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More Bioinformatics Jobs

Bioinformatics Engineer, Pipeline

Anywhere
2021/12/18.

Invitae is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people. Our team is driven to make a difference for the patients we serve. We are leading the transformation of the genetics industry, by making genetic testing affordable and accessible for everyone to guide health decisions across all stages of life. Our development... team works on a variety of projects ranging from innovations in healthcare systems to taming the chaos of biology. We are constantly improving our tools and technologies to deliver the highest quality actionable information to doctors and patients. Behind every sample that comes in through the door we know there is an individual and a family looking for answers. What You’ll Do • Maintaining, improving, and adding to our catalog of production bioinformatics pipelines across an expanding set of modern assays • Scaling our pipelines • Collaborate closely with bioinformaticians, molecular biologists, and software engineers What You Bring • Strong experience in bioinformatics and pipeline efforts • Passion about writing clean, reusable, and composable bioinformatics pipelines • Capability to lead technical efforts • Strong experience analyzing data from a range of genetics technologies (especially Illumina and PacBio sequencing and arrays) • Passion to contribute to source code for large open source projects with Python knowledge required • Excellent communication (written and verbal) and data presentation skills • Preferred: Experience with High-Performance Computing (HPC) environments (e.g. S/UGE, LSF, and/or Amazon AWS) • Preferred: Experience with Distributed Workflow managers, e.g. airflow, luigi, COSMOS • Preferred: Experience using and designing RESTful and RPC-style interfaces • Preferred: Experience with Docker or other containerization/virtualization • Preferred: Experience with CI/CD At Invitae, you’ll work alongside some of the world’s experts in genetics and healthcare at the forefront of genetic medicine. Our teams thrive in our dynamic organization, which has been designed to empower them to make the biggest impact they can for our patients. We give our employees the ability to explore interests and capabilities broadly within the organization. We prize freedom with accountability and offer significant flexibility. We also provide excellent benefits and competitive compensation in a fast-growing organization. At Invitae, we’re changing healthcare to change lives. Join us. At Invitae, we value diversity and provide equal employment opportunities (EEO) to all employees and applicants without regard to race, color, religion, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of the San Francisco Fair Chance Ordinance

Bioinformatics Analyst

New York, NY
2021/12/18.

Position Summary Performs computational analysis of genomic data; writes computer code and scripts to implement analytical pipelines... • *Job Responsibilities** + Performs custom bioinformatics and statistical analyses involving genomic and transcriptomics data. + Assists with developing new software tools and writes code for specific analyses. + Implements analytics pipeline using scripting and coding. + Performs other related duties as assigned. • *Education** + Bachelor's Degree in related field • *Experience** B.S. in molecular biology, genetics, bioinformatics, biomedical engineering or computer science desired. MS or PhD in systems biology, bioinformatics or computer biology is highly desired. Approximately 2 years of related experience. Knowledge proficiency in Unix. Programming experience in at least one of the following languages: R C, C++, Python, Perl, Java. Experience in biology and/or cancer biology is preferred. Experience working in an academic environment is highly desired. Previous experience in designing and building bioinformatics workflows preferred. Previous experience analyzing and summarizing genomic datasets preferred. • *Knowledge, Skills and Abilities** + Experience with R and Python programming, statistical analyses and use of next generation sequencing tools such as STAR, TopHat, CuffLinks, BWA, GATK and others. + Ability to work with minimal supervision, and excellent written and oral communication skills, required. + Demonstrated ability to achieve results in a fast paced, deadline driven environment with multiple priorities and multiple stakeholders. + Experience with genomics and bioinformatics in a clinical laboratory including setting up, testing and maintaining bioinformatics workflows + Ability to learn and deliver work in fast-paced and diverse environment • *Licenses and Certifications** • *Working Conditions/Physical Demands** Weill Cornell Medicine is a comprehensive academic medical center that's committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world. Our doctors and scientists-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization-are engaged in world-class clinical care and cutting-edge research that connect patients to the latest treatment innovations and prevention strategies. Located in the heart of the Upper East Side's scientific corridor, Weill Cornell Medicine's powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U.S. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria and Turkey. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, NewYork-Presbyterian/Lower Manhattan Hospital, and NewYork-Presbyterian/Queens. At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients - the center of everything we do. Weill Cornell Medicine is an Equal Employment Opportunity Employer. Weill Cornell Medicine provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information

Bioinformatics Engineer

New York, NY
2021/12/18.

• Viome Life Sciences aims to digitize, decode and decipher human biology to prevent and reverse chronic diseases, cancer, and aging. • We apply systems biology and advanced microbiology to deeply understand the origin and progression of disease using gene expression (mRNA) analysis with a state-of-the-art AI and machine learning platform. • Viome’s tests and clinical studies measure host/microbe gene expression, using which we discover disease biomarkers. • Our consumer business uses these data analyses, and with insights from modern medical science our AI recommends a nutrition and lifestyle plan personalized for you. • Our health science business also uses the biomarkers to develop predictive, diagnostic, and therapeutic solutions for a range of diseases, especially cancer, metabolic, and neurological diseases. • Viome’s rich data sources are unmatched in their depth and ability to provide insights. • Our small interdisciplinary team is passionate about transforming the life... science industry for the 21st century. • We are seeking a Bioinformatics Engineer with deep expertise in computational analyses of the microbiome. • Working in conjunction with a multi-disciplinary R&D team, you will work on the analysis of meta-transcriptomics, meta-genomics, and multi-omics data sets with a world-class team and platform from which we will discover, validate and develop cutting-edge next generation products. • This is a unique opportunity to have an impact on the success of a well-positioned, well-financed biotechnology company. • This is a full-time position at our office in New York, NY. The specific title and role will be determined based on the candidate’s background and experience. • Viome is a 150+ person start-up offering a successful commercial product that has generated high demand and is building out a vision to offer FDapproved diagnostics and therapeutics to patients. • With offices in Washington and New York, we are looking to hire team members capable of working in dynamic environments, who have a positive attitude and enjoy collaboration. • If you have the skills and are excited about Viome’s mission, we’d love to hear from you. • Viome does not discriminate on the basis of race, color, gender, disability, veteran, military status, religion, age, creed, national origin, sexual identity or expression, sexual orientation, marital status, genetic information, or any other basis prohibited by local, state, or federal law

Bioinformatics Scientist

New York, NY
2021/12/18.

Global Financial Firm has an immediate long term contract opportunity for an experienced Basic 5 Specialist Remote- must work in EST time zone... Business skills • Desirable: Knowledge in banking products (DDA accounts, Loans & Deposits, Accounting, Payments) Tech Skills-Required: Sr "Basic pro" Programming language – • Required: Sr in software engineering activities and SDLC-Required: Agile Methodology-Desirable: Shell scripting – Red hat Linux Language Skills-Preferred: Spanish and English in intermediary degree of reading, writing and conversation. Soft Skills-Solid analytic and creative capacity • High selforganizing and selfdriven • High adaptability to work on concurrent demands • Responsible, teamwork spirit, goaldriven Job Requirements: Basic 5

Computational Biologist

New York, NY
2021/12/18.

Deerfield Discovery and Development, LLC (3DC) engages in drug discovery research in collaboration with premier universities and biopharmaceutical companies across the United States. 3DC is the drug discovery arm of Deerfield Management Company, L.P. (“Deerfield”), an investment firm dedicated to advancing healthcare. The goal of 3DC is to enable portfolio companies of Deerfield’s investment... funds to create a pipeline of medically important and commercially viable projects at a scale sufficient to produce value for patients and investors. Project teams consist of scientists from a wide variety of disciplines (chemistry, biology, DMPK, toxicology, computational science, software and automation engineering), working together in a highly collaborative environment to advance these goals. We are seeking a Computational Biologist to work with Matt Nelson, Vice President of Genetics and Genomics, to help develop novel insights into the role that genes play in disease and apply them to novel target discovery, target validation, portfolio prioritization, and to support private and public investment activities. This position is open to all levels of experience for candidates with a minimum of three years conducting bioinformatics research in the context of drug discovery and development. • Take a leading role in the integration of insights from genetic and genomic data to support the identification of new drug targets, the review of proposed targets, the ongoing validation of existing targets, and identification of potential patient selection biomarkers • The ideal candidate will have recent experience supporting oncology drug discovery • Provide hands-on support to build out DF genetics and genomics databases • Develop analytics for common genetic and genomic data use cases and help integrate them into reusable applications • Provide genomic data analysis as needed to support DF discovery project review and progression, including consulting with academic labs to ensure sound methods and interpretation of data • Provide bioinformatics consulting for Deerfield portfolio companies that lack internal expertise • Provide training to Deerfield staff, portfolio companies, and collaborators in genomics applications • Participate in the development of the Deerfield drug discovery and development data strategy, including genetics, genomics, assays, chemistry, and clinical data • Contribute to private investment due diligence • Contribute to evaluation of clinical development programs Minimum qualifications • PhD or equivalent training in computational biology, bioinformatics, biostatistics, genetics, or related area • Five years post-graduate research experience, including three years working in target discovery, target validation, and related applications to drug discovery, including work in oncology • Extensive experience conducting hands-on genomic data analysis with tools such as R, Python, and command-line tools • Broad knowledge of public and private genomic data sources and state-of-the-art analysis methods and tools Preferred qualifications • Experience working in or leading multidisciplinary teams • Publication record in peer reviewed journals • Strong understanding of genetic concepts and genome-wide approaches to genetic data analysis and interpretation 3DC provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law

Bioinformatics Engineer

New York, NY
2021/12/18.

POSITION SUMMARY The Simons Foundation is seeking a Bioinformatics/Senior Bioinformatics Engineer (dependant upon experience) to develop and support whole exome and genome sequence data analysis pipelines in both research and operational modalities. This position will report to the Director of Data and Analytics in the informatics group and will work with other engineers and analysts in the... informatics group, as well as with clinical and basic research teams at the foundation. This position will be based in Simons Foundation's offices in New York City. ESSENTIAL FUNCTIONS/RESPONSIBILITIES • Design, develop and operate computational pipelines for next-generation sequencing data • Work on both large-scale projects and small custom tasks that span a wide variety of analysis problems • Develop new and/or improve upon existing algorithms for variant detection (SNPs and indels) and structural variant detection (CNVs, inversions and translocations) for clinical research purposes • Develop and maintain a knowledge base of variants and annotations discovered in processing of samples MINIMUM QUALIFICATIONS Education • Master's degree or higher in bioinformatics, computational sciences or related field. Required Attributes • At least 3+ years' work experience in research-and-development setting in bioinformatics • Experience with next-generation sequencing data • Experience in Linux/Unix cluster environment • Advanced programming skills in Python • Strong background in algorithm development, statistical methods, machine learning and distributed computing. • Extensive knowledge of computational genomics and experience with high-throughput data analysis • Outstanding personal initiative and the ability to work effectively as part of a team • Excellent verbal and written communication skills Desirable Experience • Familiarity with C++, Perl, Matlab and R is desirable. • Familiarity with databases - relational and noSQL - cloud computing and web services is desirable. The Simons Foundation's Diversity Commitment Many of the greatest ideas and discoveries come from a diverse mix of minds, backgrounds and experiences, and we are committed to cultivating an inclusive work environment.The Simons Foundation actively seeks a diverse applicant pool and encourages candidates of all backgrounds to apply.We provide equal opportunities to all employees and applicants for employment without regard to race, religion, color, age, sex, national origin, sexual orientation, gender identity, genetic disposition, neurodiversity, disability, veteran status, or any other protected category under federal, state and local law. PI157775323

Bioinformatics Scientist (Clinical)

Anywhere
2021/12/11.

At Brooks, new ideas, new technologies and new ways of thinking are driving our future. Our customer-focused culture encourages employees to embrace innovation and challenge the status quo with novel thinking and collaborative work relationships. All we accomplish is grounded in our core values of Customer Focus, Achievement, Accountability, Teamwork, Employee Value and Integrity... Want to be part of a company whose goal is to be the best in the world and the best for the world? Apply today! GENEWIZ is seeking a Scientist II, Process Development to join our Next Generation Sequencing team. This position would have a strong focus on Bioinformatics. Responsibilities: • Leverage internal and external resources to develop, validate, implement new wet and dry lab NGS workflows, services, solutions, and platforms • Improve cost, efficiency, and performance of existing wet and dry lab workflows • Research new NGS workflows applicable to GENEWIZ customer base • Communicate project requirements, status, and deadlines with internal teams • Aid in developing Marketing materials and providing internal training to promote new services and solutions • Provide support to Operations team to deliver custom projects • Work with NGS Study Manager team to provide customers with pre-sale consultation and after-sale technical support Qualifications: • MS or PhD in Biological Sciences, required • Broad understanding of NGS required • Up to date on new NGS technologies including single cell RNA-seq, spatial transcriptomics and long read technologies (Pacbio, Oxford Nanopore) • Deep understanding oncology/immuno oncology preferred • Strong knowledge of next-generation sequencing, including wet and dry lab, required • Hands-on next-generation sequencing wet and dry lab experience, preferred • Strong track record of wet and/or dry lab assay development, required • Strong communication and interpersonal skills, both verbal and written • Ability to multitask and meet deadlines in a fast-paced, customer-oriented environment EOE M/F/Disabled/VET

Genome Bioinformatics Analyst

Pittsburgh, PA
2021/12/11.

• *Description** UPMC Presbyterian is hiring a Genome Bioinformatics Analyst to join the Molecular and Genomic Pathology Laboratory (MGP) team! This role will work a daylight schedule Monday through Friday. No weekends or holidays are required... The Molecular and Genomic Pathology Laboratory (MGP) is a dynamic state-of-the-art clinical laboratory that prides itself on providing the highest quality of patient care in the fields of inherited diseases, hematological malignancies, and solid tumors utilizing cutting-edge molecular testing platforms and informatics approaches exemplified by next-generation sequencing. MGP offers its staff a challenging and rewarding career by offering a wide variety of job responsibilities as well as opportunities to identify and build upon individual strengths. MGP promotes lab-wide collaboration and teamwork where each staff member is valued for the unique skill set they can offer the team. • *Purpose:** The Genome Bioinformatics Analyst works independently to curate disease, gene, and variant knowledge including variant interpretation, reporting, and consultation with laboratory staff, physicians, and genetic counselors. The analyst participates in clinical test development, validation, and maintenance of data analysis pipelines, monitoring of quality metrics, and the analysis of large datasets. This position is ideal for a post-doctoral candidate, who is interested in a career in clinical genomics and molecular diagnostics. • *Responsibilities:** + Designs and executes clinical validation studies to assess diagnostic test performance. + Curates disease, gene, and variant knowledge. + Helps implement curated knowledge, resources, and workflows into clinical operations. + Participates in developmental and clinical research projects, as needed. + Maintains SOP documentation of NGS bioinformatics pipeline. + In consultation with laboratory staff, physicians, and genetic counselors, participates in the review of patient results and develops interpretations for clinical reports. + Participates in clinical test development as needed. + Evaluates novel platforms and techniques in DNA sequencing, genotyping, and copy-number variation in order to assess suitability for diagnostic application. + Maintains data analysis pipelines, monitors quality metrics and analyzes data sets. • *Qualifications** + PhD in molecular biology, human genetics, bioinformatics, computational biology or related field. + MS degree may be considered with 2 or more years of relevant experience. + Strong experience with standard molecular genetics technologies and Next Generation Sequencing. + Familiarity with NGS datasets + Solid understanding of genetic variants within context of disease. + Familiarity with commonly used databases (HGMD, ExAC 1000 genomes), and bioinformatics tools (samtools, IGV, ANNOVAR, GATK) and file formats (BED, VCR, FASTQ, BAM) preferred. + Ability to search for and read literature related to detected variant significance. + Strong analytical and organizational skills. + Works effectively with interdisciplinary team scientists, physicians, genetic counselors. + Must demonstrate a high degree of professionalism, enthusiasm, and initiative on a daily basis. + Ability to work in a fast-paced environment. + Attention to detail is critical. • *Licensure, Certifications, and Clearances:** + Act 34 • *UPMC is an Equal Opportunity Employer/Disability/Veteran** REQNUMBER: 541204720

Staff Bioinformatics Scientist

West Menlo Park, CA
2021/12/11.

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science... to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. GRAIL, LLC is a wholly-owned subsidiary of Illumina, Inc. (NASDAQ:ILMN). For more information, please visit www.grail.com. In this role, you will work with a team of talented scientists to develop state of the art assays to detect cancer signals at an early stage. You will be involved in the design of experiments, analysis of the raw data and interpretation of the results to improve assay performance. You will lead analytical efforts to characterize and improve assay attributes to make them more efficient and sensitive. You will also design and perform simulation studies to evaluate the effect of assay modifications on the classification results. You Will: • Act as a core member of the R&D team leading the analytical aspects of new assay development. • Support a team of assay scientists to characterize and evaluate assay performance. • Run in silico experiments to simulate assay modifications and characterize assay attributes. • Perform complex analysis of large genomic data sets. • Present project updates, data analysis, and experimental conclusions at technical meetings. Your Background Includes: • Master or PhD in computational biology, bioinformatics, statistics, biological sciences, cancer biology, genetics, genomics, computer science, physics, engineering, or equivalent preparation and experience. • In-depth knowledge of genomics, epigenetics, and Next Generation Sequencing workflows. • Preferred, 3 years of relevant experience in positions of increasing responsibility. • Demonstrated expertise in at least one programming language (R, Python, Go.) • Proficiency in Linux environment, version control tools, and reproducible research practices. • Proven knowledge of statistics. • Demonstrated ability to uncover new biological insights from large genomics datasets. • Effective written and verbal communication skills. • Ability to multitask as needed in a complex environment. GRAIL is an Equal Employment Office and Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. We will reasonably accommodate all individuals with disabilities so that they can participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Following extensive monitoring, research, consideration of business implications, and advice from internal and external experts, GRAIL has made the decision to require all U.S. employees receive the COVID-19 vaccines as a condition of employment. “Full vaccination” is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation

Bioinformatician

Anywhere
2021/12/11.

Position: · Freelance... · Fully remote · Flexible schedule · No visa sponsorship available Qualifications: · PhD in computational biology/bioinformatics/computer science/mathematics, or related field · Minimum 4 years experience in bioinformatics · Experience in the analysis of large-scale omics data · Experience in machine learning or other modeling methods · Scripting in Python and/or R · English fluency

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