Bioinformatics Jobs

About Formic Labs To accelerate life science, we are building an "OS" that will help investigators design, execute, interpret, manage, and scale experiments, from wet lab assays to bioinformatics analyses, multiscale simulations, and interactive data visualizations. Our platform will supercharge biomedical scientists by providing investigators with approachable, integrated, scalable, and... collaborative access to the sea of data, methods, and tools. By enabling scientists to focus on science, our platform will transform industry, academic, and government R&D. Furthermore, we will use our platform to address one of the grand challenges of biology, developing holistic mechanistic simulations of entire cells and tissues that explain phenotype from genotype. • Simplify R&D by relieving investigators of the technical and time-consuming minutiae of designing, executing and managing protocols, such as installing and maintaining tools, learning APIs to tools, converting formats, and setting up workflow engines and data warehouses in HPC and cloud systems. • Integrate R&D such as by helping investigators find diverse methods and tools across historical silos and link them together. • Facilitate deeper and more holistic investigation such as by easing complex multi-step protocols that integrate diverse tools, large screens over millions of conditions, and analyses of large data sets. • Increase the reliability of R&D by transparently, faithfully, and reproducibly executing protocols and automatically organizing and capturing the provenance of their results. • Promote collaboration by making tools, protocols, and their results easy to share. • Boost methods and tool development by providing tool developers a marketplace to reach users. • Reduce the cost of R&D by reducing the need for custom engineering. Led by Michael Antonov, a co-founder of Oculus, and well-funded by Formic Ventures, Formic Labs is poised to accelerate basic science, medicine, and bioengineering. Job summary The product manager will champion the roadmap for the bioinformatics portion of our platform, gathering the needs of bioinformatics investigators and working with our science and engineering teams to translate their needs into a transformative a SaaS platform that enhances their productivity: • Research and understand our users' needs across industry, academia, and government • Communicate to prospective users how our platform could solve their problems • Design the requirements of our platform, our launch strategy, and each aspect of our users' experience • "Roadmap" or catalog that defines all of the bioinformatics methods and tools that our users could employ • "Driving directions" that help users find appropriate tools for specific projects and combine them into workflows • Low-code graphical editor for combining tools into workflows • Backend services for executing workflows and collecting their results • Interactive visualizations for exploring the inputs and outputs of workflows • Management and collaboration tools such as that help users track the progress of their runs and share workflows and runs with team members • Guide the product to the finish line, such as by drafting timelines, organizing meetings, and getting stakeholders to agree to solutions • Continuously advocate for our users by constantly exploring opportunities to enhance and expand our product, including after launch Requirements Must haves • Passion for accelerating biomedical science and engineering • Ability to translate the needs, wants, and motivations of biomedical scientists and engineers into accessible solutions • Strong understanding of bioinformatics methods, tools, formats, and platforms • Experience defining complex products and directing their functionality • Ability to lead a cross-functional team of scientists and engineers to bring our product to market • Ability to work with this team to establish and manage processes for research, development, launch, monetization, support, etc. • Ability to establish a strong communication channel with prospective customers and users in our target market to understand their needs and communicate our vision • Excellent organizational, communication, and leadership skills Nice to haves • Knowledge of drug discovery and/or microbial engineering • Knowledge of data integration, modeling and simulation, and/or data visualization • Knowledge of workflow management tools such as CWL and Galaxy Location Formic Labs is located in South San Francisco, CA. The employee may split their time between in-person and remote work. We will reimburse the employee for relocation. We prefer candidates who want to work with our team in person, but we will consider exceptional remote candidates located in the US. Benefits This position offers competitive salary, benefits, and equity

Create Your Career With Us! Sanford Health is one of the largest and fastest-growing not-for-profit health systems in the United States. We're proud to offer many development and advancement opportunities to our nearly 50,000 members of the Sanford Family who are dedicated to the work of health and healing across our broad footprint... Facility: Imagenetics Building Location: Sioux Falls, SD Address: 1321 W 22nd St, Sioux Falls, SD 57105, USA Shift: Day Job Schedule: Full time Weekly Hours: 40. 00 Department Details Flexibility with remote work; if working remote full time, travel to Sioux Falls will be required. Job Summary Manage and apply resources to general bioinformatics and medical informatics operations, guided by experience, organizational goals and operational strategies. Also responsible for the management of cyclical projects. Work on complex computational bioinformatics matters where analysis of issues, data and process require advanced specialist knowledge and in-depth industry and technical knowledge. Contribute to the development of genomic clinical assays and their required validation (i.e. polygenic risk scores) Oversee the computational bioinformatics and medical informatics team within the Imagenetics program across the enterprise. Collaborate with medical genetics lab leadership, the technology solutions team and many others. Train, supervise and mentor members of the bioinformatics and medical informatics team. Oversee bioinformatics pipelines for genetic data including planning, quality control, and project specific analyses. Address the technical performance of the various experiments, especially for the array data, by comparing raw, quantile, cubic spline and rank invariant for each experiments. For RNA Sequence data, assist with splice variant analysis and single nucleotide polymorphisms (SNP)/copy number variation (CNV) analysis. Familiarity with security and privacy requirements applicable for working with patient data in a medical environment and in the development of appropriate ethically and legally compliant policies Qualifications Bachelor s degree in bioinformatics, computer science or related field. Advanced degree in bioinformatics, medical informatics or related field preferred. Minimum five years of related experience in bioinformatics, medical informatics or a closely related field required. Two years in a managerial or leadership position and a demonstrated record of mentoring preferred. Experience in the analysis of high-throughput DNA and RNA sequencing data, including alignment, quality measurements, variant calling, variant annotation, variant prioritization, incidental findings reporting, and transcript quantification is required. Computational experience is to include demonstrated database management, process management, next generation sequence analysis, and presentation of data to clinicians. Preference will be given to individuals with expertise in database vitalization, genetic/epigenetic analyses and medical and/or research informatics experience. Benefits Sanford Health offers an attractive benefits package for qualifying full-time and part-time employees. Depending on eligibility, a variety of benefits include health insurance, dental insurance, vision insurance, life insurance, a 401(k) retirement plan, work/life balance benefits, sick leave and paid time off. To review your benefit eligibility, visit . Sanford is an EEO/AA Employer M/F/Disability/Vet. If you are an individual with a disability and would like to request an accommodation for help with your online application, please call 1- or send an email to . Sanford Health has a Drug Free Workplace Policy. An accepted offer will require a drug screen and pre-employment background screening as a condition of employment. Req Number: R- Job Function: Research Featured: No

Description SUBFUNCTION DEFINITION: Bioinformatics applies biology, computer science, data science, and statistics to analyze and interpret biological and clinical data... REPRESENTATIVE RESPONSIBILITIES •Informatics Curates, annotates and organizes various types of biomedical data (e.g., genomic, clinical, imaging, sequencing) in various formats (e.g., flat files, relational and non-relational databases). Collects and records appropriate metadata. Ensures data are securely stored yet highly accessible to authorized users. •Data Analysis Executes pipelines for curating, processing and analyzing biomedical data of various types (e.g., genomic, clinical, imaging, sequencing). Utilizes existing software to support complex data management tasks (e.g., sequence alignment, variant calling, inter-sample comparison, patient matching/linkage). Utilizes web-based bioinformatics tools and public/proprietary relational databases. Follows standard operating procedures. Works in collaboration with both technology and scientific teams. •Requirements Gathering Interfaces with clinicians/researchers to collect requirements of basic to moderate complexity including user workflows. Contributes to problem-solving and solution evaluation. •Software Evaluation & Development Contributes to the evaluation and development of software solutions to support basic to moderately complex data workflows. Under general supervision, assists with implementation and testing efforts. Effectively communicates the status of all efforts to necessary parties. Utilizes project and time management skills to complete projects within specific timeframes. •Publication Contributes to analyses and publications. Generates reports and figures for publications. Assists with materials for publications and scientific meetings. Works closely with biostaticians on the production of publication and presentation materials. Qualifications EDUCATION/EXPERIENCE Required: •Bachelor's degree in a related field • 0 - 2 years of work experience in a related job discipline Preferred: Unique Skills

Bioinformatics Analyst - Data Scientists Job ID: req1171... Employee Type: exempt full-time Division: Bioinformatics and Computational Science Facility: Rockville: 9605 MedCtrDr Location: 9605 Medical Center Drive, Rockville, MD 20850 USA The Frederick National Laboratory is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable problems in the biomedical sciences in cancer and AIDS, drug development and first-in-human clinical trials, applications of nanotechnology in medicine, and rapid response to emerging threats of infectious diseases. Our core values of accountability, compassion, collaboration, dedication, integrity, and versatility serve as a guidepost for how we do our work every day in serving the public's interest. Position Overview: PROGRAM DESCRIPTION The Frederick National Laboratory is dedicated to improving human health through the discovery and innovation in the biomedical sciences, focusing on cancer, AIDS and emerging infectious diseases. With leading science and technology, the laboratory performs basic research, supports clinical trials and drug development, develops and applies next-generation technologies to solve applied problems while serving as a national resource of high-tech facilities, while also effectively responding to emerging health threats. The Bioinformatics and Computational Science (BACS) directorate works collaboratively and helps to fulfill the mission of Frederick National Laboratory in the areas of biomedical informatics and data science by developing and applying world leading data science and computing technologies to basic and applied biomedical research challenges, supporting critical operations, developing and delivering national data resources, and employing leading-edge software and data science to effectively enable and advance clinical trials. The Strategic and Data Sciences Initiatives group in BACS works collaboratively to continue to accelerate cancer research with a focus on increasingly effective use of data and scalable computing while guiding development of future computational infrastructure and workforce capabilities needed to address key cancer research challenges. KEY ROLES/RESPONSIBILITIES Bioinformatics Analyst • Responsible for the analysis of bioinformatics data through the use of machine learning techniques, computational methods, and cloud resources to facilitate analysis such as next generation sequencing, functional genomics data, drug data, natural language processing, molecular dynamics simulations, and image processing • Provides expertise and guidance for data integration and data aggregation across multiple data types and data sources • Contributes with educational material and expertise for training initiatives across the program • Contributes to development and testing of data science workflows implemented on High Performance Computing and Cloud systems BASIC QUALIFICATIONS To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below: • Bachelor's, Master's or PhD from an accredited college or university according to the Council for Higher Education Accreditation in areas related to life science, computer science, data science, or biomedical informatics. (Additional qualifying experience may be substituted for the required education), and • Experience working in clinical/bioinformatics projects with a strong background in programming (e.g. Python, R, Perl, bash) • Working knowledge of bioinformatics methods and data formats (e.g., NGS, medical images, NLP, structural biology, molecular dynamic simulations, etc. ) and experience working with Ph.D. and M.D. researchers • Hands-on experience working with various life sciences research data and metadata including proteomics, genomics, image analysis, and clinical data • Self-motivated and willing to learn and explore technology • Must be able to obtain and maintain a security clearance PREFERRED QUALIFICATIONS Candidates with these desired skills will be given preferential consideration: • PhD preferred with degree in life sciences, computational sciences, or data sciences • Experience with application of machine learning / deep learning methods for medical data • Experience with cloud environment e.g. AWS, Azure or Google Cloud • Knowledge of scientific workflows development (e.g. Snakemake, Nextflow, CWL, etc.) • Experience with use of containers (e.g., Docker, Singularity, etc.) This position description does not represent a specific job but represents a sourcing announcement for current and future open positions. Our positions span a wide range of skills, so candidates who express an interest may be considered for upcoming positions at Frederick National Laboratory for Cancer Research. Equal Opportunity Employer (EOE) | Minority/Female/Disabled/Veteran (M/F/D/V) | Drug Free Workplace (DFW) #readytowork

Position Summary The Principal Bioinformatics Scientist will be conceptualizing, designing, and taking a leading role in our product development teams with bioinformatics pipelines and analysis towards better and more affordable cell and gene therapy, personalized medicine solutions. Resilience is looking for smart, motivated scientists who enjoy taking on complex challenges, work well in an... agile, dynamic environment, and care about high-quality products and best practices. The ideal candidate thrives on the applications of NGS data analysis (in particular using AI and ML) and is passionate about learning. Resilience rewards initiative, curiosity, a bias for action, a problem-solving attitude, and a desire to bring innovative, simplified solutions to complex problems that ultimately impact patient care. Responsibilities • Algorithm development – Design, prototype, and implement computational algorithms to analyze multi-omics datasets, including large variant calling, Small VC, proteomics, or RNA analysis. Provide technical and strategic leadership to the methods and product development team. • Product development – Collaborate deeply with inter-disciplinary teams to research, develop, and implement algorithms in production-grade software. Provide strong scientific and technical project leadership in the biomanufacturing innovation area, including research and development roadmap coordination. • Leadership – Partner with senior management to develop and oversee new multi-omic analysis pipelines, features, and bioinformatic workflows that support key business objectives and strategies. Qualifications • BSc/MS: 15+ years of experience or Ph.D.: 10+ years of experience in a scientific-analytical field, e.g., computer science, bioinformatics, data science, computational biology. • 10+ years experience in a development environment for increasingly complex analytical intensive products. • Experience with product development life cycle (requirements, agile development, regulatory frameworks) is a must. • Experience in high-performance computing and cloud computing (AWS). • Experience developing products from early-stage concept to volume manufacturing. • Experience leading and mentoring teams required. • Experience in bioinformatics applications to Immunology is a plus. • Experience with microbial genomes is a plus. • Expert knowledge in Python, R, C#, C++, Java, or other common programming languages. • Proficiency in SQL databases. • Good knowledge of software design principles including git, docker, and markdown documentation. • Expert in computational biology, analysis of NGS data, and data analysis is a must. • Ability to motivate, mentor, and inspire a high-capacity technical team. • Excellent organizational skills; Able to manage multiple fast-paced projects simultaneously. • Ability to communicate effectively and professionally across various technical disciplines with a broad slate of stakeholders, including management, peers, customers, and suppliers

The University of Nevada, Reno is recruiting for a Bioinformatics Scientist to support researchers at the University of Nevada and in the Western IDeA states, by providing biostatistics and bioinformatics services for individual research projects. Tasks of the Scientist include, establish proper survey methods and experimental designs for specific projects; apply standard biostatistical methods... to large experimental data sets; utilize standard bioinformatics databases and tools to identify and classify components of a biological system; create mathematical/statistical models to examine whole-omics data; use and develop statistical and computational pipelines to analyze omics data such as RNA-seq, 16s rRNA, ChIP-seq, scRNA-seq, bisulfite sequencing, and high-throughput proteomics (DIA and TMT). Successful applicants are not expected to be proficient in all of these areas. Successful candidates will have proficiency in Linux environments and experience in R and/or Python, a thorough understanding of and interest in biology, the ability to rapidly learn new concepts, attention to detail, strong organizational, problem-solving, and communication skills, ability to work in an environment that is collaborative, innovative, data-driven, and goal-oriented. Required Qualifications Bachelor’s Degree in the fields of biological and/or computational sciences and two (2) years of related work experience; OR a Master’s Degree in the fields of biological and/or computational sciences and one (1) year of related relevant work experience; OR a Doctorate Degree in the fields of biological and/or computational sciences with no post-graduate work experience required. Related Experience: bioinformatics and/or biostatistics or related Preferred Qualifications Bioinformatics is often associated to genomics and transcriptomics, as Core Labs support all omics data. Scientists with a proteomics background are encouraged to apply

Postdoctoral positions to study spatiotemporal regulation of CD4 T cell effector function The Fowell lab focuses on mechanisms of CD4 effector function, in situ, in inflamed and infected tissues. We utilize intravital multiphoton imaging, optogenetics and single cell analysis to determine context-specific cues that enhance or regulate CD4 T cell effector function (Th1, Th2, Tfh). Postdoctoral... positions are available for a number of projects, including but not limited to: Determining how the inflammatory milieu in infected tissues shapes the transcriptional and epigenetic programming of effector function Development of spatial transcriptomics approaches to determine how tissue location impacts function in infected tissues Positional cues (chemokines, ECM, pathogen foci) that regulate the entry, retention and exit of effector T cells at inflamed sites using optogenetic models to mark T cells in time and space. Meet the Fowell Lab, https://www.fowelllab.org Qualifications and CompensationApplicants must have a Ph.D., M.D., D.V.M., or equivalent advanced degree. Prior immunology experience is preferred, but not essential. Candidates with imaging or bioinformatics expertise who are looking to apply quantitative tools to the study of immune responses in health and disease are encouraged to apply. The PI is committed to supporting the candidate’s career development and research progress, including the exploration of new project areas and collaborations. Competitive salaries are set above the NIH guidelines, with excellent benefits. Highly Dynamic and Multidisciplinary EnvironmentSuccessful postdocs will join a highly collaborative research group within the Department of Microbiology and Immunology and the Cornell Center for Immunology. The positions offer the chance to contribute to a multidisciplinary and cutting-edge research community with opportunities to collaborate closely with experts in immunology, bioinformatics and biomedical engineering, including advanced hyperspectral and 3-photon imaging programs. Diversity and InclusionFor over 150 years Cornellians have been striving to create a welcoming and inclusive learning environment. Ezra Cornell’s founding principles stipulate that Cornell is an institution for “… any person … any study,”. In support of this founding principal, we strongly encourage under-represented minorities and persons from marginalized communities to apply. The University has a Dual Career program to assist candidates and their partners with career searches.Ithaca is “Gorges”Cornell University is located in Ithaca NY, in the heart of the beautiful Finger Lakes region of New York State. The Ithaca area offers over 150 waterfalls and is one of the premier wine regions of the US bosting over 100 wineries.How to ApplyPlease send a cover letter and curriculum vitae to Dr. Deborah Fowell, djf273@cornell.edu

When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals. Staff Scientist, Bioinformatics... South San Francisco, CA | Clinical Next-Generation Sequencing Division How will you make an impact? You will be an integral part of an enthusiastic and dedicated team of scientists, engineers working towards cutting edge scientific solutions in Bioinformatics of Next Generation Sequencing (NGS). What will you do? • Representing software in program core team and interacting with colleagues from diverse functions such as molecular biologist, algorithm developers and product manager. Able to translate custom needs to software product requirements and product specifications. Able to track project timelines and complete all needed documentations. • Developing test plans and test cases to verify and validate software product requirements and specifications. • Algorithm testing for NGS data analysis pipelines. • Developing verification tools to increase testing automation coverage. • Troubleshooting for build deployment, resource management, and job scheduling and analysis pipeline. • Leading a project and driving the project to completion. Education: MS. or higher in Computer Science/engineering, Bioinformatics, Biomedical engineering, Statistics, EE or related fields, and 5+ Years related experience. Experience • Diverse knowledge and experiences of developing NGS applications. • Experiences of bioinformatics tools and algorithms used in NGS analysis. • Experiences in software design and development. Good understanding of software testing best-practices. • Software development skills and experience with Java, Python, Perl with 5+ year experience. • Strong expertise on Linux/Unix environment. • Experiences of relational database. Knowledge, Skills, Abilities • Demonstrated leadership in leading project completion. Good communication skills with scientists, engineers and software developers. • Must be detail oriented and self-driven. Desired Qualification: • Java programming skills in highly desired. • Hands-on experience with software automation testing. ACCESSIBILITY/DISABILITY ACCESS Job Seekers with a Disability: Thermo Fisher Scientific offers accessibility service for job seekers requiring accommodations in the job application process. For example, this may include individuals requiring assistance because of hearing, vision, mobility, or cognitive impairments. If you are a job seeker with a disability, or assisting a person with a disability, and require accessibility assistance or an accommodation to apply for one of our jobs, please submit a request by telephone at 1-855-471-2255*. Please include your contact information and specific details about your required accommodation to support you during the job application process. • This telephone line is reserved solely for job seekers with disabilities requiring accessibility assistance or an accommodation in the job application process. Messages left for other purposes, such as not being able to get into the career website, following up on an application, or other non-disability related technical issues will not receive a response

The Position Roche Sequencing Solutions (RSS), a business within Roche Diagnostics, is focused on developing a disruptive Next-Generation Sequencing (NGS) platform along with a portfolio of reagents, assays and informatics solutions for multiple disease areas. We are looking for a Principal Bioinformatics Scientist I/II to support assay development efforts. In this role, you will apply your... strong background in next-generation sequencing data analysis, clinical diagnostics, and molecular biology to analyze sequencing data aimed at developing laboratory methods and algorithms for IVD assays. You will collaborate closely with molecular biologists, software engineers and bioinformatics scientists to create products that will impact patient care for many years to come. RESPONSIBILITIES • Partner closely with molecular biology, engineering, and other bioinformatics teams to perform all aspects of bioinformatics data analysis including experimental design, data collection, QC, algorithm design, analysis & visualization, and communication of results. • Serve as bioinformatics functional representative on project teams providing input and guidance on bioinformatics related matters. • Recommend next steps for bioinformatics pipeline and laboratory workflow protocols to meet product development objectives. • Transfer new products to production teams and provide scientific support for on-market products. • Present and communicate project updates across multiple functions in the organization. • Create documentation of bioinformatics deliverables for scientific, marketing, and regulatory purposes. QUALIFICATIONS • PhD in Bioinformatics, Computational Biology, Computer Science, or Statistics, or other quantitative field combined with 4+ years experience analyzing large complex genomic datasets, or equivalent combination of education and experience. • Demonstrated experience delivering sequencing based clinical diagnostic products supporting both laboratory technology and bioinformatics pipeline development. • Prior experience developing RUO & IVD products is preferred. • In depth knowledge of sequencing molecular biology, bioinformatics tools, statistical methods, and cancer biology. • Proficient with programming languages (R, Python, Java) in a distributed Linux environment. • Skilled in data analysis and visualization techniques. • Hands-on experience using a workflow management system such as Nextflow or Snakemake. • Result-oriented individual that thrives in collaborative multi-disciplinary teams. Excels at incorporating feedback in a professional manner. • Strong written and verbal communication skills with ability to adjust to technical and non-technical audiences. • Committed to delivering high quality clinical products. Who We Are At Roche, we are passionate about transforming patients’ lives, and we are bold in both decision and action - we believe that good business means a better world. That is why we come to work every single day. We commit ourselves to scientific accuracy, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. Are you seeking a meaningful job? Then come aboard! Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law. Who we are At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity. Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated against COVID-19 in accordance with customer requirements, the company’s health and safety obligations and/or applicable law or guidelines. Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law. If you have a disability and need an accommodation in connection with the on-line application process, please email us at US.Accommodation@roche.com. Job Level: Individual contributor

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of... the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines. We are looking for a Senior Bioinformatics Scientist to join our Bioinformatics team. Your work will focus on development of new data acquisition and analytics approaches to be incorporated in future iterations of Nautilus instrumentation. To that end, you will work together with the Platform Integration experimental team to support all phases of research from ideation through proof-of-concept. The role is highly collaborative; success is measured by the degree to which you elevate the capabilities of your peers in pursuit of scientific insight. Frequent activities in this role include consulting with experimentalists on experimental design, implementing data visualizations and statistical approaches to answer key experimental questions, building pipelines to automate common analysis tasks, and designing databases to organize experimental data and enable longitudinal analysis. This role reports to the Associate Director of Bioinformatics and is based in San Carlos, CA