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More Bioinformatics Jobs

Bioinformatics Scientist

Burnsville, NC
2024/05/04.

Deliverables: • Work products and documents related to applying computational data analysis approaches to make biological discoveries; identify and solve scientific or technical problems; analyze and interpret high throughput biological data; prepare and present the results to scientific peers at internal meetings as well as scientific meetings • Work products and documents related to developing... analytical approaches to integrate data generated internally; write data analysis and discussion sections of manuscripts, prepare publication quality figures; assist with additional sections of manuscripts as needed; deposit data to external or DTT-designated repositories. • Work on products and documents related to developing and maintaining custom software and pipelines; evaluate and utilize commercial and open-source software; support the design and development efforts; establish reproducible data analysis pipelines and SOPs; provide detailed documentation for methodologies. - Weekly • Meet with lab members to present updates - Weekly Work Details: • Research and review literature to retrieve targeted clinical or scientific information, including Client statistical methods, from publicly available resources. 1 • Collaborate with staff to review current and historical procedures for the acquisition, quality control, and management of data. 2 • Analyze and evaluate data cleaning and harmonization needs in the using a variety of descriptive statistics and analytic methods. 3 • Collaborate with experimentalists and computational biologists to develop new computational tools to answer research questions of interest. 4 • Identify new tools and resources for reaching biologically meaningful conclusions. 5 • Provides programming and troubleshooting support to the federal government in the dissemination of research data. • Generate and optimize programs and scripts for the analysis of data; create programs and algorithms; and develop computational infrastructure resources for organizing and parsing data from large and complex data. • Serve as bioinformatics expert and coordinate with teams of biologists to conduct experimental queries and/or perform portions of studies using complex procedures and techniques common to modern bioinformatics • Coordinate building bioinformatics infrastructure to ensure easy and meaningful scientific analysis and interpretation of data. • Provide broad-based programming and analytic support for a wide variety of bioinformatic and research projects • Install, troubleshoot, and run open-source and commercial scientific software on platforms. • Performs computations on research data analysis. • Perform computational analysis of, and interpret results. • Provide reports based on analysis of scientific data. • Perform sequencing and alignment of raw data, and interpret new data using larger public access datasets. • Provide interpretive analyses of data derived from different experimental platforms to generate biological meaning. • Write custom programs and algorithms to support data analyses and discovery. • Works with staff on scientific programming and experimental design. • Collaborate with scientists to design, analyze, manage, and interpret all types of data. • Design and execute computational experiments. • Work with staff on planning of experiments, and data analysis for internal and collaborative projects; use bioinformatics expertise to advise and help bench scientists on experimental design and troubleshooting. • Work with staff to develop specifications for new analysis; design, test and implement solutions. • Make recommendations to investigators about the correct computational tools for testing scientific hypotheses and reaching valid conclusions. • Records observations and reports results at weekly laboratory meetings. • Maintain proper and detailed documentation of the analysis performed and report results at lab meetings. • Attend scientific and programming meetings; take and compile comprehensive notes; and organize and edit content of meeting reports. • Prepare scientific reports and progress reports; assemble data to prepare tables, graphs, and slides; conduct scientific and program-related information searches and report results. • Organize daily laboratory notebook on experiments; prepare weekly updates on ongoing experiments and tasks; provide monthly progress notes on assigned projects; submit final progress reports and future directions on projects. • Organize laboratory notebook or computer database to record results of calculations. Share results at lab meetings. • Provides statistical support/analysis of research data. • Devise Client methods of statistical analysis for the collected data. • Utilize and adapt existing bioinformatics techniques to check for trends and patterns in the data. • Write complex queries to multiple databases. • Perform data processing and data analysis with existing computational and statistical methods. • Assist in evaluating and interpreting results for validity and scientific meaning. • Provides research/service goals in the context of the laboratory's overall mission. • Create Client programs and algorithms that facilitate discovery of knowledge in investigating large and complex data. • Develop and optimize programs and scripts that facilitate the organization, integration, and data-mining of large data sets; integrate these models into a framework of best practices. • Participate in the design of new protocols involving computational methods. • Work with staff on the development and maintenance of bioinformatics tools, scripts, and pipelines for data. • Participate in research design with investigators to determine best practices pertaining to the bioinformatics analysis in new and ongoing projects. • Evaluates new types of experimental approaches to protocols based on knowledge of scientific literature, available facilities and research needs. • Independently coordinates the training of personnel in the use of scientific software applications, statistical software applications and programmatic software applications. • Provide training in and technical support (including product updates and version control) for programs, algorithms, archives, and pipelines generated during the course of this work. • Instruct staff in computational analysis of data. • Provide ad hoc trainings and hands-on workshops on the use of bioinformatics tools. • Provide training of students, new investigators, and other laboratory personnel in the use of techniques, procedures and equipment to complete the objectives of the laboratory. • Onboard and train staff involved in new clinical trials, including the import of a wide variety of legacy data set; provide rigorous quality control of these data. Minimum Education: • Masters Additional Qualifications: Certifications & Licenses: • Amazon Web Services (AWS) Certification Field of Study: • Genetics • Molecular Biology • Computer Programming and Data Processing • Statistics and Decision Science Software: • SQL • R • PERL • Python • Linux Skills: • Next-Gen Sequencing Data Analysis: Bulk RNA-Sequencing • Clinical and/or Translational Research • Work with Large Data Sets • Microarray Data Analysis • Whole Genome Sequencing

Bioinformatics Programmer II

Houston, TX
2024/05/04.

We are looking for a Bioinformatics Programmer! The Bioinformatics Programmer II works with limited supervision to formulate and define project scope and objectives through investigation and fact finding to develop or modify complex information systems handling biological data. He/she uses knowledge of molecular biology and computer science to manipulate and process complex data sets. Data... management involves capturing information pertaining to biological and cellular activities captured using molecular biology methods, which may include microarray and next-generation sequencing. ESSENTIAL DUTIES AND RESPONSIBILITIES Responsibility A: Provides analysis for the design and modification of bioinformatics solutions. Analyzes and determines computerized solutions applicable for the services concerning compliance with regulatory agencies and the strategic plan or goals. Appraises effectiveness of systems flow, data usage, and manual or automated processes to identify ineffectiveness or inefficiency of the system(s)/programs(s). Develops, designs, and modifies technical specifications for bioinformatics applications. Coordinates the design and analysis of the implementation of new systems and the modifications of existing systems/programs. Works in close collaboration with TCH IS and Pathology Clinical Informatics teams for overlapping projects. Responsibility B: Provides technical expertise in the implementation and modification of bioinformatics solutions. Provides technical support in determining solutions for the services concerning compliance with regulatory agencies and the strategic plan or goals. Develops, designs, and modifies technical specifications for bioinformatics applications. Prepares detailed specifications and algorithms from which programs will be written. Investigates and assesses third-party bioinformatics software. Advises on hardware and software decisions related to efficient application of implemented software. Provides technical support in the design and analysis of the implementation of new systems and the modifications of existing systems. Act as a Change Control Lead to review and submit the reviewed change controls for final approval from appropriate leadership to move changes into production. Responsibility C: Implements and controls the configuration, development, and maintenance of bioinformatics solutions. Controls system configuration and development process by establishing standards, measuring work in process, interpreting results, and taking corrective action. Develops and administers the system configuration and development plan. Delegates tasks and responsibilities to team members according to ability, priority, etc. Performs independent programming for segments of complex problems according to the technical specifications and standard system implementation techniques. Applies existing custom bioinformatics software to both well-defined and moderately-complex problems. Designs, codes, and maintains programs and investigates software for bioinformatics applications. Analyzes system performance and optimizes programs accordingly. Provides configuration, tuning, and upgrades to systems as needed. Imports, configures, and customizes third-party bioinformatics software. Initiates and implements new programming techniques, methods, procedures, approaches, and standards. Responsibility D: Administers program and system tests. Develops and administers data verification methods and plans as needed. Tests and debugs programs and software for bioinformatics applications. Assures coded logic performs as required by testing and correcting programs via trial runs, and combines individual programs into a job stream. Performs system integration testing to ensure system integrity. Works in close collaboration with TCH IS and Pathology Clinical Informatics teams for overlapping projects. Responsibility E: Develops system documentation. Develops documentation standards and regulatory requirements. Prepares program code documentation in compliance with standards and regulatory requirements. Prepares system configuration procedures in compliance with standards and regulatory requirements. Prepares documentation concerning program and configuration issues, bugs, and resolutions in compliance with standards and regulatory requirements Responsibility F: Remains aware of any upcoming system enhancements. Works in close collaboration with TCH IS and Pathology Clinical Informatics colleagues to gain awareness of upcoming system upgrades and enhancements. Applies and conducts preliminary test on fixes and patches and reports pertinent information to the applicable leadership. Remains aware of and communicates to the Manager and Director(s) regarding upcoming system enhancements in a timely manner. Analyzes the impact, if any, on the department as well as the Hospital's operations, and reports to the applicable leadership in a timely manner of notice of enhancements as documented by the report. Provides training and education on enhancements to end-users. Responsibility G: Prepares reports. Develops "ad hoc" reports as requested ensuring quality and thoroughness in providing analysis reporting to management by established deadline, as documented by reports. Assigns access to custom report through appropriate systems utilities, as needed. Assures proper daily, weekly, and monthly distribution, as needed to maintain efficiency in providing necessary and requested information to all department area. Responsibility H: Troubleshoots and documents disruptions, providing a focal point for coordinating user and vendor support. Investigates and establishes solutions to problems arising out of daily production issues in collaboration with Medical Director(s), Assistant Director(s), TCH IS and Pathology Clinical Informatics colleagues. Coordinates issue resolution with the team. Works in close collaboration with TCH IS and Pathology Clinical Informatics teams for resolution of overlapping issues. Provide technical guidance and work direction to lower-level bioinformatics and information systems personnel. Knowledge and Skills Experience with Python, databases and SQL Familiarity with the development cycle: build, debug, test, deploy, validate, document, maintain production-level software Familiarity with version control systems, continuous integration processes, reproducibility, data analysis and manipulation of data sets Working knowledge of object-oriented Python and familiarity with packages like biopython, pandas, numpy, scikit-learn and django Familiarity with web interfaces, bioinformatics databases, Illumina based NGS methods and tools Familiarity with variant detection in oncology Familiarity with other languages, e.g. R, C++, VBA Knowledge of current laboratory practices and computing systems, interfaces, and current standard software. Project management and planning, leadership skills, excellent written and verbal communication, analytical, and organizational skills, ability to analyze the functionality of systems and their fit with specifications, and the ability to work independently with minimum supervision. Key skills are observation, results oriented, and communication. QUALIFICATIONS Education - Bachelor's Degree Biological science, Computer science, Computational/programming, or related technical area required - Prefer master's degree Biological Science, Computational/Programming, Computer science, or related field Experience - 2 years Relevant bioinformatics experience in a clinical setting Since 1954, Texas Children's has been leading the charge in patient care, education and research to accelerate health care for children and women around the world. When you love what you do, it truly shows in the smiles of our patient families, employees and our numerous accolades such as being consistently ranked as the best children's hospital in Texas, and among the top in the nation by U.S.News & World Report as well as recognition from Houston Business Journal as one of this city's Best Places to Work for ten consecutive years. Texas Children's comprehensive health care network includes our primary hospital in the Texas Medical Center with expertise in over 40 pediatric subspecialties; the Jan and Dan Duncan Neurological Research Institute (NRI); the Feigin Center for pediatric research; Texas Children's Pavilion for Women, a comprehensive obstetrics/gynecology facility focusing on high-risk births; Texas Children's Hospital West Campus, a community hospital in suburban West Houston; and Texas Children's Hospital The Woodlands, the first hospital devoted to children's care for communities north of Houston. We have also created the nation's first HMO for children, established the largest pediatric primary care network in the country and a global health program that is channeling care to children and women all over the world. Texas Children's Hospital is also academically affiliated with Baylor College of Medicine, one of the largest, most diverse and successful pediatric programs in the nation. To join our community of 14,000+ dedicated team members, visit texaschildrenspeople.org for career opportunities. You can also learn more about our amazing culture at infinitepassion.org. Texas Children's is proud to be an equal opportunity employer. All applicants and employees are considered and evaluated for positions at Texas Children's without regard to mental or physical disability, race, color, religion, gender, national origin, age, genetic information, military or veteran status, sexual orientation, gender identity, marital status or any other protected Federal, State/Province or Local status unrelated to the performance of the work involved

Bioinformatic Scientist

Hazelwood, MO
2024/05/04.

Description Come and join a family-owned global company with a long-term vision, and a human-centered culture.We are searching for a bioinformatics scientist to join the Sequencing team in the R&D Microbiology department. This opportunity offers the chance to work in a fast-paced environment with a dedicated and collaborative team. The Bioinformatics Scientist is responsible for designing... improving, modifying, and operating data analysis pipelines. Provide bioinformatics support to R&D. Description Responsibilities Develops and implements tools and reference databases for genomic analysis of eukaryotic pathogens Analyzenext-generationsequencing (NGS)datasuch asWGS and targeted sequencingand othermicrobiome data Construct NGS libraries for the assigned pipeline, which may be whole genomeor amplicon andoperation of related sequencing platform Generate high-quality reports forsequencing requestsdocumentation, communicate with team members effectively, and good time management. Interface with data scientists from across the company to leverage and develop new state of the art machine learning tools, data analysis capabilities, and informatic systems. Trainingotherstaff on the use of relevant bioinformatics software and tools. Collaborative attitude for department and inter-departmental activities both within the US and internationally Qualifications/ Requirements Bachelors Degree in Bioinformatics, Computer Science, Statistics, orarelated field with at least 5 yearsofwork experience in sequencing data analysis. Masters Degree in Bioinformatics, Computer Science, Statistics, orarelated field with at least 2 yearsofwork experience in sequencing data analysis. Knowledge of prokaryotic and eukaryotic molecular biology and microbiology. Solid computational skills and a deep understanding of NGS data and its analysisarerequired. Experience with bioinformatics tools (Blast,Resfinder, CLC workbench, Galaxy)arerequired. Codingskillsin at least one language (Perl, Python, R, etc.). Proficiency in Unix/Linux environment, including proficiency inshell scripting. Contribute tojournal publications and presentationsat professional meetings. Critical and Analytical thinking Skill to manage multiple projects simultaneously. Excellent communication and interpersonal skills

Principal/Lead Bioinformatics Research Scientist

Memphis, TN
2024/05/04.

The Principal/Lead Bioinformatics Research Scientist functions independently to coordinate large-scale bioinformatics projects, providing project oversight, scientific and technical advice, programming support, and other input as required to achieve established objectives. Coordinates the specialized expertise of bioinformatics colleagues to achieve scientific objectives. Establishes best... practice recommendations, creates educational materials, and participates in educational initiatives at the laboratory, departmental, and/or institutional level. The new Department of Host-Microbe Interactions is seeking a talented and highly motivated Principal Bioinformatics Research Scientist or Lead Bioinformatics Research Scientist with extensive experience in large-scale microbial genomic data analysis to create and direct the new Microbial Computational Genomics and Bioinformatics Laboratory at St. Jude Children’s Research Hospital. The Microbial Computational Genomics and Bioinformatics Laboratory's mission is to support initiatives on microbial genomic, phylogenomic, and computational needs of researchers in the Department of Host-Microbe Interactions and the Center for Infectious Disease Research. The laboratory is a major initiative backed by substantial support as a part of our institutional strategic plan and will be fully integrated with research in microbial evolution, microbial pathogenesis, virology, the microbiome, computational biology, and data sciences at St. Jude Children’s Research Hospital. The focus of this position is on bacterial and viral genomics, using specimens and data obtained from our healthcare system to address key questions such as the acquisition of antimicrobial resistance, genome heterogeneity, outbreaks, transmission, and the identification of potential targets for the generation of novel therapies. This will be achieved using a combination of approaches, including: short-and long-read whole genome sequencing; phylogenomic, transcriptomic, and bioinformatics approaches involving electronic health data; and experimental data generated by collaborating partners. Data analysis will focus on answering clinical questions, generating insights to prevent infections, and building predictive models of disease susceptibility. The successful candidate will assemble a team of Ph.D.- and MS-level bioinformaticians and data scientists to analyze and interpret newly generated as well as existing large collections of microbial whole-genome sequences and metagenomes, using cutting-edge bioinformatics approaches to address project aims. The director will present research findings at project meetings, scientific conferences, and outreach/training events. There will be opportunities to initiate new projects and collaborate with other groups at St. Jude, including clinicians, basic scientists, and data scientists. The ideal candidate should have: • A PhD and extensive postdoctoral experience in microbial genomics, phylogenomics, bioinformatics, computational biology, and data science. • A strong CV that includes high-profile publications in the field of computational biology and microbial genomics. • Extensive expertise in analyzing, interpreting, and visualizing microbial genomics and microbiome datasets generated by high throughput sequencing technologies including short- (Illumina) and long-read- (e.g. PacBio and Oxford Nanopore) whole genome sequencing. • Extensive experience performing statistical analyses of large microbial genomic datasets and validation of genomic pipelines. • Expert-level proficiency in relevant programming languages such as R and Python, preferably in a High-Performance Computing (HPC) environment. • Preferably, proficiency in tools for ensuring reproducibility of pipelines, such as workflow management systems (e.g., nextflow or snakemake), and version control (e.g., git). • Preferably, experience with database management systems such as MySQL. • Extensive expertise in data integration and harmonization. • Possess a deep understanding of essential bioinformatics concepts and algorithms, e.g., alignment, SNP nucleotide calling, classification of nucleotide and protein sequence, phylogenetics, and genomic assembly. • Previous experience working in the field of infectious diseases is preferred. • Proven problem-solving skills and collaborative nature in fast-paced environment. • Excellent communication and presentation skills. Responsibilities: • Develop and apply state-of-the-art computational approaches to characterize and assemble microbial genomes and metagenomes. • Attract, recruit, and supervise staff to create a strong team for the operation of the Microbial Computational Genomics and Bioinformatics Laboratory. • Collaborate with the St. Jude Children’s Research Hospital data science initiative to develop computational pipelines for handling large, complex genomic datasets requiring custom approaches to accommodate project-specific analytical requirements. • Interface and collaborate with the IT department to develop and maintain capabilities for analysis, interpretation, and storage of the genomic data. • Maintain a high level of professional expertise through familiarity with scientific literature and scientific networking. • Create and implement educational and outreach programs to enhance microbial genomics capabilities and usage within the St. Jude Children’s Research Hospital community. • Train MS and PhD level graduate students in microbial computational genomics. • Collaborate and enable external funding applications. Minimum Education: • Bachelor's degree in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry) or related field. • Master's degree or PhD preferred. Principal Bioinformatic Research Scientist Minimum Experience: • Minimum Requirement: Bachelor's degree with 13+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 11+ years of relevant post-degree experience (OR) PhD with 8+ years of relevant post-degree experience. • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Lead Bioinformatic Research Scientist Minimum Experience: • Minimum Requirement: Bachelor's degree with 10+ years of relevant post-degree work in bioinformatics, cheminformatics, statistics/computer science (with a background in biological sciences or chemistry). • Experience Exception: Master's degree with 8+ years of relevant post-degree experience (OR) PhD with 5+ years of relevant post-degree experience. • Substantial experience in at least one programming or scripting language and at least one statistical package, with R preferred. Compensation In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $138,320 - $262,080 per year for the role of Principal/Lead Bioinformatics Research Scientist. Explore our exceptional benefits! Diversity, Equity and Inclusion St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment. Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future. St. Jude is an Equal Opportunity Employer No Search Firms St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude

Bioinformatics Programmer- Hybrid/Remote - 128709

California
2024/05/04.

Payroll Title: BIOINFORMATICS PROGR 2 Department: PEDIATRICS Hiring Pay Scale... $35.58 - $50.00 / Hour Worksite: Campus Appointment Type: Career Appointment Percent: 100% Union: Uncovered Total Openings: 2 Work Schedule: Days, 8 hour shifts, Monday - Friday #128709 Bioinformatics Programmer- Hybrid/Remote Filing Deadline: Wed 5/8/2024 Apply Now UC San Diego values equity, diversity, and inclusion. If you are interested in being part of our team, possess the needed licensure and certifications, and feel that you have most of the qualifications and/or transferable skills for a job opening, we strongly encourage you to apply. UCSD Layoff from Career Appointment: Apply by 3/15/2024 for consideration with preference for rehire. All layoff applicants should contact their Employment Advisor. Special Selection Applicants: Apply by 3/27/2024. Eligible Special Selection clients should contact their Disability Counselor for assistance. This position will work a hybrid schedule which includes a combination of working both onsite on Campus and remote. DESCRIPTION The Department of Pediatrics is one of the largest departments within the School of Medicine with approximately 250 Faculty, 127 postdoctoral fellows (both MDs and PhDs) along with over 320 support staff (not including hospital staff). In addition, the Department has 68 clinical residents distributed across the Divisions. The missions of research, education and patient care are intertwined, and are integral to the goals of the department. The Department manages a university-affiliated children's health system with the physicians and leadership of the University of California, San Diego (UCSD), Rady Children's Hospital, and Rady Children's Specialists of San Diego, a Medical Practice Foundation, unifying pediatric patient care, research, education and community service programs. Under supervision, the Bioinformatics Programmer supports the development of two NIH-funded platforms, PanKBase and Common Fund Knowledge Center, both of which involve the collection and processing of genomic and other experimental data, recording detailed meta-data, establishing reproducible data processing pipelines and quality control standards, developing databases, web interfaces, APIs and other tools, and working collaboratively with other groups involved in these projects The incumbent uses professional bioinformatics concepts. Applies computational procedures to resolve a variety of analysis and research issues. Works on assignments of moderate scope where analysis of data requires a review of a variety of factors. Assists in additional analyses as needed to achieve research objectives. MINIMUM QUALIFICATIONS • Six (6) years of related experience, education/training, OR a Bachelor's degree in related area plus two (2) years of related experience/training. • Working knowledge of bioinformatics methods and data structures. • Working knowledge of applications programming and web development. • Working knowledge of databases. • Working project management skills. • Working knowledge of modern biology and applicable field of research. • Interpersonal skills in order to work with both technical and non-technical personnel at various levels in the organization. • Ability to communicate technical information in a clear and concise manner. • Self motivated, able to learn quickly, meet deadlines and demonstrate problem solving skills. • Working knowledge of application and data security concepts. • Experience with programming in Python and R, bioinformatics pipeline development, experience working with high-throughput experimental data, experience with cloud platforms such as AWS, ideally web development and web visualization development. SPECIAL CONDITIONS • Employment is subject to a criminal background check. Pay Transparency Act Annual Full Pay Range: $74,300 - $134,500 (will be prorated if the appointment percentage is less than 100%) Hourly Equivalent: $35.58 - $64.42 Factors in determining the appropriate compensation for a role include experience, skills, knowledge, abilities, education, licensure and certifications, and other business and organizational needs. The Hiring Pay Scale referenced in the job posting is the budgeted salary or hourly range that the University reasonably expects to pay for this position. The Annual Full Pay Range may be broader than what the University anticipates to pay for this position, based on internal equity, budget, and collective bargaining agreements (when applicable). Apply Now If employed by the University of California, you will be required to comply with our Policy on Vaccination Programs, which may be amended or revised from time to time. Federal, state, or local public health directives may impose additional requirements. If applicable, life-support certifications (BLS, NRP, ACLS, etc.) must include hands-on practice and in-person skills assessment; online-only certification is not acceptable. UC San Diego Health Sciences is comprised of our School of Medicine, Skaggs School of Pharmacy and Pharmaceutical Sciences, The Herbert Wertheim School of Public Health and Human Longevity Science, and our Student Health and Well-Being Department. We have long been at the forefront of translational - or "bench-to-bedside" - research, transforming patient care through discovery and innovation leading to new drugs and technologies. Translational research is carried out every day in the hundreds of clinical trials of promising new therapies offered through UC San Diego Health, and in the drive of our researchers and clinician-scientists who are committed to having a significant impact on patient care. We invite you to join our team! Applications/Resumes are accepted for current job openings only. For full consideration on any job, applications must be received prior to the initial closing date. If a job has an extended deadline, applications/resumes will be considered during the extension period; however, a job may be filled before the extended date is reached. To foster the best possible working and learning environment, UC San Diego strives to cultivate a rich and diverse environment, inclusive and supportive of all students, faculty, staff and visitors. For more information, please visit UC San Diego Principles of Community. UC San Diego is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the University of California’s Affirmative Action Policy please visit: https://policy.ucop.edu/doc/4010393/PPSM-20 For the University of California’s Anti-Discrimination Policy, please visit: https://policy.ucop.edu/doc/1001004/Anti-Discrimination UC San Diego is a smoke and tobacco free environment. Please visit smokefree.ucsd.edu for more information. UC San Diego Health maintains a marijuana and drug free environment. Employees may be subject to drug screening

Bioinformatics Engineer

Indianapolis, IN
2024/05/04.

The Diabetes, Obesity and Complications Therapeutic Area (DOCTA) of Eli Lilly and Company, focuses on the discovery of biologic, small molecule and genetic therapeutics for the treatment of diabetes, obesity and associated complications. The successful candidate will be responsible for supporting the data, tools and infrastructure that are critical for enabling clinical research objectives that... will inform and accelerate the discovery and development of our next generation obesity therapeutics. Specifically, we are seeking a key multi-dimensional individual to integrate and analyze genomic, proteomic, metabolomic and phenotypic data from clinical trials on cloud based clinical multi-omics platforms. Are you interested in working on groundbreaking science? Apply today to join the Lilly Team! You will operate as part of a team of DOCTA early discovery scientists and clinicians, translational scientists, bioinformaticians and geneticists to: • Steward a secure and scalable cloud platform that enables clinical omics collaboration and is tailored to internal and external project needs • Develop, orchestrate, and maintain primary, secondary, and tertiary NGS analytical pipelines • Ingest and integrate large scale omics (genomics, proteomics, etc.) and phenotypic data and surface the data to scientists within DOCTA • Engage and collaborate with other scientists to develop and maintain workflows needed to process and analyze multi-modal data • Function independently within dynamic team-oriented environments and within cross-functional project teams as part of a multi-dimensional role Minimum qualifications: • Bachelors Degree in bioinformatics, computational biology, data science, data engineering, or other applied science with 5+ years of relevant work experience • Masters Degree in bioinformatics, computational biology, data science, data engineering, or other applied science with 3+ years of relevant work experience Additional Skills/Preferences • Experience implementing and deploying bioinformatics pipelines using software and data architectural standard processes in a distributed/cloud environment • Proven experience with AI/ML model development and/or bioinformatic applications through publication in a peer reviewed journal • Expertise in systems biology, bioinformatics, and genomics • Demonstrated communication (oral and written) skills and ability to work collaboratively in a team-oriented environment • Extensive experience in solving scientific problems using programming languages relevant to data analysis such as Python, R, Bash (shell scripting), etc. • Strong problem-solving skills and proven ability to troubleshoot issues

Reserach Intern - Bioinformatics and Computational Biology

Houston, TX
2024/05/04.

The research intern will be training and collaborating with Dr. Su's Lab within the Department of Bioinformatics and Computational Biology. The research intern will be exposed to a variety of projects that are conducted in Dr. Su's Lab, ranging from projects on performing alignment for NGS data such as RNA-Seq, DNA-Seq, ChIP-Seq, and ATAC-Seq data; implementation of R scripts to perform... clustering analysis for scRNA-Seq data; or writing scientific manuscripts for publications. LEARNING OBJECTIVES Learn how to use high-performance computing cluster for bioinformatics data analysis. Specifically, write HPC job submission scripts for different bioinformatics data analyses, and perform alignment for NGS data such as RNA-Seq, DNA-Seq, ChIP-Seq, and ATAC-Seq data by using HPC cluster. Implement R scripts to perform clustering analysis for scRNA-Seq data. Improve scientific writing skills. Improve verbal communication skills. ELIGIBILITY REQUIREMENTS Bachelor degree in Computer or related field. ADDITIONAL APPLICATION INFORMATION This is an unpaid research opportunity

BioInformatics Scientist

College Station, TX
2024/05/04.

Advanta is a global seed business adapting to rapidly increasing food insecurity and climate change by providing farmers with innovation and new technologies. As part of UPL Group, Advanta aims to deliver high quality seeds with excellent agronomic practices and crop protection solutions. Advanta operates in over 80 countries under global brands of Advanta, Alta and Pacific Seeds. Advanta holds a... leadership position in tropical and sub-tropical geographies in corn, grain and forage sorghum, sunflower, canola, rice, and a variety of vegetables. With over 60 years' experience in plant genetics, Advanta provides seeds technology that ensures crop performance and farmers prosperity. Job Responsibilities: • Manage and maintain all genomic databases. • Assemble and maintain pangenome data for field crops. • Develop and maintain a data imputation pipeline. • Implement, manage, and maintain a BLAST server and a genome browser. • Support other areas with Bioinformatics data mining and analysis of NGS data. Required and Desired Skills: • A PhD. degree in Bioinformatics, Computational Biology or related fields. • Coding knowledge in R, Python and SQL. • Experience in Linux environments. • Basic knowledge of genomics. • Knowledge of cloud computing preferred. • Proactive, self-motivated and self-driven person with high accountability. • Team player with excellent interpersonal and communication skills COMPETENCIES: • Adaptability & Resilience: Recognizes and is open to changing circumstances and alters behavior and scales up as necessary; increases personal awareness and appreciation of individual and cultural differences to create an open, inclusive, and accepting workplace. • Entrepreneurial Mindset: Has a creative mindset and ability to think holistically, takes calculated risks and maximizes opportunities. • Results Orientations: Takes action, pursues goals with persistence and achieves results; communicates goals and vision to the team to drive enthusiasm and ambition. • Execution Excellence: Enhances the speed of execution and builds efficiency in processes, systems and people; has sharp focus on quality-orientation. • Strategic Orientation: Demonstrates knowledge of the social, economic, and environmental factors and how they impact the business. Identifies key issues that could impact the business and develops strategy through an analytical lens / design thinking. • Building Teams and Talent: Empowers colleagues through knowledge sharing and delegation, quickly establishing rapport; provides recognition for achievements and accomplishments. • Customer Centricity: Understands the customer needs and pain points, fulfills the needs and expectations by focusing on creating value for customers. We are one team, for maximum impact. One team with shared goals. We all play for the team and no one plays against the team. We have a laser-like focus on what our customers need and want, on anticipating their future needs and on how we can create innovative solutions and experiences for them. #AdvantaJobs

Associate Data Scientist Bioinformatics

Houston, TX
2024/05/04.

The primary purpose of the Associate Data Scientist is to leverage the capabilities of next-generation sequencing data to drive forward the discovery and development of novel therapeutics for cancer patients. This crucial role is centered on analyzing and interpreting intricate genetic information at the single-cell level to identify unique biomarkers and understand tumor heterogeneity. By... crafting advanced computational tools and algorithms, the Associate Data Scientist will play a crucial part in accelerating scientific discoveries and contributing to the development of new therapies and diagnostics that can transform patient care and health outcomes. Led by Prof. Bissan Al-Lazikani, Director of Therapeutics Data Science, the intelligent and ever-learning A3D3a platform is part of the new initiative in Therapeutics Data Science and part of our ambitious Institute for Data Science in Oncology at MD Anderson. A3D3a will accelerate the discovery and impact of novel therapies for cancer by enabling novel opportunities for optimized therapies for patients with a focus on rare and hard-to-treat cancers through the development of novel machine learning and AI technologies. JOB SPECIFIC COMPETENCIES • Carry out preparation, clean-up, and quality control of biological data, including scRNA-Seq, scATAC-Seq, Spatial transcriptomics and/or other multi-dimensional omic data modalities, • Develop and maintain pipelines for bioinformatics and statistical analyses of aforementioned data types; activities to include handling raw data, evaluating outputs, optimizing parameters and summarizing findings. • Collaborate with interdisciplinary teams to design experiments and analyze data from various single cell platforms. • Maintain knowledge of latest bioinformatic approaches and variety sequencing technologies, especially in single-cell context. • Present results at multidisciplinary project meetings. • Produce output for scientific publications and co-author said publications. • Prepare written reports, manuscripts, and grant applications with investigators. • Work closely with the team and collaborators to discover novel therapeutic opportunities for cancer patients. Expected Skills • Deep knowledge of bioinformatics tools and their implementation as part of pipelines, particularly for scRNA-Seq, scATAC-Seq, Spatial transcriptomics and/or other multi-dimensional omic data modalities. • Demonstrated experience and understanding of genomic technologies and analysis of data generated. • Analyzing and interpreting outputs to identify insights and hypotheses from data. • Understanding of essential statistical methodologies required for bioinformatics analyses. • Addressing challenges in bioinformatics as well as mitigation strategies such as bias, batch correction, etc. • Utilizing High Performance Computing to run large-scale analyses. • Unix, R, Python or other scripting/programming languages. • Other duties as assigned. COMPETENCIES • With Inclusion, you understand that your ideas and contributions are valued. You promote the same for others. You address your own biases while promoting diversity and equity. (Competencies: Cultural Humility, Cultural Awareness, Cultural Intelligence) • With Drive, you see that you can serve as a leader whether you have a formal leadership role or not. You tackle problems, move past setbacks and hardships, and don't lose sight of your goals. (Competencies: Self-Confidence, Analytical Thinking, Innovative Thinking, Technical Expertise) • You demonstrate Professionalism by setting the example for others and consistently modeling MD Anderson's values and service standards. You communicate effectively in a variety of ways. (Competencies: Inspire Trust, Oral Communication, Written Communication) • Through Emotional Intelligence, you maintain awareness of your own emotions and the emotions of those around you. Use nonverbal cues and feelings to engage others in an inclusive and responsive way. (Competencies: Active Listening, Teaming, Self-Reflection) • Having Coachability means you are engaged in relentless learning. You constantly ask questions and stay curious. You understand that the organization constantly evolves, and you should as well. (Competencies: Develop Oneself, Adaptability) Working Conditions Laboratory environment This position requires: Working in Office Environment ____No __X_ Yes Working in Patient Care Unit (e.g., Nursing unit; outpatient clinic) _X_ No ____ Yes Exposure to human/animal blood, body fluids, or tissues __X__No __ Yes Exposure to harmful chemicals __X__No ___ Yes Exposure to radiation _X_ No ____ Yes Physical Demands Indicate the time required to do each of the following physical demands: Time Spent Never 0% Occasionally 1-33% Frequently 34-66% Continuously 67-100% Standing X Walking X Sitting X Reaching X Lifting/Carrying Up to 10 lbs. X 10lbs to 50 lbs. X More than 50 lbs. X Pushing/Pulling Up to 10 lbs. X 10lbs to 50 lbs. X More than 50 lbs. X Use computer/keyboard X EDUCATION: Required: Bachelor's degree in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field. Preferred: PhD in Biomedical Engineering, Electrical Engineering, Computer Engineering, Physics, Applied Mathematics, Statistics, Computer Science, Computational Biology, or related field. EXPERIENCE: Required: Two years experience in scientific software development/analysis. Preferred: Experience with single cell sequencing analysis. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html Additional Information • Requisition ID: 166297 • Employment Status: Full-Time • Employee Status: Regular • Work Week: Days • Minimum Salary: US Dollar (USD) 85,000 • Midpoint Salary: US Dollar (USD) 106,500 • Maximum Salary : US Dollar (USD) 128,000 • FLSA: exempt and not eligible for overtime pay • Fund Type: Soft • Work Location: Hybrid Onsite/Remote • Pivotal Position: Yes • Referral Bonus Available?: Yes • Relocation Assistance Available?: Yes • Science Jobs: Yes #LI-Hybrid

Computational Biologist I, Bioinformatics

Dallas, TX
2024/05/04.

Why UT Southwestern? With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. At UT Southwestern, we invest in you with opportunities for career growth and development that align with your future goals and help to provide security for you and your family. Our highly competitive benefits package offers... healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more that are all available on the day you start work. UT Southwestern is honored to be a veteran-friendly work environment that is home to approximately 800 veterans. We value your integrity, dedication, and the commitment you've made to our country. We're proud to support your next mission. Ranked by Forbes as one of the Top 10 National Employers, we invite you to be a part of the UT Southwestern team where you'll discover teamwork, professionalism, and consistent opportunities for growth. Job Summary Join UT Southwestern as a Computational Biologist I in the Bioinformatics department. This position will perform professional work in support of scientific research using technical knowledge of software, software development, networking, and/or hardware in a complex computing environment. Manage research laboratory computer hardware and software programming and maintenance. Ensure existing systems meet the continuing needs of the lab and/or recommend and test new systems as necessary. Perform complex data analysis related to specialized research methodologies and results as assigned by the Principle Investigator. Develop and/or modify software to support new and ongoing research projects. Resolve hardware, software, and network issues in support of the laboratory. Develop and maintain complex databases to support new and ongoing research projects. Train laboratory staff in the use of pertinent research systems. May specialize in bioinformatics, software development, network administration, or hardware/software maintenance. A successful candidate for this position will be a part of the DSSR (Data Science Shared Resource) team as a spatial omics data analysis expert. The DSSR is designated to provide high-quality, comprehensive bioinformatics and data analytics services to members of Simmons Comprehensive Cancer Center at UT Southwestern Medical Center. Please find more information about the DSSR at Data Science Shared Resource | UT Southwestern, Dallas, Texas Required Experience and Education Master's degree in Computer Science or a related field of biological science. Bachelor's degree in Computer Science or a related field of biological science, and two (2) years related research experience in bioinformatics and computational biology. Preferred: Experience in Spatial Omics data analysis as well as in various NGS data analyses. M.S. or Ph.D. degree in Bioinformatics, Computer Science, Biotechnology, or similar; Fluency in relevant programming languages such as R, Python, MATLAB, etc.; Work experience with Linux. Job Duties • Manage research laboratory computer hardware and software programming and maintenance. Ensure existing systems meet the continuing needs of the lab and/or recommend and test new systems as necessary. • Perform complex data analysis related to specialized research methodologies and results as assigned by the PI. • Develop and/or modify software to support new and ongoing research projects. • Resolve hardware, software, and network issues in support of the lab. • Develop and maintain complex databases to support new and ongoing research projects. • Train laboratory staff in the use of pertinent research systems. • May specialize in bioinformatics, software development, network administration, or hardware/software maintenance. • Perform other duties as assigned. This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information. UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status. To learn more, please visit: https://jobs.utsouthwestern.edu/why-work-here/diversity-inclusion

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