Bioinformatics Jobs

About GREGoR Stanford Site : GREGoR Stanford Site (GSS), is one of 6 sites in the National Institutes of Health (NIH)’s Genomics Research to Elucidate the Genetics of Rare disease (GREGoR) Consortium. The GSS (https://gregor.stanford.edu/) mission is to provide a platform for functional genomics research and validation to improve diagnosis in Mendelian disease through integrated analysis of... multi-omics data. GSS is led by co-PIs Dr. Stephen Montgomery (Department of Pathology), Dr. Matthew Wheeler (Division of Cardiovascular Medicine) and Dr. Jon Bernstein (Division of Medical Genetics). At GSS, research participants who remain undiagnosed after exome sequencing will undergo short read and long read genome sequencing, transcriptome sequencing, methylation assays, metabolomics and/or lipidomics assays. State-of-the art computational algorithms and new methods will be applied and developed to prioritize the variants and genes. The data will be analyzed in a secure and scalable manner using a HIPAA compliant cloud platform like AnVIL and Google Cloud Platform (GCP). Novel causal variants and genes will be validated through state-of-the-art targeted approaches including massively parallel reporter assays, induced-pluripotent stem cell assays and CRISPR engineered cellular and mouse models. About the Position: We are seeking a highly talented and motivated Bioinformatics Engineer to support our GSS pipeline and data analysis team. Your role will focus on the development of pipelines and tools for comprehensive analysis of large amounts of molecular data generated by the GSS, with special emphasis on genomics, transcriptomics, and metabolomics datasets. You will also establish and support cloud infrastructure for storage and computation of the multi-omics data. Your ability to understand biological experiments, strong experience in the analysis of large-scale biological datasets, proficiency with programming languages and experience in high-performance computing environments or cloud will be a key resource in enabling high-quality data to flow through our systems to enable diagnosis and discovery of new disease-gene associations. A complete application will include CV and cover letter. Duties include: Collect, manage and clean datasets. Employ new and existing tools to interpret, analyze, and visualize multivariate relationships in data. Create databases and reports, develop algorithms and statistical models, and perform statistical analyses appropriate to data and reporting requirements. Use system reports and analyses to identify potentially problematic data, make corrections, and determine root cause for data problems from input errors or inadequate field edits, and suggest possible solutions. Develop reports, charts, graphs and tables for use by investigators and for publication and presentation. Analyze data processes in documentation. Collaborate with faculty and research staff on data collection and analysis methods. Communicate with government officials, grant agencies and industry representatives. • – Other duties may also be assigned Desired Qualifications: Bachelor’s degree in Mathematics, Statistics, Computer Science or related field. Research experience in computational biology desired; specifically in analysis of high-throughput, multiplexed and multi-omics data. Experience in designing data analysis pipelines is an advantage. Proficiency in Python and/or R and Linux bash scripting. The candidate should be able to work independently, be highly motivated, well organized, adaptable and work well within a highly interdisciplinary and international team. Good communication and interpersonal skills as well as fluent English are essential, as well as proficient computer skills (Mac and PC). Education & Experience (Required): Bachelor’s degree or a combination of education and relevant experience. Experience in a quantitative discipline such as economics, finance, statistics or engineering. Knowledge, Skills and Abilities (Required): Substantial experience with MS Office and analytical programs. Strong writing and analytical skills. Ability to prioritize workload. Physical Requirements*: Sitting in place at the computer for long periods of time with extensive keyboarding/dexterity. Occasionally use a telephone. Rarely writing by hand. Tagged as: Data Science

Summary Become a key team member of a translational research team... investigating neurological disease. The successful candidate will develop and optimize innovative analytic pipelines to integrate multiple types of high-throughput genomics, transcriptomics, and proteomic data. The successful candidate will be working closely with cross-functional projects with scientists and medical experts from diverse expertise. Job Duties Generic Duty: Carry out binformatics analyses and provide computational supports. Specific position duty: • Evaluate, process, and analyze high throughput datasets, including RNA, ChIP, WGBS, proteomics, single-cell data, etc. • Develop, optimize, and maintain analysis pipelines for reproducible analyses. • Prepare reports and meet with collaborators to present the analytical methods or findings. • Work closely with other collaborators in the cross-functional team. • Assist with drafting and completing manuscripts for publication and grant proposals. Minimum Qualifications • Bachelor's degree in Genetics, Biology, Bioinformatics, Biostatistics, Computational Biology, Computer Science, or a related field. • No experience required. Preferred Qualifications • Master’s degree in a related field. • Experience with bioinformatics algorithms, analytical pipelines and large-scale data analysis. • Good understanding of statistics, machine learning. Deep learning experience is a plus. • Experience in machine learning, deep learning algorithms, natural language processing, large-scale multi-modal data. • Proficiency in scientific programming with R, Python, Perl or equivalents. • Strong communication and scientific reporting skills (verbal, written, and graphical). • Strong organizational, prioritization, and time management skills with explicit attention to details. • Creative, open-minded, critical reasoning, and passionate about scientific research. • Effectively collaborative and motivated by challenges. • Experience in bioinformatics and knowledge of machine learning. • Strong communication and scientific reporting skills. • Creative, open-minded, strong critical reasoning, and passionate about scientific research. Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza. Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer. 15225 SN; CH

ElevateBio is a cell and gene therapy technology company built to power the development of transformative cell and gene therapies today and for many decades to come. The company has assembled industry-leading talent, built world-class facilities, and integrated diverse technology platforms necessary for rapid innovation and commercialization of cell, gene, and regenerative therapies. The... Role ElevateBio is seeking a motivated Bioinformatics Intern to join the Next Generation Sequencing Team at ElevateBio. A successful candidate will process bioinformatics, NGS, and cloud computing knowledge from coursework or hands-on experience. This position is responsible for executing and analyzing established bioinformatics processing pipelines in AWS. This position will also be responsible for performing follow-up analyses alongside the team’s Bioinformatic Scientists. This is an exciting opportunity to join a dynamic organization and make significant contributions on internal cell and gene therapeutic programs. Here’s What You’ll Do • Help execute and monitor established bioinformatics processing pipelines (e.g., whole genome/exome sequencing, methylation sequencing, amplicon sequencing, etc.) in AWS • Perform follow-up analyses (e.g., variant annotation, methylation detection, etc.) • Assist in the testing and development of novel bioinformatic analyses • Assist with data transfer and version control • Attend and present findings at team meetings Requirements • Must be in a college or university program with a focus in Bioinformatics, Computational Biology, Computer Science, or a closely related field • Hands-on experience or coursework in bioinformatics, cloud computing (AWS, HPC, or other), and NGS data (DNA, RNA) is preferred • Experience with coding (R, Python, or SQL) and version control is preferred. • Ability to multi-task on multiple projects simultaneously • Willing to learn, excellent team player with good communication skills Why join ElevateBio? ElevateBio is accelerating the future of biotechnology; developing the next-generation of cell, viral and regenerative medicine therapeutics for the treatment of severe diseases. We have launched a revolutionary new model that integrates innovators, infrastructure and capital to effectively develop cell, gene and related therapies for patients with severe and life-threatening disorders. With plans for a cutting-edge laboratory and manufacturing center already underway, we're building a world-class organization lead by expert talent with bench-to-bedside capabilities. At the heart of the ElevateBio platform is ElevateBio Base Camp, a state-of-the-art research, development and manufacturing center for innovation in the Greater Boston Area to be staffed with a world-class team of scientists. Our Vision Next-generation product development for advanced therapies supported by global bench-to-bedside expertise shared across our portfolio of companies ElevateBio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. ElevateBio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law

Senior Scientist Skin Biology & Bioinformatics WL1C... Background Be part of the world’s most successful, purpose-led business at Unilever. Work with brands that are well-loved around the world, that improve the lives of our consumers and the communities around us. We promote innovation, big and small, to make our business win and grow. Our portfolio ranges from nutritionally balanced foods to indulgent ice creams, affordable soaps, luxurious shampoos and everyday household care products. We produce world-leading brands including Lipton, Knorr, Axe and Hellmann’s alongside trusted local skin care and cleansing names and innovative-forward thinking brands such as Dove, Vaseline, Murad and Dermalogica. The Science and Technology pillar in Unilever is charged with the delivery of breakthrough technologies and differentiated innovations to meet the needs of our consumers around the world, developing new functional ingredients and claims for our leading brands. As part of this, Human Biology is a Beauty and Personal Care Platform, investigating the biological mechanisms that underpin key consumer phenotypes such as skin aging, dry skin, and sensitive skin. An opportunity has arisen in the Science & Technology -Human Biology team for a qualified scientist to join at our R&D Center located in Trumbull, Connecticut, USA. The role is ideally suited to an energetic, self-motivated, resourceful research scientist with ability to work on their own initiative and with strong people and communication skills. Expertise in molecular and/or cell biology essential while experience in computational biology/bioinformatics is strongly preferred. Key Responsibilities • Design and execute research experiments,perform data analysis and insight generation to support Innovation projects/activities in the Skin Rejuvenation Programme. • Continuously develop broad knowledge in skin aging following current literature and attending scientific conference to advance research programmes and capabilities and fill technology pipeline. • Manage data integration and insight extraction from large transcriptomic, epigenetic, and proteomic datasets. • Actively evaluate new analysis, modeling, and experimental methodologies and establish relevant capabilities within our program. • Leverage the best of both academia and industry, including assessing and working with independent service providers, to support the generation of new insights and development of novel technologies. • Document procedures and results in compliance with Electronic Notebook guidelines • Prepare verbal and written status reports Skills/Experience/Qualifications • APhD degree or Master’s degree with 3+ years relevant experience in Cell Biology, Molecular Biology, Computational Biology/Bioinformatics, or a related discipline • Expertise in molecular & cellular biology, tissue engineering, or regenerative medicine and most preferably in skin biology. • Extensive experience with mammalian cell culture, preferably skin cells. Experience with standard biochemical and molecular biology techniques, including RNA isolation, qPCR, microscopy, ELISAs, and/or quantitative protein analysis. • Ability to design and executeexperiments in cellular in vitro models, particularly skin cells, is required and highly desired in higher order models. • In-depth knowledge of common bioinformatic tools such as those for differential gene expression analysis, gene set enrichment analysis,pathway analysis and visualization (e.g. IPA) • Aptitude for communicating complex biological and computational concepts to non-scientists is essential. Capable of presenting scientific results to multidisciplinary teams and key stakeholders. • Strong work ethic and self-motivated with ability to work independently and as a member of highly collaborative team • Excellent time and project management skills and ability to work on multiple projects Work Level 1C: Pay: The pay range for this position is $83,200 to $124,700. Unilever takes into consideration a wide range of factors that are utilized in making compensation decisions including, but not limited to, skill sets, experience and training, licensure and certifications, qualifications and education, and other business and organizational needs. Bonus: This position is bonus eligible. Long-Term Incentive (LTI): This position is LTI eligible. Benefits: Unilever employees are eligible to participate in our benefits plan. Should the employee choose to participate, they can choose from a range of benefits to include, but is not limited to, health insurance (including prescription drug, dental, and vision coverage), retirement savings benefits, life insurance and disability benefits, parental leave, sick leave, paid vacation and holidays, as well as access to numerous voluntary benefits. Any coverages for health insurance and retirement benefits will be in accordance with the terms and conditions of the applicable plans and associated governing plan documents. ------------------------------------ Unilever is an organization committed to diversity and inclusion to drive our business results and create a better future every day for our diverse employees, global consumers, partners, and communities. We believe a diverse workforce allows us to match our growth ambitions and drive inclusion across the business. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability. For more information, please seeEqual Employment Opportunity Postersopens in a new window Employment is subject to verification of pre-screening tests, which may include drug screening, background check, credit check and DMV check. If you are an individual with a disability in need of assistance at any time during our recruitment process, please contact us at NA.Accommodations@unilever.comopens in a new window. Please note: This email is reserved for individuals with disabilities in need of assistance and is not a means of inquiry about positions or application statuses

Senior Bioinformatics Software Developer Company Description... Personalized immunotherapies are the future of the fight against cancer, and IsoPlexis (www.isoplexis.com) is Making the Difference in enabling the lofty goal of employing immunotherapies to combat our toughest diseases. Our integrated systems, named #1 Innovation by Scientist Magazine & World-Leading Design by Red Dot, are changing cancer research by connecting biological readouts to what is actually happening in patients. Our game changing hardware technologies, originally from Cal Tech and Yale, combined with our next generation software and data visualizations, are powered by our amazing R&D team and used throughout the world. We work with a growing list of leading researchers who are publishing findings that connect our readouts to what is truly happening in patients, and that excites & drives all of us to do more! If you like working at the intersection of biological sciences and healthcare, and you enjoy intellectually challenging yet fulfilling projects, give us a call. Our fast growing, 300+ person team has a sense of integrity, energy, and urgency to ‘make things happen’ in our collective careers and in the broader world, and we look forward to talking. Responsibilities • The Software Developer’s main responsibility will be to help develop, test, and implement IsoPlexis’s custom image analysis software for the Duomic project. • Development of image processing algorithm prototypes with the ability to convert them into commercial-grade C/C++ modules for use in a manufacturing setting. • Collaborating with multiple groups, spanning from optics engineers to biologists. Skills/Qualifications • Strong algorithm development skills in the field of image analysis and computer vision • Experience with OpenCV • Analyze and verify software application performance through data analysis and measurements • Comfortable working with C++ • Experience with clang-tidy, clang-format, or other static analysis tools • Experience with CMake • Experience with CI/CD pipelines • Excellent communication skills with the following: interdepartmental (mechanical, biologists, software, system engineers) • Proactive, analytical thinking, excellent problem solving and communication skills • Optional: experience with Python ISOPLEXIS is only considering applicants who have valid authorization to work in the U.S., in this position, for the Company. ISOPLEXIS does not sponsor employment-based visas for this position Job Type: Full-time Required education: • Bachelor's degree or higher in Computer Science, Engineering, Physics, Applied Mathematics or related fields Industry Experience: • 3+ years Their company has offices in Branford. They have a large team that's between 201-500 employees. You can view their website at http://isoplexis.com

Research Computing at Boston Children’s supports basic, translational, and clinical research by providing researchers with access to digital tools and technologies. Our computing environment consists of high-performance computing clusters, virtual machines, PetaByte-scale high-performance storage and cloud platforms. We work with BCH scientists to develop solutions in support of cutting-edge... research ranging from lattice light-sheet microscopy to CryoEM, genomics, and informatics. The role will be responsible for providing routine as well as leading-edge support for researchers who have single-cell RNA-seq, single-cell ATAC-seq, spatial transcriptomics, bulk RNA-seq, ChIP-seq and methylation data to investigate human genetics and cortical development and other human and mouse diseases as well as with other pediatric scientists at BCH. The primary responsibilities will be building pipelines for the analysis, integration and sharing of these data. The candidate will analyze, integrate different types of next-generation sequencing data and interpret the results and will have the opportunity to publish high-profile papers with prominent authorship depending on the intellectual contribution. They should have enthusiasm for developing collaborative relationships and a desire to foster the use of bioinformatics data in research studies. The Bioinformatics Scientist Shall Be Responsible For • Providing computational support services to Boston Children's Hospital scientists and clinicians by applying a wide range of bioinformatics tools, methods and technologies. • With supervision and direction, completing assignments in the required timeframe while consistently adhering to standard operating procedures and best practices; adapting to a changing environment, resolving problems associated with assignments and seeking supervisor assistance when needed. • Participating and/or co-leading Research Computing projects with other members from the BCH research community; setting goals and objectives for projects and demonstrating achievement of those goals and objectives. • Training staff and researchers; effectively tailoring presentations; developing, implementing and maintaining knowledge management systems. • Creating or contributing to a range of compelling communications (e.g. PowerPoint presentations, e-mails, memos, scientific presentations, and publications) that clearly deliver content; preparing communications appropriate for management and internal distributions. To Qualify You Must Have • Minimum of 4-year Bachelor's degree in STEM. Minimum of one year of advanced bioinformatics experience. Preference for candidates with a Ph.D. in Bioinformatics, Computational Biology or related. • Extensive knowledge of the use of bioinformatics computations in high-performance computing environments, including open-source bioinformatics software and pipelines to support diverse bioinformatics analyses such as single-cell RNA-seq, bulk RNA-seq, ChIP-seq, methylation, etc. • Extensive knowledge of technologies used in support of biomedical research, such as programming languages (R and Python), databases (SQL), version control (Git), scientific workflow tools and high-performance computing clusters. Cloud computing tools would be a bonus. • Strong publication record. Ability to effectively convey messages through written communication that are tailored to target audiences; meeting discussions and one-on-one verbal communications are clear and effective; ability to conduct effective meetings, to present in departmental and hospital forums and to develop training instructions and manuals. Boston Children’s Hospital offers competitive compensation and unmatched benefits

Company Description Quantum-Si is pioneering a new generation of technology to create the market of Next Generation Protein Sequencing (NGPS). Similar to Next Generation DNA Sequencing (NGS), which gave us a blueprint of what could happen by studying our DNA, NGPS enables an unbiased view of the proteome through improved scale, resolution, and sensitivity leading to better understanding of... disease and improved general health. We operate at the intersection of biochemistry, chemistry, hardware, molecular biology, photonics, semiconductor chips, and software with a goal to drive a digital transformation of a $44 billion dollar proteomics market. Join us on the journey to transform healthcare, motivated by the idea that the products you work on will change the lives of millions of people around the world. Job Description We are seeking a highly motivated and experienced Bioinformatics Lead to join our growing team. The successful candidate will play a critical role in designing, developing, and implementing innovative bioinformatics solutions to support R&D and develop customer facing applications. The lead will help define the applications that are enabled by Quantum-Si’s sequencing technology and develop the bioinformatics capabilities necessary to deliver those applications. There will be significant interaction with the Algorithms team to provide feedback on signal processing and the Data Science team to define the features of the data that need to be characterized for use in applications. This role will also be a liaison to the Product Marketing team in building out the roadmap for product releases on the platform. This will initially be an individual contributor role making technical contributions in application and workflow development with the plan to build a team in the future. As part of our team, your core responsibilities will be: • Lead the design and development of bioinformatics tools and pipelines used by R&D and customers to analyze single-molecule protein sequencing data • Build software that derives biological insights from protein identity, protein abundance, and post-translational modifications using large, complex proteomics data sets • Define the content and format of data, reports, and metrics for each application • Collaborate closely with and communicate results to the algorithms and data science teams in order to improve software and system performance • Collaborate with the product marketing team to determine scope and timeline of applications released to customers • Stay current on the latest bioinformatics technologies and apply them to solve complex problems • Author external white papers, technical notes, journal publications and conference posters • Build a world class team of bioinformaticians that are proteomics experts Qualifications Baseline skills/experiences/attributes: • M.S. or Ph.D. in Bioinformatics, Computational Biology, Electrical Engineering, or physical science • Minimum of 8 years postgraduate experience working in Bioinformatics • Expert in bioinformatics algorithms for sequence analysis, such as alignment and variant detection • Experience with proteomics applications for protein identification, protein quantitation, and post-translational modification detection • Strong programming skills and development of large software development projects in Python and a compiled programming language, e.g. C, C++, C#, or Java • Previous technical management experience • Good software development practices of source control, code reviews, and testing • Experience with analysis and visualization of either proteomics or genomics data • Demonstrated ability to solve challenging technical problems and think critically • Excellent communication and leadership skills, with the ability to work effectively in a cross-functional team environment Ideally, you also have these skills/experiences/attributes (but it’s ok if you don’t!): • Experience developing and using bioinformatics software for protein mass spectrometry • Experience deploying software in a cloud environment • Experience with time series data • Wet lab experience in order to facilitate interactions with our multidisciplinary team You Deeply Identify with Core Quantum-Si Values: • Team: We are stronger as a unit and collectively committed to the goal and each other. • Accountability: Be accountable to the goal, the team and yourself. • Passion: We are enthusiastic and dedicated to expanding scientific understanding and its impact. • Excellence: Be aggressive and have a sense of urgency but take pride in each task taken on. • Transparency: We align as an organization and communicate success and challenge. • Competitive: We do not fear but learn from making mistakes. We play to win! • Diversity: Each individual regardless of role makes a difference and impacts our progress. Additional Information We offer great perks: • Competitive salaried compensation - we value our employees and show it • Equity - we want every employee to be a stakeholder • Fully covered medical insurance plan along with a generous company sponsored health reimbursement account, and dental & vision coverage - as a health-tech company, we place great worth on our teams’ well-being • Company paid life insurance, short term and long term disability • Flexible Paid Time Off - personal responsibility for managing our own time, workload and results plus 14 paid holidays inclusive of MLK Day, Juneteenth, Indigenous People’s Day and Veterans Day • Parental Leave - we provide a generous 10 week parental leave and additional 6-8 weeks pregnancy related leave for birthing parents • Pre-tax commuter benefits - we make your commute more reasonable • Free onsite meals • 401k plan - we facilitate your retirement goals • Beautiful office near the ocean-front in historic Guilford, Connecticut OR Beautiful office in the heart of San Diego • The opportunity to build a revolutionary healthcare product and save millions of lives! The estimated base salary range for this role based in the United States of America is: $160,000 - $200,000. Compensation decisions are dependent on several factors including, but not limited to, level of the position, an individual’s skills, knowledge and abilities, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all full-time employees are eligible for our discretionary bonus program and equity as part of the compensation package. For this role, we provide visa assistance for qualified candidates. Quantum-Si does not accept agency resumes. Quantum-Si is an E-Verify and equal opportunity employer regardless of race, color, ancestry, religion, gender, national origin, sexual orientation, age, citizenship, marital status, disability or Veteran status. All your information will be kept confidential according to EEO guidelines

The Position Impact Healthcare... Roche Sequencing is not only changing science, but we are changing lives! Our team is pushing the boundary of technology with next-generation genomic sequencing. You will develop products that scientists and others in the life sciences will use to diagnose, find treatments, and eventually beat diseases like cancer. Make a Big Difference Do you want a career that enables you to make a huge difference? If so, we want you on our team! We are seeking a Principal Software Engineer to partner with bioinformatics scientists and software developers in support of building the underlying bioinformatics analysis algorithms and workflows to support Next-Generation Targeted Sequencing solutions. Own the efforts to productionize and optimize bioinformatics software working with collaborative and multi-disciplinary teams. Responsibilities: • Develop efficient, maintainable, and documented production software from scientific prototype code or specifications using software development best practices. • Define requirements for sophisticated bioinformatics software applications to develop solutions to complex algorithmic and machine learning problems; such as in the area of secondary analysis (read processing, variant calling) for next generation sequencing. • Conduct system-level analysis of software to include requirements, design, testing, modifications, planning, and performance. • Review software / algorithm specifications and code to provide feedback on potential areas of improvement. Ex. efficiently leveraging accelerated/parallel computing. • Continuously improve software development processes by implementing innovative methodologies and standards used by the Bioinformatics department for software development and testing. • Document work and provide updates at team and project meetings. • Mentor, train, and guide other developers in software standard methodologies including other bioinformaticians in the department. • Represent the project and team at various stakeholder meetings. • Conduct risk analysis and assessment of integrated software projects. Requirements: • Master’s degree in Computer Science, Computational Biology or equivalent technical field; or equivalent combination of education and experience to perform at this level. • 8+ years of experience developing software for enterprise-level customer-facing applications, including 3+ years of experience working as a BioInformatics engineer or computational biologist contributing to Next Generation Sequencing. • Expertise in programming languages such as Python and Java development. • Proficient in microservices architecture and distributed computing in a Linux environment. • Experience with various software development and support related tools such as PyTest, jUnit, Cucumber, Behave, and Command Line Tools (Linux Shell), Maven, Github. • A demonstrated skill set for developing and tuning algorithms is preferred. • Experience with workflow management tools such as Nextflow or Snakemake is preferred. • Experience with Machine learning / Deep learning (used in NGS context) is a plus. • Experience with C/C++ is a plus. • Experience developing for cloud platforms such as AWS or Google Cloud is a plus. • Experience with GPU acceleration architecture and development is a plus. • Experience developing software for diagnostics or medical devices is a plus. • Experience with Behavioral and Test Driven Development (BDD) principles is a plus. Relocation assistance is not available for this role. The expected salary range for this position based on the primary location of Pleasanton CA is $111,000-$206,100. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below. Benefits Who we are At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity. Unless entitled to a reasonable accommodation under applicable law, employees are required to be fully vaccinated against COVID-19 in accordance with customer requirements, the company’s health and safety obligations and/or applicable law or guidelines. Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual’s race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law. If you have a disability and need an accommodation in connection with the on-line application process, please email us at US.Accommodation@roche.com

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for... patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Why Us We are a multi-disciplinary and multinational team working on innovative technologies and algorithms that support genomics researchers making the discoveries that change the world. Our algorithms will be part of DRAGEN, Illumina’s software platform to analyze high-throughput sequencing data. In tight collaboration with Illumina’s R&D team, this group is focused on novel genomics applications: algorithms, bio-marker development and emerging genomics and multi-omics applications. Why You Like you, we know the importance of your role and offer you a collaborative and supportive environment in which you are actively encouraged to develop your skills and knowledge. If you want to make a difference, Illumina's mission is to improve human health by unlocking the power of the genome - if that inspires you, let's talk. If you are excited as we are about new genomics applications, are not afraid of complex equations, and have a track record of exceptional coding ability, this is the role for you. This position will inspire you to push boundaries and in a culture fueled by innovation, collaboration, and openness. If you want a brilliant, fast-paced, mission-driven environment, then Illumina is the place for you. To be successful as a Senior Manager, Bioinformatics, you will need a proven track record of accomplishments in bioinformatics with a particular focus on algorithm development, biomarkers and oncology. A consummate scientific background in at least one or all of Genomics, Statistics, Machine Learning, and/or High-Performance Computing will be key to your success. This role may be performed in our San Diego headquarters or remotely within the United States. The position requires a significant amount of work within the Pacific time zone hours. The Role The Senior Manager Bioinformatics will drive the development of innovative genomics solutions: support treatment decisions based the cancer’s molecular profile, early detection, and monitoring of malignancies. The primary function of this position will be to drive algorithm development, prototype software implementations, and execution of feasibility studies to demonstrate that our assays and algorithms meet the biomarker needs of pharma partners. The candidate will lead a team of PhD level bioinformatics scientists and will interface with cross functional teams within and outside of Illumina. Responsibilities: • Lead a team of bioinformatics scientists in innovative software and algorithm development for oncology NGS applications. • In collaboration with our experimental teams, design and analysis of experiments to support novel biomarkers using existing or new Illumina oncology assays. • Provide technical and strategic guidance to the team. • Deeply collaborate with SMEs cross-functionally within Illumina • Lead cross functional assay and algorithm R&D teams with minimal oversight. • Works closely with scientific, assay, engineering, software and commercial teams to develop, and validate new products. • Manage oncology algorithm roadmap for industry leading analysis platform. Requirements: • PhD in bioinformatics, physics, or math or related field with 4+ years of regulated industry experience in clinical algorithm development (IVD, LDT, and/or CDx). • Expert knowledge of existing bioinformatics NGS algorithms and methodology. • Proven ability to develop innovative bioinformatics algorithms. • Fluency in statistics, common bioinformatics methods, and NGS data analysis. • Ability to set technical goals for product roadmaps. • Ability to lead technical collaborations and make technical sound decisions. • Ability to think innovatively toward solving problems effectively and efficiently. • Adept interpersonal skills to contribute to cross functional project teams and work with stakeholders. • Experience with project management and good documentation practices. #LI-REMOTE #LI-HYBRID The estimated base salary range for the Senior Manager, Bioinformatics (Remote - US) role based in the United States of America is: $163,900 - $245,900. Should the level or location of the role change during the hiring process, the applicable salary range may be updated accordingly. Compensation decisions are dependent on several factors including, but not limited to, an individual’s qualifications, location where the role is to be performed, internal equity, and alignment with market data. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package. We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off. At Illumina, we strive to foster a diverse and inclusive workplace by cultivating an environment in which everyone contributes to our mission. Built on a strong foundation, Illumina has always been rooted in openness, collaboration, and seeking alternative views and perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and demonstrate our collective commitment to diversity and inclusion in the communities we live and work. We are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. If you require accommodation to complete the application or interview process, please contact accommodations@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf

Invitae (NYSE: NVTA) is a leading medical genetics company trusted by millions of patients and their providers to deliver timely genetic information using digital technology. We aim to provide accurate and actionable answers to strengthen medical decision-making for individuals and their families. Invitae's genetics experts apply a rigorous approach to data and research, serving as the foundation... of their mission to bring comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Bioinformatics Engineer/Scientist 3Remote in U.S.A Invitae is a biotechnology company passionate about providing tools and services for clinical research applications of genomics. Our mission is to unlock the power of precision medicine in improving patient care by providing a technology platform to advance genomics and facilitate collaborative research. Invitae is seeking Bioinformaticians to join our team. This role will be centered around crafting workflows, tools and algorithms to complement assay/product development. The ideal candidate should be able to perceive a problem clearly and dissect it into components which can be resolved programmatically. Having a comprehensive grasp of genomics and next generation sequencing will be key to succeeding in this role. This person should be independent, well organized and collaborative with clear communication skills. In addition, the ability to frequently switch between tasks will be helpful. As necessary, but not as a primary role, the candidate will assist the Clinical team in ad-hoc analysis and research required to meet regulatory requirements. You will be responsible for scaling our pipelines as we work toward our goal of providing low-cost genetic answers to billions of people. Responsibilities:• Develop high-performance bioinformatics workflows that can accurately and reliably analyze large volumes of Next Generation Sequencing data using Nextflow in a system agnostic manner • Collaborate in a cross-disciplinary team by building, deploying, and maintaining software solutions compatible with distributed and/or containerized systems • Designing APIs using industry best practices to streamline communication between various Invitae platforms • Develop best practices for processing of NGS data including optimization of parameters, resource utilization, and consensus approaches across various NGS applications • Drive genetics technology development in a cross-disciplinary setting by critically analyzing and deriving insights from experimental data (including NGS, arrays, and novel technologies) using open source NGS tools and building custom tools when needed • Develop reproducible analysis for research and development purposes • Review, understand, and stay in compliance with Invitae HIPAA Security policies and procedures Qualifications:• MS with 3+ years experience or PhD in Bioinformatics or Computational Biology Fluent in Python, R, • nix, and SQL like DB technology for data analysis • Working knowledge of pipeline workflow engines: Nextflow, Snakemake • Working knowledge of standard bioinformatic tools used in NGS pipelines • Strong knowledge of Genomics and Molecular Biology • Solid understanding of Illumina sequencing technologies and metrics • Formal statistics background is a plus • Formal software development experience (preferred) • Understanding of Cloud Computing (preferred) Please apply even if you don’t meet all of the “What you bring” requirements noted. It’s rare that someone checks every single item, it’s ok, we encourage you to apply anyways. Join us! We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance. We truly believe a diverse workplace is essential to our company's success and to better serve our diverse patients. Your input is especially valuable. We’d greatly appreciate it if you can take a quick moment to make your selection(s) below. Submissions will be anonymous. #LI-Remote This salary range is an estimate, and the actual salary may vary based on a wide range of factors, including your skills, qualifications, experience and location. This position is eligible for benefits including but not limited to medical, dental, vision, life insurance, disability coverage, flexible paid time off, Spring Health, Carrot Fertility, participation in a 401k with company match, ESPP, and many other additional voluntary benefits. Invitae also offers generous paid leave programs so you can spend time with your new child, recover from your own illness or care for a sick family member. USA National Pay Range $88,000—$137,500 USD Please apply even if you don’t meet all of the “What you bring” requirements noted. It’s rare that someone checks every single item, it’s ok, we encourage you to apply anyways. Join us! At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance. We truly believe a diverse workplace is crucial to our company's success and to better serve our diverse patients. Your input is especially valuable. We’d greatly appreciate it if you can take a quick moment to make your selection(s) below. Submissions will be anonymous. You can find a detailed explanation of our privacy practices here