure to harmful chemicals __X__No ___ Yes Exposure to radiation _X_ No ____ Yes Physical Demands Indicate the time required to do each of the following physical demands: Time Spent Never 0% Occasionally 1-33% Frequently 34-66% Continuously 67-100% Standing X Walking X Sitting X Reaching X Lifting/Carrying Up to 10 lbs. X 10lbs to 50 lbs. X More than 50 lbs. X Pushing/Pulling Up to 10 lbs. X 10lbs to 50 lbs. X More than 50 lbs. X Use computer/keyboard X EDUCATION: Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field. Preferred: PhD in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field. EXPERIENCE: Required: Two years experience in scientific software development/analysis. Preferred: Experience with single cell sequencing analysis. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html Additional Information • Requisition ID: 166297 • Employment Status: Full-Time • Employee Status: Regular • Work Week: Days • Minimum Salary: US Dollar (USD) 85,000 • Midpoint Salary: US Dollar (USD) 106,500 • Maximum Salary : US Dollar (USD) 128,000 • FLSA: exempt and not eligible for overtime pay • Fund Type: Soft • Work Location: Hybrid Onsite/Remote • Pivotal Position: Yes • Referral Bonus Available?: Yes • Relocation Assistance Available?: Yes • Science Jobs: Yes #LI-Hybrid

Senior Bioinformatics Programmer

New York, NY
2024/04/13.

NYU Grossman School of Medicine is one of the nation's top-ranked medical schools. For 175 years, NYU Grossman School of Medicine has trained thousands of physicians and scientists who have helped to shape the course of medical history and enrich the lives of countless people. An integral part of NYU Langone Health, the Grossman School of Medicine at its core is committed to improving the human... condition through medical education, scientific research, and direct patient care. At NYU Langone Health, equity, diversity, and inclusion are fundamental values. We strive to be a place where our exceptionally talented faculty, staff, and students of all identities can thrive. We embrace diversity, inclusion, and individual skills, ideas, and knowledge. For more information, go to med.nyu.edu, and interact with us on LinkedIn, Glassdoor, Indeed, Facebook, Twitter and Instagram. Position Summary: We have an exciting opportunity to join our team as a Senior Bioinformatics Programmer. In this role, the successful candidate The Leon H Charney Division of Cardiology of the NYU School of Medicine is seeking a highly motivated, enthusiastic and creative individual to become part of a team of scientists investigating the genomic and epigenetic mechanisms of cardiovascular development and disease using computational approaches. The successful candidate will have the opportunity to work on various types of large datasets generated from next-generation sequencing methods including single-cell approaches and will interact with our experimental collaborators. The successful candidate will also interact with a vibrant group of bioinformaticians in the Applied Bioinformatics Laboratories (http://nyulmc.org/abl). ABL provides computational support and expertise to promote innovative cutting-edge research conducted by principal investigators at NYU Langone Health. This is a great opportunity to quickly acquire new skills, develop and publish new tools and methods, analyze challenging datasets and be a co-author in multiple studies. Job Responsibilities: • Perform other duties as assigned • Work closely with bench scientists to understand and help accomplish their research goals • Analyze various types of sequencing data analysis (e.g. RNA-seq, ChIP-seq, ATAC-seq, Hi-C-seq, bisulfite sequencing, whole-genome sequencing) • Perform robust data quality control and validation • Adapt genomic data analysis pipelines in a rapidly evolving research environment • Develop novel methods for multi-omics data analysis and integration • Integrate different types of genomics data and prepare concise presentations of computational results • Design, implement, execute standard pipelines for routine genomics data analyses, and customized pipelines for collaborative research projects Minimum Qualifications: To qualify you must have a Ph.D. or M.Sc. in Bioinformatics, System Biology, Computer Science or related field. Knowledge of biology and understanding of key and complex biological concepts (genes, pathways, cancer and/or stem cells). Ability to work independently while collaborating and assisting the team in its common research goals. Attention to detail and ability to work on multiple projects is necessary. Experience in Unix/Linux systems including HPC environments. Scripting languages: Python (preferred) or Perl. Statistical packages: R (preferred) or Matlab. 3+ years of experience with sequencing data (two of DNA-seq, RNA-seq and ChIP-seq). 3+ years of experience creating customized sequencing analysis pipelines. Excellent communication skills with proficiency in written and oral English. Qualified candidates must be able to effectively communicate with all levels of the organization. NYU Grossman School of Medicine provides its staff with far more than just a place to work. Rather, we are an institution you can be proud of, an institution where you'll feel good about devoting your time and your talents. NYU Grossman School of Medicine is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sex, sexual orientation, transgender status, gender dysphoria, national origin, age, religion, disability, military and veteran status, marital or parental status, citizenship status, genetic information or any other factor which cannot lawfully be used as a basis for an employment decision. We require applications to be completed online. If you wish to view NYU Grossman School of Medicine's EEO policies, please click here. Please click here to view the Federal "EEO is the law" poster or visit https://www.dol.gov/ofccp/regs/compliance/posters/ofccpost.htm for more information. NYU Langone Health provides a salary range to comply with the New York state Law on Salary Transparency in Job Advertisements. The salary range for the role is $81,325.15 - $116,600.00 Annually. Actual salaries depend on a variety of factors, including experience, specialty, education, and hospital need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits. To view the Pay Transparency Notice, please click here

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