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More Bioinformatics Jobs

Director, Bioinformatics Core

Boston, MA
2023/11/25.

When you join the growing BILH team, you're not just taking a job, you’re making a difference in people’s lives. Job Type... Regular Scheduled Hours: 40 Work Shift: Day (United States of America) About us: The BIDMC Bioinformatics Core (BBC) is part of the Precision RNA Medicine Core at Beth Israel Lahey Health. The BBC will be tightly integrated with the ‘Omics cores at BIDMC. It is the center for bioinformatics research expertise at BIDMC. We work directly with biomedical scientists across our Network and the Harvard community to implement best practice for analysis, interpretation, visualization, and dissemination of scientific discoveries using high dimensional data. The BBC team focuses on teamwork and we provide a supportive learning environment. About you: You understand the growing need for data driven research. You have a solid track record in bioinformatics service provision, excellence in communication skills and written and verbal reporting. A thorough knowledge of current and upcoming developments in analysis of high dimensional data, genomics and the current developments in bioinformatics are essential. Management skills should be evident, with a particular focus upon project management, the ability to define specific project requirements and to execute upon specifications. Evidence of having managed developers is of value. Publications should reflect a collaborative approach – with diversity of subjects being of interest. You should be able to articulate the vision of the program, and must be able to work independently. You are not shy of taking on core projects where you provide direct consulting, or work with teams to provide consulting to biomedical researchers. Your background is in biomedical/quantitative science with evidence of strong interest in working with researchers in diverse areas of biomedical research. You thrive on scientific challenges, enjoy collaborating with an interdisciplinary team and excel at communicating and coordinating between computational and wet-lab scientists. Learning and applying new methods is natural for you, and you are motivated to continuously expand your skills. You have superb data and project management skills. Working on different projects and deadlines, frequently in collaboration with other Cores and research groups, does not intimidate you. Job Description: Job Summary: The Bioinformatics Core Director will have strategic and tactical responsibility for the operations of the core, consultation, recruiting, overseeing core support staff and provision of leadership in developing core resources and providing research support and training for research faculty and staff at BIDMC. The Core Director will lead a team that develops and applies bioinformatics workflows for standard and custom data analysis across a broad range of technologies, such as single nuclei sequencing, spatial transcriptomics, genome variant analyses, transcriptomics or epigenomics. The Core Director is expected to create deliverables that could serve as standards for quality and innovation in broader communities, building informatics tools for data management, omics and imaging analyses within the reality of clinical data integration. The team will support researchers across the research community with their data management, quality control, analysis of data and presentation of results and will also be expected to coordinate selected research or support projects and act as an independent point of contact for researchers. Essential Responsibilities: 1. Determine BIDMC needs and work with core Scientific Directors in setting strategic, scientific and operational priorities. 2. Provide best practice bioinformatics services to investigators across campus, including pre-experiment/grant consulting, application and training on the use of bioinformatics core software tools, and integration of user-generated and large-scale public data sets. 3.Develop staffing plans and oversee recruitment; oversee developers as necessary, provide management of database design, interface design and information processing. 4. Co-ordinate a monthly seminar series, special trainings and mini-courses and organize user groups for bioinformatics related activities. 5. Develop and promote the funding model for expansion and sustainability of the core, including investments from organizational units around the community, charge-back models and collaborative grant applications to ensure long term sustainability. 6. Lead and collaborate on grant applications related to bioinformatics core projects. 7. Enable implementation of scalable workflows to disseminate analytical advances to the research community. 8. Engage with the community to both embrace and develop best practice. 9. Participate in leading national and international efforts aimed at establishing best practices and standards for omics basic science and potentially integration with clinical data representation and analysis. 10. Has full responsibility for planning, monitoring and managing department budget. Required Qualifications: Master's degree required; Doctoral degree preferred. 5-8 years related work experience required and 5-8 years supervisory/management experience required Demonstrated excellence in analytical, writing, and communication skills; A commitment to providing bioinformatics support for a broad range of scientific projects; Experience in developing and managing projects and people. Extensive knowledge of public domain bioinformatics data sources, public sequence databases, genomics tools, single cell analyses, and gene expression analysis. Evidence of software development experience and proficiency in scripting; Experience with SQL or other relational database systems, Unix and mixed operating systems environments, high-dimensional data management and analysis; Proficient in R and Bioconductor. Advanced skills with Microsoft applications which may include Outlook, Word, Excel, PowerPoint or Access and other web-based applications. May produce complex documents, perform analysis and maintain databases. Competencies: Decision Making: Ability to make decisions that are guided by general instructions and practices requiring some interpretation. May make recommendations for solving problems of moderate complexity and importance. Problem Solving: Ability to address problems that are varied, requiring analysis or interpretation of the situation using direct observation, knowledge and skills based on general precedents. Independence of Action: Ability to set goals and determines how to accomplish defined results with some guidelines. Manager/Director provides broad guidance and overall direction. Written Communications: Ability to communicate complex information in English effectively in writing to all levels of staff, management and external customers across functional areas. Oral Communications: Ability to verbally communicate complex concepts in English and address sensitive situations, resolve conflicts, negotiate, motivate and persuade others. Knowledge: Ability to demonstrate in-depth knowledge of concepts, practices and policies with the ability to use them in complex varied situations. Team Work: Ability to lead and direct multiple collaborative teams for large projects or groups both internal and external to the Medical Center and across functional areas. Results have significant implications for the management and operations of the organization. Customer Service: Ability to lead operational initiatives to meet or exceed customer service standards and expectations in assigned unit(s) and/or across multiple areas in a timely and respectful manner. Physical Nature of the Job: Sedentary work: Exerting up to 10 pounds of force occasionally in carrying, lifting, pushing, pulling objects. Sitting most of the time, with walking and standing required only occasionally FLSA Status: Exempt As a health care organization, we have a responsibility to do everything in our power to care for and protect our patients, our colleagues and our communities. Beth Israel Lahey Health requires that all staff be vaccinated against influenza (flu) and COVID-19 as a condition of employment. Learn more about this requirement. More than 35,000 people working together. Nurses, doctors, technicians, therapists, researchers, teachers and more, making a difference in patients' lives. Your skill and compassion can make us even stronger. Equal Opportunity Employer/Veterans/Disabled

Bioinformatician

Boston, MA
2023/11/25.

Bioinformatics and Molecular Data team is a growing group at the Informatics and Analytics Department (I&A) of Dana-Farber Cancer Institute (DFCI). The team addresses unmet needs for bioinformatics, data management, data mining and analysis across research, clinical, and operational units. It accelerates use of bioinformatics and data science methods, data, and tools within DFCI, bridging the gap... between research and clinical practice and helping design and implement operational solutions. The group encompasses expertise in bioinformatics, data science, machine learning, and software engineering. It works with some of the most prominent research and clinical DFCI programs, from basic research to translational research, to clinical diagnostics and operations. We look for an intelligent, hard-working, and dynamic individual to fill the role of Bioinformatics Scientist in the team. The successful candidate will support key initiatives relying on genomic data, have the ability to lead projects and potentially, in the future, may lead other people within the team. Specifically the role will work on an exciting new initiative to develop a cloud-based bioinformatics analysis platform. The platform will enable DFCI researchers to easily manage and analyze their genomic and biomedical data in the cloud environment, build and run analysis workflows and visualize the results. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The successful candidate will have proven experience in managing and independently executing complex bioinformatics tasks in the frame of Bioinformatics Workbench project. The role’s responsibilities will include: • Owning and leading various projects, serving as a subject matter expert. • Developing and implementing bioinformatics tools and pipelines in cloud environment. • Collaborating with DFCI software engineering and data science teams as well as interacting with external cloud and other technology vendors. • Meeting, consulting, and providing computational and informatics support to various DFCI scientists and independent faculty members in designing and executing key biomedical projects. • Collecting, analyzing, interpreting, and integrating complex biomedical data. • Delivering results for projects and generating relevant reports. • Working as a part of the broader team to identify and implement longer-term solutions that will improve quality, speed and efficacy of our current projects and programs through evaluating and benchmarking new software tools and pipeline development. • Contributing expertise to DFCI software code base and communities of practice. Minimum Education: Bachelor’s degree required in a STEM field. Master’s degree or PhD strongly preferred in bioinformatics, medical informatics, computational biology, statistics, computer science/engineering, or a related quantitative field. Minimum Education: 3 Years of experience required; Master’s degree with 1 year experience required; PhD with 0 years. • Deep bioinformatics skills at the interface between bioinformatics programming and understanding of biological and clinical problems. • Experience in analysis of the next generation sequencing data, e.g. WXS/WGS, RNA-Seq, etc; experience in single-cell and/or ctDNA data analysis is a plus. • Working knowledge of IA and machine learning approaches used in bioinformatics research • Experience in one or more areas of cancer research, including solid tumors, hematologic malignancies, patient-derived cancer models, biomarker discovery, etc. is a major plus. • Excellent communication and effective problem-solving skills, track record in serving a variety of diverse customers and projects. • Proven ability to work independently, prioritize, and manage people if needed, within an environment with evolving priorities. At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. EEOC Poster

Bioinformatics Scientist

Boston, MA
2023/11/25.

At Boston Children’s Hospital, the quality of our care – and our inclusive hospital working environment – lies in the diversity of our people. With patients from local communities and 160 countries around the world, we’re committed to reflecting the spectrum of their cultures, while opening doors of opportunity for our team. Here, different talents pursue common goals. Voices are heard and ideas... are shared. Join us, and discover how your unique contributions can change lives. Yours included. Job Summary Research Computing at Boston Children’s supports basic, translational, and clinical research by providing researchers with access to digital tools and technologies. Our computing environment consists of high-performance computing clusters, virtual machines, PetaByte-scale high-performance storage and cloud platforms. We work with BCH scientists to develop solutions in support of cutting-edge research ranging from lattice light-sheet microscopy to CryoEM, genomics, and informatics. The role will work with PhD-level bioinformatics scientists and researchers who have single-cell RNA-seq, single-cell ATAC-seq, spatial transcriptomics, bulk RNA-seq and ChIP-seq data to investigate the vascular complications of diabetics and other mouse and human diseases as well as with other pediatric scientists at BCH. The primary responsibilities will be building pipelines for the analysis, integration and sharing of these data. You will analyze, integrate different types of next-generation sequencing data and interpret the results and will have the opportunity to publish high-profile papers with prominent authorship depending on the intellectual contribution. The ideal candidate should have enthusiasm for developing collaborative relationships and a desire to foster the use of bioinformatics data in research studies. The Bioinformatics Scientist shall be responsible for: • Providing computational support services to Boston Children’s Hospital scientists and clinicians by applying a wide range of bioinformatics tools, methods and technologies. • With supervision and direction, completing assignments in the required timeframe while consistently adhering to standard operating procedures and best practices; adapting to a changing environment, resolving problems associated with assignments and seeking supervisor assistance when needed. • Participating and/or co-leading Research Computing projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectives. • Training staff and researchers; effectively tailoring presentations; developing, implementing and maintaining knowledge management systems. • Creating or contributing to a range of compelling communications (e.g. PowerPoint presentations, e-mails, memos, scientific presentations, and publications) that clearly deliver content; preparing communications appropriate for management and internal distributions. In order you qualify, you must have: • Minimum of 4-year Bachelor’s degree in STEM. Minimum of one year of advanced bioinformatics experience. Preference for candidates with a Ph.D. in Bioinformatics, Computational Biology or related. • Extensive knowledge of the use of bioinformatics computations in high-performance computing environments, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation, etc. • Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters. Cloud computing tools would be a bonus. • Strong publication record. Ability to effectively convey messages through written communication that are tailored to target audiences; meeting discussions and one-on-one verbal communications are clear and effective; ability to conduct effective meetings, to present in departmental and hospital forums and to develop training instructions and manuals. Boston Children’s Hospital offers competitive compensation and unmatched benefit, generous levels of time off, 403(b) Retirement Savings and Pension Plan. Experience the benefits of passion and teamwork. Please note: During a public health emergency, individuals in this role may be expected to take on additional duties to respond to organizational needs. Boston Children’s Hospital requires all employees to be vaccinated against COVID-19 and Flu, (unless you are eligible for a medical or religious exemption). Boston Children’s Hospital is an Equal Opportunity / Affirmative Action Employer. Qualified applicants will receive consideration for employment without regard to their race, color, religion, national origin, sex, sexual orientation, gender identity, protected veteran status or disability. Status Full-Time Standard Hours per Week 40 Job Category Information Technology Regular, Temporary, Per Diem Regular Office/Site Location Boston

Bioinformatics Analyst

Boston, MA
2023/11/25.

• Located in Boston and the surrounding communities, Dana-Farber Cancer Institute brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and... comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. • We seek an enthusiastic and highly motivated bioinformatics associate to join our cancer genomics research group. This individual will join oncologists, computational biologists and research scientists on our effort aimed at studying the relationships between cancer causing genomic alterations and clinical outcome. This position will provide ample opportunities for professional development and the acquisition of cutting-edge skills in basic and translational cancer genomics research, research planning and strategy, and data analysis and interpretation. • This individual will analyze cancer genomic data generated at Dana Farber using software tools within our team and by generating their own statistical analysis code. This individual will collaborate with oncologists, computational biologists and research scientist to study alterations in patients’ somatic genomes in order to assist in finding new cancer treatments and cures. • Works in teams with oncologists, research scientist and molecular biologists to define and execute computational approaches. • Performs computational analysis of next generation sequencing data, somatic copy number alterations, expression profiling, and biological pathways using in house algorithms. • Generates own code to conduct various other statistical analyses including those to discover relationships between cancer alterations and clinical correlates. • Presents data at project team meetings. • Assists in drafting of scientific manuscripts. • This employee will be located at both the Dana-Farber Longwood Medical Area campus and at the Broad Institute in Cambridge. At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. • Required: B.S./B.A. in the life sciences, physical sciences, or computational sciences. Some coding knowledge of either R, Matlab, and/or python. The ability to work in teams, excellent communication and data presentation skills. • Preferred: Background in molecular genetic data. Understanding of statistical methods and working in cloud computing and UNIX environments. • We will consider May 2024 graduates. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law. EEOC Poster

Principal Bioinformatics Scientist

Boston, MA
2023/11/25.

This is what you will do: As an integral part of Alexion’s Bioinformatics and Data Sciences team, your role involves creating and developing bioinformatics and data science solutions to advance the AAV gene therapy platform. You'll be part of a skilled team dedicated to generating strategic value and driving innovation throughout Alexion through the creative use of data sciences. You will need... to effectively collaborate with other colleagues at Alexion with diverse scientific backgrounds to deliver novel quantitative solutions and analyses. You will be responsible for: • The successful candidate will collaborate effectively with research teams and will own the development of computational solutions to design, develop, and optimize capsids and transgene cassettes for the novel AAV (adeno-associated virus) development. • Implement computational tools, lead experiment design, analyze studies/assays (such as DNAseq, RNAseq, Single Cell sequencing), interpret results, offer project projections, communicate findings, and uphold active program timelines. • Work both independently and as part of a collaborative team to apply innovative data analysis and AI/ML approaches • Develop software tools and scripts to support data analysis and interpretation pipelines. Practice reproducible research and version control in data analysis. • Lead efforts to identify key needs and questions that can be addressed using genetics, Omics or other bioinformatics approaches in collaboration with multi-functional research teams • Stay up-to-date with relevant scientific literature and incorporate new innovations into research activities and evaluation of new technologies and methods You will need to have: • PhD (or equivalent degree) in computational biology, bioinformatics, human genetics, genomics, systems biology, bioengineering, or a related field, with strong background in data science and machine learning, 5+ years of related experience (including post-doc experience) • Significant experience in AAV design and engineering • Solid training and experience of machine learning/ artificial inteligence/ network modeling, strong programming skills in R and/or Python and familiar with Unix/Linux and high-performance computing environments • Proven track record in the analysis, visualization, and interpretation of genetics and Omics data • Strong knowledge of human genetics, molecular biology, as well as biological pathways and networks • Be able to work independently with both internal and external diverse team stake holders and contributors • Excellent communication and presentation skills with specific experience in cross functional collaborations.. • The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees will, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours. We would prefer for you to have: • Familiarity with concepts, tools and data formats used for sequence analysis, protein structure modeling and integration of diverse -omics datasets • Familiarity with computational protein modeling and structural biology AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements. AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law. Expectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum of four days per week from the office. But that doesn’t mean we’re not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world

Bioinformatics Scientist

Boston, MA
2023/11/25.

***LOCAL CANDIDATES ONLY. NO RELOCATION OR SPONSORSHIP AVAILABLE FOR THIS ROLE.***Pay: $65-77/hour Details: 1 Year Contract... Qualifications: Work location is either Boston or Cambridge MA, Education Minimum Requirement: • Ph.D. in Bioinformatics, Biostatistics, Computational biology, Computer Science, Genetics, Immunology, Mathematics, Molecular Biology, Statistics, or related field • Masters degree in the above disciplines, with 3 years of relevant experience • B.S with 6+years of relevant experience. Required Experience and Skills: • Passion to solve biological problems and identify problems that can be efficiently solved through computational methods and algorithms. • Experience with computational analysis and biological interpretation of diverse large-scale NGS experimental datasets • Proficiency in at least one statistical programming language, such as R or Python • Familiarity with public databases, and repositories of DNA, RNA and single cell profiling data • Skilled at integrating results generated from multiple omics data sources, and biological knowledge bases to customize analytical approaches for discovery research. • Interest in identifying novel applications of AI / machine learning strategies for biological target discovery. • Demonstrate the ability to learn, be proactive and motivated, and consistently focus on details and execution. • Excellent oral and written communication skills P • Previous experience with experimental design of biological assays, statistical hypothesis testing, and biological interpretation • Understanding the pros and cons of various algorithms for DNA-seq, RNA-seq, single-cell RNA-seq and/or functional genomics data • Experience with version control environments, such as Git • Experience with high-performance Linux cluster and cloud computing Responsibilities: The Data, AI & Genome Sciences department is looking for a passionate and talented computational biology scientist to join our Computational Biology and Genomics research team for a contract role based in Cambridge / Boston, MA. In this role, you will apply machine learning and bioinformatics approaches to analyze large multi-scale and multi-omics datasets in collaboration with cross-functional teams of computational biologists, data scientists and colleagues in Discovery Research to support target discovery and drug development efforts. Oncology research is driven by a deep interest in the biology of tumor and its microenvironment, and how diverse points of intervention can be combined to achieve ever higher rates of durable response and patient overall survival. In this exciting role, you will: * Contribute to multiple stages of drug discovery to decode genetic dependencies and identify therapeutic targets by interrogating high-throughput assays, including genomics, transcriptomics, and proteomics datasets. * Collaborate with experimental scientists across functions to characterize novel targets coming from genetics, translational and disease pathway exploration, explore target engagement, research mechanisms of action, and provide functional validation of novel drug targets. * Work with large internal and public biological data sets including Next Generation Sequencing (NGS) data (e.g. RNA-Seq, Perturb-Seq, single cell RNA-Seq, WGS, CRISPR) * Be proactive and work collaboratively across disciplines, including molecular biologists, protein scientists, bioinformaticians, and software engineers. * Employ best reproducible research and data integrity practices to generate reusable analysis frameworks and reports to support Discovery Oncology target identification and validation efforts

Bioinformatics Software Engineer

Boston, MA
2023/11/25.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute (DFCI) brings together world renowned clinicians, innovative researchers and dedicated professionals, allies in the common mission of conquering cancer, HIV/AIDS and related diseases. Combining extremely talented people with the best technologies in a genuinely positive environment, we provide compassionate and... comprehensive care to patients of all ages; we conduct research that advances treatment; we educate tomorrow's physician/researchers; we reach out to underserved members of our community; and we work with amazing partners, including other Harvard Medical School-affiliated hospitals. The Department of Informatics and Analytics (I&A) at Dana-Farber has multiple openings for highly motivated bioinformatics software or data engineers who are passionate about the potential for molecular data to inform clinical care of cancer patients and the groundbreaking discoveries that are a product of genomic data integration and analysis. The qualified candidate will work on an exciting initiative to build a cloud-based bioinformatics analysis platform. The platform will enable researchers at DFCI to easily manage their genomic and biomedical data in the cloud environment, select and kick off containerized NGS analysis workflows, monitor the execution status and eventually visualize the results. The successful candidate is expected to collaborate with functional teams such as Bioinformatics and Data Engineering, and cloud and other technology vendors. • Integrate a wide variety of tested computational tools and pipelines into cloud environment • Actively participate in designing scalable, highly available, secure, cost-effective cloud-based solutions • Collaborate with bioinformaticians and engineers to containerize new or existing analysis pipelines and make pipelines portable on both on-prem high-performance computing and cloud environments • Design, implement, and maintain scalable pipeline workflows to automate multi-step computing tasks required for various data analysis scenarios • Develop and maintain the automated tests and monitoring process to ensure the successful pipeline execution and deployment • Assist product management for the documentation of the system requirements, design, and troubleshooting • Provide technical support to end users for pipeline deployment and execution • Apply industry best practices and act as an advocate for coding standards and test-driven development • Mentor new team members Qualifications: • Bachelor’s degree required, MS preferred, in Bioinformatics, Computational Biology, Data Science, Computer Science, Software Engineering, or related discipline • Demonstrated proficiency with Python, R, Perl and/or other languages • Experience with data analysis in cloud environment, especially Microsoft Azure • Proficient with Linux environment, shell scripting, and command line tools • Experience with software development and Agile process is a strong plus SKA’s: • Enthusiastic about data security, process automation, and innovation • Familiar with distributed code versioning tools such as Git, GitHub, Bitbucket • Detail oriented with ability to gain deep understanding of technical systems • Excellent interpersonal skills, passionate about innovative solutions • Familiarity with bioinformatics workflow management such as Cromwell and Nextflow Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other groups as protected by law. EEOC Poster

Bioinformatics Intern

Baltimore, MD
2023/11/18.

Company Overview: Labcorp is a global leader of innovative and comprehensive laboratory services that helps doctors, hospitals, pharmaceutical companies, researchers and patients make clear and confident decisions. We provide insights and advance science to improve health and improve lives through our unparalleled diagnostics and drug development laboratory capabilities. The company’s more than... 60,000 employees serve clients in over 100 countries, worked on over 80% of the new drugs approved by the FDA in 2022 and performed more than 600 million tests for patients around the world Global Internship Program: Exciting opportunity to be part of the Labcorp 2024 Global Internship Program as a Bioinformatics Intern! As a Labcorp intern, you will have the opportunity to support meaningful assignments that compliment an education in STEM+ Business and Healthcare disciplines, and are inspiring and valuable in our mission to improve health and improve lives across the globe. In addition to department work, we support your professional development and career exploration through program workshops, leadership speakers, employee resource group introductions, new hire panel discussions and small group ‘coffee chats’. Capitalize on a dedicated training and development program that will support your scientific and professional career aspirations, and take pride in delivering work that helps save the lives of millions of people around the world. About the Team: • Personal Genome Diagnostics (PGDx), a part of LabCorp, is Empowering the Fight Against Cancer by unlocking actionable information from the genome. We are developing an innovative portfolio of tissue-based and non-invasive liquid biopsy genomic products for laboratories worldwide. • The Bioinformatics and Data Science team is a multidisciplinary team of engineers and scientists providing bioinformatics and data science support for the Oncology portfolio. Internship Assignment Summary: • Support evaluation of bioinformatics pipelines and software • Contribute to technical documentation • Learn development processes in an agile • Familiarize yourself with genomics results for precision oncology products Education/Qualifications/Skills: • Working towards bachelor’s degree in Life Sciences, Bioinformatics, Computer Science or a related field • Proficiency working with data and/or software, experience working with next-generation sequencing data and/or tooling preferred • Has experience delivering multiple projects in an academic or professional setting • Ability to collaborate with various stakeholders Labcorp is proud to be an Equal Opportunity Employer: As an EOE/AA employer, Labcorp strives for diversity and inclusion in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications of the individual and do not discriminate based upon race, religion, color, national origin, gender (including pregnancy or other medical conditions/needs), family or parental status, marital, civil union or domestic partnership status, sexual orientation, gender identity, gender expression, personal appearance, age, veteran status, disability, genetic information, or any other legally protected characteristic. We encourage all to apply. For more information about how we collect and store your personal data, please see our Privacy Statement

Associate Bioinformatics Data Scientist

Houston, TX
2023/11/18.

SUMMARY The University of Texas MD Anderson Cancer Center in Houston is one of the world's most respected centers focused on cancer patient care, research, education and prevention. It was named the nation's No. 1 hospital for cancer care in U.S. News & World Report's 2022-2023 rankings. It is one of the nation's original three comprehensive cancer centers designated by the National Cancer... Institute. The Genetics Department is a basic science department located in the George and Cynthia Mitchell Basic Sciences Research Building at the world-renowned University of Texas MD Anderson Cancer Center in the heart of the Texas Medical Center. The focus is on advancing knowledge of the molecular genetic mechanisms that regulate normal and abnormal cellular processes. The primary purpose of the Associate Data Scientist position is to provide bioinformatics analysis of next generation sequencing (NGS) data for faculty across the institution, to process NGS data for Advanced Technology Genomics Core facility, to perform quality control (QC) analysis and to maintain QC metrics and sample records of NGS experiments on the servers, and to meet with faculty to review data analysis results. This position impacts cancer research projects by developing/maintaining programs and applications tailored to meet research objectives and makes them available to the wider cancer research community. The ideal candidate will have working experience in: • Analyzing genomic and epigenomic data. • Proficiency in at least one programming language such as R, Python, or PERL. • Experience in NGS data analysis (expression profiling, mutations and structural variations, and differential peak analysis), data integration, and data mining. KEY FUNCTIONS • Performs bioinformatics analysis of bulk RNA-Seq and scRNA-Seq datasets in terms of gene expression profiling analysis. • Performs bioinformatics analysis of DNA-Seq and scDNA-Seq in terms of detection of both mutations and structural variations. • Performs bioinformatics analysis of ChIP-Seq, ATAC-Seq, and scATAC-Seq datasets in terms of genome wide profiling of histone modifications and chromosome accessibility. • Develop software pipelines to perform standard NGS data analysis routine in an automated fashion. • Perform quality control (QC) analysis on NGS data, and maintain QC metrics and sample records of NGS experiments on the servers. • Work with bioinformatics faculty, IT personnel, and other researchers to respond to new technologies. Other Skills • Expertise in programming languages such as Python, PERL, or R. • Expertise in linux/unix based environments. • Excellent communication skills and team-working attitude will be essential. • Other duties as assigned. EDUCATION Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field. EXPERIENCE Required: Two years of experience in scientific software development/analysis. Preferred: • Analyzing genomic and epigenomic data. • Proficiency in at least one programming language such as R, Python, or PERL. • Experience in NGS data analysis (expression profiling, mutations and structural variations, and differential peak analysis), data integration, and data mining. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html Additional Information • Requisition ID: 163498 • Employment Status: Full-Time • Employee Status: Regular • Work Week: Days • Minimum Salary: US Dollar (USD) 75,000 • Midpoint Salary: US Dollar (USD) 94,000 • Maximum Salary : US Dollar (USD) 113,000 • FLSA: exempt and not eligible for overtime pay • Fund Type: Soft • Work Location: Onsite • Pivotal Position: Yes • Referral Bonus Available?: No • Relocation Assistance Available?: Yes • Science Jobs: Yes #LI-Onsite

Bioinformatics Technologist II- Ross Lab

Port St. Lucie, FL
2023/11/18.

Join Cleveland Clinic Weston Hospital’s team of caregivers that remain on the leading edge of technology and education all while consistently providing patient-centered healthcare. As part of Cleveland Clinic’s Florida region, Weston Hospital is recognized as one of the top hospitals in the Miami-Fort Lauderdale metro area and Florida. Here, you will work alongside passionate and dedicated... caregivers, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world. As a Bioinformatics Technologist II, you will develop and maintain software systems and pipelines for data processing and analysis of next generation sequencing data. You will work in a highly collaborative environment as part of a team of software engineers, computational biologists, and clinical and basic research scientists. The ideal caregiver is someone who: - Has experience with manipulation and analysis of high volume biological data. - Has experience with commonly used software tools for biological sequence analysis. - Has basic understanding of molecular biological concepts. - Has written and verbal communication skills. - Has teamwork and motivational skills. - Has organizational and multitasking skills. At Cleveland Clinic, we know what matters most. That's why we treat our caregivers as if they are our own family, and we are always creating ways to be there for you. Here, you'll find that we offer: resources to learn and grow, a fulfilling career for everyone, and comprehensive benefits that invest in your health, your physical and mental well-being and your future. When you join Cleveland Clinic, you'll be part of a supportive caregiver family that will be united in shared values and purpose to fulfill our promise of being the best place to receive care and the best place to work in healthcare. Job Description Responsibilities: • Support existing production pipelines, fix and resolve issues, as needed. • Identify, evaluate, and apply new computational methodologies and emerging technologies to improve existing methods and tools. • Analyze genomics data in partnership with experimental and computational team members, industry partners and collaborators. • Assist other lab members (graduate students, postdoctoral fellows) with training on bioinformatic tools. • Other duties as assigned. Education: • Bachelor’s degree in computer science/software engineering/bioinformatics or related field + 3 years of related experience. • Masters degree in a similar field may offset up to two years of work experience. Languages: • Language required • Language preferred Certifications: • None required Complexity of Work: • Requires critical thinking skills, decisive judgment, and the ability to work with minimal supervision. • Must be able to work in a stressful environment and take appropriate action. Work Experience: • Must possess a minimum of 3 years of relevant experience . Advanced degrees in related fields may offset 2 years of work requirement. • Experience in DNA and RNA-seq data analysis. Experience with single-cell RNA sequencing data is a plus. • Solid understanding of all stages of software development cycle. Familiarity with agile software development approach is a plus. • Fluency in programming languages (Java, Python, Perl, R), UNIX shell scripts and database management systems (MySQL or PostgreSQL). • Experience with common bioinformatics tools (BWA, Bowtie, SAMtools, GATK, MuTect, VarScan, Strelka, STAR). • Proficiency with Linux/UNIX tools in high-performance computing clusters (HPC) environment. Experience with Cloud Computing is a plus. • Excellent presentation and communication skills. Physical Requirements: • Ability to perform work in a stationary position for extended periods. • Ability to travel throughout the hospital system. • Ability to operate a computer and other office equipment. • Ability to communicate and exchange accurate information. Personal Protective Equipment: • Follows standard precautions using personal protective equipment. Pay Range Minimum hourly: $30.41 Maximum hourly: $46.38 The pay range displayed on this job posting reflects the anticipated range for new hires. While the pay range is displayed as an hourly rate, Cleveland Clinic recruiters will clarify whether the compensation is hourly or salary. A successful candidate's actual compensation will be determined after taking factors into consideration such as the candidate's work history, experience, skill set, and education. This is not inclusive of the value of Cleveland Clinic's benefits package, which includes among other benefits, healthcare/dental/vision and retirement

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